The summary reflects a shared recognition of the trial's importance, with examples like references to neurological dysfunction being more common with cefepime and mentions of the study’s presentation at major conferences. The tone is professional and focused on clinical implications, demonstrating high engagement and interest in evidence-based practice changes.
AgreementModerate agreement
Most discussions support the findings, emphasizing that the study shows no significant difference in kidney injury risk and highlights increased neurological issues with cefepime, indicating general agreement with the publication's conclusions.
InterestHigh interest
Participants demonstrate high interest by referencing multiple presentations, the clinical significance of findings, and ongoing debates about antibiotic safety, signaling strong engagement with the topic.
EngagementHigh engagement
The discussions include summaries of trial results, links to the publication, expert opinions, and considerations for changing clinical practice, reflecting deep engagement.
ImpactHigh impact
The findings appear to influence clinical practice and research, evidenced by mentions of trial presentations, updates being trending, and calls for practice changes, indicating a high level of impact.
Abstract in brief
The ACORN randomized clinical trial compared the safety of cefepime and piperacillin-tazobactam in hospitalized adults receiving antibiotics for infection, focusing on risks of acute kidney injury and neurological issues.
The study involved 2511 patients, with no significant difference found in the highest stage of kidney injury or death between the two drugs within 14 days, although outcomes like major kidney events and delirium were secondary measures.
Overall, the findings suggest that both antibiotics have similar safety profiles regarding kidney injury and neurological outcomes in this patient population.
Aug 20, 2024 · 87 likes · 3 shares · 3,167 followersView post →
JC
Jonathan Chávez
@JonathanNefro · X
Las personas que reciben Piperacilina/tazobactam tuvieron la misma
Incidencia de lesión renal aguda
o algún evento renal mayor (~25%), al comparar con cefepime. Este último tuvo mayores complicaciones neurológicas
En ensayo clínico
#ISNyoung
JAMA 2023
10.1001/jama.2023.20583 https://t.co/xqYoKtRnek
Oct 15, 2023 · 77 likes · 23 shares · 37,974 followersView post →
田
田中竜馬
@ryoma_tanaka · X
「ゾシン vs. セフェピム」論争再燃か。
ACORN trialでは14日死亡率にも急性腎傷害(AKI)にも有意差はなく、意識障害はセフェピムの方が多いという結果だったけど、14日では短かったということ?
ACORN trial
https://t.co/OjA2BmNSW9 https://t.co/BXuqGWwjXb
May 27, 2024 · 70 likes · 7 shares · 21,495 followersView post →
矢Y
矢吹 拓 Taku Yabuki
@tyabu7973 · X
急性感染症の入院患者に対するCFPM vs TAZ/PIPCの非盲検 RCT(ACORN)がJAMAに出てました。
14日までの急性腎障害や死亡の複合アウトカムは有意差なし。
副次アウトカムではCFPMの方がせん妄や昏睡などの神経障害が多い結果だった。
https://t.co/G8rWftOatA
Nov 7, 2023 · 39 likes · 8 shares · 3,746 followersView post →
JM
Journal of Hospital Medicine
@JHospMedicine · X
#UpdatesInHM 6: Cefepime vs. Pip-Tazo
ACORN Trial
https://t.co/WNmjch3Rfh
PMID: 37837651
Diagnostic stewardship has become essential in clinical practice over the past decade, impacting patient care and public health. This episode discusses practical testing improvements, the role of AI, and how thoughtful…
CFPMは神経障害の可能性
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial - PubMed https://t.co/qlHqVchaAH
Among hospitalized adults, the risk of acute kidney injury did not differ between cefepime and piperacillin-tazobactam, but neurological dysfunction was more common with cefepime. Note that 77.2% were receiving vancomycin at enrollment. @JAMA_current
https://t.co/IHIhR1bbHA
Thank you to our very own Darla Fink, MD for presenting at our Pediatric Journal Club yesterday. Darla is our Chief Pediatric Critical Care Fellow. She presented: ACORN Trial: Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection. https://t.co/JrHVXG7goL
Esquema empírico con Cefepime Vs Pip-Tazo para pacientes hospitalizados con infección aguda: Resultados del ACORN Trial: #ATS2024
Sin diferencias en deterioro de función renal ni mortalidad, pero con cefepime más coma o delirio
May 21, 2024 · 2 likes · 1 share · 1,256 followersView post →
AM
Amin Mohamadi, MD, MPH
@AminMohamadiMD · X
RT @aaeminfo: Read the paper that they discussed, here: https://t.co/DhDwwWd7N3
Let us know your thoughts below!
