Clin Cancer Res December 2023 PMID 37812492

OvaPrint-A Cell-free DNA Methylation Liquid Biopsy for the Risk Assessment of High-grade Serous Ovarian Cancer.

David N Buckley, Juan Pablo Lewinger, Gerald Gooden, Monique Spillman, Monica Neuman, X Mona Guo, Ben Yi Tew, Heather Miller, Varun U Khetan, Lee P Shulman, Lynda Roman, Bodour Salhia

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Mentions

92
Peak: 24 in Oct 2023
across 4 sources since Oct 2023

Extended reach

78,051
potential audience

Total likes

51

Video views

114

Mentions per month

Oct 2023 – Sep 2025

Where it's discussed

  • News60 articles
  • X / Twitter27 posts
  • Blogs4 articles
  • YouTube1 videos

AI synopsis

What people are saying

The discussions reflect a generally positive reception of OvaPrint, emphasizing its promising detection accuracy and potential as a revolutionary blood test, using phrases like 'gran avance' and 'great step.' However, some comments question how it compares to existing tests and express the need for further validation, illustrating a balanced view that recognizes both the innovation's promise and the gaps remaining.

AgreementModerate agreement

Most discussions acknowledge the potential of OvaPrint as a promising detection tool, with some expressing optimism about its specificity and clinical value.

InterestHigh interest

Posts show high interest, with many discussions highlighting the importance of early detection methods for ovarian cancer and mentioning the accuracy and novelty of OvaPrint.

EngagementModerate engagement

The engagement is moderate; users reference studies, mention specific features like DNA methylation, and compare OvaPrint with other tests, indicating a meaningful but not deeply critical discussion.

ImpactModerate impact

While some posts suggest significant potential for improving ovarian cancer detection, others recognize that more research and validation are needed before widespread adoption, reflecting cautious optimism.

Abstract in brief

  • The study developed a liquid biopsy test called OvaPrint that uses DNA methylation patterns to differentiate high-grade serous ovarian cancer (HGSOC) from benign ovarian masses, showing high accuracy with 95% positive predictive value.
  • OvaPrint was created by analyzing DNA from tissue and blood samples, identifying specific methylation regions, and building a classifier that can effectively detect HGSOC, although it is less sensitive for other types of ovarian cancer.
  • The test is promising for use in symptomatic women to assess the risk of HGSOC, but further studies are needed to confirm its effectiveness and to adapt it for other ovarian cancer types and asymptomatic screening.]

Top posts

Most liked on X and Bluesky
Hans Collin
@HansCollin2 · X

El cáncer de ovario es agresivo y por desgracia es difícil detectarlo a tiempo porque sus síntomas son poco específicos. ➤Hay un nuevo examen de sangre —llamado OvaPrint— que tiene una precisión >91% en la detección temprana de éste cáncer. ¡Gran avance! https://t.co/v0CXf687j4

Oct 21, 2023 · 30 likes · 17 shares · 2,065 followers View post →
Dr Hani Al-Afghani
@AfghaniHani · X

#معلومة_تهم_الباحثين

Oct 12, 2023 · 14 likes · 5 shares · 18,886 followers View post →
Clinical Cancer Research
@CCR_AACR · X

OvaPrint—A Cell-free DNA Methylation Liquid Biopsy for the Risk Assessment of High-grade Serous Ovarian Cancer: https://t.co/sgonFgBDrU #AACRovca25 https://t.co/501hb5AMl6

Sep 20, 2025 · 6 likes · 7,891 followers View post →
ctSEQpapers
@ctSEQ_papers · X

PubMed_ OvaPrint™ - a cell-free DNA methylation liquid biopsy for the risk assessment of high-grade serous ovarian cancer https://t.co/mvqK6Tgr4f

Oct 9, 2023 · 1 like · 161 followers View post →
Dr Hani Al-Afghani
@AfghaniHani · X

RT @AfghaniHani: #معلومة_تهم_الباحثين

Oct 13, 2023 · 5 shares · 18,886 followers View post →
Olufemi Talabi
@0gbeni · X

https://t.co/Uz39m1KcBG

Mar 31, 2024 · 10,305 followers View post →

All mentions

Clinical Cancer Research
@CCR_AACR · X

OvaPrint—A Cell-free DNA Methylation Liquid Biopsy for the Risk Assessment of High-grade Serous Ovarian Cancer: https://t.co/sgonFgBDrU #AACRovca25 https://t.co/501hb5AMl6

Sep 20, 2025 · 6 likes · 7,891 followers View post →
Olufemi Talabi
@0gbeni · X

https://t.co/Uz39m1KcBG

Mar 31, 2024 · 10,305 followers View post →
URPP Human Reproduction Reloaded | H2R
@UZH_H2R · X

OvaPrint—A Cell-free DNA Methylation Liquid Biopsy for the Risk Assessment of High-grade Serous Ovarian Cancer https://t.co/d7tOKXYFqW

Nov 15, 2023 · 690 followers View post →
Seiichi Mori
@seiichi_mori · X

OvaPrint™ – a cell-free DNA methylation liquid biopsy for the risk assessment of high-grade serous ovarian cancer https://t.co/RgeGNVWwE2 https://t.co/e7m7oTbAe0

Oct 24, 2023 · 312 followers View post →
krypky
@krypkykristina · X

RT @HansCollin2: El cáncer de ovario es agresivo y por desgracia es difícil detectarlo a tiempo porque sus síntomas son poco específicos.…

Oct 23, 2023 · 17 shares · 476 followers View post →
Leyda Sindoni
@LeydaSindoni · X

