Biol Sex Differ July 2023 PMID 37420305

Sex- and age-specific effects on the development of addiction and compulsive-like drinking in rats.

Jerome C Foo, Ivan Skorodumov, Rainer Spanagel, Marcus W Meinhardt

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Peak: 3 in Jul 2023

across 2 sources since Jul 2023

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14,426

potential audience

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Jul 2023 – Oct 2023

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What people are saying

The overall discussions show a positive interest in the article's focus on biological factors influencing addiction, with phrases like 'study using the alcohol deprivation effect' and 'results reveal differences across sex and age groups' reflecting curiosity and acknowledgment of scientific progress. The tone is analytical but also somewhat enthusiastic about the potential implications of the findings.

AgreementModerate agreement

Most discussions acknowledge the relevance of the research, emphasizing the importance of sex and age factors in addiction development, with some highlighting the methodological approach.

InterestHigh interest

The mention of new findings and the use of specific models like the alcohol deprivation effect attract high interest from readers keen on addiction research.

EngagementModerate engagement

Comments include references to system implementations like the drinkometer and discussions about how these findings might alter understanding of addiction mechanisms, indicating moderate engagement.

ImpactModerate impact

While readers recognize the significance of the research for future studies and potential implications, the posts mainly focus on summarization rather than extensive critique or calls to action.

Abstract in brief

The study examines how sex and age influence alcohol drinking behavior and addiction development in rats, highlighting that female rats tend to drink more alcohol overall, especially at lower concentrations, and display different circadian patterns of movement compared to males.
Early onset of drinking in male rats (around postnatal day 40) had minimal impact on their development of compulsive drinking behaviors compared to those that started drinking in early adulthood (postnatal day 72), suggesting that age at first experience with alcohol influences addiction patterns differently across sexes.
These findings emphasize the importance of biological factors like sex and age in understanding alcohol addiction, and show that female rats' drinking behavior is driven by larger access sizes, with sex-specific differences in how drinking patterns and compulsivity develop over time.]

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All mentions

Sex and Age Effects on Alcohol Addiction Development in Rats

This study examines how sex and age influence alcohol drinking behavior and addiction development in rats, highlighting differences in drinking patterns and compulsivity between males and females.

Medicine RTCL TV · Oct 22, 2023 29 views

Jibran Khokhar

@DrJKhokhar · X

RT @BiologySexDiff: New article: Researchers used the alcohol deprivation effect (ADE) rat model of alcohol addiction in a computerized dri…

Jul 12, 2023 · 3 shares · 10,820 followers View post →

Dr. Jill Becker

@women_neurosci · X

RT @BiologySexDiff: New article: Researchers used the alcohol deprivation effect (ADE) rat model of alcohol addiction in a computerized dri…

Jul 12, 2023 · 3 shares · 1,643 followers View post →

Biology of Sex Differences

@BiologySexDiff · X

Jul 12, 2023 · 5 likes · 3 shares · 1,917 followers View post →