August 1986 PMID 3773649

Sepsis and cholestasis: the in vitro effects of bacterial products on 14C-taurocholate uptake by isolated rat hepatocytes.

G Y Minuk, N Rascanin, E S Sarjeant, C H Pai

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Mentions

Peak: 30 in May 2025

across 2 sources since Dec 2022

Extended reach

5,219,934

potential audience

Total likes

102,052

Video views

4,852,928

Mentions per month

Dec 2022 – Nov 2025

Where it's discussed

X / Twitter95 posts
YouTube2 videos

AI synopsis

What people are saying

Participants show strong interest by sharing personal health stories and natural remedies, such as citrate and fasting, which reflect curiosity about bacterial influences on kidney stones. Their tone is conversational and supportive, suggesting engagement with the topic but limited critical analysis, leading to a neutral agreement stance based on the article's findings about bacteria and cholestasis.

AgreementNeither agree nor disagree

Most discussions reference bacterial involvement and bacterial products in kidney stones, aligning with the article's focus on bacterial effects on cholestasis, leading to a neutral agreement score.

InterestHigh interest

Participants are highly interested, sharing detailed discussions about causes, natural remedies, and personal experiences related to kidney stones and bacterial influences.

EngagementModerate engagement

Social discussions show moderate engagement, with some sharing videos, asking questions, and giving advice, indicating active but not deeply analytical engagement.

ImpactModerate impact

These discussions may influence people's understanding of kidney stones' causes and treatments, but they don't seem to directly influence medical practices or research, resulting in a moderate impact trend.

Abstract in brief

The study investigates how bacterial products affect bile salt uptake in rat liver cells and finds that some bacteria, like Haemophilus influenzae, Pseudomonas aeruginosa, and Klebsiella pneumonia, strongly inhibit this process, while others have minor effects.
Importantly, the level of endotoxin produced by these bacteria does not directly relate to the degree of bile salt uptake inhibition, suggesting that factors other than endotoxin are responsible for impairing bile flow.
Overall, the research indicates that bacterial infections can cause cholestasis (bile flow blockage) through additional bacterial molecules besides endotoxins.

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All mentions

Bacterial Products' Impact on Liver Bile Salt Uptake and Cholestasis

The study investigates how bacterial products affect bile salt uptake in rat liver cells. It finds that certain bacteria strongly inhibit this process, suggesting bacterial infections can cause cholestasis through…

Dr. Berg - официальный русскоязычный канал · Jan 28, 2023 3,161,673 views

Uncovering Hidden Causes of Kidney Stones and Calcification Mechanisms

Explore groundbreaking insights into the underlying causes of kidney stones, including calcification and the role of nanobacteria. Discover how bacterial factors beyond endotoxins may impact stone formation and…

Dr. Eric Berg DC · Dec 25, 2022 1,691,255 views

Small fish in a pond

@VioletRay555 · X

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Nov 6, 2025 · 278 followers View post →

Small fish in a pond

@VioletRay555 · X

My husband could make a maraca from all the kidney stones he's passed over the years—he's got another one now that he'll have to get out. We have a regimen we follow to help him do it. Knowledge is power. https://t.co/oa2QGg7RNo

Nov 2, 2025 · 278 followers View post →

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