Attention Deficit Hyperactivity Disorder (ADHD) and the gut microbiome: An ecological perspective.

Abstract in brief

• The review explores how the gut microbiome, which involves complex interactions among microorganisms and neurotransmitter pathways, may influence ADHD symptoms like hyperactivity and impulsivity, by examining microbial relationships beyond simple abundance measures.
• Researchers analyze gut microbiome data from an ADHD study using traditional metrics like diversity and differential abundance, then advance to ecological network analysis to understand cooperation and competition among microbial taxa, aiming to uncover deeper insights into microbiome dynamics in ADHD.
• The study employs co-occurrence network models and community detection to identify key microbial clusters and influential taxa, providing a more detailed ecological perspective that could help clarify inconsistent findings in previous research on the microbiome's role in ADHD.