With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev 6 from #ESC2023. This meta-analysis does just that. The trials are totally consistent: https://t.co/lOb1IxtaB3 #EPeeps
Direct Oral Anticoagulants for Stroke Prevention in Patients With Device-Detected Atrial Fibrillation: A Study-Level Meta-Analysis of the NOAH-AFNET 6 and ARTESiA Trials.
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Nov 2023 – May 2025Where it's discussed
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X / Twitter104 posts
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News18 articles
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YouTube2 videos
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Bluesky1 posts
AI synopsis
What people are saying
Numerous posts highlight key findings, such as the effective stroke reduction associated with direct oral anticoagulants like edoxaban and apixaban, while also cautioning about increased bleeding risks. Phrases like 'significant stroke reduction' and references to reconciling findings from different trials reflect a tone of urgency and importance, underscoring the implications these results may have for patient care and clinical guidelines.
Most discussions reflect a general endorsement of the findings from the publication and recognize its relevance to clinical practice.
A high volume of posts shows active interest in the topic, particularly given its implications for stroke prevention.
The discussions include references to the trials, yet some posts indicate uncertainty about certain aspects of the meta-analysis.
Many contributors express that the findings will significantly influence treatment strategies for atrial fibrillation.
Abstract in brief
- Direct oral anticoagulants (DOACs) are effective in reducing the risk of ischemic stroke in patients with device-detected atrial fibrillation, based on a meta-analysis of two significant trials: NOAH-AFNET 6 and ARTESiA.
- During the review of 785 citations, the analysis included 6,548 participants and found that using DOACs like edoxaban and apixaban significantly lowered the risk of ischemic strokes and other major cardiovascular events.
- The evidence quality varied, with high confidence in stroke reduction and moderate confidence in overall cardiovascular event reductions, but there was no notable decrease in cardiac death linked to anticoagulation therapy.
Top posts
Most liked on X and BlueskyAnd right on time is the meta-analysis from @WFMMD et al. Significant stroke reduction with no impact on mortality. https://t.co/KfLD0HLDBZ https://t.co/Fv5nj56OHW
Meta-Analysis of the NOAH-AFNET & ARTESiA Trials. Results are consistent: OAC with edoxaban or apixaban reduces the risk of stroke in patients with device-detected AF and increases the risk of major bleeding. https://t.co/2HsxJwxH5A (Stroke, Syst Embolism, MI, PE, CV Death) https://t.co/uzpNIt7YQA
#JustPublished #AHA23 #CIRCAHA23 In a meta analysis of 2 RCTS, DOAC use for device detected #AF was associated with⬇️risk of the composite of CV death, stroke, PE, arterial embolism and MI but⬆️risk of major bleeding @AlexanderPBenz @WFMMD #AHAJournals https://t.co/22f8nEdzgm
All mentions
Insights on KETOCTA Study and Stroke Prevention in AF Patients
This week’s podcast discusses the KETOCTA study and stroke prevention in patients with device-detected atrial fibrillation. Key findings from two significant trials highlight the effectiveness of direct oral…
Effectiveness of DOACs in Atrial Fibrillation Management
This week’s podcast reviews significant trials including NOAH-AFNET 6 and ARTESiA that highlight the role of direct oral anticoagulants (DOACs) in preventing ischemic stroke among patients with device-detected atrial…
Direct Oral Anticoagulants for Stroke Prevention in Atrial Fibrillation: A Global Synthesis of Randomized Evidence through Network Meta-Analysis https://www.medrxiv.org/content/10.1101/2025.05.18.25327653v1
RT @EHRAPresident: The #EHRAtopicWeek on device-detected AF How to manage device-detected AF? Anticoagulation prevents some strokes and in…
RT @EHRAPresident: The #EHRAtopicWeek on device-detected AF How to manage device-detected AF? Anticoagulation prevents some strokes and in…
RT @EHRAPresident: The #EHRAtopicWeek on device-detected AF How to manage device-detected AF? Anticoagulation prevents some strokes and in…
RT @EHRAPresident: The #EHRAtopicWeek on device-detected AF How to manage device-detected AF? Anticoagulation prevents some strokes and in…
The #EHRAtopicWeek on device-detected AF How to manage device-detected AF? Anticoagulation prevents some strokes and increases major but non-lethal bleeding
