October 2023 PMID 37558503

Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study.

Carin A Northuis, Elizabeth J Bell, Pamela L Lutsey, Kristen M George, Rebecca F Gottesman, Tom H Mosley, Eric A Whitsel, Kamakshi Lakshminarayan

Mentions

332
Peak: 30 in Aug 2023
across 7 sources since Aug 2023

Extended reach

354,223
potential audience

Total likes

1,036

Video views

22,463

Mentions per month

Aug 2023 – Jun 2025

Where it's discussed

  • News220 articles
  • X / Twitter87 posts
  • Blogs9 articles
  • Facebook6 posts
  • YouTube5 videos
  • Reddit3 posts
  • Bluesky2 posts

AI synopsis

What people are saying

Discussions frequently highlight the alarming statistic of a 33% increase in dementia risk associated with long-term PPI usage. Posts express concern over the high number of individuals using these medications and suggest alternatives to manage symptoms. Words such as 'terrible side effects' or phrases like 'bandaid solutions' indicate a critical tone towards the existing treatment approaches, reflecting a serious concern for patient health outcomes.

AgreementModerate agreement

The majority of discussions lean towards acknowledging the findings of the article, with many expressing concerns about the implications of long-term PPI use.

InterestHigh interest

There is evident curiosity in readers about the relationship between PPIs and dementia risk, indicated by the frequency of shared posts and mentions of related findings.

EngagementHigh engagement

Participants are engaging deeply with the content, analyzing implications, questioning causality, and even referencing other studies and facts about medications.

ImpactHigh impact

Many participants believe the research has significant ramifications for public health and personal medication choices, especially for those already using PPIs.

Abstract in brief

  • The study analyzed the relationship between cumulative use of proton pump inhibitors (PPIs) and the risk of developing dementia using data from the Atherosclerosis Risk in Communities (ARIC) Study, which tracked participants from 1987 to 2017.
  • Results showed that current PPI users at the time of visit 5 did not have a significantly higher risk of developing dementia compared to non-users, but those with over 4 cumulative years of PPI use had a 33% increased risk.
  • The findings imply that while short-term PPI use may not affect dementia risk, long-term use could be associated with higher risk, prompting calls for further research to clarify these associations.

Top posts

Most liked on X and Bluesky
トンヌラ
@37phoenix · X

PPIと認知量リスク。PPI使用者と非使用者で認知症発症リスクに差はなかった。4.4年以上の使用は33%のリスク上昇がみられた。Neurology. PMID: 37558503. https://t.co/Pxjw5CpDYW

Sep 16, 2023 · 28 likes · 2 shares · 2,053 followers View post →
Sergio Calleja
@Montecoya · X

Cumulative Use of Proton Pump Inhibitors and Risk of Dementia | Neurology "Quienes tomaron IPP duante >4.4 años acumulados presentaron un riesgo de demencia un 33% mayor durante el seguimiento (HR: 1.3 [95% CI 1.0–1.8]) que quienes no los tomaron" https://t.co/SvW3x2RXdE

Jul 7, 2024 · 24 likes · 17 shares · 5,687 followers View post →
Dr.ちゃうちゃう先生
@drchauchau · X

PPI(胃酸分泌抑制剤)と認知症との関連についての先行研究では一致した結果は得られていませんが、本研究では、累積で4.4年以上使用した人で使用しなかった人と比べて発症リスクが33%上昇し、その関連性を示唆されました。 https://t.co/W2tjY5RxBG

Jan 5, 2024 · 20 likes · 1 share · 1,796 followers View post →
やすくん
@yasukun6791 · X

PPIの長期使用が認知症の発症を促すってデータがあるくらいだから、脳に何かしらの影響は与えるんだろうけど、これからの研究結果を待ってみます https://t.co/GThtJI3EXe https://t.co/QHOGdsvTO4

