Nat Commun July 2023 PMID 37414760

SpatialDM for rapid identification of spatially co-expressed ligand-receptor and revealing cell-cell communication patterns.

Zhuoxuan Li, Tianjie Wang, Pentao Liu, Yuanhua Huang

Mentions

15
Peak: 14 in Jul 2023
across 2 sources since Jul 2023

Extended reach

318,447
potential audience

Total likes

51

Video views

11

Mentions per month

Jul 2023 – Oct 2023

Where it's discussed

  • X / Twitter14 posts
  • YouTube1 videos

AI synopsis

What people are saying

The overall digital discussions are neutral, primarily consisting of sharing the article with hashtags related to biotech and spatial transcriptomics, such as #spatialtranscriptomics and #singlecell, and mentioning associated users and publishers. The tone is factual and informational, with little indication of critical analysis or enthusiasm, reflecting a moderate level of interest and engagement without strong opinions or emphasis on impact.

AgreementNeither agree nor disagree

The discussions do not express clear agreement or disagreement with the publication; they mainly acknowledge its content and source.

InterestNeutral interest

Participants show neutral interest, mostly sharing the publication without deeply engaging with its implications.

EngagementModerate engagement

There is some engagement through mentions of specific tags and the sharing of the research, indicating mild interest.

ImpactNeutral impact

The discussions appear informational but do not seem to suggest strong immediate impact or revolutionary effects based solely on these posts.

Abstract in brief

  • SpatialDM is a statistical tool that quickly identifies pairs of genes (ligands and receptors) that are expressed together in specific spatial locations, helping to reveal cell-to-cell communication patterns.
  • Unlike previous methods, SpatialDM focuses on pinpointing exact interaction spots in the tissue, providing single-spot resolution and scalable analysis even for millions of cells.
  • It has been tested on various datasets, showing its effectiveness in uncovering meaningful communication signals between cells and differences in interactions across different biological conditions.

Top posts

Most liked on X and Bluesky
Qian Cheng
@sgqcheng · X

SpatialDM for rapid identification of spatially co-expressed ligand–receptor and revealing cell–cell communication patterns ⁦@YuanhuaHuang⁩ ⁦@NatureComms⁩ #BiotechNatureComms #spatialtranscriptomics #singlecell https://t.co/noWpWNnWPa

Jul 7, 2023 · 51 likes · 13 shares · 601 followers View post →
The Innovation | Medicine
@Innov_Medicine · X

RT @sgqcheng: SpatialDM for rapid identification of spatially co-expressed ligand–receptor and revealing cell–cell communication patterns ⁦…

Jul 7, 2023 · 13 shares · 253,980 followers View post →
Ming "Tommy" Tang
@tangming2005 · X

RT @sgqcheng: SpatialDM for rapid identification of spatially co-expressed ligand–receptor and revealing cell–cell communication patterns ⁦…

Jul 7, 2023 · 13 shares · 40,949 followers View post →
Hao Yin
@HaoYin20 · X

RT @sgqcheng: SpatialDM for rapid identification of spatially co-expressed ligand–receptor and revealing cell–cell communication patterns ⁦…

Jul 7, 2023 · 13 shares · 12,230 followers View post →
Eytan Ruppin, MD, PhD
@EytanRuppin · X

RT @sgqcheng: SpatialDM for rapid identification of spatially co-expressed ligand–receptor and revealing cell–cell communication patterns ⁦…

Jul 7, 2023 · 13 shares · 5,055 followers View post →
Phenomics
@Phenomics_J · X

RT @sgqcheng: SpatialDM for rapid identification of spatially co-expressed ligand–receptor and revealing cell–cell communication patterns ⁦…

Jul 9, 2023 · 13 shares · 1,528 followers View post →

All mentions

NingLiu
@lnly0311 · X

RT @sgqcheng: SpatialDM for rapid identification of spatially co-expressed ligand–receptor and revealing cell–cell communication patterns ⁦…

Jul 10, 2023 · 13 shares · 207 followers View post →
Raj
@raj_jesudason · X

RT @sgqcheng: SpatialDM for rapid identification of spatially co-expressed ligand–receptor and revealing cell–cell communication patterns ⁦…

Jul 10, 2023 · 13 shares · 17 followers View post →
Phenomics
@Phenomics_J · X

RT @sgqcheng: SpatialDM for rapid identification of spatially co-expressed ligand–receptor and revealing cell–cell communication patterns ⁦…

Jul 9, 2023 · 13 shares · 1,528 followers View post →
Chayan Mukherjee
@ChayanM91517533 · X

RT @sgqcheng: SpatialDM for rapid identification of spatially co-expressed ligand–receptor and revealing cell–cell communication patterns ⁦…

Jul 8, 2023 · 13 shares · 224 followers View post →
Dr. Andrea Komljenovic
@antifreezeprot · X

RT @sgqcheng: SpatialDM for rapid identification of spatially co-expressed ligand–receptor and revealing cell–cell communication patterns ⁦…

Jul 8, 2023 · 13 shares · 427 followers View post →
lbgbox
@lbgbox · X

RT @sgqcheng: SpatialDM for rapid identification of spatially co-expressed ligand–receptor and revealing cell–cell communication patterns ⁦…

Jul 8, 2023 · 13 shares · 52 followers View post →
Jun-Liszt Li
@poppingjun · X

RT @sgqcheng: SpatialDM for rapid identification of spatially co-expressed ligand–receptor and revealing cell–cell communication patterns ⁦…

Jul 7, 2023 · 13 shares · 1,019 followers View post →
Eytan Ruppin, MD, PhD
@EytanRuppin · X

RT @sgqcheng: SpatialDM for rapid identification of spatially co-expressed ligand–receptor and revealing cell–cell communication patterns ⁦…

Jul 7, 2023 · 13 shares · 5,055 followers View post →
Hao Yin
@HaoYin20 · X

RT @sgqcheng: SpatialDM for rapid identification of spatially co-expressed ligand–receptor and revealing cell–cell communication patterns ⁦…

Jul 7, 2023 · 13 shares · 12,230 followers View post →
Reinaldo F Cristo
@rcristo · X

RT @sgqcheng: SpatialDM for rapid identification of spatially co-expressed ligand–receptor and revealing cell–cell communication patterns ⁦…

Jul 7, 2023 · 13 shares · 1,403 followers View post →
The Innovation | Medicine
@Innov_Medicine · X

RT @sgqcheng: SpatialDM for rapid identification of spatially co-expressed ligand–receptor and revealing cell–cell communication patterns ⁦…

Jul 7, 2023 · 13 shares · 253,980 followers View post →
Ming "Tommy" Tang
@tangming2005 · X

RT @sgqcheng: SpatialDM for rapid identification of spatially co-expressed ligand–receptor and revealing cell–cell communication patterns ⁦…

Jul 7, 2023 · 13 shares · 40,949 followers View post →
qicy
@qicy11 · X

RT @sgqcheng: SpatialDM for rapid identification of spatially co-expressed ligand–receptor and revealing cell–cell communication patterns ⁦…

Jul 7, 2023 · 13 shares · 381 followers View post →
Qian Cheng
@sgqcheng · X

SpatialDM for rapid identification of spatially co-expressed ligand–receptor and revealing cell–cell communication patterns ⁦@YuanhuaHuang⁩ ⁦@NatureComms⁩ #BiotechNatureComms #spatialtranscriptomics #singlecell https://t.co/noWpWNnWPa

Jul 7, 2023 · 51 likes · 13 shares · 601 followers View post →