J Intern Med January 2024 PMID 37614046

Replacing device-measured sedentary time with physical activity is associated with lower risk of coronary heart disease regardless of genetic risk.

Youngwon Kim, Haeyoon Jang, Mengyao Wang, Qiaoxin Shi, Tessa Strain, Stephen J Sharp, Shiu Lun Au Yeung, Shan Luo, Simon Griffin, Nicholas J Wareham, Katrien Wijndaele, Soren Brage

Mentions

31
Peak: 5 in Aug 2023
across 5 sources since Aug 2023

Extended reach

22,023
potential audience

Total likes

46

Video views

669

Mentions per month

Aug 2023 – May 2025

Where it's discussed

  • X / Twitter15 posts
  • News9 articles
  • Blogs3 articles
  • YouTube2 videos
  • Facebook2 posts

AI synopsis

What people are saying

The collective responses demonstrate strong agreement and interest, with examples such as mentions of studies showing even small changes (as little as 1 minute per day) can reduce heart disease risk. The tone and context reveal a focus on both scientific evidence and practical health advice, emphasizing the importance of behavioral shifts.

AgreementStrong agreement

Most discussions strongly support the idea that replacing sedentary behavior with physical activity lowers the risk of heart disease, emphasizing consensus on the publication's findings.

InterestHigh interest

The pervasive sharing and highlighting of specific research details suggest high curiosity and engagement with the topic.

EngagementModerate engagement

Posts reference studies, specific metrics, and implications, indicating a moderate level of deep engagement with the research details.

ImpactHigh impact

Multiple discussions underscore the significant health implications and potential for behavioral change, pointing to high perceived impact.

Abstract in brief

  • Replacing device-measured sedentary time with physical activity is linked to a lower risk of coronary heart disease, regardless of genetic risk factors.
  • Engaging in more moderate-to-vigorous physical activity (MVPA) by reallocating 60 minutes of sedentary time can reduce CHD risk by about 9%, with greater absolute benefits observed in those with higher genetic susceptibility.
  • The study found no significant interaction between genetic risk and sedentary behavior, meaning that increasing physical activity benefits all groups equally, but those at higher genetic risk experience larger absolute risk reductions.]

Top posts

Most liked on X and Bluesky
INTUE
@INTUE_ · X

Replacing device-measured sedentary time with physical activity is associated with lower risk of coronary heart disease regardless of genetic risk Youngwon Kim et al. https://t.co/97u0VcQBED

Nov 20, 2023 · 13 likes · 4 shares · 494 followers View post →
IppeiChiba
@ptIchiba · X

座位時間60分をMVPAに置き換えにより遺伝リスクによらず冠動脈疾患のリスクが9%減。 LPAへの置き換えではリスク低下を示さず。 実際には座位時間をまるまるMVPAってわけにはいかないと思うので、例えばLPAとMVPA半々みたいな現実に沿った分析ってできないのかな? https://t.co/SO82Qenp1z

Dec 13, 2023 · 7 likes · 231 followers View post →
Rei Ono
@Kobe_ROno · X

座位時間を中等度以上に運動への置き換えは、遺伝的リスクが高くてもCHD発症を抑えるのか? Replacing device-measured sedentary time with physical activity is associated with lower risk of coronary heart disease regardless of genetic risk https://t.co/ZmNlHv1Zyt

Feb 28, 2024 · 5 likes · 1 share · 1,027 followers View post →
HKU Public Health
@HKU_SPH · X

An #HKUSPH study finds replacing any amount of wearable-device-measured sedentary time (as little as 1 min/day) w/ same amount of moderate-to-vigorous #physicalactivity is associated w/ #coronaryheartdisease risk, regardless of genetic risk. Read paper: https://t.co/UwHOkokrCU https://t.co/DaoDM0OPnt

Aug 28, 2023 · 4 likes · 1,923 followers View post →
MRC Epidemiology Unit
@MRC_Epid · X

New @JInternMed paper finds that replacing any amount of #sedentary time with an equal amount of moderate-to-vigorous #PhysicalActivity time is associated with ⬇️ risk of coronary #heartdisease (CHD), irrespective of genetic susceptibility to CHD. https://t.co/0Q6X6GsWy3 https://t.co/fEIry743ES

Aug 31, 2023 · 3 likes · 3 shares · 6,071 followers View post →
JIM - Journal of Internal Medicine
@JInternMed · X

New article! Replacing sedentary time (any amount, from as little as 1 minute/day) with the same amount of moderate-to-vigorous physical activity is associated with lower coronary heart disease risk, regardless of genetic risk. Read more: https://t.co/6PU2ia3Hr0 @HKU_SPH https://t.co/AfZdyroGol

Aug 24, 2023 · 3 likes · 1,642 followers View post →

All mentions

IppeiChiba
@ptIchiba · X

RT @Kobe_ROno: 座位時間を中等度以上に運動への置き換えは、遺伝的リスクが高くてもCHD発症を抑えるのか? Replacing device-measured sedentary time with physical activity is associated…