Jun 16, 2024 · 15 likes · 4,910 followers View post →
Dr. Paul Cottrell
@dr_cottrell · X

Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study https://t.co/nEdNUmlBaE

Aug 10, 2023 · 11 likes · 1 share · 10,331 followers View post →
DrRPalmquist
@DrPalmquist · X

Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study Cutting carb intake helps many with “heartburn.” Why not try that before acid blockers? https://t.co/Gw7PaA14Np

Nov 12, 2023 · 10 likes · 1 share · 3,167 followers View post →

All mentions

Vylor
@avgosrs · X

@RhythmDoc01 @IvorEkta @AlecStapp https://t.co/YeAIBJogoI https://t.co/fkFhNVH3Hv https://t.co/rARc6RDM2Q https://t.co/RBABtrugYg Several studies in the last 5 years have linked long-term PPI usage to a massive increase in dementia risk. There's one study and one statement by the american association of

Jun 27, 2025 · 47 followers View post →
Bina Pattel
@BinaPattel · X

33% INCREASE RISK DEVELOPING #DEMENTIA ASSOCIATED WITH LONG–TERM USE OF COMMON ACID REFLUX DRUG – NEW STUDY https://t.co/B0MpYbysA3 40% UK POPULATION EXPERIENCE REGULAR HEARTBURN MEDICATION PREVIOUSLY LINK HIGHER RISK STROKE BROKEN BONES KIDNEY #DISEASE https://t.co/l90InCOzj2

May 2, 2025 · 35 followers View post →
Joyful Heart Health Care
@KetoNurses · X

While PPI meds might relieve SYMPTOMS, they do not resolve the real problem. They act only as a bandaid - hiding the problem - and causing terrible side effects along the way. https://t.co/ONvcL6km4p https://t.co/i5zN24Qj83

Feb 26, 2025 · 918 followers View post →
Joyful Heart Health Care
@KetoNurses · X

While PPI meds might relieve SYMPTOMS, they do not resolve the real problem. They act only as a bandaid - hiding the problem - and causing terrible side effects along the way. https://t.co/ONvcL6km4p https://t.co/kNLQVgWr5W

Jan 27, 2025 · 918 followers View post →
Dr. Ammous
@AmmousMD · X

https://t.co/4ap8fKFmxG https://t.co/uTsJ2n4iw9 https://t.co/UWJIpV7L27 https://t.co/0yKPnTGgFA -"Why stomach acid is good for you" Book. https://t.co/h1LF4LlAOE

Oct 28, 2024 · 3 likes · 10,831 followers View post →
Dana Parish
@danaparish · X

Nope. https://t.co/eTC3GtbTVE

Aug 7, 2024 · 2 likes · 41,081 followers View post →
Ljung&Reimers
@drugs_cognition · X

@DuthieAlyne And it's not only psychiatric drugs. A lot of drug classes can induce cognitive impairment and/or increase the risk of dementia, e.g., heartburn drugs (PPIs). Tens of millions are taking them year in, year out. https://t.co/zLlm1tiGcm

Jul 28, 2024 · 2 followers View post →
Roland Baker
@RolandBakerIII · X

@StevenMathern I wonder about causality here. I mean if you need to take PPIs for over five years why is that when other's don't? Chronic alcoholism? Really poor diet? etc. https://t.co/AlVOf6Km0a

Jul 15, 2024 · 1 like · 8,160 followers View post →
Cristina AC
@Cristin51664286 · X

RT @primastcar: Vía @Montecoya

Jul 14, 2024 · 2 shares · 11 followers View post →
Primastcar
@primastcar · X

Vía @Montecoya

Jul 13, 2024 · 1 like · 2 shares · 2,337 followers View post →
Trung Nguyen
@drtrungnguyen · X

RT @Montecoya: Cumulative Use of Proton Pump Inhibitors and Risk of Dementia | Neurology "Quienes tomaron IPP duante >4.4 años acumulados…

