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The discussions generally reflect positive acknowledgment of the research, emphasizing its relevance to understanding muscle aging, especially in relation to humans. For example, terms like 'more profound gene changes' and 'mirrored by more human-like aging' illustrate the perception that this work significantly advances knowledge. The tone, which often highlights scientific advances and methodological rigor, underscores a respectful engagement with the study’s implications.
Most discussions acknowledge the study’s findings, with some emphasizing its relevance to humans and endorsing the results. For example, references to rats showing more human-like aging patterns reflect positive reception.
Posts show high curiosity, with multiple mentions of the research’s methodology and significance. Phrases like 'robust sarcopenia phenotype' and 'multi-timepoints' indicate true engagement with the scientific details.
Comments include recognition of the study’s contributions and some discussion of specific findings, such as gene expression changes and similarities across species, demonstrating moderate but meaningful involvement.
While some users highlight the potential therapeutic implications, overall, posts suggest a recognition of scientific importance rather than a perception of immediate societal change, resulting in moderate impact perception.
New paper from our lab, showing age-related gene changes (multi-timepoints) in rats vs mice. Rats undergo a more robust sarcopenia phenotype, and this is mirrored by more profound gene changes... perhaps more reminiscent of the human than mice. https://t.co/79oO3lQVrt
Two consistent findings that we see with age: inflammatory signaling increases - including innate immunity signaling - and the extracellular matrix is perturbed. In rats, you also see a decrease in mito gene expression... perhaps more in line with humans. https://t.co/79oO3lQnBV
This study by @davidjglassMD and team at @Regeneron shows that the #SkeletalMuscle in rats
Congrats to @davidjglassMD and colleagues for their new #skeletalmuscle paper: Age-related gene expression signatures from limb skeletal muscles and the diaphragm in mice and rats reveal common and species-specific changes. https://t.co/f6IeYwazJP
Age-related gene expression signatures from limb skeletal muscles and the diaphragm in mice and rats reveal common and species-specific changes @TShavlakad83101, @davidjglassMD et al. https://t.co/6xUH5iUUbT https://t.co/mILEKgPPtj
New paper from David Glass’ lab, showing age-related gene changes (over multiple timepoints throughout the lifespan of the models) in rats vs mice. https://t.co/KzstWaKA2m
This study investigates sarcopenia by analyzing gene expression changes in skeletal muscles of mice and rats, revealing common and species-specific aging patterns, with implications for human muscle aging research.
@PGreenhaff @OchDr @jpsenescence @AbigailMackey1 Completely agree, especially for humans. For rats, we referred to https://t.co/ydw5nLF7iZ where they observed over 40% decrease in rat limb muscle at 27 months of age. Of course mass is not the only measurement of sarcopenia, thanks for the suggestion
RT @davidjglassMD: Two consistent findings that we see with age: inflammatory signaling increases - including innate immunity signaling - a…
RT @davidjglassMD: Two consistent findings that we see with age: inflammatory signaling increases - including innate immunity signaling - a…
RT @davidjglassMD: Two consistent findings that we see with age: inflammatory signaling increases - including innate immunity signaling - a…
RT @davidjglassMD: Two consistent findings that we see with age: inflammatory signaling increases - including innate immunity signaling - a…
Two consistent findings that we see with age: inflammatory signaling increases - including innate immunity signaling - and the extracellular matrix is perturbed. In rats, you also see a decrease in mito gene expression... perhaps more in line with humans. https://t.co/79oO3lQnBV
New paper from David Glass’ lab, showing age-related gene changes (over multiple timepoints throughout the lifespan of the models) in rats vs mice. https://t.co/KzstWaKA2m
RT @musclecellnews: This study by @davidjglassMD and team at @Regeneron shows that the #SkeletalMuscle in rats
RT @musclecellnews: This study by @davidjglassMD and team at @Regeneron shows that the #SkeletalMuscle in rats
RT @musclecellnews: This study by @davidjglassMD and team at @Regeneron shows that the #SkeletalMuscle in rats
This study by @davidjglassMD and team at @Regeneron shows that the #SkeletalMuscle in rats
RT @agingdoc1: Age-related gene expression signatures from limb skeletal muscles and the diaphragm in mice and rats reveal common and speci…
RT @agingdoc1: Age-related gene expression signatures from limb skeletal muscles and the diaphragm in mice and rats reveal common and speci…
RT @agingdoc1: Age-related gene expression signatures from limb skeletal muscles and the diaphragm in mice and rats reveal common and speci…
Age-related gene expression signatures from limb skeletal muscles and the diaphragm in mice and rats reveal common and species-specific changes @TShavlakad83101, @davidjglassMD et al. https://t.co/6xUH5iUUbT https://t.co/mILEKgPPtj
RT @davidjglassMD: New paper from our lab, showing age-related gene changes (multi-timepoints) in rats vs mice. Rats undergo a more robust…
RT @davidjglassMD: New paper from our lab, showing age-related gene changes (multi-timepoints) in rats vs mice. Rats undergo a more robust…
RT @davidjglassMD: New paper from our lab, showing age-related gene changes (multi-timepoints) in rats vs mice. Rats undergo a more robust…
Age-related gene expression signatures from limb skeletal muscles and the diaphragm in mice and rats reveal common and species-specific changes. Skeletal Muscle 13, 11 (12 July 2023) https://t.co/FnXBSPmec2 https://t.co/q2965Dayq0
RT @davidjglassMD: New paper from our lab, showing age-related gene changes (multi-timepoints) in rats vs mice. Rats undergo a more robust…
RT @davidjglassMD: New paper from our lab, showing age-related gene changes (multi-timepoints) in rats vs mice. Rats undergo a more robust…
RT @davidjglassMD: New paper from our lab, showing age-related gene changes (multi-timepoints) in rats vs mice. Rats undergo a more robust…
RT @davidjglassMD: New paper from our lab, showing age-related gene changes (multi-timepoints) in rats vs mice. Rats undergo a more robust…
RT @davidjglassMD: New paper from our lab, showing age-related gene changes (multi-timepoints) in rats vs mice. Rats undergo a more robust…
New paper from our lab, showing age-related gene changes (multi-timepoints) in rats vs mice. Rats undergo a more robust sarcopenia phenotype, and this is mirrored by more profound gene changes... perhaps more reminiscent of the human than mice. https://t.co/79oO3lQVrt
RT @Matt_Muscle_Guy: Congrats to @davidjglassMD and colleagues for their new #skeletalmuscle paper: Age-related gene expression signatures…
RT @Matt_Muscle_Guy: Congrats to @davidjglassMD and colleagues for their new #skeletalmuscle paper: Age-related gene expression signatures…
RT @Matt_Muscle_Guy: Congrats to @davidjglassMD and colleagues for their new #skeletalmuscle paper: Age-related gene expression signatures…
RT @Matt_Muscle_Guy: Congrats to @davidjglassMD and colleagues for their new #skeletalmuscle paper: Age-related gene expression signatures…
RT @Matt_Muscle_Guy: Congrats to @davidjglassMD and colleagues for their new #skeletalmuscle paper: Age-related gene expression signatures…
Congrats to @davidjglassMD and colleagues for their new #skeletalmuscle paper: Age-related gene expression signatures from limb skeletal muscles and the diaphragm in mice and rats reveal common and species-specific changes. https://t.co/f6IeYwazJP