Cell Stem Cell September 2023 PMID 37683604

Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation.

Jiaowei Wang, Wenguang Xie, Nan Li, Wenjuan Li, Zhishuai Zhang, Nana Fan, Zhen Ouyang, Yu Zhao, Chengdan Lai, Hao Li, Mengqi Chen, Longquan Quan, Yunpan Li, Yu Jiang, Wenqi Jia

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Mentions

483

Peak: 45 in Sep 2023

across 6 sources since Sep 2023

Extended reach

762,708

potential audience

Total likes

3,497

Video views

282,621

Mentions per month

Sep 2023 – Oct 2024

Where it's discussed

News410 articles
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Blogs15 articles
YouTube3 videos
Facebook2 posts
Reddit2 posts

AI synopsis

What people are saying

Overall, the discussions display strong support and enthusiasm, especially with posts that translate technical titles into accessible language, like 'Scientists grow humanized kidneys in pig embryos.' The tone and word choices emphasize the groundbreaking nature and potential societal impact of this research, such as overcoming organ shortages and advancing regenerative medicine.

AgreementModerate agreement

Most discussions reflect support and excitement for the scientific advancement, emphasizing its potential to address organ shortages.

InterestHigh interest

The topic clearly attracts high interest, with many posts highlighting the significance of growing human organs in pigs.

EngagementHigh engagement

Users engage deeply by summarizing the research, discussing its implications, and sharing examples like 'growing human kidneys in pig embryos' and 'organ donation solutions'.

ImpactHigh impact

The discussions suggest this research could have a high impact on regenerative medicine and transplantation, with phrases like 'world's first' and references to solving organ shortages.

Abstract in brief

Heterologous organ transplantation is a promising technique to replace organ functions but struggles with a severe shortage of available organs.
Researchers aimed to enhance human cell integration in pig embryos by improving stem cell culture conditions and overexpressing two pro-survival genes, resulting in increased cell viability.
This led to the successful development of human-pig chimeric kidney structures, marking a significant step toward creating humanized organs for regenerative medicine and studying kidney development.

Read the full abstract

All mentions

Human Pluripotent Stem Cells in Monkey Embryos for Regenerative Medicine

This study explores the potential of human extended pluripotent stem cells in cynomolgus monkey embryos, showing survival, proliferation, and insights into species-specific development, advancing regenerative medicine…

에스오디 SOD · Oct 2, 2023 281,957 views

Creating Humanized Kidneys in Pigs Using Induced Stem Cells

Researchers developed human-pig chimeric kidney structures by enhancing stem cell viability and overexpressing pro-survival genes, advancing efforts to generate organs for regenerative medicine.

科学透镜 · Apr 30, 2024 665 views

Creating Humanized Organs in Pigs Using Stem Cell Technology

Researchers generate human-pig chimeric kidneys by improving stem cell cultures and gene expression, advancing organ transplantation and regenerative medicine.

4ZZZ Podcasts · Oct 16, 2024 0 views

旅人 tabito

@tabibito250 · X

RT @023hjbyf: 【ブタの体内で人間の細胞を含む腎臓の培養に成功】 Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo comple…

Aug 18, 2024 · 3 shares · 1,075 followers View post →

BoichenkoSergey

@Sergulion · X

@Eraser_stp Немного в курсе. https://t.co/x5UgbOFu85

Feb 16, 2024 · 1 like · 438 followers View post →

Shingo Hatakeyama

@ShingoHatakeya1 · X

Dec 24, 2023 · 9 likes · 2,352 followers View post →

OmarTaco MD, MSc

@Errantnephron · X

@SENefrologia @senjoven @SENTRAsplante 8⃣ Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation #Senefro23 https://t.co/YtJS160hoZ https://t.co/lVwDSoAz6p

Nov 12, 2023 · 3 likes · 1,733 followers View post →

Alessandro Blasimme

@a_blasimme · X

Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation: Cell Stem Cell https://t.co/peqRms99C5

Nov 1, 2023 · 490 followers View post →

堅あげポテト

@a49991875 · X

RT @023hjbyf: 【ブタの体内で人間の細胞を含む腎臓の培養に成功】 Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo comple…

Oct 22, 2023 · 3 shares · 117 followers View post →

Cryingフリーランス

@cJiUrYtPO9qqY8R · X

@ShingoHatakeya1 これでしょうか？ https://t.co/2r6WtzO4Lt

Sep 26, 2023 · 1 like · 304 followers View post →

ryo694

@ryo694 · X

Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation https://t.co/ncmnrQDLBr

Sep 19, 2023 · 1,384 followers View post →

Yinpeng Zhan

@Zhanyinpeng · X

“Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation”

Sep 16, 2023 · 1,372 followers View post →

Miguel Ángel Sogorb

@MASogorb · X

Embrión de ser humano y de cerdo https://t.co/evmJWglhij Más información: Generation of a Humanized Mesonephros in Pigs from Induced Pluripotent Stem Cells via Embryo Complementation https://t.co/MMs0SUkWLg

Sep 16, 2023 · 158 followers View post →

Cena KX, MD.