Jul 7, 2024 · 17 shares · 1,394 followers View post →
fidel sobrino mejia
@fesobrinom · X

RT @Montecoya: Cumulative Use of Proton Pump Inhibitors and Risk of Dementia | Neurology "Quienes tomaron IPP duante >4.4 años acumulados…

Jul 7, 2024 · 17 shares · 32 followers View post →
Pablo Perez Solís
@soysolisu · X

RT @Montecoya: Cumulative Use of Proton Pump Inhibitors and Risk of Dementia | Neurology "Quienes tomaron IPP duante >4.4 años acumulados…

Jul 7, 2024 · 17 shares · 1,651 followers View post →
Vcrp
@VirginiaVcrp · X

RT @Montecoya: Cumulative Use of Proton Pump Inhibitors and Risk of Dementia | Neurology "Quienes tomaron IPP duante >4.4 años acumulados…

Jul 7, 2024 · 17 shares · 52 followers View post →
Jose Joaquin Bande
@JJBande · X

RT @Montecoya: Cumulative Use of Proton Pump Inhibitors and Risk of Dementia | Neurology "Quienes tomaron IPP duante >4.4 años acumulados…

Jul 7, 2024 · 17 shares · 115 followers View post →
Yeray Aguilar
@YerayAguilar · X

RT @Montecoya: Cumulative Use of Proton Pump Inhibitors and Risk of Dementia | Neurology "Quienes tomaron IPP duante >4.4 años acumulados…

Jul 7, 2024 · 17 shares · 1,827 followers View post →
Jose
@Jose82044721745 · X

RT @Montecoya: Cumulative Use of Proton Pump Inhibitors and Risk of Dementia | Neurology "Quienes tomaron IPP duante >4.4 años acumulados…

Jul 7, 2024 · 17 shares · 547 followers View post →
Mar Riera Pagespetit
@mar_petit · X

RT @Montecoya: Cumulative Use of Proton Pump Inhibitors and Risk of Dementia | Neurology "Quienes tomaron IPP duante >4.4 años acumulados…

Jul 7, 2024 · 17 shares · 249 followers View post →
Héctor A. L.
@avellonlianno · X

RT @Montecoya: Cumulative Use of Proton Pump Inhibitors and Risk of Dementia | Neurology "Quienes tomaron IPP duante >4.4 años acumulados…

Jul 7, 2024 · 17 shares · 701 followers View post →
Pedro Núñez
@nunyez_ · X

RT @Montecoya: Cumulative Use of Proton Pump Inhibitors and Risk of Dementia | Neurology "Quienes tomaron IPP duante >4.4 años acumulados…

Jul 7, 2024 · 17 shares · 63 followers View post →
Fidel Sobrino
@fidel_sobrino · X

RT @Montecoya: Cumulative Use of Proton Pump Inhibitors and Risk of Dementia | Neurology "Quienes tomaron IPP duante >4.4 años acumulados…

Jul 7, 2024 · 17 shares · 412 followers View post →
JORGE GARCIA
@GeorgusCayo · X

RT @Montecoya: Cumulative Use of Proton Pump Inhibitors and Risk of Dementia | Neurology "Quienes tomaron IPP duante >4.4 años acumulados…

Jul 7, 2024 · 17 shares · 752 followers View post →
Ángel Aledo-Serrano
@AledoNeuro · X

RT @Montecoya: Cumulative Use of Proton Pump Inhibitors and Risk of Dementia | Neurology "Quienes tomaron IPP duante >4.4 años acumulados…

Jul 7, 2024 · 17 shares · 6,746 followers View post →
A.R. García
@air_garcia · X

RT @FAPsGal: Evaluación asociación entre uso actual & acumulado de #IBP y el riesgo de #demencia incidental en el estudio #ARIC Evidencia…

Jul 7, 2024 · 2 shares · 803 followers View post →
AGUSTINA FERNÁNDEZ
@AgusAgusfar · X