Read the paper that they discussed, here: https://t.co/DhDwwWd7N3
Let us know your thoughts below!
May 16, 2024 · 1 like · 1 share · 14,516 followersView post →
A
AAEM
@aaeminfo · X
In this month's CCMS-AAEM paper discussion, members focused on a paper titled, "Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection".
Watch the Recorded Discussion: https://t.co/MLzrbtIsnJ
May 16, 2024 · 1 like · 14,516 followersView post →
JK
Juned Khan
@JunedKh47457225 · X
RT @serperm: @AnandVKulkarni2 @robertpdickson One of my recent favorite trials shared with me by @AshleySpannMD: prospective, pragmatic, a…
May 16, 2024 · 3 shares · 138 followersView post →
DV
Dr Nipun Verma
@drnipunverma · X
RT @serperm: @AnandVKulkarni2 @robertpdickson One of my recent favorite trials shared with me by @AshleySpannMD: prospective, pragmatic, a…
May 15, 2024 · 3 shares · 821 followersView post →
AK
Anand V Kulkarni
@AnandVKulkarni2 · X
RT @serperm: @AnandVKulkarni2 @robertpdickson One of my recent favorite trials shared with me by @AshleySpannMD: prospective, pragmatic, a…
May 15, 2024 · 3 shares · 3,941 followersView post →
MM
Marina Serper, MD, MS
@serperm · X
@AnandVKulkarni2 @robertpdickson One of my recent favorite trials shared with me by @AshleySpannMD: prospective, pragmatic, and randomized. No mortality difference between pip-tazo and cefepime. More neuro dysfunction with cefepime. https://t.co/WaWsUUP0bl
May 15, 2024 · 7 likes · 3 shares · 2,331 followersView post →
MS
Madiha Syed
@madihasyed85 · X
RT @SOCCA_CritCare: Check out the ACORN Trial from @JAMA_current evaluating the use of Cefepime and Zosyn and their risk of AKI and neurolo…
Check out the ACORN Trial from @JAMA_current evaluating the use of Cefepime and Zosyn and their risk of AKI and neurological dysfunction in treatment of hospitalized patients infection. https://t.co/olt2cT9kp9
What's your usual practice in regards to broad spectrum antibiotics? https://t.co/DihKG8TXEk
May 7, 2024 · 3 likes · 2 shares · 4,006 followersView post →
FS
Farmacovigilante sv
@DanielS93941533 · X
RT @drtimothyli: 5. Comparison of cefepime versus pip-tazo for adults hospitalized with acute
infection showed similar risk for acute kidne…
5. Comparison of cefepime versus pip-tazo for adults hospitalized with acute
infection showed similar risk for acute kidney
injury, but neurologic dysfunction was more
common with cefepime
⭐ACORN trial
The ACORN Trial: Among hospitalized adults, the risk of acute kidney injury did not differ between cefepime and piperacillin-tazobactam, but neurological dysfunction was more common with cefepime. #SHEASpring2024 https://t.co/B1TtyHp0G0
Apr 16, 2024 · 1 like · 5,683 followersView post →
Dr. Emily Montgomery, PGY-2 Emergency Medicine Pharmacy Resident from Tampa General Hospital, presented on "Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial." https://t.co/RR9sKVEKbz
Feb 22, 2024 · 130 shares · 151 followersView post →
AG
Antibiotic Steward Bassam Ghanem
@ABsteward · X
RT @ABsteward:
Feb 19, 2024 · 130 shares · 60,071 followersView post →
AH
Adnan Hajjiah
@ph_adnan · X
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial | Critical Care Medicine | JAMA | JAMA Network https://t.co/KxtThjokPl
RT @PulmCrit: PIPERACILLIN-TAZOBACTAM IS NOT NEPHROTOXIC: exploring the arc of a myth over time
this was clearly a myth in 2016:
https://t…
Feb 5, 2024 · 335 shares · 81 followersView post →
DV
Dušan Vlahović
@vlah58 · X
RT @ClaudioSandron3: In the ACORN randomised trial on 2511 adults with acute #infection in ED or ICU at enrollment, #Piperacillin_Tazobacta…
Jan 20, 2024 · 1 share · 2,343 followersView post →
CS
Claudio Sandroni
@ClaudioSandron3 · X
In the ACORN randomised trial on 2511 adults with acute #infection in ED or ICU at enrollment, #Piperacillin_Tazobactam (bolus + ext. infusion) was not associated with higher AKI rates vs. Cefepime (10.2 vs. 8.8%).