@cenamdx · X

RT @CellStemCell: Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation https://t.co…

Sep 12, 2023 · 7 shares · 134 followers View post →

The ReNeural Project

@ReNeural · X

With all the talk about genetically modified #pigtohuman #organtransplants, called #xenotransplantation, few in the west know that the Chinese are exploring an alternative: introducing human #stemcells into pig embryos so that they grow human organs! https://t.co/28WfPTcQCI

Sep 12, 2023 · 408 followers View post →

Life Science Journal Content

@lsn_jc · X

Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation #science #publication #research #journal https://t.co/CDL295q0IV

Sep 12, 2023 · 260 followers View post →

KanzakiS

@nchdaks · X

Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation: Cell Stem Cell https://t.co/oEds4GUa63

Sep 12, 2023 · 677 followers View post →

旅人 tabito

@tabibito250 · X

RT @023hjbyf: 【ブタの体内で人間の細胞を含む腎臓の培養に成功】 Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo comple…

Sep 11, 2023 · 3 shares · 1,075 followers View post →

Max Lycke

@MaxLycke · X

RT @CellStemCell: Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation https://t.co…

Sep 11, 2023 · 7 shares · 71 followers View post →

ぜのぱす（初代_凍結から快復）

@Xenopus007 · X

https://t.co/ZqqXD8sNCB

Sep 11, 2023 · 853 followers View post →

医学部学士編入塾Cell@予備校

@023hjbyf · X

Sep 11, 2023 · 11 likes · 3 shares · 2,465 followers View post →

sara

@sara40000746 · X

Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation: Cell Stem Cell https://t.co/OIQ5IQrmyN

Sep 11, 2023 · 14 followers View post →

Abstream

@abstreamme · X

Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation #science #publication #research #publications https://t.co/uldpsBri4I

Sep 10, 2023 · 788 followers View post →

@007Ttk007 · X

RT @CellPressNews: "Generation of a Humanized Mesonephros in Pigs from Induced Pluripotent Stem Cells via Embryo Complementation" Read mor…

Sep 10, 2023 · 6 shares · 37 followers View post →

Ankit Singla

@In_AnkitSingla · X

RT @CellPressNews: "Generation of a Humanized Mesonephros in Pigs from Induced Pluripotent Stem Cells via Embryo Complementation" Read mor…

Sep 10, 2023 · 6 shares · 1,480 followers View post →

Mingxi

@MingxiWeng · X

RT @CellPressNews: "Generation of a Humanized Mesonephros in Pigs from Induced Pluripotent Stem Cells via Embryo Complementation" Read mor…

Sep 10, 2023 · 6 shares · 15 followers View post →

Jaroslav Novotný

@novotnyjarosl · X

RT @CellPressNews: "Generation of a Humanized Mesonephros in Pigs from Induced Pluripotent Stem Cells via Embryo Complementation" Read mor…

Sep 9, 2023 · 6 shares · 607 followers View post →

め

@hayo_kaeri_tai · X

RT @CellPressNews: "Generation of a Humanized Mesonephros in Pigs from Induced Pluripotent Stem Cells via Embryo Complementation" Read mor…

Sep 9, 2023 · 6 shares · 108 followers View post →

パワハラ耐性株

@Z_laboratorium · X

RT @CellPressNews: "Generation of a Humanized Mesonephros in Pigs from Induced Pluripotent Stem Cells via Embryo Complementation" Read mor…

Sep 9, 2023 · 6 shares · 1,207 followers View post →

Cell Press

@CellPressNews · X

"Generation of a Humanized Mesonephros in Pigs from Induced Pluripotent Stem Cells via Embryo Complementation" Read more in @cellstemcell https://t.co/6dskLYnRJ5

Sep 9, 2023 · 18 likes · 6 shares · 160,821 followers View post →

Rubén Anguiano

@rubenanguiano · X

Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation https://t.co/PgljYHfV82

Sep 8, 2023 · 4,044 followers View post →

Rubén Anguiano

@rubenanguiano · X

Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation: Cell Stem Cell https://t.co/JIRHSjILfF

Sep 8, 2023 · 4,044 followers View post →

Kitty Gifford

@myndwalk · X

@biog3500 Good recap. Turning the research article title "Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation" into "Scientists grow humanized kidneys in pig embryos" makes it much more understandable, no?

