More evidence to suggest that if the brain is NOT metabolically stressed or compromised, even high dose #creatine likely to have no significant effects on cognition in young adults. https://t.co/qvPmo71qlf
Dose-Response of Creatine Supplementation on Cognitive Function in Healthy Young Adults.
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Sep 2023 – Dec 2025Where it's discussed
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X / Twitter42 posts
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YouTube2 videos
AI synopsis
What people are saying
The discussions predominantly agree that the study confirms creatine's minimal effects on cognition in healthy young adults, with phrases like 'no improvement' and 'does not significantly enhance,' demonstrating consensus. The tone remains cautious, referencing meta-analyses and emphasizing the need for more extensive research, which reflects moderate engagement and interest without overstating the findings.
Most discussions acknowledge the study's findings that creatine does not significantly improve cognitive function in healthy young adults, showing strong consensus.
There is moderate interest, as many comments focus on confirming existing evidence rather than exploring new implications.
Several users reference specific details of the study and related research, indicating thoughtful engagement, but it's not deeply analytical.
The conversation suggests limited immediate impact on practice, but some discussions highlight the need for further large-scale research, indicating a subtle influence on ongoing scientific discourse.
Abstract in brief
- The study investigated whether creatine supplementation affects cognitive performance and prefrontal cortex activation in healthy young adults over six weeks, with participants taking either 10 g/day, 20 g/day, or a placebo.
- Results showed that creatine, regardless of dosage, did not significantly improve cognitive test scores or alter prefrontal cortex activity, although a slight decrease in PFC oxyhemoglobin was observed in the lower dose group.
- Overall, the findings suggest that six weeks of creatine supplementation at moderate to high doses does not enhance cognitive function or brain activation in young, healthy individuals.
Top posts
Most liked on X and BlueskyOverall, six weeks of Cr supplementation at a moderate or high dose (20 g/d) does not improve cognitive performance or change PFC activation in young adults. https://t.co/P359O0zy9J #mdpibrainsci via @BrainSci_MDPI
Dose–Response of Creatine Supplementation on Cognitive Function in Healthy Young Adults #creatine #brain @DrCreatine https://t.co/ZlXTSh1qgh “6 wk of Cr supplementation at a moderate or high dose does NOT improve cognitive performance or change PFC activation in young adults”
"Overall, six weeks of Cr supplementation at a moderate or high dose does not improve cognitive performance or change PFC activation in young adults." Dose–Response of Creatine Supplementation on Cognitive Function in Healthy Young Adults https://t.co/P359O0zy9J #mdpibrainsci via
@adalozzo Pues sobre la creatina son innumerables los metanalisis que no solo no la encuentran lesiva sino que otorga beneficios de todo orden en personas sanas. Candow DG. Dose-Response of Creatine Supplementation on Cognitive Function in Healthy Young Adults.10.3390/brainsci13091276.
@mackinprof @theproof @NanciGuestRDPhD @ScepticalDoctor @Veganella_ @EricRawsonPhD We still do not know a reliable dosing protocol. It’s becoming more clear that creatine likely has no cognitive benefits in healthy individuals, especially young. All studies are limited by very low sample sizes. Large scale RCT (using MRS) needed. https://t.co/qvPmo71qlf
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@theaboagyeboadi @FitFounder @fmfclips A dose–response study comparing 10 g and 20 g/day over 6 weeks in healthy young adults showed no improvement in cognitive performance. https://t.co/dQsg9XlT2M
@theaboagyeboadi @FitFounder @fmfclips A dose–response study comparing 10 g and 20 g/day over 6 weeks in healthy young adults showed no improvement in cognitive performance.https://t.co/dQsg9XlT2M
RT @MossoSanch: @adalozzo Pues sobre la creatina son innumerables los metanalisis que no solo no la encuentran lesiva sino que otorga benef…
@adalozzo Pues sobre la creatina son innumerables los metanalisis que no solo no la encuentran lesiva sino que otorga beneficios de todo orden en personas sanas. Candow DG. Dose-Response of Creatine Supplementation on Cognitive Function in Healthy Young Adults.10.3390/brainsci13091276.
@levelsio https://t.co/FFEHa25ket
RT @darrencandow: More evidence to suggest that if the brain is NOT metabolically stressed or compromised, even high dose #creatine likely…
RT @darrencandow: More evidence to suggest that if the brain is NOT metabolically stressed or compromised, even high dose #creatine likely…
RT @darrencandow: More evidence to suggest that if the brain is NOT metabolically stressed or compromised, even high dose #creatine likely…
RT @darrencandow: More evidence to suggest that if the brain is NOT metabolically stressed or compromised, even high dose #creatine likely…
RT @darrencandow: More evidence to suggest that if the brain is NOT metabolically stressed or compromised, even high dose #creatine likely…
RT @darrencandow: More evidence to suggest that if the brain is NOT metabolically stressed or compromised, even high dose #creatine likely…
RT @darrencandow: More evidence to suggest that if the brain is NOT metabolically stressed or compromised, even high dose #creatine likely…
RT @darrencandow: More evidence to suggest that if the brain is NOT metabolically stressed or compromised, even high dose #creatine likely…
More evidence to suggest that if the brain is NOT metabolically stressed or compromised, even high dose #creatine likely to have no significant effects on cognition in young adults. https://t.co/qvPmo71qlf
per day. - The Daily Pump @Schwarzenegger @BornFitness @ketch https://t.co/dwGY4iBTqP https://t.co/Ou8iclpmw0
@theproof @NanciGuestRDPhD @ScepticalDoctor @Veganella_ @EricRawsonPhD @darrencandow Moriarty T, Bourbeau K, Dorman K, Runyon L, Glaser N, Brandt J, Hoodjer M, Forbes SC, Candow DG. Dose–Response of Creatine Supplementation on Cognitive Function in Healthy Young Adults. Brain Sciences. 2023; 13(9):1276.