https://t.co/G2bCckLre7 https://t.co/BxWu1IiWdz
Jan 18, 2024 · 1 like · 1 share · 261 followersView post →
SA
Somchai Amornyotin
@SAmornyotin · X
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection https://t.co/1FTzqNPNls
RT @WICSBottomLine: #TBL 443: ACORN - Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection
https://t.co/R7muTUXb…
Jan 10, 2024 · 2 shares · 2,429 followersView post →
SN
Syed Shahrul Naz
@drshahrul80 · X
RT @WICSBottomLine: #TBL 443: ACORN - Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection
https://t.co/R7muTUXb…
Jan 10, 2024 · 2 shares · 6,929 followersView post →
TL
The Bottom Line
@WICSBottomLine · X
#TBL 443: ACORN - Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection
https://t.co/R7muTUXbV9
Article by @EdQian
Review b @hgmwalker89
#FOAMed #FOAMcc #Sepsis https://t.co/lB1xQIGwJc
Jan 10, 2024 · 12 likes · 2 shares · 20,859 followersView post →
R
Rxtepen
@Rxtepen · X
RT @KBibbinsDomingo: Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial…
Jan 4, 2024 · 8 shares · 1,497 followersView post →
NA
NCAS_Australia
@NCAS_Aus · X
RT @KBibbinsDomingo: Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial…
Jan 4, 2024 · 8 shares · 3,816 followersView post →
SS
SCCM Clinical Pharmacy and Pharmacology Section
@SCCM_CPP · X
#CPPPLU Highlights. The ACORN RCT published in @JAMA_current found no difference in incidence of AKI between piperacillin-tazobactam and cefepime when used as empiric therapy. Patients who received cefepime had ↑ neurologic dysfunction. #PharmICU
https://t.co/p2NNlxiIql
Jan 3, 2024 · 2 likes · 3,450 followersView post →
Y
yyguu
@yyguu · X
RT @ABsteward:
Jan 2, 2024 · 130 shares · 510 followersView post →
B
B
@BERTLIU19 · X
RT @KBibbinsDomingo: Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial…
RT @KBibbinsDomingo: Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial…
Dec 30, 2023 · 8 shares · 121 followersView post →
AM
Ali Carroll, MD, MPH
@alisonrcarroll · X
RT @KBibbinsDomingo: Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial…
Dec 30, 2023 · 8 shares · 319 followersView post →
ME
Medicina Eterna
@Fvelaz · X
RT @KBibbinsDomingo: Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial…
Dec 30, 2023 · 8 shares · 297 followersView post →
TR
Todd Rice
@toddrice_ICU · X
RT @KBibbinsDomingo: Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial…
Dec 30, 2023 · 8 shares · 2,429 followersView post →
KD
Kirsten Bibbins-Domingo
@kbibbinsdomingo.bsky.social · Bluesky
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial - @EdQian @toddrice_ICU & colleagues jamanetwork.com/journals/jam...