RT @FAPsGal: Evaluación asociación entre uso actual & acumulado de #IBP y el riesgo de #demencia incidental en el estudio #ARIC Evidencia…

Jul 7, 2024 · 2 shares · 560 followers View post →
FAPsGal
@FAPsGal · X

Evaluación asociación entre uso actual & acumulado de #IBP y el riesgo de #demencia incidental en el estudio #ARIC Evidencia de Clase III

Jul 7, 2024 · 1 like · 2 shares · 1,371 followers View post →
Rubén Villa
@rubenve · X

RT @Montecoya: Cumulative Use of Proton Pump Inhibitors and Risk of Dementia | Neurology "Quienes tomaron IPP duante >4.4 años acumulados…

Jul 7, 2024 · 17 shares · 491 followers View post →
José Manuel Flores
@candelaimanol · X

RT @Montecoya: Cumulative Use of Proton Pump Inhibitors and Risk of Dementia | Neurology "Quienes tomaron IPP duante >4.4 años acumulados…

Jul 7, 2024 · 17 shares · 367 followers View post →
I’m Kvothe of Temerant
@m_kvothe · X

RT @Montecoya: Cumulative Use of Proton Pump Inhibitors and Risk of Dementia | Neurology "Quienes tomaron IPP duante >4.4 años acumulados…

Jul 7, 2024 · 17 shares · 79 followers View post →
RICARDO DE DIOS
@DIOSDELVALLE · X

RT @Montecoya: Cumulative Use of Proton Pump Inhibitors and Risk of Dementia | Neurology "Quienes tomaron IPP duante >4.4 años acumulados…

Jul 7, 2024 · 17 shares · 756 followers View post →
Sergio Calleja
@Montecoya · X

Cumulative Use of Proton Pump Inhibitors and Risk of Dementia | Neurology "Quienes tomaron IPP duante >4.4 años acumulados presentaron un riesgo de demencia un 33% mayor durante el seguimiento (HR: 1.3 [95% CI 1.0–1.8]) que quienes no los tomaron" https://t.co/SvW3x2RXdE

Jul 7, 2024 · 24 likes · 17 shares · 5,687 followers View post →
RedRocketMagaMan
@RedRocketMaga · X

@ChuckBarry333 @miamivandynyu @BillAckman So are PPIs like Omeprazole (Prilosec) or pantoprazole (protonix) for extended periods of time. Extremely common drug, even OTC; although you shouldn’t take the OTC one for more than 2 weeks without a doctors appointment https://t.co/igLEhm05DI So what’s your point?

Jun 28, 2024 · 2 likes · 95 followers View post →
やすくん
@yasukun6791 · X

PPIの長期使用が認知症の発症を促すってデータがあるくらいだから、脳に何かしらの影響は与えるんだろうけど、これからの研究結果を待ってみます https://t.co/GThtJI3EXe https://t.co/QHOGdsvTO4

Jun 16, 2024 · 15 likes · 4,910 followers View post →
Pharmica
@pharmicauk · X

Long-term use of proton pump inhibitors (a common active ingredient in acid reflux medication) may contribute to dementia risk, according to a novel study

Apr 11, 2024 · 3,228 followers View post →
ドクターK@眼科医パパ
@doctorK1991 · X

RT @b6Ah3b5EjU44445: PPI(胃酸分泌抑制剤)と認知症との関連についての先行研究では一致した結果は得られていませんが、本研究では、累積で4.4年以上使用した人で使用しなかった人と比べて発症リスクが33%上昇し、その関連性を示唆されました。 https://t…

Jan 5, 2024 · 1 share · 56,099 followers View post →
Dr.ちゃうちゃう先生
@drchauchau · X

PPI(胃酸分泌抑制剤)と認知症との関連についての先行研究では一致した結果は得られていませんが、本研究では、累積で4.4年以上使用した人で使用しなかった人と比べて発症リスクが33%上昇し、その関連性を示唆されました。 https://t.co/W2tjY5RxBG

