Mol Neurodegener November 2023 PMID 37951933

Mitochondrial dysfunction in Parkinson's disease - a key disease hallmark with therapeutic potential.

Martin T Henrich, Wolfgang H Oertel, D James Surmeier, Fanni F Geibl

Mentions

60
Peak: 33 in Dec 2023
across 4 sources since Nov 2023

Extended reach

234,165
potential audience

Total likes

298

Video views

2,456

Mentions per month

Nov 2023 – Sep 2024

Where it's discussed

  • X / Twitter43 posts
  • News12 articles
  • Blogs3 articles
  • YouTube2 videos

AI synopsis

What people are saying

The discussions frequently emphasize mitochondrial dysfunction as a central element in Parkinson's disease, with phrases like 'key factor' and 'therapeutic potential' illustrating optimism about future treatments. The tone is mostly informative and supportive, with mentions of prevention strategies and implications for mental health supporting the overall perception that this research is crucial for advancing understanding and therapy development.

AgreementModerate agreement

Most posts acknowledge mitochondrial dysfunction as a key factor and support the idea that it could be a target for therapy, reflecting general consensus with the article's focus.

InterestHigh interest

Posts demonstrate high curiosity, with many emphasizing the importance of mitochondrial health and potential for prevention or treatment, indicating strong interest.

EngagementModerate engagement

While some posts comment on the implications and importance, few delve into detailed mechanisms or critique, showing moderate to deep engagement but not extensive discussion.

ImpactModerate impact

Several posts highlight the significance of understanding mitochondrial dysfunction for therapeutic development, suggesting moderate perceived impact but not overwhelmingly transformative.

Abstract in brief

  • Mitochondrial dysfunction is a major factor in the development of Parkinson's disease (PD), but attempts to treat the disease by fixing these mitochondrial issues, such as using antioxidants or iron chelators, have not yet been successful in clinical trials.
  • The review explains how problems in mitochondria—like damaged electron transport chains, increased oxidative stress, and faulty mitochondrial quality control—contribute to neuron death in PD.
  • It also discusses why current treatment strategies haven't worked so far and emphasizes the need to better understand mitochondrial pathways involved in neurodegeneration to develop more effective therapies.]

Top posts

Most liked on X and Bluesky
Chris Palmer, MD
@ChrisPalmerMD · X

People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognitive impairment, and other "mental health" symptoms. Why? "Mitochondrial dysfunction in Parkinson’s disease – a key disease hallmark" https://t.co/oviqMvo6fa

Dec 26, 2023 · 159 likes · 32 shares · 135,226 followers View post →
The Science of Parkinson's
@ScienceofPD · X

Researchers from @NUFeinbergMed provide a useful review of mitochondrial dysfunction in #Parkinsons https://t.co/AgejlnRK27 https://t.co/uwXznaQHuZ

Nov 12, 2023 · 7 likes · 3 shares · 10,885 followers View post →
Molecular Neurodegeneration
@MolNeuro · X

'#Mitochondrial dysfunction in #Parkinsons disease – a key disease hallmark with therapeutic potential' Martin T. Henrich, Wolfgang H. Oertel, D. James Surmeier, Fanni F. Geibl @Uni_MR @NUFeinbergMed https://t.co/ojO6WCpmJ2 https://t.co/IlsOrl16eH

Nov 13, 2023 · 3 likes · 2,941 followers View post →
Debbie Hampton
@dlhampton · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 11,721 followers View post →
Citizen of EU
@wavetossed · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 9,534 followers View post →
Nicole Laurent, LMHC
@KetoCounselor · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 9,034 followers View post →

All mentions

Alzheimer's Prevention
@AlzheimersPrev2 · X

@KitChri75116757 @dr_andrealove Genetics load the gun, lifestyle pulls the trigger. Mitochondrial dysfunction is a key factor in the development of Parkinson's disease. Therefore preventing the disease, not treating the neurodegeneration and subsequent disease would be ideal

Sep 4, 2024 · 372 followers View post →
Lars Baker
@larsswagger69 · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 29, 2023 · 32 shares · 31 followers View post →
Paul Sebastian
@PaulJSebastian · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 27, 2023 · 32 shares · 109 followers View post →
Bestill
@Bestill71072670 · X

Another reason to take care of your mitochondria. “Mitochondrial dysfunction is strongly implicated in the etiology of idiopathic and genetic Parkinson’s disease” https://t.co/nrAiBaQoxE