One of our
RT @KBibbinsDomingo: Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial…
Dec 30, 2023 · 8 shares · 478 followersView post →
KD
Kirsten Bibbins-Domingo
@KBibbinsDomingo · X
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial - @EdQian @toddrice_ICU & colleagues https://t.co/xA5SHNaUbT
One of our
Dec 30, 2023 · 18 likes · 8 shares · 13,415 followersView post →
SN
Syed Shahrul Naz
@drshahrul80 · X
RT @IcuCast: Episode 26! A crossover episode with our pals at @PulmPEEPs! Thankful to them for giving us the opportunity to talk about the…
Dec 20, 2023 · 5 shares · 6,929 followersView post →
SS
Swapnil Hiremath @hswapnil.medsky.social
@hswapnil · X
@AstridWeins @VelezNephHepato There’s also this trial https://t.co/SPKyuvQTK9 which helps solve the confounding by sepsis greatly
(Though it cannot rule out rarer events of course) https://t.co/zXmBqhr1sO
Dec 18, 2023 · 1 like · 21,696 followersView post →
H
Hamad
@AdamQrs · X
RT @ABsteward:
Dec 13, 2023 · 130 shares · 62 followersView post →
RT @IcuCast: Episode 26! A crossover episode with our pals at @PulmPEEPs! Thankful to them for giving us the opportunity to talk about the…
Dec 12, 2023 · 5 shares · 897 followersView post →
KM
Kristina Montemayor
@KMonty_MD · X
RT @IcuCast: Episode 26! A crossover episode with our pals at @PulmPEEPs! Thankful to them for giving us the opportunity to talk about the…
Dec 12, 2023 · 5 shares · 1,594 followersView post →
LM
Luke Padgett Hedrick, MD
@luke_hedrick · X
RT @IcuCast: Episode 26! A crossover episode with our pals at @PulmPEEPs! Thankful to them for giving us the opportunity to talk about the…
Dec 12, 2023 · 5 shares · 370 followersView post →
PP
Pulm PEEPs
@PulmPEEPs · X
RT @IcuCast: Episode 26! A crossover episode with our pals at @PulmPEEPs! Thankful to them for giving us the opportunity to talk about the…
Dec 12, 2023 · 5 shares · 21,758 followersView post →
I
ICUEdandToddCast
@IcuCast · X
Episode 26! A crossover episode with our pals at @PulmPEEPs! Thankful to them for giving us the opportunity to talk about the ACORN trial (cefepime vs pip-tazo) which was published in @JAMA_current by... us (Ed and Todd)!
ACORN: https://t.co/iO7GoI1Bu0
https://t.co/qPyhTM3p2C https://t.co/a5784AqwOE
Dec 12, 2023 · 21 likes · 5 shares · 1,255 followersView post →
AG
A.R. García
@air_garcia · X
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection https://t.co/FEDulqtbSt
RT @SCCM_CPP: Is there a difference in AKI risk and neurological dysfunction when using cefepime vs piperacillin-tazobactam? Check out the…
Dec 11, 2023 · 6 shares · 4,489 followersView post →
SS
SCCM Clinical Pharmacy and Pharmacology Section
@SCCM_CPP · X
Is there a difference in AKI risk and neurological dysfunction when using cefepime vs piperacillin-tazobactam? Check out the ED Committee’s infographic by @kacyoldsen summarizing last month’s #SCCMJC #PharmICU
https://t.co/p2NNlxiIql https://t.co/f4PGE5t2YX
Dec 11, 2023 · 7 likes · 6 shares · 3,450 followersView post →
BA
BANGIN ANG
@versaceang · X
RT @KBibbinsDomingo: Read the ACORN trial here #ESICM #LIVES2023
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute In…
Dec 11, 2023 · 2 shares · 196 followersView post →
AP
ACCP Drug Info PRN
@accpdinfprn · X
Mark Your Calendars- Dr. Hanh Tran, PharmD, PGY1 Pharmacy Resident at Wellstar MCG Health, will present the ACORN trial: Cefepime vs piperacillin-tazobactam in adults hospitalized with acute infection. https://t.co/oKhfIVNWsV
Dec 6, 2023 · 2 likes · 1,064 followersView post →
PC
Prof Peter Collignon
@CollignonPeter · X
RT @ABsteward:
Dec 3, 2023 · 130 shares · 12,995 followersView post →
KT
Kishinami-Tokyo
@kishinami_tokyo · X
RT @ABsteward:
Dec 3, 2023 · 130 shares · 385 followersView post →
A
adagajak
@zftjhust · X
RT @ABsteward:
Dec 3, 2023 · 130 shares · 219 followersView post →
C
cookie
@qwiquiS · X
RT @ABsteward:
Dec 3, 2023 · 130 shares · 78 followersView post →
