Am Heart J January 2024 PMID 37758044

Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes and atherosclerotic cardiovascular disease: SURPASS-CVOT design and baseline characteristics.

Stephen J Nicholls, Deepak L Bhatt, John B Buse, Stefano Del Prato, Steven E Kahn, A Michael Lincoff, Darren K McGuire, Michael A Nauck, Steven E Nissen, Naveed Sattar, Bernard Zinman, Sophia Zoungas, Jan Basile, Amy Bartee, Debra Miller

Mentions

63
Peak: 12 in Sep 2023
across 5 sources since Sep 2023

Extended reach

125,555
potential audience

Total likes

118

Video views

1,560

Mentions per month

Sep 2023 – Sep 2025

Where it's discussed

  • X / Twitter47 posts
  • News11 articles
  • YouTube2 videos
  • Blogs2 articles
  • Bluesky1 posts

AI synopsis

What people are saying

Several discussions revolve around the implications of the SURPASS-CVOT trial, with users expressing their enthusiasm about the potential findings. Phrases like 'definitive evidence' and references to safety and efficacy highlight the gravity of the study. The use of terms like 'major adverse cardiovascular events' shows a serious tone, reflecting the weight of the research topic and fostering a sense of urgency in understanding its implications.

AgreementModerate agreement

Many discussions reflect a favorable view towards the findings of the publication, indicating an overall consensus about the study's relevance.

InterestHigh interest

Participants demonstrate a high level of curiosity and express eagerness to learn about the findings and their implications.

EngagementModerate engagement

While most discussions share information about the researchers and the study, deeper engagement is noted in certain posts that mention methodologies.

ImpactHigh impact

There is a strong belief among participants that the study will have a significant impact on the understanding of cardiovascular safety in diabetes treatment.

Abstract in brief

  • Tirzepatide, a medication for type 2 diabetes, is being evaluated in a large cardiovascular outcomes trial to assess its safety and effectiveness compared to dulaglutide, another diabetes treatment.
  • The study involves adults with type 2 diabetes and existing cardiovascular disease, focusing on the occurrence of major adverse cardiovascular events (MACE) over time.
  • The trial has enrolled over 13,000 participants worldwide, and results will clarify whether tirzepatide offers greater cardiovascular benefits than dulaglutide.

Top posts

Most liked on X and Bluesky
Ahmed Bennis MD
@drbennisahmed · X

Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes and atherosclerotic cardiovascular disease: SURPASS‐CVOT design and baseline characteristics SURPASS-CVOT will provide definitive evidence as to the CV safety https://t.co/jybZ9QXN6e

Aug 1, 2025 · 28 likes · 8 shares · 2,766 followers View post →
Ahmed Bennis MD
@drbennisahmed · X

Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes and atherosclerotic cardiovascular disease: SURPASS‐CVOT design and baseline characteristics In SURPASS-CVOT, Mounjaro achieved the primary objective by https://t.co/OasJutjTgz

Jul 31, 2025 · 21 likes · 9 shares · 2,766 followers View post →
Cristobal Morales
@CristobMorales · X

https://t.co/Cb48ScLN9y “Comparison of Tirzepatide and Dulaglutide on Major Adverse Cardiovascular Events in Participants with Type 2 Diabetes and Atherosclerotic Cardiovascular Disease: SURPASS-CVOT Design and Baseline Characteristics” Orgullosos de la gran contribución del los

Sep 28, 2023 · 17 likes · 11 shares · 17,073 followers View post →
Gregg Fonarow MD
@gcfmd · X

@djc795 @mvaduganathan @brendonneuen @CMichaelGibson @skathire @GoggleDocs @ankeetbhatt @dranulala @ShelleyZieroth @BevTchangMD @JavedButler1 https://t.co/WvnR0U7CaN https://t.co/eqYfK1gPpE

Jul 31, 2025 · 9 likes · 2 shares · 11,851 followers View post →
Gunnar Henrik Heine
@gunnar_heine · X

...and here comes BROADWAY, which proves safety and efficacy of obicetrapib in patients at high CV risk by @ProfSNicholls and team! https://t.co/j6NQ9gnOOt We recently had the honour to discuss BROOKLYN and BROADWAY with @ProfSNicholls @MarkusAtHome https://t.co/j8o1yQRNhK https://t.co/MDJ73H1zrq

May 16, 2025 · 5 likes · 1 share · 2,404 followers View post →
AmericanHeartJ
@AmericanHeartJ · X

