Int J Cancer February 2024 PMID 37861205

Plasma cell-free DNA methylation analysis for ovarian cancer detection: Analysis of samples from a case-control study and an ovarian cancer screening trial.

Chiara Herzog, Allison Jones, Iona Evans, Daniel Reisel, Adeola Olaitan, Konstantinos Doufekas, Nicola MacDonald, Angelique Flöter Rådestad, Kristina Gemzell-Danielsson, Michal Zikan, David Cibula, Lukáš Dostálek, Tobias Paprotka, Andreas Leimbach, Markus Schmitt

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Mentions

10
Peak: 3 in Jan 2024
across 2 sources since Oct 2023

Extended reach

39,688
potential audience

Total likes

15

Video views

114

Mentions per month

Oct 2023 – Mar 2024

Where it's discussed

  • X / Twitter9 posts
  • YouTube1 videos

AI synopsis

What people are saying

The collective discussions express strong support and curiosity about the study's implications, with users frequently mentioning the potential for improved detection and early diagnosis, such as references to combining biomarkers and the need for larger trials. Words like 'could help,' 'may reduce mortality,' and 'future research needed' indicate cautious optimism and emphasize the study's significance within the broader context of ovarian cancer screening.

AgreementModerate agreement

Most discussions positively acknowledge the potential of cell-free DNA methylation analysis for early ovarian cancer detection, reflecting general support for the findings.

InterestHigh interest

Posts demonstrate high interest by highlighting new detection methods and expressing anticipation for future studies, indicating curiosity and engagement with the topic.

EngagementHigh engagement

Many comments reference technical aspects like biomarkers and study validation, showing deep engagement and a desire to understand the research implications.

ImpactModerate impact

The discussions suggest that this research could influence future screening practices, though some recognize the need for further validation before clinical adoption.

Top posts

Most liked on X and Bluesky
MRC Clinical Trials Unit at UCL
@MRCCTU · X

Researchers detected #OvarianCancer earlier by analysing cell-free DNA methylation in blood samples, according to a recent study. This could potentially improve #screening, but future research is needed to validate the results. Read now in @IntJCanc: https://t.co/9tl0Nk6zet

Jan 17, 2024 · 10 likes · 2 shares · 4,515 followers View post →
International Journal of Cancer
@IntJCanc · X

#OvarianCancerAwarenessMonth Analysis of cell-free DNA methylation, alone or combined with CA125 biomarker, could help to detect ovarian cancers earlier and may reduce mortality

Mar 11, 2024 · 2 likes · 2 shares · 1,788 followers View post →
International Journal of Cancer
@IntJCanc · X

NOW ONLINE The findings of this study indicate that combining cell-free DNA methylation analysis in three genetic regions with CA125 may improve the sensitivity of #OvarianCancer detection in high-risk women

Nov 28, 2023 · 1 like · 1,788 followers View post →
ArturasDobilas
@ArturasDobilas · X

Great article about ctDNA, looking forward to a study with a larger sample of patients. Or maybe someone knows or does a trail about ctDNA and OvarianCancer#? @OncoAlert @ESGO_society @nsgo_org @SGO_org https://t.co/ihKZEseAVU

Nov 2, 2023 · 1 like · 528 followers View post →
OVCA Papers
@OvcaPapers · X

Plasma cell-free DNA methylation analysis for ovarian cancer detection: Analysis of samples from a case-control study and an ovarian cancer screening trial https://t.co/fCzOb9KDcT

Oct 20, 2023 · 1 like · 157 followers View post →
Union for International #CancerControl
@uicc · X

RT @IntJCanc: #OvarianCancerAwarenessMonth Analysis of cell-free DNA methylation, alone or combined with CA125 biomarker, could help to de…

Mar 11, 2024 · 2 shares · 25,021 followers View post →

All mentions

Union for International #CancerControl
@uicc · X

RT @IntJCanc: #OvarianCancerAwarenessMonth Analysis of cell-free DNA methylation, alone or combined with CA125 biomarker, could help to de…

Mar 11, 2024 · 2 shares · 25,021 followers View post →
Yannick Romero, PhD
@YannickRomero · X

RT @IntJCanc: #OvarianCancerAwarenessMonth Analysis of cell-free DNA methylation, alone or combined with CA125 biomarker, could help to de…

Mar 11, 2024 · 2 shares · 657 followers View post →
International Journal of Cancer
@IntJCanc · X

#OvarianCancerAwarenessMonth Analysis of cell-free DNA methylation, alone or combined with CA125 biomarker, could help to detect ovarian cancers earlier and may reduce mortality

Mar 11, 2024 · 2 likes · 2 shares · 1,788 followers View post →
Bolton Cancer Voices
@VoicesBolton · X

RT @MRCCTU: Researchers detected #OvarianCancer earlier by analysing cell-free DNA methylation in blood samples, according to a recent stud…

Jan 17, 2024 · 2 shares · 1,345 followers View post →
UCL Population Health Sciences
@UCLPopHealthSci · X

RT @MRCCTU: Researchers detected #OvarianCancer earlier by analysing cell-free DNA methylation in blood samples, according to a recent stud…

Jan 17, 2024 · 2 shares · 3,751 followers View post →
MRC Clinical Trials Unit at UCL
@MRCCTU · X

Researchers detected #OvarianCancer earlier by analysing cell-free DNA methylation in blood samples, according to a recent study. This could potentially improve #screening, but future research is needed to validate the results. Read now in @IntJCanc: https://t.co/9tl0Nk6zet

Jan 17, 2024 · 10 likes · 2 shares · 4,515 followers View post →
International Journal of Cancer
@IntJCanc · X

NOW ONLINE The findings of this study indicate that combining cell-free DNA methylation analysis in three genetic regions with CA125 may improve the sensitivity of #OvarianCancer detection in high-risk women

Nov 28, 2023 · 1 like · 1,788 followers View post →
ArturasDobilas
@ArturasDobilas · X

Great article about ctDNA, looking forward to a study with a larger sample of patients. Or maybe someone knows or does a trail about ctDNA and OvarianCancer#? @OncoAlert @ESGO_society @nsgo_org @SGO_org https://t.co/ihKZEseAVU

Nov 2, 2023 · 1 like · 528 followers View post →
OVCA Papers
@OvcaPapers · X

Plasma cell-free DNA methylation analysis for ovarian cancer detection: Analysis of samples from a case-control study and an ovarian cancer screening trial https://t.co/fCzOb9KDcT

Oct 20, 2023 · 1 like · 157 followers View post →