Sep 8, 2023 · 919 followers View post →

Andy_Weeble_Weaver

@AndrewW66619812 · X

The paper in "Cell: Stem Cell" the above "SCMP" article is based upon, & mentions: “Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation” 2/2 https://t.co/1TtIOTfm77

Sep 8, 2023 · 4,315 followers View post →

Alejandro De Los Angeles, DPhil, MPH

@delosangeles520 · X

RT @CellStemCell: Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation https://t.co…

Sep 8, 2023 · 7 shares · 88 followers View post →

Dr.Sushree

@spriyadarshin10 · X

World's first: Human kidney cells grown in Pig embryo, this could fulfill the need of organ donation shortage https://t.co/StydVnW5mM

Sep 8, 2023 · 8 likes · 10,721 followers View post →

Bertrand_new

@NewBertrand · X

RT @CellStemCell: Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation https://t.co…

Sep 8, 2023 · 7 shares · 666 followers View post →

BingQing He 何冰清

@BingqingHE2023 · X

RT @CellPressNews: "Generation of a Humanized Mesonephros in Pigs from Induced Pluripotent Stem Cells via Embryo Complementation" Read mor…

Sep 8, 2023 · 3 shares · 73 followers View post →

Agingdoc

@agingdoc1 · X

Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation

Sep 8, 2023 · 5 likes · 41,312 followers View post →

Ciekawość.Nauka i Natura

@nauka_natura · X

Nerki wyhodowane z komórek ludzkich w zarodkach świń https://t.co/gqZQtOqDjh https://t.co/xjD8XewkmY

Sep 8, 2023 · 2 likes · 1,240 followers View post →

Mo Ebrahimkhani

@MoEbrahimkhani · X

Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation: Cell Stem Cell https://t.co/aiEbKoWWBQ

Sep 7, 2023 · 5 likes · 1,206 followers View post →

Le Tran Phuc Khoa

@LeTranPhucKhoa1 · X

RT @CellStemCell: Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation https://t.co…

Sep 7, 2023 · 7 shares · 264 followers View post →

Muhammad Naeem

@naeempunia · X

RT @CellStemCell: Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation https://t.co…

Sep 7, 2023 · 7 shares · 563 followers View post →

2438@ROM

@t2438 · X

RT @CellPressNews: "Generation of a Humanized Mesonephros in Pigs from Induced Pluripotent Stem Cells via Embryo Complementation" Read mor…

Sep 7, 2023 · 3 shares · 819 followers View post →

Jiajia Chen, PhD, PMP

@JiajiaChen15 · X

RT @CellStemCell: Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation https://t.co…

Sep 7, 2023 · 7 shares · 382 followers View post →

Cell Stem Cell

@CellStemCell · X

Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation https://t.co/plr1hAVCf8

Sep 7, 2023 · 19 likes · 7 shares · 58,415 followers View post →

@druoh · X

RT @itok10918: Hmm.... Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation: Cell…

Sep 7, 2023 · 1 share · 1,725 followers View post →

Yasuhide OHINATA ᓚᘏᗢ ᘛ⁐̤ᕐᐷ

@y_ohinata · X

RT @CellPressNews: "Generation of a Humanized Mesonephros in Pigs from Induced Pluripotent Stem Cells via Embryo Complementation" Read mor…

Sep 7, 2023 · 3 shares · 1,704 followers View post →

Keiichi Ito

@itok10918 · X

Hmm.... Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation: Cell Stem Cell https://t.co/gNrHSfko65

Sep 7, 2023 · 2 likes · 1 share · 1,244 followers View post →

manuel macia heras

@mmacia25 · X

Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation: Cell Stem Cell https://t.co/iDm7vs6PFb

Sep 7, 2023 · 807 followers View post →

Cell Press

@CellPressNews · X

"Generation of a Humanized Mesonephros in Pigs from Induced Pluripotent Stem Cells via Embryo Complementation" Read more in @cellstemcell https://t.co/6dskLYnRJ5

Sep 7, 2023 · 4 likes · 3 shares · 160,821 followers View post →

Mc Laurin

@versussocial · X

RT @juankaamez: Hito en la generación artificial de órganos: cultivan riñones humanos en embriones porcinos Generation of a humanized meso…

Sep 7, 2023 · 1 share · 679 followers View post →

Juan Carlos Amez

@juankaamez · X

Hito en la generación artificial de órganos: cultivan riñones humanos en embriones porcinos Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation https://t.co/pasCTDAw4k

Sep 7, 2023 · 2 likes · 1 share · 3,240 followers View post →

CVG

@gal_cvg · X

Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation: Cell Stem Cell https://t.co/ITkrUXVpNM

Sep 7, 2023 · 102 followers View post →

Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Human Pluripotent Stem Cells in Monkey Embryos for Regenerative Medicine

Creating Humanized Kidneys in Pigs Using Induced Stem Cells

Creating Humanized Organs in Pigs Using Stem Cell Technology