Overall, discussions show high interest and moderate engagement, with examples like mentions of the broad antiviral activity of peptidomimetic oligomers and their membrane-specific targeting mechanism. The tone ranges from celebratory acknowledgments to technical explanations, illustrating recognition of the research's significance and potential real-world applications.
AgreementModerate agreement
Most discussions express positive recognition of the study's significance, highlighting its novelty and potential impact, though some innocuous comments suggest general acknowledgment rather than strong endorsement.
InterestHigh interest
The discussions reflect high interest, with many posts emphasizing the broad antiviral activity and innovations in targeting viral membranes, demonstrating engagement with the scientific content.
EngagementModerate engagement
Participants show moderate engagement by referencing specific aspects such as the membrane-specific mechanism and the therapeutic potential, along with personal contributions like PhD work and recognition of the authors.
ImpactModerate impact
The collective tone indicates that the publication is considered to have a notable impact on antiviral research and therapeutic development, especially given references to broad activity and resistance mitigation.
Abstract in brief
Peptidomimetic oligomers called peptoids can directly target and disable various enveloped viruses, including Zika and chikungunya, by disrupting their membranes.
These peptoids specifically interact with phosphatidylserine (PS), a lipid component in viral membranes, leading to membrane disruption, whereas they don't affect membranes with only phosphatidylcholine (PC).
The findings suggest that peptoids work through a membrane-specific mechanism, offering a promising new approach for antiviral therapies that could minimize resistance development.]
my first first-author paper during my PhD is finally out! thank you so much @bryancmounce for letting me still bother you ( even after you FIRED ME ) to complete some of this work. and obviously thank you to @mastvr1 & @christina_cunha for being a dream https://t.co/PEos2X00gS
Aug 2, 2023 · 31 likes · 5 shares · 351 followersView post →
NC
NYU Chemistry
@nyuchemistry · X
ACS Infectious Diseases study "Peptidomimetic Oligomers Targeting Membrane Phosphatidylserine Exhibit Broad Antiviral Activity" is generating attention. Congrats to lead author grad student Patrick Tate and Professor Kent Kirshenbaum! @aroralabnyu
https://t.co/RMigXxoMtc
Aug 2, 2023 · 8 likes · 3,111 followersView post →
Aug 3, 2023 · 4 likes · 3 shares · 43,925 followersView post →
JM
J Scotch McClure
@joshuamcclure · X
@therustychemist @MaxwellBiosci Good question. Good answer:
Here is our 2023 American Chemical Society publication on that topic:
https://t.co/VF8TzpiuJ5
Alright, let's break this down. Imagine viruses as little invaders with either a protective coat, called an enveloped virus, or without one, which we'll
Oct 6, 2023 · 4 likes · 1 share · 18,928 followersView post →
PU
PostX #UniteToFight2024
@TeamPostX · X
Biomimicry with bursting.
Peptidomimetic Oligomers Targeting Membrane Phosphatidylserine establishing an avenue for specificity that may enable the development of a new family of therapeutics capable of averting the rapid development of resistance. https://t.co/SvUZR3g7wN
Article Update! This article published in the August issue of ACS ID, shows the antiviral activity of AMP mimetic peptoids against an array of enveloped viruses, acting through a membrane-specific mechanism.
https://t.co/WaIAYfq5sI
@ACSBioMed #ACSInfectiousDiseases
This week longevity researcher Ryker Black introduces a new nasal spray designed to combat systemic inflammation, also known as inflammaging. The research is based on peer-reviewed studies highlighting inflammation's…
Novel molecules target and disable enveloped viruses like Zika and chikungunya by disrupting their membrane membranes, offering a potential new strategy for antiviral therapy with reduced resistance.
Scientists have developed a peptoid-based antiviral therapy that targets lipid components in virus membranes, disrupting enveloped viruses like Zika and chikungunya by interacting with phosphatidylserine, offering a…
RT @PatrickMTate: my first first-author paper during my PhD is finally out! thank you so much @bryancmounce for letting me still bother you…
Nov 25, 2023 · 5 shares · 177 followersView post →
JM
J Scotch McClure
@joshuamcclure · X
RT @joshuamcclure: @therustychemist @MaxwellBiosci Good question. Good answer:
Here is our 2023 American Chemical Society publication on t…
Oct 6, 2023 · 1 share · 18,928 followersView post →
JM
J Scotch McClure
@joshuamcclure · X
@therustychemist @MaxwellBiosci Good question. Good answer:
Here is our 2023 American Chemical Society publication on that topic:
https://t.co/VF8TzpiuJ5
Alright, let's break this down. Imagine viruses as little invaders with either a protective coat, called an enveloped virus, or without one, which we'll
Oct 6, 2023 · 4 likes · 1 share · 18,928 followersView post →
JH
Jayanta Haldar
@jayanta_amr · X
Article Update! This article published in the August issue of ACS ID, shows the antiviral activity of AMP mimetic peptoids against an array of enveloped viruses, acting through a membrane-specific mechanism.
https://t.co/WaIAYfq5sI
@ACSBioMed #ACSInfectiousDiseases
Biomimicry with bursting.
Peptidomimetic Oligomers Targeting Membrane Phosphatidylserine establishing an avenue for specificity that may enable the development of a new family of therapeutics capable of averting the rapid development of resistance. https://t.co/SvUZR3g7wN
Aug 5, 2023 · 3 shares · 6,617 followersView post →
CB
CD BioSciences
@CDBioSciences · X
Researchers have now developed a new antiviral treatment that ignores the rapidly mutating proteins on the surface of the virus and instead targets the lipids in the enveloped virus membrane, destroying its protective layer.
https://t.co/5iqjyv0zyC
Aug 3, 2023 · 4 likes · 3 shares · 43,925 followersView post →
NC
NYU Chemistry
@nyuchemistry · X
ACS Infectious Diseases study "Peptidomimetic Oligomers Targeting Membrane Phosphatidylserine Exhibit Broad Antiviral Activity" is generating attention. Congrats to lead author grad student Patrick Tate and Professor Kent Kirshenbaum! @aroralabnyu
https://t.co/RMigXxoMtc
Aug 2, 2023 · 8 likes · 3,111 followersView post →
JM
Johannes Morstein
@mo_hannes · X
RT @PatrickMTate: my first first-author paper during my PhD is finally out! thank you so much @bryancmounce for letting me still bother you…
Aug 2, 2023 · 5 shares · 1,304 followersView post →
J
J
@fraaannk · X
RT @PatrickMTate: my first first-author paper during my PhD is finally out! thank you so much @bryancmounce for letting me still bother you…
my first first-author paper during my PhD is finally out! thank you so much @bryancmounce for letting me still bother you ( even after you FIRED ME ) to complete some of this work. and obviously thank you to @mastvr1 & @christina_cunha for being a dream https://t.co/PEos2X00gS
Aug 2, 2023 · 31 likes · 5 shares · 351 followersView post →
F
"Cannabis only produces carbon-based secondary metabolites. Of ...