R
R
@rmoy52 · X
RT @ABsteward:
Dec 3, 2023 · 130 shares · 44 followersView post →
AG
Antibiotic Steward Bassam Ghanem
@ABsteward · X
RT @ABsteward:
Dec 3, 2023 · 130 shares · 60,071 followersView post →
JR
Jim Rhodes
@njrhodes_rx · X
@JamesWilsonDO1 @iddoctor @IdVilchez Not only does it happen but has major consequences for patients and is attributable to cefepime exposure NNH around 33 based on ACORN trial
doi: 10.1001/jama.2023.20583 https://t.co/MGiHnrkiDu
TAZ/PIPCはCFPMに比べのAKIのrisk有意差なかったとのこと
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection https://t.co/2kzMFL8iCD
Nov 12, 2023 · 6 likes · 1 share · 7,810 followersView post →
AL
ASHP Clinical Leadership
@ASHPClinLeaders · X
It's world pneumonia day. Have you changed your clinical practice based on the ACORN study? https://t.co/XEEYQTZd6K #pneumoniaday
#antibiotics #evidencebasedpractice
@SCCM @KiousenterlisN @nyphospital @ATSBlueEditor #SCCMJC #PharmICU Presenter 2:
Kacy Oldsen, PharmD @kacyoldsen PGY2 CC @MyMemorial
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection (ACORN) @JAMA_current
https://t.co/p2NNlxiIql
Nov 6, 2023 · 1 share · 3,450 followersView post →
MB
Marc Bonten
@MarcBonten · X
RT @KBibbinsDomingo: Top viewed this week at JAMA includes:
3️⃣ RCTs
IV Vitamin C for COVID-19 @remap_cap https://t.co/c2lrZAyJfa
Cefepi…
Nov 4, 2023 · 5 shares · 12,124 followersView post →
J
JAMA
@JAMA_current · X
RT @KBibbinsDomingo: Top viewed this week at JAMA includes:
3️⃣ RCTs
IV Vitamin C for COVID-19 @remap_cap https://t.co/c2lrZAyJfa
Cefepi…
Nov 4, 2023 · 5 shares · 488,643 followersView post →
KD
Kirsten Bibbins-Domingo
@KBibbinsDomingo · X
Top viewed this week at JAMA includes:
3️⃣ RCTs
IV Vitamin C for COVID-19 @remap_cap https://t.co/c2lrZAyJfa
Cefepime vs Pip-Taz in hospitalized patients https://t.co/LYL15f3W23
Traditional Chinese med Tongxinluo in patients with MI https://t.co/7yVMd65Zx1 https://t.co/LhkagxeaxD
Nov 4, 2023 · 16 likes · 5 shares · 13,415 followersView post →
Nov 1, 2023 · 27 shares · 492 followersView post →
SC
Sociedad de Medicina Interna de la CV
@smi_cv · X
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection
En pacientes hospitalizados el tratamiento con piper-tazo o cefepime no aumentó la incidencia de lesión renal aguda o muerte. Cefepime dio lugar a mayor disfunción neurológica https://t.co/sHS2D2qrfq
RT @KBibbinsDomingo: Most viewed in JAMA in last 7 days?
1️⃣-2nd week in a row
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized…
Oct 26, 2023 · 4 shares · 2,429 followersView post →
KD
Kirsten Bibbins-Domingo
@kbibbinsdomingo.bsky.social · Bluesky
Most viewed in JAMA in last 7 days?
1️⃣-2nd week in a row
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: ACORN RCT -Edward Qian et al jamanetwork.com/journals/jam...
Presented #IDWeek
Editorial jamanetwork.com/journals/jam...
#criticalcare #ID
RT @KBibbinsDomingo: Most viewed in JAMA in last 7 days?
1️⃣-2nd week in a row
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized…
Oct 26, 2023 · 4 shares · 721 followersView post →
EQ
Edward Qian
@EdQian · X
RT @KBibbinsDomingo: Most viewed in JAMA in last 7 days?
1️⃣-2nd week in a row
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized…
Oct 26, 2023 · 4 shares · 478 followersView post →
KD
Kirsten Bibbins-Domingo
@KBibbinsDomingo · X
Most viewed in JAMA in last 7 days?
1️⃣-2nd week in a row
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: ACORN RCT @EdQian @toddrice_ICU et al https://t.co/LYL15f3ocv
Presented #IDWeek @IDSAInfo
Editorial https://t.co/Rt8Y1rpdfH
#criticalcare https://t.co/WHlPrjtI4S
Oct 26, 2023 · 5 likes · 4 shares · 13,415 followersView post →
DD
Dr. Gagan Doke
@GaganDoke · X
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection
The study determines the risks of acute kidney injury or neurological dysfunction.
Cefepime resulted in more neurological dysfunction.
