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J Am Chem Soc November 2023 PMID 37748140

Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation.

Ziwen Jiang, Yu-Hsuan Kuo, Michelle R Arkin

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Mentions

29
Peak: 19 in Sep 2023
across 4 sources since Sep 2023

Extended reach

412,915
potential audience

Total likes

65

Video views

96

Mentions per month

Sep 2023 – Nov 2023

Where it's discussed

  • X / Twitter24 posts
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  • News2 articles
  • YouTube1 videos

AI synopsis

What people are saying

The discussion reflects interest and moderate engagement through sharing the article, such as mentions of its tagline and researchers involved, with language that indicates curiosity rather than critique. The tone and content emphasize the importance of targeted degradation mechanisms, which suggests the research's potential to impact future therapeutic strategies.

AgreementModerate agreement

Most posts are neutral or slightly positive, sharing the article without strong disagreement or critique.

InterestHigh interest

Discussions show high curiosity and active sharing, indicating strong interest in the research topic.

EngagementModerate engagement

Posts include mentions of the publication's significance and links, suggesting moderate engagement with some detailed discussions.

ImpactModerate impact

While awareness is evident, concrete evidence of influence on experimental or clinical practices remains limited, leading to a moderate impact score.

Abstract in brief

  • Autophagy is a cellular process that breaks down large unwanted materials, and when it malfunctions, it can lead to issues like aging and neurodegenerative diseases.
  • Researchers created chimeras called AceTACs that can specifically target and degrade problematic proteins and organelles in mammalian cells.
  • These AceTACs work by mimicking natural autophagy receptors, allowing them to bind to both the target and the autophagosomal membrane, facilitating the degradation process effectively.
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Top posts

Most liked on X and Bluesky
J. Am. Chem. Soc.
@J_A_C_S · X

The latest issue of JACS is live! On the cover this week: "Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation". Read the article here ➡️ https://t.co/fz9BDx6NNn https://t.co/3HzRWIVs0x

Nov 8, 2023 · 23 likes · 6 shares · 185,450 followers View post →
J. Am. Chem. Soc.
@J_A_C_S · X

Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation | Journal of the American Chemical Society @UCSF @ZiwenJiang @MichelleArkin @ucsfpharmacy #Autophagy #Antibody #Fusion #Proteins #Targeted #Degradation https://t.co/h4KGu13XUB

Sep 26, 2023 · 20 likes · 4 shares · 185,450 followers View post →
Guillaume Laconde
@Glaconde34 · X

Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation | Journal of the American Chemical Society https://t.co/Xeu764fCgt

Sep 26, 2023 · 12 likes · 3 shares · 4,813 followers View post →
NobuoMaita
@nob_mai · X

Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation | Journal of the American Chemical Society https://t.co/4wETxMEXCc

Sep 25, 2023 · 9 likes · 5 shares · 1,072 followers View post →
Rahul Banerjee
@banerjee_r · X

RT @J_A_C_S: The latest issue of JACS is live! On the cover this week: "Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted…

Nov 8, 2023 · 6 shares · 11,573 followers View post →
Matt Disney
@disney_lab · X

RT @J_A_C_S: Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation | Journal of the American Chemical…

Sep 28, 2023 · 4 shares · 5,704 followers View post →

All mentions

Analio Dugarte
@analioj · X

RT @J_A_C_S: The latest issue of JACS is live! On the cover this week: "Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted…

Nov 9, 2023 · 6 shares · 2,190 followers View post →
Ayan Mukherjee
@ayanmuk34401189 · X

RT @J_A_C_S: The latest issue of JACS is live! On the cover this week: "Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted…

Nov 8, 2023 · 6 shares · 508 followers View post →
Rahul Banerjee
@banerjee_r · X

RT @J_A_C_S: The latest issue of JACS is live! On the cover this week: "Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted…

Nov 8, 2023 · 6 shares · 11,573 followers View post →
Lipi Thukral
@Sci_Lipi · X

RT @J_A_C_S: The latest issue of JACS is live! On the cover this week: "Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted…