OPEN ACCESS: Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes and atherosclerotic cardiovascular disease: SURPASS-CVOT design and baseline characteristics https://t.co/mkwZWhih7F #Cardiology https://t.co/1fntscNt6W

Jan 12, 2024 · 4 likes · 2 shares · 10,563 followers View post →

All mentions

Gunnar Henrik Heine
@gunnar_heine · X

More from @ProfSNicholls on obicetrapid @MarkusAtHome: https://t.co/jNOFnlGUef

Sep 1, 2025 · 2 likes · 2,404 followers View post →
キャスバルレムダイクン@learning medicine student.
@in6b85t4 · X

RT @drbennisahmed: Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes an…

Aug 4, 2025 · 9 shares · 46 followers View post →
キャスバルレムダイクン@learning medicine student.
@in6b85t4 · X

RT @drbennisahmed: Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes an…

Aug 4, 2025 · 8 shares · 46 followers View post →
Chih-Yao Hsu
@reclast · X

RT @drbennisahmed: Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes an…

Aug 1, 2025 · 8 shares · 19 followers View post →
Onye Nkuzi Mazi Mbonu Ojike “The Boycott King”
@rollschidi_0 · X

RT @drbennisahmed: Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes an…

Aug 1, 2025 · 8 shares · 1,204 followers View post →
lal0155
@lal0155 · X

RT @drbennisahmed: Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes an…

Aug 1, 2025 · 8 shares · 12 followers View post →
Youssef Kassab
@MolKassab · X

RT @drbennisahmed: Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes an…

Aug 1, 2025 · 8 shares · 7 followers View post →
Alejandro I. Pérez Cabeza
@alejandroipc2 · X

RT @drbennisahmed: Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes an…

Aug 1, 2025 · 9 shares · 1,165 followers View post →
Youssef Nader
@lifewithyn · X

RT @drbennisahmed: Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes an…

Aug 1, 2025 · 8 shares · 14 followers View post →
Dr. Michael Alexander
@MichaelAlexandp · X

RT @drbennisahmed: Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes an…

Aug 1, 2025 · 9 shares · 852 followers View post →
Ali ihsan OLUK
@KasosMete · X

RT @drbennisahmed: Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes an…

Aug 1, 2025 · 8 shares · 554 followers View post →
Ahmed Bennis MD
@drbennisahmed · X

Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes and atherosclerotic cardiovascular disease: SURPASS‐CVOT design and baseline characteristics SURPASS-CVOT will provide definitive evidence as to the CV safety https://t.co/jybZ9QXN6e

Aug 1, 2025 · 28 likes · 8 shares · 2,766 followers View post →
mpdehesaisidoro
@mpdehesaisidoro · X

RT @drbennisahmed: Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes an…

Jul 31, 2025 · 9 shares · 33 followers View post →
Steve Greene
@SJGreene_md · X

RT @drbennisahmed: Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes an…

Jul 31, 2025 · 9 shares · 3,260 followers View post →
Andrew J Sauer MD
@AndrewJSauer · X

RT @drbennisahmed: Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes an…

Jul 31, 2025 · 9 shares · 19,319 followers View post →
Dr. Anda Garay
@estumed · X

RT @drbennisahmed: Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes an…

Jul 31, 2025 · 9 shares · 180 followers View post →
Suman Biswas MD MBBS
@sumanbiswasmd · X

RT @gcfmd: @djc795 @mvaduganathan @brendonneuen @CMichaelGibson @skathire @GoggleDocs @ankeetbhatt @dranulala @ShelleyZieroth @BevTchangMD…

Jul 31, 2025 · 2 shares · 333 followers View post →
Mohammad Keykhaei, MD, MPH
@m_keykhaei · X

RT @gcfmd: @djc795 @mvaduganathan @brendonneuen @CMichaelGibson @skathire @GoggleDocs @ankeetbhatt @dranulala @ShelleyZieroth @BevTchangMD…

Jul 31, 2025 · 2 shares · 2,011 followers View post →
Gregg Fonarow MD
@gcfmd · X

@djc795 @mvaduganathan @brendonneuen @CMichaelGibson @skathire @GoggleDocs @ankeetbhatt @dranulala @ShelleyZieroth @BevTchangMD @JavedButler1 https://t.co/WvnR0U7CaN https://t.co/eqYfK1gPpE

Jul 31, 2025 · 9 likes · 2 shares · 11,851 followers View post →
right
@45president · X

