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This collection of discussions shows they are largely supportive of the study's conclusions, emphasizing the safety advantages of sertraline, with some critical mentions of problematic medications like Remeron and Effexor. The tone is analytical and informative, reflecting a keen interest in real-world clinical outcomes and potential changes in medication choices.
Most discussions agree with the study's findings that sertraline is safer for older adults compared to other antidepressants, with references to specific adverse outcomes associated with medications like mirtazapine and venlafaxine.
Participants demonstrate high interest by highlighting the large sample size and clinical relevance, such as questions about prescribing choices and safety profiles.
Posts engage with the study details, mentioning statistics, specific medications, and implications for clinical practice, indicating a moderate level of deliberation.
The discussions could influence prescribing practices and raise awareness about medication safety in older populations, showing some potential for real-world impact.
A study of more than 90,000 older adults initiating treatment for #depression examined clinical outcomes of the 10 most frequently used antidepressants. https://t.co/xWKkxcdkQY
Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating #Antidepressants for #Depression: A Nationwide Cohort Study in Denmark | American Journal of Psychiatry https://t.co/eel76LtgzJ
Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants for Depression: A Nationwide Cohort Study in Denmark | American Journal of Psychiatry https://t.co/ZdtwWPRqCQ
cohort study: Compared with older adults using sertraline, users of most of other 9 ADs had a higher risk of discontinuation, switching, augmentation, cardiovascular events, and mortality. Mirtazapine and venlafaxine users had the most adverse outcomes https://t.co/CRzEPyTXQf
Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants for Depression: A Nationwide Cohort Study in Denmark | American Journal of Psychiatry https://t.co/3bt9hvhRZ8
Remeron and Effexor were the most problematic in this large elder sample … “Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants for Depression: A Nationwide Cohort Study in Denmark” - PubMed https://t.co/9QJRik3yyf
American Journal of Psychiatry Deputy Editor Daniel S Pine discusses a nationwide Danish study on clinical outcomes of antidepressants in older adults, highlighting sertraline's favorable safety profile compared to…
American Journal of Psychiatry Deputy Editor Daniel S Pine MD discusses recent research on antidepressant outcomes in older adults, including a Danish cohort study comparing safety profiles of commonly prescribed…
https://t.co/yieIWOoJzR
RT @APAPubJournals: Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants fo…
RT @APAPubJournals: Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants fo…
RT @APAPubJournals: AJP Deputy Editor Danny Pine highlights two articles from the January 2024 issue: https://t.co/nW2mXs3LOE
AJP Deputy Editor Danny Pine highlights two articles from the January 2024 issue: https://t.co/nW2mXs3LOE
Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants for Depression: A Nationwide Cohort Study in Denmark https://t.co/kb4tP3Ivaz
cohort study: Compared with older adults using sertraline, users of most of other 9 ADs had a higher risk of discontinuation, switching, augmentation, cardiovascular events, and mortality. Mirtazapine and venlafaxine users had the most adverse outcomes https://t.co/CRzEPyTXQf
What antidepressant to use in people not previously treated https://t.co/vGhMOB0zzc
RT @yasseraddabbagh: Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants f…
https://ajp.psychiatryonline.org/doi/10.1176/appi.ajp.20230356?utm_campaign=journalupdate&utm_source=email&utm_medium=textlink&utm_content=ajp
Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants for Depression: A Nationwide Cohort Study in Denmark | American Journal of Psychiatry...
Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants for Depression: A Nationwide Cohort Study in Denmark | American Journal of Psychiatry https://t.co/ZdtwWPRqCQ
RT @APApsychiatric: A study of more than 90,000 older adults initiating treatment for #depression examined clinical outcomes of the 10 most…
RT @APApsychiatric: A study of more than 90,000 older adults initiating treatment for #depression examined clinical outcomes of the 10 most…
A study of more than 90,000 older adults initiating treatment for #depression examined clinical outcomes of the 10 most frequently used antidepressants. https://t.co/xWKkxcdkQY
https://t.co/ApoqZ7VyDs
Remeron and Effexor were the most problematic in this large elder sample … “Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants for Depression: A Nationwide Cohort Study in Denmark” - PubMed https://t.co/9QJRik3yyf
Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants for Depression: A Nationwide Cohort Study in Denmark | American Journal of Psychiatry https://t.co/W14BFWTyWn
RT @Luke_629: Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating #Antidepressants for #De…
Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants for Depression: A Nationwide Cohort Study in Denmark https://t.co/8fHXdqUmtU via @ishtiak10 et al
cohort study: Compared with older adult users of sertraline, users of most of the other 9 ADs had a ↑ risk of discontinuation (mirtazapine-IRR=1.55; venlafaxine: 1.22), switching (amitriptyline=1.45; venlafaxine: 1.47), augmentation, CV events, mortality https://t.co/CRzEPyTXQf
A study of more than 90,000 older adults initiating treatment for #depression examined clinical outcomes of the 10 most frequently used antidepressants. https://t.co/HAb2yHCs51 https://t.co/U6b71vSiU7
RT @Luke_629: Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating #Antidepressants for #De…
Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating #Antidepressants for #Depression: A Nationwide Cohort Study in Denmark | American Journal of Psychiatry https://t.co/eel76LtgzJ
Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants for Depression: A Nationwide Cohort Study in Denmark https://t.co/mnEMHqyvEL
Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants for Depression: A Nationwide Cohort Study in Denmark | American Journal of Psychiatry https://t.co/3bt9hvhRZ8
... ajp.psychiatryonline. org/doi/full/10.1176/appi.ajp.20230356 JAD (2021/10): Comparative effectiveness of antidepressants on geriatric depression: Real ...
DOI: 10.1176/appi.ajp.20230356 [URL]: https://psychiatryonline.org/doi/10.1176/appi.ajp.20230356.
DOI: 10.1176/appi.ajp.20230356 [URL]: https://psychiatryonline.org/doi/10.1176/appi.ajp.20230356.
... ajp.psychiatryonline. org/doi/full/10.1176/appi.ajp.20230356 JAD (2021/10): Comparative effectiveness of antidepressants on geriatric ...
Am J Psychiatry. 2024;doi:10.1176/appi.ajp.20230356. Disclosures: Ishtiak-Ahmed reports no relevant financial disclosures. Please see the study ...
... ajp.psychiatryonline. org/doi/full/10.1176/appi.ajp.20230356 JAD (2021/10): Comparative effectiveness of antidepressants on geriatric ...
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