Feb 28, 2024 · 1 share · 231 followers View post →
Rei Ono
@Kobe_ROno · X

座位時間を中等度以上に運動への置き換えは、遺伝的リスクが高くてもCHD発症を抑えるのか? Replacing device-measured sedentary time with physical activity is associated with lower risk of coronary heart disease regardless of genetic risk https://t.co/ZmNlHv1Zyt

Feb 28, 2024 · 5 likes · 1 share · 1,027 followers View post →
Alessio Bricca
@a_bricca · X

But whether replacing sedentary time with physical activity benefits CHD prevention to a greater degree in individuals at high genetic risk of CHD compared with those at low genetic risk of CHD is unknown. https://t.co/tMIAHr3sHW

Feb 27, 2024 · 3,625 followers View post →
IppeiChiba
@ptIchiba · X

座位時間60分をMVPAに置き換えにより遺伝リスクによらず冠動脈疾患のリスクが9%減。 LPAへの置き換えではリスク低下を示さず。 実際には座位時間をまるまるMVPAってわけにはいかないと思うので、例えばLPAとMVPA半々みたいな現実に沿った分析ってできないのかな? https://t.co/SO82Qenp1z

Dec 13, 2023 · 7 likes · 231 followers View post →
Patrick Kwame Akwaboah
@kwame_akwaboa · X

RT @INTUE_: Replacing device-measured sedentary time with physical activity is associated with lower risk of coronary heart disease regardl…

Nov 23, 2023 · 4 shares · 63 followers View post →
Active Living & Public Health
@actively4health · X

RT @INTUE_: Replacing device-measured sedentary time with physical activity is associated with lower risk of coronary heart disease regardl…

Nov 21, 2023 · 4 shares · 518 followers View post →
Sedentary Behaviour Research Network
@SedBehaviourRN · X

RT @INTUE_: Replacing device-measured sedentary time with physical activity is associated with lower risk of coronary heart disease regardl…

Nov 21, 2023 · 4 shares · 2,393 followers View post →
Aleš Gába
@alesgaba · X

RT @INTUE_: Replacing device-measured sedentary time with physical activity is associated with lower risk of coronary heart disease regardl…

Nov 21, 2023 · 4 shares · 460 followers View post →
INTUE
@INTUE_ · X

Replacing device-measured sedentary time with physical activity is associated with lower risk of coronary heart disease regardless of genetic risk Youngwon Kim et al. https://t.co/97u0VcQBED

Nov 20, 2023 · 13 likes · 4 shares · 494 followers View post →
JIM - Journal of Internal Medicine
@JInternMed · X

RT @MRC_Epid: New @JInternMed paper finds that replacing any amount of #sedentary time with an equal amount of moderate-to-vigorous #Physic…

Sep 2, 2023 · 3 shares · 1,642 followers View post →
Rod FK
@RodFK01 · X

RT @MRC_Epid: New @JInternMed paper finds that replacing any amount of #sedentary time with an equal amount of moderate-to-vigorous #Physic…

Aug 31, 2023 · 3 shares · 217 followers View post →
Ryan Au Yeung
@Ryan_Au_Yeung · X

RT @MRC_Epid: New @JInternMed paper finds that replacing any amount of #sedentary time with an equal amount of moderate-to-vigorous #Physic…

Aug 31, 2023 · 3 shares · 750 followers View post →
MRC Epidemiology Unit
@MRC_Epid · X

New @JInternMed paper finds that replacing any amount of #sedentary time with an equal amount of moderate-to-vigorous #PhysicalActivity time is associated with ⬇️ risk of coronary #heartdisease (CHD), irrespective of genetic susceptibility to CHD. https://t.co/0Q6X6GsWy3 https://t.co/fEIry743ES

Aug 31, 2023 · 3 likes · 3 shares · 6,071 followers View post →
HKU Public Health
@HKU_SPH · X

An #HKUSPH study finds replacing any amount of wearable-device-measured sedentary time (as little as 1 min/day) w/ same amount of moderate-to-vigorous #physicalactivity is associated w/ #coronaryheartdisease risk, regardless of genetic risk. Read paper: https://t.co/UwHOkokrCU https://t.co/DaoDM0OPnt

Aug 28, 2023 · 4 likes · 1,923 followers View post →
JIM - Journal of Internal Medicine
@JInternMed · X

New article! Replacing sedentary time (any amount, from as little as 1 minute/day) with the same amount of moderate-to-vigorous physical activity is associated with lower coronary heart disease risk, regardless of genetic risk. Read more: https://t.co/6PU2ia3Hr0 @HKU_SPH https://t.co/AfZdyroGol

Aug 24, 2023 · 3 likes · 1,642 followers View post →