July 2023 PMID 37451735

Effects of vitamins K2 and D3 supplementation in patients with severe coronary artery calcification: a study protocol for a randomised controlled trial.

Selma Hasific, Kristian A Øvrehus, Susanne Hosbond, Jess Lambrechtsen, Preman Kumarathurai, Anna Mejldal, Emil Johannes Ravn, Lars Melholt Rasmussen, Oke Gerke, Hans Mickley, Axel Diederichsen

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Mentions

8
Peak: 2 in Aug 2024
across 3 sources since Jul 2023

Extended reach

1,564
potential audience

Total likes

42

Video views

626

Mentions per month

Jul 2023 – Nov 2024

Where it's discussed

  • X / Twitter3 posts
  • News3 articles
  • YouTube2 videos

AI synopsis

What people are saying

The overall tone reflects cautious curiosity, with posts like '@rand_longevity' mentioning known benefits and '@SoylentGreenGo' highlighting the current limited scientific evidence. The tone is informal and somewhat speculative, emphasizing ongoing research but not fully endorsing the study's results, which influences the moderate scores across the dimensions.

AgreementModerate agreement

Most discussions suggest a cautious or tentative agreement, acknowledging potential benefits of vitamin K2 and D3 but noting limited conclusive evidence.

InterestModerate interest

Users show moderate interest, referencing general health benefits and ongoing research rather than deep analysis.

EngagementNeutral engagement

Comments are somewhat superficial; there is limited in-depth discussion of the study's methodology or findings.

ImpactModerate impact

The conversations recognize the importance of the topic, particularly around supplementation and health impacts, but do not indicate transformative effects.

Abstract in brief

  • This study investigates whether supplementing with vitamins K2 and D3 can slow the progression of coronary artery calcification (CAC), which is a strong predictor of heart attack and cardiovascular death, in men and women with severe CAC.
  • It is a 2-year, multicenter, double-blind, placebo-controlled trial involving 400 participants, where the primary focus is to measure changes in CAC scores through cardiac CT scans at baseline, 12 months, and 24 months.
  • The study aims to determine the effects of vitamin K2 and D3 on CAC progression, with secondary goals including changes in plaque composition and occurrence of cardiac events, and emphasizes that no adverse effects of vitamin K2 have been reported so far.]

Top posts

Most liked on X and Bluesky
David Andersen
@davidx · X

@rand_longevity there's plenty, havent looked into but pubmed has som e, just the general benefits known of vitamin d and its relationship with k2 https://t.co/eBo9WojrHs

Nov 12, 2024 · 790 followers View post →
Tac
@TheOnlyTacsir · X

@SoylentGreenGo @MelonieMac There is currently no evidence that shows this. However it is believed (not by science) that K2 minimises any further progression of CAC, and trials are currently be run on K2+D3 supplementation vs placebos. https://t.co/oQm4IXBciF

Aug 7, 2023 · 105 followers View post →

All mentions

David Andersen
@davidx · X

@rand_longevity there's plenty, havent looked into but pubmed has som e, just the general benefits known of vitamin d and its relationship with k2 https://t.co/eBo9WojrHs

Nov 12, 2024 · 790 followers View post →
Tac
@TheOnlyTacsir · X

@SoylentGreenGo @MelonieMac There is currently no evidence that shows this. However it is believed (not by science) that K2 minimises any further progression of CAC, and trials are currently be run on K2+D3 supplementation vs placebos. https://t.co/oQm4IXBciF

Aug 7, 2023 · 105 followers View post →
ACHS Research
@AchsResearch · X

New NUTRITION Research Available. Click Here to Access Article(s): https://t.co/mu7boa6NZd

Jul 17, 2023 · 44 followers View post →