January 2024 PMID 37615485

Adding fasting-mimicking diet to first-line carboplatin-based chemotherapy is associated with better overall survival in advanced triple-negative breast cancer patients: A subanalysis of the NCT03340935 trial.

Francesca Ligorio, Riccardo Lobefaro, Giovanni Fucà, Leonardo Provenzano, Lucrezia Zanenga, Vincenzo Nasca, Caterina Sposetti, Giulia Salvadori, Angela Ficchì, Andrea Franza, Antonia Martinetti, Elisa Sottotetti, Barbara Formisano, Catherine Depretto, Gianfranco Scaperrotta

Mentions

13
Peak: 4 in Aug 2023
across 3 sources since Aug 2023

Extended reach

192,501
potential audience

Total likes

7,982

Video views

152,304

Mentions per month

Aug 2023 – Sep 2025

Where it's discussed

  • X / Twitter10 posts
  • YouTube2 videos
  • Bluesky1 posts

AI synopsis

What people are saying

The discussions consistently show support for the article's findings, with posts highlighting improved survival outcomes, such as 'Patients with #aTNBC receiving chemotherapy plus fasting-mimicking diet had better overall survival,' indicating strong agreement. The tone is enthusiastic yet informational, driven by phrases like 'supercharges your Body' and calls to attention during Breast Cancer Awareness Month, reflecting high interest, but limited technical engagement beyond sharing key results, which results in moderate impact overall.

AgreementModerate agreement

Most discussions acknowledge and support the positive findings of the study, emphasizing the improved survival with the diet intervention.

InterestHigh interest

The topic of integrating dietary strategies into cancer treatment appears highly relevant and engaging for audiences interested in biomedical advances.

EngagementModerate engagement

Posts are somewhat superficial, mostly sharing headlines or calls to check out the study, with limited deep analysis or critique.

ImpactModerate impact

The discussions highlight potential clinical importance, but overall, the influence is primarily awareness-raising rather than advocating immediate change.

Abstract in brief

  • Severe calorie restriction through cyclic fasting or fasting-mimicking diets (FMDs) enhances the effectiveness of chemotherapy in treating triple-negative breast cancer (TNBC) in mice by lowering glucose levels and improving immune response.
  • Clinical data shows that TNBC patients receiving both chemotherapy and cyclic FMD experienced better overall survival (OS) compared to those on chemotherapy alone, with a median OS of 30.3 months versus 17.2 months.
  • The results suggest that incorporating cyclic FMD with chemotherapy could improve outcomes for advanced TNBC patients, indicating a potential for further research in clinical trials to explore its effectiveness in earlier-stage cases as well.

Top posts

Most liked on X and Bluesky
Caterina Sposetti, MD
@CateSposetti · X

Curious about the impact of metabolic interventions on survival of patients with advanced triple-negative breast cancer? Check out our article, led by

Aug 25, 2023 · 12 likes · 6 shares · 710 followers View post →
International Journal of Cancer
@IntJCanc · X

October is #BreastCancerAwarenessMonth! Patients with #aTNBC receiving chemotherapy plus fasting-mimicking diet had better overall survival when compared to patients treated with chemotherapy alone

Oct 2, 2023 · 2 likes · 2 shares · 1,788 followers View post →
thatamerican.bsky.social
@thatamerican.bsky.social · Bluesky

youtu.be/phg_9Vv22fk?... Pay Attention...

Aug 28, 2025 · 1 like · 1 share View post →
Matteo Lambertini, MD PhD
@matteolambe · X

RT @CaterinaSpo: Curious about the impact of metabolic interventions on survival of patients with advanced triple-negative breast cancer? C…

Aug 25, 2023 · 6 shares · 17,984 followers View post →
Wiley Clinical Health
@WileyHealth · X

RT @IntJCanc: October is #BreastCancerAwarenessMonth! Patients with #aTNBC receiving chemotherapy plus fasting-mimicking diet had better o…

Oct 2, 2023 · 2 shares · 11,924 followers View post →
Jeffrey Jones
@jeffreyjones · X

In just days, this Nutrition Protocol supercharges your Body to destroy ... https://t.co/3YcxFO9iSZ via @YouTube

Sep 25, 2025 · 3,243 followers View post →

All mentions

Ravick Bitencourt
@Ravick_BlueLion · X

https://t.co/OnAQkcdHq1

Sep 29, 2025 · 166 followers View post →
Jeffrey Jones
@jeffreyjones · X

In just days, this Nutrition Protocol supercharges your Body to destroy ... https://t.co/3YcxFO9iSZ via @YouTube

Sep 25, 2025 · 3,243 followers View post →
Ali Rashed alzaabi
@il0veUAE · X

In just days, this Nutrition Protocol supercharges your Body to destroy ... https://t.co/xJd6QHo2Xw via @YouTube

Sep 19, 2025 · 135 followers View post →
thatamerican.bsky.social
@thatamerican.bsky.social · Bluesky

youtu.be/phg_9Vv22fk?... Pay Attention...

Aug 28, 2025 · 1 like · 1 share View post →
Wiley Oncology & Hematology
@WileyOnc_Hem · X

RT @IntJCanc: October is #BreastCancerAwarenessMonth! Patients with #aTNBC receiving chemotherapy plus fasting-mimicking diet had better o…

Oct 2, 2023 · 2 shares · 2,179 followers View post →
Wiley Clinical Health
@WileyHealth · X

RT @IntJCanc: October is #BreastCancerAwarenessMonth! Patients with #aTNBC receiving chemotherapy plus fasting-mimicking diet had better o…

Oct 2, 2023 · 2 shares · 11,924 followers View post →
International Journal of Cancer
@IntJCanc · X

October is #BreastCancerAwarenessMonth! Patients with #aTNBC receiving chemotherapy plus fasting-mimicking diet had better overall survival when compared to patients treated with chemotherapy alone

Oct 2, 2023 · 2 likes · 2 shares · 1,788 followers View post →
Living with Lobular Breast Cancer in Canada
@lobbccanada · X

RT @CaterinaSpo: Curious about the impact of metabolic interventions on survival of patients with advanced triple-negative breast cancer? C…

Aug 25, 2023 · 6 shares · 754 followers View post →
Matteo Lambertini, MD PhD
@matteolambe · X

RT @CaterinaSpo: Curious about the impact of metabolic interventions on survival of patients with advanced triple-negative breast cancer? C…

Aug 25, 2023 · 6 shares · 17,984 followers View post →
Federico Nichetti
@fedenichetti · X

RT @CaterinaSpo: Curious about the impact of metabolic interventions on survival of patients with advanced triple-negative breast cancer? C…

Aug 25, 2023 · 6 shares · 1,253 followers View post →
Caterina Sposetti, MD
@CateSposetti · X

Curious about the impact of metabolic interventions on survival of patients with advanced triple-negative breast cancer? Check out our article, led by

Aug 25, 2023 · 12 likes · 6 shares · 710 followers View post →