#medicine #antibiotics #JAMA
https://t.co/bxuGDzXYK8
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection https://t.co/cdFEbNBw55
Oct 25, 2023 · 2 likes · 6,349 followersView post →
AA
Ahmed AlHammadi
@TxIDdoc · X
RT @ABsteward:
Oct 25, 2023 · 130 shares · 912 followersView post →
AM
Andrew Michael South, MD, MS
@asouth_neph · X
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial | Critical Care Medicine | JAMA | JAMA Network https://t.co/5rhd7gmm4Q
Oct 24, 2023 · 3 likes · 3,382 followersView post →
MV
Marc Vives
@MarcVives13 · X
RT @tscquizzato: Now @EdQian presenting the second-last trial of the President’s session: Clinical trials in Intensive Care chaired by @Eli…
Oct 24, 2023 · 8 shares · 1,194 followersView post →
BP
Bailey Agee, PharmD
@BaileyAgeeRx · X
RT @ABsteward:
Oct 24, 2023 · 130 shares · 185 followersView post →
แว
แม่เรียกล้างจานแล้ว
@CtherP3 · X
RT @ABsteward:
Oct 24, 2023 · 130 shares · 195 followersView post →
UR
Un1v3rs0 Z3r0
@Un1v3rs0Z3r0 · X
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection https://t.co/0Zw8q5AAEP
Dr Edward Qian presents in the ESICM Opening President’s Session #LIVES2023 the results of ACORN published last week in JAMA
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial
jamanetwork.com/journals/jama/…
RT @tscquizzato: Now @EdQian presenting the second-last trial of the President’s session: Clinical trials in Intensive Care chaired by @Eli…
Oct 23, 2023 · 8 shares · 204 followersView post →
JN
JAMA Network
@JAMANetwork · X
Just presented in the #LIVES2023 Presidents' Session: Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial, from @JAMA_current, free to read online https://t.co/Hm8qLoJCUq https://t.co/aScMrjfqHP
Oct 23, 2023 · 2 likes · 1 share · 19,820 followersView post →
J
JAMA
@JAMA_current · X
Just presented in the #LIVES2023 Presidents' Session: Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial, from JAMA, free to read online https://t.co/lg3noPXBwM https://t.co/UFZhzIX7V0
Oct 23, 2023 · 7 likes · 3 shares · 488,643 followersView post →
GM
Giovanni Landoni, MD
@giovannilandoni · X
RT @KBibbinsDomingo: Dr Edward Qian @EdQian presents in the @ESICM Opening President’s Session #LIVES2023 the results of ACORN published la…
Oct 23, 2023 · 8 shares · 4,729 followersView post →
TM
Tommaso Scquizzato, MD
@tscquizzato · X
RT @KBibbinsDomingo: Dr Edward Qian @EdQian presents in the @ESICM Opening President’s Session #LIVES2023 the results of ACORN published la…
Oct 23, 2023 · 8 shares · 5,155 followersView post →
EQ
Edward Qian
@EdQian · X
RT @KBibbinsDomingo: Dr Edward Qian @EdQian presents in the @ESICM Opening President’s Session #LIVES2023 the results of ACORN published la…
Oct 23, 2023 · 8 shares · 478 followersView post →
KD
Kirsten Bibbins-Domingo
@KBibbinsDomingo · X
Read the ACORN trial here #ESICM #LIVES2023
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial
https://t.co/xA5SHNamml https://t.co/tJzIGuar5F
Oct 23, 2023 · 5 likes · 2 shares · 13,415 followersView post →
KD
Kirsten Bibbins-Domingo
@KBibbinsDomingo · X
Dr Edward Qian @EdQian presents in the @ESICM Opening President’s Session #LIVES2023 the results of ACORN published last week in JAMA @JAMA_current
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial https://t.co/zo2ws9Zqhk
Oct 23, 2023 · 25 likes · 8 shares · 13,415 followersView post →
JM
Jan De Waele MD
@criticcaredoc · X
RT @tscquizzato: Now @EdQian presenting the second-last trial of the President’s session: Clinical trials in Intensive Care chaired by @Eli…
Oct 23, 2023 · 8 shares · 7,972 followersView post →
TM
Tommaso Scquizzato, MD
@tscquizzato · X
Now @EdQian presenting the second-last trial of the President’s session: Clinical trials in Intensive Care chaired by @ElieAzoulay5 @criticcaredoc
The #ACORNtrial: Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection
Published recently in https://t.co/h25OarvcFT
Oct 23, 2023 · 27 likes · 8 shares · 5,155 followersView post →
Oct 23, 2023 · 1 share · 1,845 followersView post →
BC
Bryan Cotton
@bryanacotton1 · X
Things I learned halfway through my PGY-27 year, cefepime has ⬆️ risk neuro dysfunction
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial | Critical Care Medicine | JAMA | JAMA Network https://t.co/VjvVfB0Xi9
Oct 22, 2023 · 20 likes · 1 share · 5,041 followersView post →
PT
PubMed Trending
@PubTrend · X
Trending on PubMed: Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial. https://t.co/EJjgfAFHU2
Oct 21, 2023 · 3 likes · 1 share · 1,676 followersView post →
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MARY Aurélien
@MARYau_MCU_PH · X
RT @ABsteward:
Oct 20, 2023 · 130 shares · 1,444 followersView post →
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Kirsten Bibbins-Domingo
@kbibbinsdomingo.bsky.social · Bluesky
Top 5️⃣ viewed articles in JAMA in the last 7 days?