Jan 5, 2024 · 20 likes · 1 share · 1,796 followers View post →
Dr. Prabhudev M Hiremath MD
@Neuroptimist23 · X

IMHO, PPIs are one of the most abused drugs with total disregard to its side effect profile. Stumbled upon this eye opening paper today. Please go through. https://t.co/ptGhBxREvN #neuroscience, #NeuroTwitter #MedTwitter

Dec 13, 2023 · 2 likes · 1,735 followers View post →
Maurício Lima
@dj_surfista · X

Este estudo fornece evidência de Classe III de que o uso de inibidores da bomba de prótons prescritos por >4,4 anos por indivíduos com 45 anos ou mais está associado a uma maior incidência de demência recém-diagnosticada. https://t.co/ExzBzjIDFT

Nov 12, 2023 · 742 followers View post →
Lynne Saunt
@LynneSaunt · X

RT @DrPalmquist: Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study Cutting carb…

Nov 12, 2023 · 1 share · 851 followers View post →
DrRPalmquist
@DrPalmquist · X

Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study Cutting carb intake helps many with “heartburn.” Why not try that before acid blockers? https://t.co/Gw7PaA14Np

Nov 12, 2023 · 10 likes · 1 share · 3,167 followers View post →
Walid Alkeridy وليد الكريدي
@WalidAlkeridy · X

Cumulative Use of Proton Pump Inhibitors and Risk of Dementia https://t.co/jG7xl8WGvL

Nov 5, 2023 · 3 likes · 1,292 followers View post →
thmonk
@thmonk_pf · X

平均年齢75.4±5.1歳の5,712人を平均5.5年調査したAtherosclerosis Risk in Communities(ARIC)研究において、45歳以上の人が処方されたプロトンポンプ阻害薬を4.4年以上使用することが、新たに診断された認知症の高い発生率(HR=1.3)と関連 #PPI #dementia #papers https://t.co/dqOKjq3eBC

Nov 5, 2023 · 4 likes · 1,633 followers View post →
Isaura R. Penin
@irodriguezpenin · X

Cumulative Use of Proton Pump Inhibitors and Risk of Dementia https://t.co/jSy3Bvygvi

Oct 31, 2023 · 1 like · 624 followers View post →
Yvonne Ramia
@YRamia · X

RT @CamiloSalinasOF: El uso prolongado (>4.4 años) de inhibidores de bomba de protones (p. ej. omeprazol): ⬆️ el riesgo de demencia en adul…

Oct 10, 2023 · 2 shares · 258 followers View post →
まるやま@産婦人内科医
@maruyama0706 · X

RT @samcosamsam: 使うにしてもやっぱりPPIは短期間、、そもそも必要だから使う、必要がなくなれば使用しないの原則に変わりなし… Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The…

Oct 10, 2023 · 1 share · 129 followers View post →
顔薄
@samcosamsam · X

使うにしてもやっぱりPPIは短期間、、そもそも必要だから使う、必要がなくなれば使用しないの原則に変わりなし… Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study https://t.co/28VgjeW9Ze

Oct 10, 2023 · 2 likes · 1 share · 864 followers View post →
Camilo Salinas Ochoa
@DrCamiloSalinas · X

RT @CamiloSalinasOF: El uso prolongado (>4.4 años) de inhibidores de bomba de protones (p. ej. omeprazol): ⬆️ el riesgo de demencia en adul…

Oct 9, 2023 · 2 shares · 11,640 followers View post →
Fundacion Camilo Salinas S⚡️
@CamiloSalinasOF · X

El uso prolongado (>4.4 años) de inhibidores de bomba de protones (p. ej. omeprazol): ⬆️ el riesgo de demencia en adultos mayores (promedio de edad 75.4 años) en un 33-42%

Oct 9, 2023 · 2 likes · 2 shares · 6,702 followers View post →
Alexander Böhm
@marcobrunn.bsky.social · Bluesky

Source: Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study Carin Northuis, Elizabeth Bell, Pamela Lutsey, Kristen M George, Rebecca F. Gottesmann et al Neurology Aug 2023, DOI: 10.1212/WNL.0000000000207747 doi.org/10.1212/WNL....