RT @drbennisahmed: Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes an…

Jul 31, 2025 · 9 shares · 70 followers View post →
mocchi
@mocchi_ym · X

RT @drbennisahmed: Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes an…

Jul 31, 2025 · 9 shares · 214 followers View post →
Ahmed Bennis MD
@drbennisahmed · X

Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes and atherosclerotic cardiovascular disease: SURPASS‐CVOT design and baseline characteristics In SURPASS-CVOT, Mounjaro achieved the primary objective by https://t.co/OasJutjTgz

Jul 31, 2025 · 21 likes · 9 shares · 2,766 followers View post →
European Atherosclerosis Society
@society_eas · X

RT @gunnar_heine: ...and here comes BROADWAY, which proves safety and efficacy of obicetrapib in patients at high CV risk by @ProfSNicholls…

May 16, 2025 · 1 share · 6,216 followers View post →
Gunnar Henrik Heine
@gunnar_heine · X

...and here comes BROADWAY, which proves safety and efficacy of obicetrapib in patients at high CV risk by @ProfSNicholls and team! https://t.co/j6NQ9gnOOt We recently had the honour to discuss BROOKLYN and BROADWAY with @ProfSNicholls @MarkusAtHome https://t.co/j8o1yQRNhK https://t.co/MDJ73H1zrq

May 16, 2025 · 5 likes · 1 share · 2,404 followers View post →
markusathome
@markusathome.bsky.social · Bluesky

Are you ready for our new webinar? The CETP-Inhibitor Obicetrapib in FH: BROOKLYN - Prof. Dr. Stephen Nicholls (Melbourne, Australia) youtu.be/MMdSjYmlD-8?... Guest: Prof. Stephen Nicholls Hosts: @gunnarheine.bsky.social, Prof. Custodis, Prof. Schirmer

Mar 7, 2025 · 1 like · 2 shares View post →
markusathome
@MarkusAtHome · X

Are you ready for our new webinar? The CETP-Inhibitor Obicetrapib in FH: BROOKLYN - Prof. Dr. Stephen Nicholls (Melbourne, Australia) https://t.co/VkyxtIhliq Guest: @ProfSNicholls Hosts: @floriancustodis @StephanSchirme1 @gunnar_heine

Mar 7, 2025 · 3 likes · 118 followers View post →
Harmless Frog
@FrogHarmless · X

@KirkegaardEmil https://t.co/2gCbAryG8r

Jan 10, 2025 · 502 followers View post →
Neeraj
@Phrmacologist · X

RT @AmericanHeartJ: OPEN ACCESS: Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type…

Jan 17, 2024 · 2 shares · 279 followers View post →
AmericanHeartJ
@AmericanHeartJ · X

RT @AmericanHeartJ: OPEN ACCESS: Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type…

Jan 16, 2024 · 2 shares · 10,563 followers View post →
AmericanHeartJ
@AmericanHeartJ · X

OPEN ACCESS: Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes and atherosclerotic cardiovascular disease: SURPASS-CVOT design and baseline characteristics https://t.co/mkwZWhih7F #Cardiology https://t.co/1fntscNt6W

Jan 12, 2024 · 4 likes · 2 shares · 10,563 followers View post →
JORGE FERNANDEZ
@drjorfer · X

Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes and atherosclerotic cardiovascular disease: SURPASS‐CVOT design and baseline characteristics - ScienceDirect✅☑️✅☑️ https://t.co/ouVUTI8JWK

Dec 8, 2023 · 2 likes · 1,021 followers View post →
the paper link
@the_paper_link · X

Trend up+30: Nicholls SJ, ..., Surpass-cvot investigators (Am Heart J) __Comparison of Tirzepatide and Dulaglutide on Major Adverse Cardiovascular Events in Participants with Type 2 Diabetes and Atherosclerotic Cardiovascular Disease: SUR__ https://t.co/vZBiGlINT5

Oct 5, 2023 · 138 followers View post →
Baim Institute
@BaimInstitute · X

Oct 4, 2023 · 1 like · 1,228 followers View post →
Dr.Lama Amer, MD
@Dr_Lama_Amer · X

Comparison of Tirzepatide and Dulaglutide on Major Adverse Cardiovascular Events in Participants with Type 2 Diabetes and Atherosclerotic Cardiovascular Disease: SURPASS-CVOT Design and Baseline Characteristics.