1️⃣
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial #MedSky
jamanetwork.com/journals/jama/…
RT @JonathanNefro: Las personas que reciben Piperacilina/tazobactam tuvieron la misma
Incidencia de lesión renal aguda
o algún evento rena…
Oct 17, 2023 · 23 shares · 134 followersView post →
AA
Arturo Aleman
@ElArturoAleman · X
RT @JonathanNefro: Las personas que reciben Piperacilina/tazobactam tuvieron la misma
Incidencia de lesión renal aguda
o algún evento rena…
Oct 16, 2023 · 23 shares · 409 followersView post →
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Helga
@Aisha12895124 · X
RT @JonathanNefro: Las personas que reciben Piperacilina/tazobactam tuvieron la misma
Incidencia de lesión renal aguda
o algún evento rena…
Oct 16, 2023 · 23 shares · 4,390 followersView post →
RV
Ricardo Alberto Cruz Villalobos
@Ricardo23cachi · X
RT @JonathanNefro: Las personas que reciben Piperacilina/tazobactam tuvieron la misma
Incidencia de lesión renal aguda
o algún evento rena…
Oct 16, 2023 · 23 shares · 23 followersView post →
DC
Dr. Miguel A. Cota:.
@macotav · X
RT @JonathanNefro: Las personas que reciben Piperacilina/tazobactam tuvieron la misma
Incidencia de lesión renal aguda
o algún evento rena…
Oct 16, 2023 · 23 shares · 1,513 followersView post →
MB
Malu Brown
@BrownMalu · X
RT @JonathanNefro: Las personas que reciben Piperacilina/tazobactam tuvieron la misma
Incidencia de lesión renal aguda
o algún evento rena…
Oct 16, 2023 · 23 shares · 358 followersView post →
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Doctoranefro
@DraJcadenanefro · X
RT @JonathanNefro: Las personas que reciben Piperacilina/tazobactam tuvieron la misma
Incidencia de lesión renal aguda
o algún evento rena…
Oct 16, 2023 · 23 shares · 779 followersView post →
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Motte
@AlvaradomotteA · X
RT @JonathanNefro: Las personas que reciben Piperacilina/tazobactam tuvieron la misma
Incidencia de lesión renal aguda
o algún evento rena…
Oct 16, 2023 · 23 shares · 495 followersView post →
PO
Patricia Oviedo
@patty8254 · X
RT @JonathanNefro: Las personas que reciben Piperacilina/tazobactam tuvieron la misma
Incidencia de lesión renal aguda
o algún evento rena…
Oct 15, 2023 · 23 shares · 339 followersView post →
JF
Juan Felipe
@Juanfebeme · X
RT @JonathanNefro: Las personas que reciben Piperacilina/tazobactam tuvieron la misma
Incidencia de lesión renal aguda
o algún evento rena…
Oct 15, 2023 · 23 shares · 25 followersView post →
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CLEESS
@CLEESS1 · X
RT @JonathanNefro: Las personas que reciben Piperacilina/tazobactam tuvieron la misma
Incidencia de lesión renal aguda
o algún evento rena…
Oct 15, 2023 · 23 shares · 181 followersView post →
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Marina
@Marina_nefro · X
RT @JonathanNefro: Las personas que reciben Piperacilina/tazobactam tuvieron la misma
Incidencia de lesión renal aguda
o algún evento rena…
Oct 15, 2023 · 23 shares · 948 followersView post →
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Carlos
@de_montecristo · X
RT @JonathanNefro: Las personas que reciben Piperacilina/tazobactam tuvieron la misma
Incidencia de lesión renal aguda
o algún evento rena…
Oct 15, 2023 · 23 shares · 2,735 followersView post →
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R David M
@RayMolinaL · X
RT @JonathanNefro: Las personas que reciben Piperacilina/tazobactam tuvieron la misma
Incidencia de lesión renal aguda