Sep 27, 2023 · 1 like View post →
ElizabethMuhiaMD
@LilyBlessedDoc · X

Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study - PubMed///❤️

Sep 18, 2023 · 265 followers View post →
みや
@1ch1go1ch1e · X

RT @37phoenix: PPIと認知量リスク。PPI使用者と非使用者で認知症発症リスクに差はなかった。4.4年以上の使用は33%のリスク上昇がみられた。Neurology. PMID: 37558503. https://t.co/Pxjw5CpDYW

Sep 16, 2023 · 2 shares · 3,546 followers View post →
トンヌラ
@37phoenix · X

PPIと認知量リスク。PPI使用者と非使用者で認知症発症リスクに差はなかった。4.4年以上の使用は33%のリスク上昇がみられた。Neurology. PMID: 37558503. https://t.co/Pxjw5CpDYW

Sep 16, 2023 · 28 likes · 2 shares · 2,053 followers View post →
Mahmut Köylü
@mhmtkyll · X

Mide koruyucuların, demans gelistirme riskini %33 oranında arttırdığı ile ilgili bir çalışma. #Neurology #MedTwitter #Pharmacology #neuropharmacology https://t.co/thTId7y6qO

Sep 13, 2023 · 1,047 followers View post →
Mahmut Köylü
@mhmtkyll · X

Mide koruyucuların, demans gelistirme riskini %33 arttırdığı ile ilgili bir çalışma. #Neurology #MedTwitter #Pharmacology #neuropharmacology https://t.co/thTId7y6qO

Sep 13, 2023 · 1,047 followers View post →
ネコ2世 (ヒュージヘモ)
@8xGen3urg · X

RT @thmonk_pf: 4.4年以上のPPI服用歴は将来の認知障害のriskが上昇 Atherosclerosis Risk in Communities (ARIC) Studyの5712人を対象とし追跡期間中央値5.5年で、4.4年以上のPPI服用歴はHR1.3…

Sep 5, 2023 · 3 shares · 213 followers View post →
のぐち
@drtwitting1 · X

Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study.(PMID:37558503) https://t.co/j3GgPhF58f

Sep 5, 2023 · 1,049 followers View post →
Victor Del Bene
@victor_delbene · X

RT @nvillain_alz: Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study https://t.co…

Sep 1, 2023 · 1 share · 2,070 followers View post →
Nicolas Villain / Moved to LinkedIn & BlueSky
@nvillain_alz · X

Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study https://t.co/VnUNQ78rwH

Sep 1, 2023 · 4 likes · 1 share · 982 followers View post →
Nicolas Villain
@nvillain-alz.bsky.social · Bluesky

Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study n.neurology.org/content/early/…

Sep 1, 2023 View post →
田舎もん内科医
@doctor_mk22 · X

PPIの長期内服は認知症のリスクが高まる可能性があるのね。やっぱ漫然と続けたらダメね https://t.co/W9QMeKG3rR

Aug 29, 2023 · 5 likes · 1,547 followers View post →
Patricia Lasseter
@PLasseter · X

Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study - PubMed https://t.co/j4QnNxCOuG

Aug 23, 2023 · 118 followers View post →
Ray Walley
@WalleyRay · X

RT @alvaro_casasher: The use of prescribed PPIs for > 4.4 years by individuals ages 45 years and older is associated with a higher incidenc…

Aug 23, 2023 · 3 shares · 7,490 followers View post →
Alexandre Gérard
@AlexandreGerard · X

Une exposition pendant plus de 4 ans pourrait augmenter le risque de démence Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study https://t.co/Nxzs0pq2Lb

Aug 22, 2023 · 3 likes · 1,339 followers View post →
OM Aguilar, M.D., MPH, FACC, FAHA, CWP
@Omaguilarmd · X

Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: ARIC Study. Neurology Aug 2023. Clear possible consequences of prolonged use of these antiacids. Acidity is key for nitric oxide production and digestion. The microbiota needs be treated instead.

