Geroscience August 2024 PMID 37855862

Aging is associated with impaired triggering of TRPV3-mediated cutaneous vasodilation: a crucial process for local heat exposure.

Lisa S Martin, Audrey Josset-Lamaugarny, Thomas El Jammal, Sylvie Ducreux, Fabien P Chevalier, Bérengère Fromy

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Peak: 7 in Oct 2023

across 2 sources since Oct 2023

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5,902

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330

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Oct 2023 – Sep 2025

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The overall sentiment shows moderate engagement with the publication, demonstrated by sharing the research and expressing pride, such as noting the 'great job done' by a researcher. The tone remains positive but casual, reflecting a general awareness rather than intense debate or analysis of the findings.

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Abstract in brief

Sensing temperature is crucial for our body to adjust to environmental changes and protect tissues through mechanisms like cutaneous blood flow regulation.
Aging negatively affects the skin's ability to detect heat, particularly through the transient receptor potential vanilloid 3 (TRPV3) channels, which are vital for thermoregulation.
Research shows that older mice and human skin cells have reduced TRPV3 expression and activity, leading to impaired heat-induced vasodilation and possibly harming temperature detection and regulation.

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All mentions

Impact of Aging on Temperature Sensing and Thermoregulation

Aging impairs the skin's ability to detect heat via TRPV3 channels, which are vital for thermoregulation. This reduction in TRPV3 activity affects the body's capacity to respond to environmental temperature changes.

TimePie · Oct 20, 2023 329 views

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LBTI

@CNRSLbti · X

RT @GeroScienceAGE:

Oct 30, 2023 · 1 share · 196 followers View post →

TimePie (focus on anti-aging science)

@TimePieChina · X

If you missed the intriguing longevity news in the past week, check this video for weekly refreshments!

Oct 25, 2023 · 728 followers View post →

GeroScience

@GeroScienceAGE · X

Oct 23, 2023 · 6 likes · 1 share · 3,679 followers View post →

TimePie (focus on anti-aging science)

@TimePieChina · X

Oct 20, 2023 · 1 like · 742 followers View post →

Sandrine Le Goff

@sgosfflv · X

RT @GroupSkin: Happy to share the new publication of our group in @GeroScienceAGE about impact of #aging on heat changes perception by #sk…

Oct 19, 2023 · 1 share · 144 followers View post →

Skin Functional Integrity Group

@GroupSkin · X

Happy to share the new publication of our group in @GeroScienceAGE about impact of #aging on heat changes perception by #skin. Great job done by Lisa Martin during her thesis

Oct 19, 2023 · 4 likes · 1 share · 76 followers View post →