RT @HansCollin2: El cáncer de ovario es agresivo y por desgracia es difícil detectarlo a tiempo porque sus síntomas son poco específicos.…

Oct 23, 2023 · 17 shares · 103 followers View post →
María L.Gil Laureiro
@MaraLGilLaureir · X

RT @HansCollin2: El cáncer de ovario es agresivo y por desgracia es difícil detectarlo a tiempo porque sus síntomas son poco específicos.…

Oct 23, 2023 · 17 shares · 602 followers View post →
Javier Véliz Alvarad
@AVelizja · X

RT @HansCollin2: El cáncer de ovario es agresivo y por desgracia es difícil detectarlo a tiempo porque sus síntomas son poco específicos.…

Oct 22, 2023 · 17 shares · 111 followers View post →
fausto heredia z.
@drfherediaz · X

RT @HansCollin2: El cáncer de ovario es agresivo y por desgracia es difícil detectarlo a tiempo porque sus síntomas son poco específicos.…

Oct 22, 2023 · 17 shares · 4,354 followers View post →
Silvia Fernandez
@silvia_geomara · X

RT @HansCollin2: El cáncer de ovario es agresivo y por desgracia es difícil detectarlo a tiempo porque sus síntomas son poco específicos.…

Oct 22, 2023 · 17 shares · 110 followers View post →
Lisa Eng
@DoctorsFirst · X

Grail - cfDNA - 1 single test/50 cancers. why pay for 1 cfDNA like OvaPrint? OvaPrint™ – a cell-free DNA methylation liquid biopsy for the risk assessment of high-grade serous ovarian cancer https://t.co/MRLiWIcuAo

Oct 22, 2023 · 91 followers View post →
Mariaje
@Mariajesusromd · X

RT @HansCollin2: El cáncer de ovario es agresivo y por desgracia es difícil detectarlo a tiempo porque sus síntomas son poco específicos.…

Oct 22, 2023 · 17 shares · 55 followers View post →
DaniReuma
@dani_reuma · X

RT @HansCollin2: El cáncer de ovario es agresivo y por desgracia es difícil detectarlo a tiempo porque sus síntomas son poco específicos.…

Oct 22, 2023 · 17 shares · 362 followers View post →
Karol
@Karolina_346 · X

RT @HansCollin2: El cáncer de ovario es agresivo y por desgracia es difícil detectarlo a tiempo porque sus síntomas son poco específicos.…

Oct 22, 2023 · 17 shares · 194 followers View post →
Eder Andrés
@ederandres152 · X

RT @HansCollin2: El cáncer de ovario es agresivo y por desgracia es difícil detectarlo a tiempo porque sus síntomas son poco específicos.…

Oct 21, 2023 · 17 shares · 934 followers View post →
Robert Vera Gomez
@Bioorobert65 · X

RT @HansCollin2: El cáncer de ovario es agresivo y por desgracia es difícil detectarlo a tiempo porque sus síntomas son poco específicos.…

Oct 21, 2023 · 17 shares · 486 followers View post →
JAIRO PARRAGA BERNAL
@jparber11 · X

RT @HansCollin2: El cáncer de ovario es agresivo y por desgracia es difícil detectarlo a tiempo porque sus síntomas son poco específicos.…

Oct 21, 2023 · 17 shares · 101 followers View post →
Alberto Román
@alberto_roman83 · X

RT @HansCollin2: El cáncer de ovario es agresivo y por desgracia es difícil detectarlo a tiempo porque sus síntomas son poco específicos.…

Oct 21, 2023 · 17 shares · 2,470 followers View post →
Hans Collin
@HansCollin2 · X

El cáncer de ovario es agresivo y por desgracia es difícil detectarlo a tiempo porque sus síntomas son poco específicos. ➤Hay un nuevo examen de sangre —llamado OvaPrint— que tiene una precisión >91% en la detección temprana de éste cáncer. ¡Gran avance! https://t.co/v0CXf687j4

Oct 21, 2023 · 30 likes · 17 shares · 2,065 followers View post →
3obad__
@3obad_198 · X

RT @AfghaniHani: #معلومة_تهم_الباحثين

Oct 13, 2023 · 5 shares · 2,590 followers View post →
ReemA
@Reema_AA3 · X

RT @AfghaniHani: #معلومة_تهم_الباحثين

Oct 13, 2023 · 5 shares · 96 followers View post →
Dr Hani Al-Afghani
@AfghaniHani · X

RT @AfghaniHani: #معلومة_تهم_الباحثين

Oct 13, 2023 · 5 shares · 18,886 followers View post →
Sattam Almalki
@sattam9974 · X

RT @AfghaniHani: #معلومة_تهم_الباحثين

Oct 12, 2023 · 5 shares · 3,889 followers View post →
riyad3eban
@riyad3eban · X

RT @AfghaniHani: #معلومة_تهم_الباحثين

Oct 12, 2023 · 5 shares · 560 followers View post →
Dr Hani Al-Afghani
@AfghaniHani · X

#معلومة_تهم_الباحثين

Oct 12, 2023 · 14 likes · 5 shares · 18,886 followers View post →
cfDNA papers
@cfDNA_papers · X

OvaPrint™ - a cell-free DNA methylation liquid biopsy for the risk assessment of high-grade serous ovarian cancer https://t.co/ItVArGVg7V https://t.co/aSukvwi3X5

Oct 9, 2023 · 621 followers View post →
ctSEQpapers
@ctSEQ_papers · X

PubMed_ OvaPrint™ - a cell-free DNA methylation liquid biopsy for the risk assessment of high-grade serous ovarian cancer https://t.co/mvqK6Tgr4f

Oct 9, 2023 · 1 like · 161 followers View post →