Oct 2, 2023 · 1 like · 4,285 followers View post →
the paper link
@the_paper_link · X

Trend up+48: Nicholls SJ, ..., Surpass-cvot investigators (Am Heart J) __Comparison of Tirzepatide and Dulaglutide on Major Adverse Cardiovascular Events in Participants with Type 2 Diabetes and Atherosclerotic Cardiovascular Disease: SUR__ https://t.co/vZBiGlINT5

Oct 1, 2023 · 138 followers View post →
JORGE FERNANDEZ
@drjorfer · X

Comparison of Tirzepatide and Dulaglutide on Major Adverse Cardiovascular Events in Participants with Type 2 Diabetes and Atherosclerotic Cardiovascular Disease: SURPASS-CVOT Design and Baseline Characteristics. - ScienceDirect✅☑️✅☑️ https://t.co/ouVUTI8JWK

Oct 1, 2023 · 1,021 followers View post →
the paper link
@the_paper_link · X

Trend up+131: Nicholls SJ, ..., Surpass-cvot investigators (Am Heart J) __Comparison of Tirzepatide and Dulaglutide on Major Adverse Cardiovascular Events in Participants with Type 2 Diabetes and Atherosclerotic Cardiovascular Disease: SU__ https://t.co/vZBiGlINT5

Sep 30, 2023 · 138 followers View post →
Fernando Vidal-Ostos De Lara
@drvidalostos · X

RT @CristobMorales: https://t.co/Cb48ScLN9y “Comparison of Tirzepatide and Dulaglutide on Major Adverse Cardiovascular Events in Participan…

Sep 29, 2023 · 11 shares · 441 followers View post →
Charles Herbert
@Charles_H_Best · X

RT @CristobMorales: https://t.co/Cb48ScLN9y “Comparison of Tirzepatide and Dulaglutide on Major Adverse Cardiovascular Events in Participan…

Sep 29, 2023 · 11 shares · 5 followers View post →
Oscar Moreno #
@moreno_perez_o · X

RT @CristobMorales: https://t.co/Cb48ScLN9y “Comparison of Tirzepatide and Dulaglutide on Major Adverse Cardiovascular Events in Participan…

Sep 29, 2023 · 11 shares · 3,399 followers View post →
SAEDYN
@SAEDYN_ · X

RT @CristobMorales: https://t.co/Cb48ScLN9y “Comparison of Tirzepatide and Dulaglutide on Major Adverse Cardiovascular Events in Participan…

Sep 28, 2023 · 11 shares · 3,776 followers View post →
Juan Carlos Obaya
@jcobaya69 · X

RT @CristobMorales: https://t.co/Cb48ScLN9y “Comparison of Tirzepatide and Dulaglutide on Major Adverse Cardiovascular Events in Participan…

Sep 28, 2023 · 11 shares · 858 followers View post →
fausto heredia z.
@drfherediaz · X

RT @CristobMorales: https://t.co/Cb48ScLN9y “Comparison of Tirzepatide and Dulaglutide on Major Adverse Cardiovascular Events in Participan…

Sep 28, 2023 · 11 shares · 4,354 followers View post →
Alexis A.
@Alexis_arbra · X

RT @CristobMorales: https://t.co/Cb48ScLN9y “Comparison of Tirzepatide and Dulaglutide on Major Adverse Cardiovascular Events in Participan…

Sep 28, 2023 · 11 shares · 220 followers View post →
Nicolas Renna, MD PhD ISHF FESC
@nicolasrennamd · X

RT @CristobMorales: https://t.co/Cb48ScLN9y “Comparison of Tirzepatide and Dulaglutide on Major Adverse Cardiovascular Events in Participan…

Sep 28, 2023 · 11 shares · 935 followers View post →
Juan Ignacio Arano
@AranoIgnacio · X

RT @CristobMorales: https://t.co/Cb48ScLN9y “Comparison of Tirzepatide and Dulaglutide on Major Adverse Cardiovascular Events in Participan…

Sep 28, 2023 · 11 shares · 92 followers View post →
Esteban Jódar Gimeno
@estebanjodar · X

RT @CristobMorales: https://t.co/Cb48ScLN9y “Comparison of Tirzepatide and Dulaglutide on Major Adverse Cardiovascular Events in Participan…

Sep 28, 2023 · 11 shares · 4,520 followers View post →
Cristobal Morales
@CristobMorales · X

https://t.co/Cb48ScLN9y “Comparison of Tirzepatide and Dulaglutide on Major Adverse Cardiovascular Events in Participants with Type 2 Diabetes and Atherosclerotic Cardiovascular Disease: SURPASS-CVOT Design and Baseline Characteristics” Orgullosos de la gran contribución del los

Sep 28, 2023 · 17 likes · 11 shares · 17,073 followers View post →