Letter by Aldaas et al Regarding Article, "Direct Oral Anticoagulants for Stroke Prevention in Patients With Device-Detected Atrial Fibrillation: A Study-Level Meta-Analysis of the NOAH-AFNET 6 and ARTESiA Trials" https://t.co/lsXEPey0Mg
RT @UCSDCardiology: New publication
New publication
RT @JimSiegler: @JAHA_AHA @afnet_ev @emilycob In part because of NOAH AFNET-6 and the meta-analysis with ARTESIA (https://t.co/Aw2BHj2gGV),…
@JAHA_AHA @afnet_ev @emilycob In part because of NOAH AFNET-6 and the meta-analysis with ARTESIA (https://t.co/Aw2BHj2gGV), we now know these brief AHREs are not benign and can be treated with AC. 4/4
Anticoagulación oral con edoxaban o apixaban reduce el riesgo de ictus en pacientes con fibrilación auricular subclínica o los episodios de alta frecuencia auricular y aumenta el riesgo de sangrado mayor #DOACs #stroke #AF #device https://t.co/td5HcFNyXj
@figueiredo_ep @JACCJournals @ehj_ed No direct comparison, just some speculations on the trial design and consequent results. However, both trials point in the same direction overall! https://t.co/HyLFRhZFiD
Direct Oral Anticoagulants for Stroke Prevention in Patients With Device-Detected Atrial Fibrillation: A Study-Level Meta-Analysis of the NOAH-AFNET 6 and ARTESiA Trials https://t.co/Jyz4bE7LM0 https://t.co/XuVRFxe8d5
RT @SidPatelMD:
RT @SidPatelMD:
RT @SidPatelMD:
RT @SidPatelMD:
RT @SidPatelMD:
RT @SidPatelMD:
Reducción de riesgo tromboembolico con aumento de sangrado. ACO en FA subclínica sigue siendo tema no resuelto. DOAC for Stroke Prevention in Patients With Device-Detected Atrial Fibrillation: Meta-Analysis of the NOAH-AFNET 6 and ARTESiA Trials https://t.co/GrRgs8yrwv
Direct Oral Anticoagulants for Stroke Prevention in Patients with Device-Detected Atrial Fibrillation: A Study-Level Meta-Analysis of the NOAH-AFNET 6 and ARTESiA Trials | Circulation https://t.co/YalK0knyoC
Direct Oral Anticoagulants for Stroke Prevention in Patients with Device-Detected Atrial Fibrillation: A Study-Level Meta-Analysis of the NOAH-AFNET 6 and ARTESiA Trials | Circulation https://t.co/2pra7uKwSV
Direct Oral Anticoagulants for Stroke Prevention in Patients with Device-Detected Atrial Fibrillation: A Study-Level Meta-Analysis of the NOAH-AFNET 6 and ARTESiA Trials | Circulation https://t.co/15CC5hYoQH
【メタアナリシス】デバイスで検出された心房細動患者における脳卒中予防のためのDOAC(経口抗凝固薬は虚血性脳卒中を減少させた一方、大出血を増加させた。) #ペ読 https://t.co/tzqgcyXNeq
RT @rui_providencia: Direct Oral Anticoagulants for Stroke Prevention in Patients with Device-Detected Atrial Fibrillation: A Study-Level M…
Direct Oral Anticoagulants for Stroke Prevention in Patients with Device-Detected Atrial Fibrillation: A Study-Level Meta-Analysis of the NOAH-AFNET 6 and ARTESiA Trials | Circulation https://t.co/1xWmNEY32l
RT @joselmerino: Meta-Analysis of the NOAH-AFNET & ARTESiA Trials. Results are consistent: OAC with edoxaban or apixaban reduces the risk o…
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
RT @DrJasonAndrade: And right on time is the meta-analysis from @WFMMD et al. Significant stroke reduction with no impact on mortality.…
RT @joselmerino: Meta-Analysis of the NOAH-AFNET & ARTESiA Trials. Results are consistent: OAC with edoxaban or apixaban reduces the risk o…
RT @joselmerino: Meta-Analysis of the NOAH-AFNET & ARTESiA Trials. Results are consistent: OAC with edoxaban or apixaban reduces the risk o…
@leftbundle @Ed_Gerst Just saw this meta-analysis combining both trials but not sure if it answers the threshold question https://t.co/8sXGCmLBL1
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
総死亡は1.1%の増加傾向。 https://t.co/Gj7Q4ef2p2
RT @joselmerino: Meta-Analysis of the NOAH-AFNET & ARTESiA Trials. Results are consistent: OAC with edoxaban or apixaban reduces the risk o…
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
@Ed_Gerst https://t.co/izeZLTSkhJ
RT @rui_providencia: Direct Oral Anticoagulants for Stroke Prevention in Patients with Device-Detected Atrial Fibrillation: A Study-Level M…
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
RT @marcovitoloMD:
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
https://t.co/XA4SkPQkXw
RT @DrJasonAndrade: And right on time is the meta-analysis from @WFMMD et al. Significant stroke reduction with no impact on mortality.…
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
Meta-Analysis of the NOAH-AFNET & ARTESiA Trials. Results are consistent: OAC with edoxaban or apixaban reduces the risk of stroke in patients with device-detected AF and increases the risk of major bleeding. https://t.co/2HsxJwxH5A (Stroke, Syst Embolism, MI, PE, CV Death) https://t.co/uzpNIt7YQA
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
RT @DrJasonAndrade: And right on time is the meta-analysis from @WFMMD et al. Significant stroke reduction with no impact on mortality.…