@mackinprof @theproof @NanciGuestRDPhD @ScepticalDoctor @Veganella_ @EricRawsonPhD We still do not know a reliable dosing protocol. It’s becoming more clear that creatine likely has no cognitive benefits in healthy individuals, especially young. All studies are limited by very low sample sizes. Large scale RCT (using MRS) needed. https://t.co/qvPmo71qlf
Link to full study: "Dose–Response of Creatine Supplementation on Cognitive Function in Healthy Young Adults"https://t.co/CsNPf4uLSb
RT @ExphysPhD: Study finds creatine supplementation doesn't significantly enhance cognitive performance in young adults, despite a slight t…
Study finds creatine supplementation doesn't significantly enhance cognitive performance in young adults, despite a slight trend in altered brain activation.
RT @JoseAntonioPhD: Overall, six weeks of Cr supplementation at a moderate or high dose (20 g/d) does not improve cognitive performance or…
RT @JoseAntonioPhD: Overall, six weeks of Cr supplementation at a moderate or high dose (20 g/d) does not improve cognitive performance or…
RT @JoseAntonioPhD: Overall, six weeks of Cr supplementation at a moderate or high dose (20 g/d) does not improve cognitive performance or…
RT @JoseAntonioPhD: Overall, six weeks of Cr supplementation at a moderate or high dose (20 g/d) does not improve cognitive performance or…
RT @JoseAntonioPhD: Overall, six weeks of Cr supplementation at a moderate or high dose (20 g/d) does not improve cognitive performance or…
Overall, six weeks of Cr supplementation at a moderate or high dose (20 g/d) does not improve cognitive performance or change PFC activation in young adults. https://t.co/P359O0zy9J #mdpibrainsci via @BrainSci_MDPI
RT @JoseAntonioPhD: "Overall, six weeks of Cr supplementation at a moderate or high dose does not improve cognitive performance or change P…
RT @JoseAntonioPhD: "Overall, six weeks of Cr supplementation at a moderate or high dose does not improve cognitive performance or change P…
RT @darrencandow: Dose–Response of Creatine Supplementation on Cognitive Function in Healthy Young Adults #creatine #brain @DrCreatine ht…
RT @JoseAntonioPhD: "Overall, six weeks of Cr supplementation at a moderate or high dose does not improve cognitive performance or change P…
RT @darrencandow: Dose–Response of Creatine Supplementation on Cognitive Function in Healthy Young Adults #creatine #brain @DrCreatine ht…
RT @darrencandow: Dose–Response of Creatine Supplementation on Cognitive Function in Healthy Young Adults #creatine #brain @DrCreatine ht…
RT @JoseAntonioPhD: "Overall, six weeks of Cr supplementation at a moderate or high dose does not improve cognitive performance or change P…
RT @jheilesonRD: Dose–Response of Creatine Supplementation on Cognitive Function in Healthy Young Adults "6-weeks of Cr suppl at a modera…
RT @JoseAntonioPhD: "Overall, six weeks of Cr supplementation at a moderate or high dose does not improve cognitive performance or change P…
"Overall, six weeks of Cr supplementation at a moderate or high dose does not improve cognitive performance or change PFC activation in young adults." Dose–Response of Creatine Supplementation on Cognitive Function in Healthy Young Adults https://t.co/P359O0zy9J #mdpibrainsci via
RT @darrencandow: Dose–Response of Creatine Supplementation on Cognitive Function in Healthy Young Adults #creatine #brain @DrCreatine ht…
RT @darrencandow: Dose–Response of Creatine Supplementation on Cognitive Function in Healthy Young Adults #creatine #brain @DrCreatine ht…
RT @darrencandow: Dose–Response of Creatine Supplementation on Cognitive Function in Healthy Young Adults #creatine #brain @DrCreatine ht…
Dose–Response of Creatine Supplementation on Cognitive Function in Healthy Young Adults #creatine #brain @DrCreatine https://t.co/ZlXTSh1qgh “6 wk of Cr supplementation at a moderate or high dose does NOT improve cognitive performance or change PFC activation in young adults”
RT @jheilesonRD: Dose–Response of Creatine Supplementation on Cognitive Function in Healthy Young Adults "6-weeks of Cr suppl at a modera…
Dose–Response of Creatine Supplementation on Cognitive Function in Healthy Young Adults "6-weeks of Cr suppl at a moderate or high dose does not improve cognitive performance or change PFC activation in young adults." https://t.co/Z8xXqb1ib1 #mdpibrainsci via @BrainSci_MDPI
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