Nov 8, 2023 · 6 shares · 4,084 followers View post →
Ziwen Jiang
@ZiwenJiang · X

RT @J_A_C_S: The latest issue of JACS is live! On the cover this week: "Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted…

Nov 8, 2023 · 6 shares · 171 followers View post →
J. Am. Chem. Soc.
@J_A_C_S · X

The latest issue of JACS is live! On the cover this week: "Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation". Read the article here ➡️ https://t.co/fz9BDx6NNn https://t.co/3HzRWIVs0x

Nov 8, 2023 · 23 likes · 6 shares · 185,450 followers View post →
Matt Disney
@disney_lab · X

RT @J_A_C_S: Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation | Journal of the American Chemical…

Sep 28, 2023 · 4 shares · 5,704 followers View post →
Rothstein Lab
@Rothstein_Lab · X

RT @J_A_C_S: Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation | Journal of the American Chemical…

Sep 28, 2023 · 4 shares · 1,288 followers View post →
Protein-Degraders
@ProtDegraders · X

RT @Glaconde34: Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation | Journal of the American Chemi…

Sep 27, 2023 · 3 shares · 487 followers View post →
Ingentium Huntington's Disease
@ingentium_hd · X

Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation. https://t.co/HDS2JJz3mg https://t.co/gxdSwKbsSd

Sep 26, 2023 · 362 followers View post →
Autophagy Papers
@AutophagyPapers · X

Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation https://t.co/s30wQlqY8n https://t.co/EjjdxFaJ95

Sep 26, 2023 · 1,701 followers View post →
Ziwen Jiang
@ZiwenJiang · X

RT @J_A_C_S: Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation | Journal of the American Chemical…

Sep 26, 2023 · 4 shares · 171 followers View post →
know thyself（子豚のオリバー)
@thyself_know · X

RT @nob_mai: Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation | Journal of the American Chemical…

Sep 26, 2023 · 5 shares · 1,224 followers View post →
a
@ayanosatoh · X

RT @nob_mai: Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation | Journal of the American Chemical…

Sep 26, 2023 · 5 shares · 623 followers View post →
ステイサム研究員
@sutadon_tabetai · X

RT @Glaconde34: Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation | Journal of the American Chemi…

Sep 26, 2023 · 3 shares · 1,483 followers View post →
ttk_235
@ttk_235 · X

RT @nob_mai: Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation | Journal of the American Chemical…

Sep 26, 2023 · 5 shares · 272 followers View post →
Receptors MDPI
@ReceptorsM · X

RT @Glaconde34: Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation | Journal of the American Chemi…

Sep 26, 2023 · 3 shares · 27 followers View post →
Guillaume Laconde
@Glaconde34 · X

Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation | Journal of the American Chemical Society https://t.co/Xeu764fCgt

Sep 26, 2023 · 12 likes · 3 shares · 4,813 followers View post →
Blaise Kimmel, PhD
@BlaiseKimmel · X

RT @J_A_C_S: Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation | Journal of the American Chemical…

Sep 26, 2023 · 4 shares · 1,025 followers View post →
J. Am. Chem. Soc.
@J_A_C_S · X

Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation | Journal of the American Chemical Society @UCSF @ZiwenJiang @MichelleArkin @ucsfpharmacy #Autophagy #Antibody #Fusion #Proteins #Targeted #Degradation https://t.co/h4KGu13XUB

Sep 26, 2023 · 20 likes · 4 shares · 185,450 followers View post →
J. Fernando Bazan @jfernandobazan.bsky.social
@jfernandobazan · X

RT @nob_mai: Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation | Journal of the American Chemical…

Sep 26, 2023 · 5 shares · 705 followers View post →
なんとかなるさ
@qRe50ZldkmjLkFI · X

RT @nob_mai: Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation | Journal of the American Chemical…

Sep 25, 2023 · 5 shares · 47 followers View post →
NobuoMaita
@nob_mai · X

Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation | Journal of the American Chemical Society https://t.co/4wETxMEXCc

Sep 25, 2023 · 9 likes · 5 shares · 1,072 followers View post →
けとん
@ken3_ketone · X

Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation (Open Access) https://t.co/YcnrZHIidf

Sep 25, 2023 · 2,193 followers View post →