Trends Pharmacol Sci December 2023 PMID 37500295

Human skin-on-a-chip for mpox pathogenesis studies and preclinical drug evaluation.

Jia Zhu, Hasan E Abaci

Mentions

114
Peak: 9 in Sep 2025
across 8 sources since Jul 2023

Extended reach

203,336
potential audience

Total likes

220

Video views

14,685

Mentions per month

Jul 2023 – Dec 2025

Where it's discussed

  • Facebook50 posts
  • Instagram36 posts
  • Reddit13 posts
  • LinkedIn7 posts
  • X / Twitter4 posts
  • YouTube2 videos
  • TikTok1 posts
  • Blogs1 articles

AI synopsis

What people are saying

The collective discussions highlight the innovative approach of using human skin-on-a-chip models to study mpox, with phrases like 'valuable model' and 'potential for evaluation' emphasizing its importance. The tone indicates modest enthusiasm, focusing on the research's potential benefits for understanding and preventing mpox outbreaks.

AgreementModerate agreement

Most discussions acknowledge the significance of the skin-on-a-chip technology for mpox research, indicating general support.

InterestModerate interest

Participants show curiosity about the research, with posts mentioning the paper and its potential uses, but the tone remains somewhat neutral.

EngagementModerate engagement

Posts reference methodologies, such as 'preclinical drug evaluation,' and reflect an intellectual engagement with the topic.

ImpactModerate impact

The discussions suggest that this research could influence future studies and public health measures, though the language remains exploratory.

Abstract in brief

  • The text discusses the use of a human skin-on-a-chip model to study mpox (monkeypox) disease, which became a global concern in 2022.
  • The model aims to better understand how mpox spreads and affects human skin, helping researchers evaluate drugs and treatments before clinical trials.
  • Using this technology could improve our ability to predict the success of therapies and develop more effective preventative measures for mpox.]

Top posts

Most liked on X and Bluesky
UW Virology
@UWVirology · X

New paper from the Zhu Lab: Human skin-on-a-chip for mpox pathogenesis studies and preclinical drug evaluation! Read it here: https://t.co/QrsrpG13o6

Jul 26, 2023 · 7 likes · 1 share · 182,809 followers View post →
FlowJEM Microfluidics
@FlowJEM · X

Timely intervention of preventative and therapeutic measures abated a 2022 monkeypox global outbreak. The potentials of human #skin-on-a-chip as a valuable model for #mpox disease evaluation are discussed by Abaci et al. at https://t.co/IWAQX3GIK0

Jul 31, 2023 · 2 likes · 1 share · 381 followers View post →
Trends in Pharmacological Sciences
@TrendsinPharma · X

Human skin-on-a-chip for mpox pathogenesis studies and preclinical drug evaluation https://t.co/5pt1KqwaNT

Sep 7, 2023 · 1 like · 1 share · 3,240 followers View post →
Ace Bryan Sotelo Cabal
@ace_cabal · X

RT @UWVirology: New paper from the Zhu Lab: Human skin-on-a-chip for mpox pathogenesis studies and preclinical drug evaluation! Read it her…

Aug 15, 2023 · 1 share · 1,134 followers View post →

All mentions

Trends in Pharmacological Sciences
@TrendsinPharma · X

Human skin-on-a-chip for mpox pathogenesis studies and preclinical drug evaluation https://t.co/5pt1KqwaNT

Sep 7, 2023 · 1 like · 1 share · 3,240 followers View post →
Ace Bryan Sotelo Cabal
@ace_cabal · X

RT @UWVirology: New paper from the Zhu Lab: Human skin-on-a-chip for mpox pathogenesis studies and preclinical drug evaluation! Read it her…

Aug 15, 2023 · 1 share · 1,134 followers View post →
FlowJEM Microfluidics
@FlowJEM · X

Timely intervention of preventative and therapeutic measures abated a 2022 monkeypox global outbreak. The potentials of human #skin-on-a-chip as a valuable model for #mpox disease evaluation are discussed by Abaci et al. at https://t.co/IWAQX3GIK0

Jul 31, 2023 · 2 likes · 1 share · 381 followers View post →
UW Virology
@UWVirology · X

New paper from the Zhu Lab: Human skin-on-a-chip for mpox pathogenesis studies and preclinical drug evaluation! Read it here: https://t.co/QrsrpG13o6

Jul 26, 2023 · 7 likes · 1 share · 182,809 followers View post →
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פשוט כיביתי את הקולות מבחוץ וצללתי פנימה. יצאתי להליכה בטבע כדי לנקות ...
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... 10.1016/j.physrep. 2023.07.001 ולמי שרוצה להצטרף לשיעורי יוגה: www.shlomut.com/studio · No photo description available. Dvora Mivtzari and 2 ...

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Protein controlling chromatin architecture also maintains lipid ...
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... 10.1016/j. chembiol.2023.07.001 Targeting transcription replication conflicts, a major source of endogenous DNA double-stranded breaks and ...

