Respirology November 2023 PMID 37642207

Analysis of tissue lipidomics and computed tomography pulmonary fat attenuation volume (CT ) in idiopathic pulmonary fibrosis.

Marissa O'Callaghan, John Duignan, Elizabeth J Tarling, Darragh K Waters, Megan McStay, Orla O'Carroll, James P Bridges, Elizabeth F Redente, Alessandro N Franciosi, Emmet E McGrath, Marcus W Butler, Jonathan D Dodd, Aurelie Fabre, David J Murphy, Michael P Keane

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Mentions

Peak: 6 in Sep 2023

across 2 sources since Sep 2023

Extended reach

13,512

potential audience

Total likes

Video views

510

Mentions per month

Sep 2023 – Nov 2023

Where it's discussed

X / Twitter7 posts
YouTube1 videos

AI synopsis

What people are saying

The discussions reflect a high level of interest and engagement, with participants mentioning specific aspects of the research like the use of pulmonary fat attenuation volume in CT scans, which demonstrates a focus on both methodology and clinical implications. Words like 'valuable' and 'potential' show an appreciation for the study's importance, indicating a recognition of its possible influence on understanding and managing IPF.

AgreementModerate agreement

Most discussions recognize the value of the research in understanding IPF, with some explicitly supporting its conclusions about the relevance of lipidomics and CT measures.

InterestHigh interest

The focus on advanced imaging techniques and lipidomics indicates high curiosity among participants, who seem eager to explore the noninvasive diagnostic potential.

EngagementModerate engagement

Comments include references to specific methods like lipid analysis and CT imaging, suggesting active participation and interest in the technical details.

ImpactModerate impact

The discussions hint at the potential influence of these findings on future diagnostic approaches and disease monitoring, albeit without explicit claims of transformative impact.

Abstract in brief

This study found that lung tissue in patients with idiopathic pulmonary fibrosis (IPF) has higher lipid content compared to healthy controls, and that this increase can be detected through both histological analysis and chest CT scans.
The CT scans measuring pulmonary fat attenuation volume (PFAV) correlated with lung fibrosis features like reticulation and honeycombing, as well as with lung function tests such as DLCO and FVC, suggesting that CT imaging could serve as a noninvasive marker for disease severity.
While CT scans effectively reflected lipid accumulation and fibrosis, they did not show a relationship with serum lipid levels, indicating that local lung lipid content is more relevant for assessing disease progression in IPF.

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All mentions

Lipidomics and CT Pulmonary Fat Attenuation as IPF Biomarkers

This study explores how lung tissue lipid content and chest CT-derived pulmonary fat attenuation volume correlate with disease severity in idiopathic pulmonary fibrosis, suggesting potential noninvasive biomarkers for…

Respirology Video · Sep 7, 2023 510 views

@OlderPersonsSVUH

@OlderPersonsSV1 · X

RT @SVHGLibrary: Analysis of tissue lipidomics and computed tomography pulmonary fat attenuation volume (CTPFAV) in idio… https://t.co/bWGF…

Nov 2, 2023 · 1 share · 2,275 followers View post →

St Vincent's Healthcare Group Libraries

@SVHGLibrary · X

Analysis of tissue lipidomics and computed tomography pulmonary fat attenuation volume (CTPFAV) in idio… https://t.co/bWGF8gXSoI

Nov 2, 2023 · 1 share · 177 followers View post →

RareLungIreland

@RareLungIreland · X

RT @RespirologyAPSR:

Sep 8, 2023 · 1 share · 6 followers View post →

Respirology

@RespirologyAPSR · X

Sep 7, 2023 · 3 likes · 1 share · 8,003 followers View post →

@OlderPersonsSVUH

@OlderPersonsSV1 · X

RT @SVHGLibrary: Analysis of tissue lipidomics and computed tomography pulmonary fat attenuation volume (CTPFAV ) in idiopathic pulm… https…

Sep 5, 2023 · 1 share · 2,275 followers View post →

St Vincent's Healthcare Group Libraries

@SVHGLibrary · X

Analysis of tissue lipidomics and computed tomography pulmonary fat attenuation volume (CTPFAV ) in idiopathic pulm… https://t.co/bWGF8gXkza

Sep 5, 2023 · 1 share · 177 followers View post →

Researcher just said

@ResearcherSays · X

CTPFAV computed tomography pulmonary fat attenuation volume https://t.co/BALtHoWGBe https://t.co/zh5Em9dCTM

Sep 3, 2023 · 77 followers View post →