Dec 27, 2023 · 94 followers View post →
James Tang
@James69888 · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 27, 2023 · 32 shares · 1,600 followers View post →
Psyche.EduCare
@GlennSinclair · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 1,265 followers View post →
Coco
@AproposCoco · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 578 followers View post →
Joe A Kim
@Joe_A_Kim · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 748 followers View post →
Pablo Maure Inmunoterapia
@PInmunoterapia · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 1,512 followers View post →
ayunidalila
@miadelaila · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 123 followers View post →
Citizen of EU
@wavetossed · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 9,534 followers View post →
Theflowernurse
@theflowernurse · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 8,332 followers View post →
Magnesium guy. Scott Henrie
@10mm_404 · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 1,727 followers View post →
throw away
@throwawai7483 · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 23 followers View post →
Made To Measure Health
@m2measurehealth · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 28 followers View post →
concerned american
@biteme_suckas · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 6,770 followers View post →
Mind Your Science!
@MindYourSci · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 134 followers View post →
Tarik Fehmi
@Tarik_Fehmi · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 818 followers View post →
Nicole Laurent, LMHC
@KetoCounselor · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 9,034 followers View post →
Donald Sutherland
@DonSuths88 · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 1,580 followers View post →
Anssi H. Manninen | Mass Balance Man
@KingManninen · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 1,057 followers View post →
Sjoerd de Vries
@SjoerddeVries15 · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 237 followers View post →
Pedro E. de Felicio
@pedrodefelicio · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 2,486 followers View post →
LindaJ
@IronLindaJ · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 879 followers View post →
Serafina
@Serafina83837 · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 369 followers View post →
Marta Noya (Martouta)
@MartoutaTech · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 1,124 followers View post →
Debbie Hampton
@dlhampton · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 11,721 followers View post →
WJW Mental Health Legal Fund
@wjwmhlf · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 1,250 followers View post →
Mountain life
@mountainkeep · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 919 followers View post →
The Health Matrix
@healthmatrixnet · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 1,209 followers View post →
たこす。
@covit191919 · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 2,108 followers View post →
MaiaGoldberry☀️
@maiagoldberry · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 278 followers View post →
gw
@gwanony_ · X

RT @ChrisPalmerMD: People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognit…

Dec 26, 2023 · 32 shares · 338 followers View post →
Chris Palmer, MD
@ChrisPalmerMD · X

People with Parkinson's disease are more likely to have depression, anxiety, insomnia, hallucinations, delusions, cognitive impairment, and other "mental health" symptoms. Why? "Mitochondrial dysfunction in Parkinson’s disease – a key disease hallmark" https://t.co/oviqMvo6fa

Dec 26, 2023 · 159 likes · 32 shares · 135,226 followers View post →
Mitochondrial News
@MitochondriaNe1 · X

Mitochondrial dysfunction in Parkinson's disease - a key disease hallmark with therapeutic potential https://t.co/W4a0T0eWbu https://t.co/chS60GoVu2

Nov 13, 2023 · 2,257 followers View post →
Molecular Neurodegeneration
@MolNeuro · X

'#Mitochondrial dysfunction in #Parkinsons disease – a key disease hallmark with therapeutic potential' Martin T. Henrich, Wolfgang H. Oertel, D. James Surmeier, Fanni F. Geibl @Uni_MR @NUFeinbergMed https://t.co/ojO6WCpmJ2 https://t.co/IlsOrl16eH

Nov 13, 2023 · 3 likes · 2,941 followers View post →
Kevin McFarthing
@InnovationFixer · X

RT @Ingentium_PD: Mitochondrial dysfunction in Parkinson's disease - a key disease hallmark with therapeutic potential. https://t.co/1U4LQR…

Nov 13, 2023 · 1 share · 8,849 followers View post →
Ingentium Parkinson's Disease
@Ingentium_PD · X

Mitochondrial dysfunction in Parkinson's disease - a key disease hallmark with therapeutic potential. https://t.co/1U4LQRl2bn https://t.co/AqPs45SdqH

Nov 12, 2023 · 1 share · 515 followers View post →
Queromatics
@queromatics · X

Mitochondrial dysfunction in Parkinson's disease – a key disease ... - Molecular Neurodegeneration https://t.co/EVqlwwRl9c

Nov 12, 2023 · 46 followers View post →
Ioanna Ch. Georgiou
@IoannaCGeorgiou · X

RT @ScienceofPD: Researchers from @NUFeinbergMed provide a useful review of mitochondrial dysfunction in #Parkinsons https://t.co/AgejlnRK…

Nov 12, 2023 · 3 shares · 95 followers View post →
raj awatramani
@AwatramaniRaj · X

RT @ScienceofPD: Researchers from @NUFeinbergMed provide a useful review of mitochondrial dysfunction in #Parkinsons https://t.co/AgejlnRK…

Nov 12, 2023 · 3 shares · 151 followers View post →
The Science of Parkinson's
@ScienceofPD · X

Researchers from @NUFeinbergMed provide a useful review of mitochondrial dysfunction in #Parkinsons https://t.co/AgejlnRK27 https://t.co/uwXznaQHuZ

Nov 12, 2023 · 7 likes · 3 shares · 10,885 followers View post →
IronBiologyBot
@IronBiologyBot · X

Mitochondrial dysfunction in Parkinson's disease - a key disease hallmark with therapeutic potential https://t.co/K7ptRK6QYf #IronBiology #BioIron #Iron

Nov 12, 2023 · 288 followers View post →