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A male client is receiving the cell cycle–nonspecific alkylating agent ...
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... 10.1016/j. chembiol.2023.07.001 Targeting transcription replication ... Yasko also thinks that a little Lithium Orotate 5 mg/day may help vitamin ...

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All of the following are considered as inhibitors for PRPP synthetase ...
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In the drug interactions chapter, do anyone have tips / notes ... 10.1016/j. chembiol.2023.07.001 Targeting transcription replication ...

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Which of the following is the mechanism of action of vinblastine? A ...
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... help unwind DNA for replication 5. Mitotic Inhibitors (Plant ... 10.1016/j. chembiol.2023.07.001 Targeting transcription replication ...

Jul 26, 2021 View →
Small-molecule inhibitors of human mitochondrial DNA transcription
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... 10.1016/j. chembiol.2023.07.001 Targeting transcription replication conflicts, a major source of endogenous DNA double-stranded breaks and ...

Dec 19, 2020 View →
שְׁלוֹמוּת - האימון - מייצר הזדמנות להיזכר. השבוע התאמנו עם הטקס ...
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... 10.1016/j.physrep. 2023.07.001 ולמי שרוצה להצטרף לשיעורי יוגה: www.shlomut.com/studio · No photo description available. Dvora Mivtzari and 2 ...

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A male client is receiving the cell cycle–nonspecific alkylating agent ...
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... tips Comment “CONSULT” if you want to work with me personally ... 10.1016/j. chembiol.2023.07.001 Targeting transcription replication ...

Apr 25, 2019 View →
“We found that... - The University of Kansas Cancer Center | Facebook
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... 10.1016/j. chembiol.2023.07.001 Targeting transcription replication ... These findings may help to understand the mechanisms of LEC ...

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What is the mechanism of action of the antiviral agent ribavirin ...
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... Tip: Always ensure adequate hydration, especially in IV use, to ... 10.1016/j. chembiol.2023.07.001 Targeting transcription replication ...

Nov 3, 2018 View →
A male client is receiving the cell cycle–nonspecific alkylating agent ...
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... 10.1016/j. chembiol.2023.07.001 Targeting transcription replication ... tips Comment “CONSULT” if you want to work with me personally ...

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A new antibiotic was discovered which strongly inhibited mRNA ...
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... 10.1016/j. chembiol.2023.07.001 Targeting transcription replication ... help save some of the estimated 1.1 million people who die each ...

May 28, 2018 View →
A new antibiotic was discovered which strongly inhibited mRNA ...
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... help of computer models of bacterial gene products capable of ... 10.1016/j. chembiol.2023.07.001 Targeting transcription replication ...

May 28, 2018 View →
PRINCIPLES OF CANCER THERAPY: MECHANISMS OF ACTION ...
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10.1016/j.dnarep. 2007.03.007 [PMC free article] [PubMed] [CrossRef] ... chembiol.2023.07.001 Targeting transcription replication ...

Mar 10, 2018 View →
A new antibiotic was discovered which strongly inhibited mRNA ...
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... advice. Always consult a qualified doctor before starting or ... 10.1016/j. chembiol.2023.07.001 Targeting transcription replication ...

Feb 19, 2018 View →
משהו מרחיב לב ומענג בהונות קורה באור בך בית לבריאות. בוגרי שנה ב' של ...
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... 10.1016/j.physrep. 2023.07.001 ולמי שרוצה להצטרף לשיעורי יוגה: www.shlomut.com/studio · No photo description available. Dvora Mivtzari and 2 ...

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Hospital Clínico Universitario de Valladolid http://www.aeped.es ...
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... 10.1016/j. anpedi.2023.07.001 · May be an image of text · Marcos JF and 6 others ·

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#السؤال_البديل Function of small interfering Ribonucleic Acids ...
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What is the mechanism of action of cisplatin? Stabilises DNA ...
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Knowing the chemical structure of the protein will likely help drug designers build novel #anti-#cancer agents. ... 10.1016/j. chembiol.2023.07.

Mar 23, 2017 View →
DNA-replication is by the mechanism of (a) Conservative (b ...
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... 10.1016/j. chembiol.2023.07.001 Targeting transcription replication conflicts, a major source of endogenous DNA double-stranded breaks and ...

Oct 10, 2016 View →
Which of the following is not inhibitor of DNA synthesis: A. 5- amino ...
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Carrie Madej suggests regular detox baths with Bentonite Clay to help your body remove GO Nanoparticles. ... 10.1016/j. chembiol.2023.07.001 ...

Jul 4, 2016 View →
Lynchpin Molecule for Spread of Cancer found #DNA-#PKcs ...
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... 10.1016/j. chembiol.2023.07.001 Targeting transcription replication conflicts, a major source of endogenous DNA double-stranded breaks and ...

Jul 13, 2015 View →
A new publication by Dr. Rupan Sandhu in Breast Cancer Research ...
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Experimental Vaccine May Help Reduce Recurrence Risk of HER2-Positive Disease ... 10.1016/j. chembiol.2023.07.001 Targeting transcription ...

Jan 6, 2012 View →