Switch to oral antibiotics in Gram-negative bacteraemia: a randomized, open-label, clinical trial - Clinical Microbiology and Infection https://t.co/1OvNaAcX2H
Switch to oral antibiotics in Gram-negative bacteraemia: a randomized, open-label, clinical trial.
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Oct 2023 – Aug 2025Where it's discussed
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X / Twitter22 posts
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News2 articles
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Blogs2 articles
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YouTube1 videos
AI synopsis
What people are saying
Discussions highlight the trial’s key findings, such as the safety of switching from IV to oral antibiotics in stable patients, with phrases like 'effective and safe' and 'potentially changing standard care.' The tone is analytical and optimistic, emphasizing the significance of the research and its potential to impact treatment protocols.
Most discussions support the idea that switching to oral antibiotics is safe and effective, with several posts citing the trial's positive findings.
Posts show high interest, referencing specific aspects like patient stability and treatment protocols, indicating engagement with clinical details.
Many participants reference their own clinical experience or the trial design, showing moderate to deep engagement.
The conversations suggest that the publication could influence clinical practices, especially in streamlining treatments and reducing hospital stays.
Abstract in brief
- This study tested whether switching from IV to oral antibiotics after 35 days is safe and effective for patients with bloodstream infections caused by Enterobacterales, and found that oral therapy is not worse than continuing IV treatment in terms of treatment failure.
- The trial involved hospitalized adult patients who were stable and had no uncontrolled infection source, and compared outcomes between those who switched to oral antibiotics and those who stayed on IV, showing similar rates of treatment failure and adverse events.
- The results suggest that switching to oral antibiotics after initial IV treatment is a safe and effective option for certain patients, potentially reducing hospital stay and complications associated with IV therapy.]
Top posts
Most liked on X and Bluesky8. Early switch from IV to oral antibiotics in selected patients with gram-negative bacteremia was found to be effective and safe ⭐SOAB trial Caveats: ➡️>70% of the 1476 patients screened were ineligible ➡️Excluded IE, CNS infections and neutropenia https://t.co/Ws8jBgUGdx
Switch to oral antibiotics in Gram-negative bacteraemia: a randomized,... https://t.co/j879IqpIKj
【RCT】1つ以上の経口β-ラクタム系、キノロンまたはST合剤への感受性株による腸内細菌科単独の菌血症患者への3-5日間の静注治療後の経口薬への切り替えは、静注治療継続と比較して、治療失敗において非劣性であった。 #ペ読 https://t.co/zgF835pvgV
RT @LeonardLeibovi1: Switch to oral antibiotics in Gram-negative bacteraemia: a randomized, open-label, clinical trial - Clinical Microbiol…
RT @LeonardLeibovi1: Switch to oral antibiotics in Gram-negative bacteraemia: a randomized, open-label, clinical trial - Clinical Microbiol…
All mentions
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Switch to oral antibiotics in Gram-negative bacteraemia: a randomized, open-label, clinical trial - ScienceDirect https://t.co/ENUhbDuXx2
8. Early switch from IV to oral antibiotics in selected patients with gram-negative bacteremia was found to be effective and safe ⭐SOAB trial Caveats: ➡️>70% of the 1476 patients screened were ineligible ➡️Excluded IE, CNS infections and neutropenia https://t.co/Ws8jBgUGdx
RT @LeonardLeibovi1: Switch to oral antibiotics in Gram-negative bacteraemia: a randomized, open-label, clinical trial - Clinical Microbiol…
RT @LeonardLeibovi1: Switch to oral antibiotics in Gram-negative bacteraemia: a randomized, open-label, clinical trial - Clinical Microbiol…
RT @LeonardLeibovi1: Switch to oral antibiotics in Gram-negative bacteraemia: a randomized, open-label, clinical trial - Clinical Microbiol…
RT @LeonardLeibovi1: Switch to oral antibiotics in Gram-negative bacteraemia: a randomized, open-label, clinical trial - Clinical Microbiol…
RT @LeonardLeibovi1: Switch to oral antibiotics in Gram-negative bacteraemia: a randomized, open-label, clinical trial - Clinical Microbiol…
RT @LeonardLeibovi1: Switch to oral antibiotics in Gram-negative bacteraemia: a randomized, open-label, clinical trial - Clinical Microbiol…
RT @LeonardLeibovi1: Switch to oral antibiotics in Gram-negative bacteraemia: a randomized, open-label, clinical trial - Clinical Microbiol…
RT @LeonardLeibovi1: Switch to oral antibiotics in Gram-negative bacteraemia: a randomized, open-label, clinical trial - Clinical Microbiol…
RT @LeonardLeibovi1: Switch to oral antibiotics in Gram-negative bacteraemia: a randomized, open-label, clinical trial - Clinical Microbiol…
RT @LeonardLeibovi1: Switch to oral antibiotics in Gram-negative bacteraemia: a randomized, open-label, clinical trial - Clinical Microbiol…
RT @LeonardLeibovi1: Switch to oral antibiotics in Gram-negative bacteraemia: a randomized, open-label, clinical trial - Clinical Microbiol…
RT @LeonardLeibovi1: Switch to oral antibiotics in Gram-negative bacteraemia: a randomized, open-label, clinical trial - Clinical Microbiol…
RT @LeonardLeibovi1: Switch to oral antibiotics in Gram-negative bacteraemia: a randomized, open-label, clinical trial - Clinical Microbiol…
RT @LeonardLeibovi1: Switch to oral antibiotics in Gram-negative bacteraemia: a randomized, open-label, clinical trial - Clinical Microbiol…
Switch to oral antibiotics in Gram-negative bacteraemia: a randomized, open-label, clinical trial - Clinical Microbiology and Infection https://t.co/1OvNaAcX2H
Switch to oral antibiotics in Gram-negative bacteraemia: a randomized,... https://t.co/j879IqpIKj
Switch to Oral Antibiotics in Gram-negative Bacteraemia; a Randomised, Open-label, Clinical Trial https://t.co/LXAKpIcUon https://t.co/JPnhPXr9U0
RT @HucaProa: Estabilidad y control de foco. Continuar con IV no superior a tto oral. https://t.co/Fh13SntRjZ
Estabilidad y control de foco. Continuar con IV no superior a tto oral. https://t.co/Fh13SntRjZ
【RCT】1つ以上の経口β-ラクタム系、キノロンまたはST合剤への感受性株による腸内細菌科単独の菌血症患者への3-5日間の静注治療後の経口薬への切り替えは、静注治療継続と比較して、治療失敗において非劣性であった。 #ペ読 https://t.co/zgF835pvgV