o algún evento rena…
Oct 15, 2023 · 23 shares · 601 followersView post →
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DogMeat
@MyOwnEnemyOP · X
RT @JonathanNefro: Las personas que reciben Piperacilina/tazobactam tuvieron la misma
Incidencia de lesión renal aguda
o algún evento rena…
Oct 15, 2023 · 23 shares · 333 followersView post →
LD
Luis Rodolfo Espinosa Dufour
@luis_dufour · X
RT @JonathanNefro: Las personas que reciben Piperacilina/tazobactam tuvieron la misma
Incidencia de lesión renal aguda
o algún evento rena…
Oct 15, 2023 · 23 shares · 69 followersView post →
EA
Edwin Abdul
@serolf_edwin · X
RT @JonathanNefro: Las personas que reciben Piperacilina/tazobactam tuvieron la misma
Incidencia de lesión renal aguda
o algún evento rena…
Oct 15, 2023 · 23 shares · 32 followersView post →
DL
Dr. Abraham Lotso
@abrahampremn16 · X
RT @JonathanNefro: Las personas que reciben Piperacilina/tazobactam tuvieron la misma
Incidencia de lesión renal aguda
o algún evento rena…
Oct 15, 2023 · 23 shares · 138 followersView post →
P
perropanson
@citarabino · X
RT @JonathanNefro: Las personas que reciben Piperacilina/tazobactam tuvieron la misma
Incidencia de lesión renal aguda
o algún evento rena…
Oct 15, 2023 · 23 shares · 1,446 followersView post →
DN
Dr. Ronald Caraballo NEFROLOGO
@ronald_nefro · X
RT @JonathanNefro: Las personas que reciben Piperacilina/tazobactam tuvieron la misma
Incidencia de lesión renal aguda
o algún evento rena…
Oct 15, 2023 · 23 shares · 664 followersView post →
BD
Beatrice Duarte
@Biaaraujodduart · X
RT @JonathanNefro: Las personas que reciben Piperacilina/tazobactam tuvieron la misma
Incidencia de lesión renal aguda
o algún evento rena…
Oct 15, 2023 · 23 shares · 28 followersView post →
JC
Jonathan Chávez
@JonathanNefro · X
Las personas que reciben Piperacilina/tazobactam tuvieron la misma
Incidencia de lesión renal aguda
o algún evento renal mayor (~25%), al comparar con cefepime. Este último tuvo mayores complicaciones neurológicas
En ensayo clínico
#ISNyoung
JAMA 2023
10.1001/jama.2023.20583 https://t.co/xqYoKtRnek
Oct 15, 2023 · 77 likes · 23 shares · 37,974 followersView post →
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial https://t.co/hOB6Xmu8lo https://t.co/S0R0VgAyak
Just published online first in JAMA & presented #IDWeek2023
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial
jamanetwork.com/journals/jam...
Original study DOI: 10.1001/jama.2023.20583 TBL: https://www.thebottomline.org.uk/summaries/icm/acorn/ Rebel EM: https://rebelem.com/the-acorn-trial ...
Original study DOI: 10.1001/jama.2023.20583 TBL: https://www.thebottomline.org.uk/summaries/icm/acorn/ Rebel EM: https://rebelem.com/the-acorn-trial ...
Original study DOI: 10.1001/jama.2023.20583 TBL: https://www.thebottomline.org.uk/summaries/icm/acorn/ Rebel EM: https://rebelem.com/the-acorn-trial ...
Original study DOI: 10.1001/jama.2023.20583 TBL: https://www.thebottomline.org.uk/summaries/icm/acorn/ Rebel EM: https://rebelem.com/the-acorn-trial ...
Original study DOI: 10.1001/jama.2023.20583 TBL: https://www.thebottomline.org.uk/summaries/icm/acorn/ Rebel EM: https://rebelem.com/the-acorn-trial ...
Original study DOI: 10.1001/jama.2023.20583 TBL: https://www.thebottomline.org.uk/summaries/icm/acorn/ Rebel EM: https://rebelem.com/the-acorn-trial ...
Original study DOI: 10.1001/jama.2023.20583 TBL: https://www.thebottomline.org.uk/summaries/icm/acorn/ Rebel EM: https://rebelem.com/the-acorn-trial ...