RT @marcovitoloMD:
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
RT @marcovitoloMD:
RT @CircAHA: #JustPublished #AHA23 #CIRCAHA23 In a meta analysis of 2 RCTS, DOAC use for device detected #AF was associated with⬇️risk of t…
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
RT @DrJasonAndrade: And right on time is the meta-analysis from @WFMMD et al. Significant stroke reduction with no impact on mortality.…
RT @CircAHA: #JustPublished #AHA23 #CIRCAHA23 In a meta analysis of 2 RCTS, DOAC use for device detected #AF was associated with⬇️risk of t…
RT @CircAHA: #JustPublished #AHA23 #CIRCAHA23 In a meta analysis of 2 RCTS, DOAC use for device detected #AF was associated with⬇️risk of t…
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
RT @rui_providencia: Direct Oral Anticoagulants for Stroke Prevention in Patients with Device-Detected Atrial Fibrillation: A Study-Level M…
RT @marcovitoloMD:
Direct Oral Anticoagulants for Stroke Prevention in Patients with Device-Detected Atrial Fibrillation: A Study-Level Meta-Analysis of the NOAH-AFNET 6 and ARTESiA Trials #AHA23 #afib #atrialfibrillation #highatrialrateepisodes #anticoagulation https://t.co/nO7mgRv55B
RT @DrJasonAndrade: And right on time is the meta-analysis from @WFMMD et al. Significant stroke reduction with no impact on mortality.…
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
¿Será que combinar dos bases de datos, una de un estudio negativo y otro positivo, lo podemos llamar meta-análisis? https://t.co/1Vnz8OCauM
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
RT @marcovitoloMD:
RT @marcovitoloMD:
RT @marcovitoloMD:
RT @DrJasonAndrade: And right on time is the meta-analysis from @WFMMD et al. Significant stroke reduction with no impact on mortality.…
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
RT @WFMMD: @kaulcsmc This meta-analysis should help you reconcile ARTESiA and NOAH. They are consistent: https://t.co/lOb1IxtaB3
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
RT @StephanSchirme2: @gunnar_heine @jongichun @BorisSchmidt5 @IngoEitel @floriancustodis @nervensystemck the meta-analysis might help: http…
@gunnar_heine @jongichun @BorisSchmidt5 @IngoEitel @floriancustodis @nervensystemck the meta-analysis might help: https://t.co/36IX6aPYHB
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
RT @DrJasonAndrade: And right on time is the meta-analysis from @WFMMD et al. Significant stroke reduction with no impact on mortality.…
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
And right on time is the meta-analysis from @WFMMD et al. Significant stroke reduction with no impact on mortality. https://t.co/KfLD0HLDBZ https://t.co/Fv5nj56OHW
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
RT @CircAHA: #JustPublished #AHA23 #CIRCAHA23 In a meta analysis of 2 RCTS, DOAC use for device detected #AF was associated with⬇️risk of t…
RT @CircAHA: #JustPublished #AHA23 #CIRCAHA23 In a meta analysis of 2 RCTS, DOAC use for device detected #AF was associated with⬇️risk of t…
RT @CircAHA: #JustPublished #AHA23 #CIRCAHA23 In a meta analysis of 2 RCTS, DOAC use for device detected #AF was associated with⬇️risk of t…
@kaulcsmc This meta-analysis should help you reconcile ARTESiA and NOAH. They are consistent: https://t.co/lOb1IxtaB3
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
RT @CircAHA: #JustPublished #AHA23 #CIRCAHA23 In a meta analysis of 2 RCTS, DOAC use for device detected #AF was associated with⬇️risk of t…
@edurontoFF @SAC_54 @ComunidadFAC @SIAC_cardio This meta-analysis should help you reconcile ARTESiA and NOAH. They are consistent: https://t.co/lOb1IxtaB3
@Geno_shun This meta-analysis should help you reconcile ARTESiA and NOAH. They are consistent: https://t.co/lOb1IxtaB3
@gonzaeperez @jpcostabel @adribaran @SposatoL @edurontoFF @AHAScience @SIAC_cardio @ElectroSIAC1 @LAHRSonline1 @DrMarthaGulati @mmamas1973 @ErinMichos @mariofitzm @rigotordoc This meta-analysis should help you reconcile ARTESiA and NOAH. They are consistent: https://t.co/lOb1IxtaB3
#JustPublished #AHA23 #CIRCAHA23 In a meta analysis of 2 RCTS, DOAC use for device detected #AF was associated with⬇️risk of the composite of CV death, stroke, PE, arterial embolism and MI but⬆️risk of major bleeding @AlexanderPBenz @WFMMD #AHAJournals https://t.co/22f8nEdzgm
RT @WFMMD: With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev…
With @ARTESIA_RCT presented at #AHA23 this AM, many are working to reconcile the positive results with those from NOAH @afnet_ev 6 from #ESC2023. This meta-analysis does just that. The trials are totally consistent: https://t.co/lOb1IxtaB3 #EPeeps