Aug 21, 2023 · 1 like · 96 followers View post →
#hellomynameis Shane
@drohanlon · X

RT @alvaro_casasher: The use of prescribed PPIs for > 4.4 years by individuals ages 45 years and older is associated with a higher incidenc…

Aug 20, 2023 · 3 shares · 3,812 followers View post →
Ignacio Reyes A.
@Reyes_paliativo · X

RT @alvaro_casasher: The use of prescribed PPIs for > 4.4 years by individuals ages 45 years and older is associated with a higher incidenc…

Aug 20, 2023 · 3 shares · 65 followers View post →
Alvaro Casas Herrero
@alvaro_casasher · X

The use of prescribed PPIs for > 4.4 years by individuals ages 45 years and older is associated with a higher incidence of newly diagnosed dementia. https://t.co/5UpBXaDAjF

Aug 20, 2023 · 6 likes · 3 shares · 2,603 followers View post →
Dr. Farrukh MALIK ᴹᴾᴴ ᴾʰᴰ
@malikfj · X

Simply taking a #PPI did not necessarily result in a higher risk, as the key was the amount of time that a person took one of the #medicines . “Cumulative Use of Proton Pump Inhibitors and #Risk of #Dementia” https://t.co/RltCUmAqPW

Aug 19, 2023 · 252 followers View post →
Joel "Heart Prevention" Kahn MD, FACC
@drjkahn · X

Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study https://t.co/ycohKxMm8R

Aug 18, 2023 · 1 like · 32,274 followers View post →
MedChem & ONCo&
@MedChem314 · X

Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study Carin Northuis and al. Neurology August 09, 2023 https://t.co/LYQwwk2OBB

Aug 17, 2023 · 588 followers View post →
elissaleonard
@elissaleonard · X

overmedicated and undernourished: #Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study | Neurology https://t.co/zd6YBGxXJa

Aug 16, 2023 · 409 followers View post →
Wejolyn
@Wejolyn · X

all acid blockers (PPI’s) for the gut- “Cumulative Use of Proton Pump Inhibitors and Risk of Dementia..” get to root cause instead-fix your gut! https://t.co/KW4DlpTyif

Aug 16, 2023 · 4 likes · 17,989 followers View post →
UMN Cerebrovascular & Neurocritical Care
@umnstrokencc · X

Congrats to Dr. Lakshminarayan and team on their publication: Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study https://t.co/4DNrFYbcvX

Aug 16, 2023 · 1 like · 760 followers View post →
Walid Alkeridy وليد الكريدي
@WalidAlkeridy · X

Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study https://t.co/c2Jj7OrQ7r

Aug 15, 2023 · 2 likes · 1,292 followers View post →
frLarousse2
@frLarousse2 · X

RT @dr_cottrell: Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study https://t.co/…

Aug 14, 2023 · 1 share · 2,857 followers View post →
SEREFNUR OZTURK
@SEREFNUROZTURK · X

Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study https://t.co/NuItW5vbYo

Aug 14, 2023 · 1,227 followers View post →
mom
@mom_neurosci · X

RT @thmonk_pf: 4.4年以上のPPI服用歴は将来の認知障害のriskが上昇 Atherosclerosis Risk in Communities (ARIC) Studyの5712人を対象とし追跡期間中央値5.5年で、4.4年以上のPPI服用歴はHR1.3…

