Geroscience June 2024 PMID 37855863

A variant in the 5'UTR of ERBB4 is associated with lifespan in Golden Retrievers.

Robert B Rebhun, Daniel York, Flora M D De Graaf, Paula Yoon, Kevin L Batcher, Madison E Luker, Stephanie Ryan, Jamie Peyton, Michael S Kent, Joshua A Stern, Danika L Bannasch

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Mentions

131

Peak: 25 in Oct 2023

across 6 sources since Oct 2023

Extended reach

1,433,399

potential audience

Total likes

5,987

Video views

73,758

Mentions per month

Oct 2023 – Apr 2025

Where it's discussed

News88 articles
X / Twitter31 posts
Blogs6 articles
YouTube3 videos
Facebook2 posts
Bluesky1 posts

AI synopsis

What people are saying

The social discussions feature enthusiastic reactions to the new genetic research, exemplified by posts asking whether golden retrievers can live longer and noting the discovery of a key gene associated with lifespan. Tone words like 'new', 'research', and expressions of curiosity indicate genuine interest, while references to the study's implications highlight a perception of meaningful scientific progress.

AgreementModerate agreement

Most discussions express support or interest in the genetic findings, with many posts acknowledging the significance of the ERBB4 variant in lifespan research.

InterestHigh interest

Posts demonstrate high curiosity, especially with phrases like 'Can golden retrievers live longer?' and references to new discoveries, indicating strong engagement with the topic.

EngagementModerate engagement

Several comments reference the genetic implications and potential applications, though not deeply analytical, showing moderate involvement.

ImpactModerate impact

The emphasis on the discovery being a 'new' gene associated with longevity suggests they see potential practical or scientific importance, though some posts focus on general excitement rather than detailed impact.

Abstract in brief

The study investigates genetic factors influencing lifespan in Golden Retrievers, focusing on a variant in the 5' untranslated region (UTR) of the ERBB4 gene, which is associated with shorter lifespan, especially in female dogs.
A specific haplotype (haplotype 3) in the ERBB4 5'UTR correlates with reduced survival, and dogs homozygous for this haplotype tend to die earlier, suggesting ERBB4 may play a role in longevity.
These findings imply that genetic studies within dog breeds can help identify variants that modify aging and disease risk, potentially informing similar research in humans.]

Read the full abstract

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Rochelle Lesser

@schoolpsyc.bsky.social · Bluesky

A variant in the 5′UTR of ERBB4 is associated with lifespan in Golden Retrievers

Feb 3, 2025 · 1 like · 1 share View post →

Manuel1900

@Manuel19003 · X

Esta IA puede VER tus pensamientos https://t.co/ogYv6UT4GO a través de @YouTube

Dec 4, 2023 · 381 followers View post →

Alejandro Montenegro

@aemonten · X

I would have expected this to be in Current Biology https://t.co/QUyDQCj0o7

Nov 26, 2023 · 2 likes · 9,045 followers View post →

Collins Efeizomor

@C_Gabbi_ · X

RT @DocDellaire: "5'UTR of ERBB4 is associated with lifespan in Golden Retrievers"

Nov 26, 2023 · 1 share · 158 followers View post →

Graham Dellaire @docdellaire.bsky.social

@DocDellaire · X

"5'UTR of ERBB4 is associated with lifespan in Golden Retrievers"

Nov 26, 2023 · 3 likes · 1 share · 2,667 followers View post →

Agingdoc

@agingdoc1 · X

A variant in the 5′UTR of ERBB4 is associated with lifespan in Golden Retrievers https://t.co/Y6jAPplbeO https://t.co/I7dji00Icz

Nov 12, 2023 · 3 likes · 41,943 followers View post →

Matt Yousefzadeh

@MattYousefzadeh · X

RT @AgingBiology: A variant in the 5′UTR of ERBB4 is associated with lifespan in Golden Retrievers https://t.co/nxxnFNjSm6

Nov 9, 2023 · 1 share · 4,791 followers View post →

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A variant in the 5′UTR of ERBB4 is associated with lifespan in Golden Retrievers https://t.co/nxxnFNjSm6

Nov 9, 2023 · 7 likes · 1 share · 30,820 followers View post →

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Oct 31, 2023 · 4 likes · 3,665 followers View post →

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Oct 23, 2023 · 160 likes · 16 shares · 183,288 followers View post →

NP AGARWAL世界一フォローを目指しますAiming best in world.

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RT @physorg_com: Can golden retrievers live longer? Researchers find gene associated with longevity in the breed https://t.co/Odfj8Qinot ht…

Oct 21, 2023 · 3 shares · 1,789 followers View post →

DogBot

@Dog_paper_bot · X

New dog paper! A variant in the 5'UTR of ERBB4 is associated with lifespan in Golden Retrievers https://t.co/soJIgNbe79

Oct 20, 2023 · 69 followers View post →

NPC-VET＠大学院

@feline_otyvet · X

ERBB4(HER4)のシグナル下流は最近ヒトの老化やアルツハイマー病に関連しているのではと注目されているところでもあります。 https://t.co/Xn4ryZl6bY

Oct 20, 2023 · 11 likes · 1,468 followers View post →

K W G

@mrpink714 · X

RT @physorg_com: Can golden retrievers live longer? Researchers find gene associated with longevity in the breed https://t.co/Odfj8Qinot ht…

Oct 19, 2023 · 3 shares · 246 followers View post →

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RT @physorg_com: Can golden retrievers live longer? Researchers find gene associated with longevity in the breed https://t.co/Odfj8Qinot ht…

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Can golden retrievers live longer? Researchers find gene associated with longevity in the breed https://t.co/Odfj8Qinot https://t.co/yxk6Ym0PFM

Oct 19, 2023 · 18 likes · 3 shares · 1,023,986 followers View post →

A variant in the 5'UTR of ERBB4 is associated with lifespan in Golden Retrievers.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

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Scientific Breakthroughs in Dog Research for 2025