Adv Nutr November 2023 PMID 37619764

The Safety and Antiaging Effects of Nicotinamide Mononucleotide in Human Clinical Trials: an Update.

Qin Song, Xiaofeng Zhou, Kexin Xu, Sishi Liu, Xinqiang Zhu, Jun Yang

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Peak: 6 in Dec 2023

across 4 sources since Aug 2023

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34,909

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Aug 2023 – Sep 2025

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AI synopsis

What people are saying

The discussions display a positive attitude towards the research, with comments highlighting personal use 'sehnali jsme velmi kvalitní tady' (we found very good here) and references to broader themes like longevity and rejuvenation. The tone is optimistic but not overly technical, emphasizing potential benefits and current interest in supplement use, thereby supporting a moderate to high collective interest and positive perception of the research's significance.

AgreementModerate agreement

Most discussions acknowledge the positive potential of NMN in antiaging and health, reflecting general scientific optimism.

InterestHigh interest

Participants are highly interested, with many explicitly mentioning themes like longevity, healthspan, and rejuvenation, indicating strong engagement.

EngagementModerate engagement

While some posts share personal experiences or enthusiasm, few delve deeply into scientific details, showing moderate engagement.

ImpactModerate impact

The discussions suggest that the article influences opinions on health and aging, though broader societal or clinical impact remains moderate.

Abstract in brief

Nicotinamide mononucleotide (NMN) is a precursor to NAD, a molecule essential for various bodily functions, and its levels tend to decrease with age, which may contribute to aging and related diseases.
Studies in cells and animals suggest that NMN supplementation can boost NAD levels and potentially slow down aging processes by reducing oxidative stress, DNA damage, and inflammation, but human data is limited.
Currently, about a dozen clinical trials are exploring NMN's safety and effectiveness in humans, and ongoing research aims to better understand its health benefits and guide future applications.]

Read the full abstract

All mentions

Exploring Longevity: Supplements, Drug Repurposing, and CR Insights

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Dr. Laurena Law · May 28, 2025 2,025 views

Comparing NMN and NR Supplements for Healthy Aging

This video explores the growing interest in NMN and NR supplements and their potential benefits. Focused on scientific findings, it examines which supplement may be more effective for boosting NAD levels and the…

nuo life - Longevity · Aug 8, 2024 1,763 views

Nicotinamide Mononucleotide NMN: Anti-Aging Benefits and Safety Review

Nicotinamide mononucleotide NMN has gained attention for its potential to promote longevity and reduce age-related health issues. While preliminary studies are promising, more clinical trials are needed to confirm its…

Science · Jan 26, 2024 369 views

サイエンスあれこれ

@sarekore · X

観察された改善や保護効果は、ヒトの臨床試験ではほとんど見られませんでした。https://t.co/Zf0FhxI5JC

Sep 8, 2025 · 2 likes · 922 followers View post →

jomarie

@jomariexx · X

https://t.co/eVLnOOzZD4 The Safety and Antiaging Effects of Nicotinamide Mononucleotide in Human Clinical Trials: an Update== NIH National Library of Medicine https://t.co/1rfcMSiIAW

Nov 23, 2024 · 356 followers View post →

Brain We Are

@brain_we · X

Jan 30, 2024 · 6 likes · 3,356 followers View post →

STAKING LAND

@stakingland · X