Aug 14, 2023 · 3 shares · 809 followers View post →
thmonk
@thmonk_pf · X

4.4年以上のPPI服用歴は将来の認知障害のriskが上昇 Atherosclerosis Risk in Communities (ARIC) Studyの5712人を対象とし追跡期間中央値5.5年で、4.4年以上のPPI服用歴はHR1.3 議論になっているPPIについて今回はクロという報告 Open Access #PPI #dementia #papers https://t.co/dqOKjq3eBC

Aug 13, 2023 · 10 likes · 3 shares · 1,633 followers View post →
Satoru Mitsuboshi
@3stars67664378 · X

RT @pinacol: 【観察研究】ARIC研究参加者において、訪問5回目前に累積4.4年を超えてPPIを使用していた参加者は、不使用の参加者と比較して、追跡期間中の認知症発症リスク増加と関連した。 #ペ読 https://t.co/5fKodZnof2

Aug 13, 2023 · 1 share · 1,784 followers View post →
pinacol
@pinacol · X

【観察研究】ARIC研究参加者において、訪問5回目前に累積4.4年を超えてPPIを使用していた参加者は、不使用の参加者と比較して、追跡期間中の認知症発症リスク増加と関連した。 #ペ読 https://t.co/5fKodZnof2

Aug 12, 2023 · 1 like · 1 share · 1,616 followers View post →
Robert Olney
@boretrol · X

Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study https://t.co/V8fjfPUXi1

Aug 11, 2023 · 2 likes · 1,671 followers View post →
Ruslan Dorfman
@RuslanDorfman · X

Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study https://t.co/aFGVsdNjbo this is yet another study that confirms the increased risk of dementia in long term PPI users https://t.co/mBeqzFPXos

Aug 11, 2023 · 1,014 followers View post →
Bam-bam
@cesar_ivan88 · X

RT @CAlejandroneuro: ⚠️ Usuarios acumulados de IBP a largo plazo tenían un 33% más de riesgo de desarrollar demencia en una etapa avanzada…

Aug 11, 2023 · 1 share · 1,979 followers View post →
サイエンスあれこれ
@sarekore · X

ない人に比べて、認知症のリスクが33%高い可能性があることがわかりました。薬の服用期間が4年半未満の人ではリスクの上昇は認められませんでした。これまでの研究ではプロトンポンプ阻害剤の長期使用は脳卒中、骨折、慢性腎臓病のリスクの増加と関連付けられていました。https://t.co/3SfC0CxEDz

Aug 11, 2023 · 1 share · 922 followers View post →
Sergey Minaev
@sminaev2015 · X

Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study | Neurology https://t.co/gYma3VmylO

Aug 11, 2023 · 4 likes · 31,475 followers View post →
Claudio Alejandro
@CAlejandroneuro · X

⚠️ Usuarios acumulados de IBP a largo plazo tenían un 33% más de riesgo de desarrollar demencia en una etapa avanzada de la vida ✅Obviamente es 1 estudio, pero es una alerta! "nos parecería considerar mejor ese Omeprazol eterno???..." DOI: 10.1212/WNL.0000000000207747

Aug 10, 2023 · 7 likes · 1 share · 4,872 followers View post →
安西英雄
@deoanzai · X

プロトンポンプ阻害剤を4.4年以上飲んでた人は痴呆を発症するリスクが33%も高いそうだ。ときどきこの話出るよね。 Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study https://t.co/bcDIluQpnI

Aug 10, 2023 · 3 likes · 866 followers View post →
Dr. Paul Cottrell
@dr_cottrell · X

Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study https://t.co/nEdNUmlBaE

Aug 10, 2023 · 11 likes · 1 share · 10,331 followers View post →
The Colitist
@colitist · X

Cumulative Use of Proton Pump Inhibitors and Risk of Dementia: The Atherosclerosis Risk in Communities Study https://t.co/1u3j3LQw6J

Aug 9, 2023 · 316 followers View post →