PubHawk
December 2023 PMID 37957359

Refeeding-associated AMPK complex activity is a hallmark of health and longevity.

Roberto Ripa, Eugen Ballhysa, Joachim D Steiner, Raymond Laboy, Andrea Annibal, Nadine Hochhard, Christian Latza, Luca Dolfi, Chiara Calabrese, Anna M Meyer, Maria Cristina Polidori, Roman-Ulrich Müller, Adam Antebi

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Mentions

36
Peak: 2 in Nov 2023
across 5 sources since Nov 2023

Extended reach

5,262
potential audience

Total likes

146

Video views

2,774

Mentions per month

Nov 2023 – Aug 2025

Where it's discussed

  • News26 articles
  • YouTube3 videos
  • Facebook3 posts
  • X / Twitter2 posts
  • Reddit2 posts

AI synopsis

What people are saying

Discussions highlight the importance of AMPK activity as a hallmark of health, with comments emphasizing its role in longevity and the potential for targeting this pathway. The tone is positive and curious, reflecting genuine interest in the scientific implications, such as references to gene expression and metabolic health, which demonstrate thoughtful engagement.

AgreementModerate agreement

Most discussions acknowledge the significance of AMPK activity in relation to health and longevity, with some outright endorsing the findings.

InterestHigh interest

The topic attracts strong interest, as indicated by enthusiasm and curiosity expressed in the comments.

EngagementModerate engagement

Participants refer to specific aspects like the refeeding process and gene activity, showing moderate depth in their discussion.

ImpactModerate impact

While some see the research as promising, the overall discourse suggests a recognition of its potential influence but not immediate widespread impact.

Abstract in brief

  • Late-life dietary changes have limited success in improving longevity and reducing frailty, and researchers examined the fasting response in aging killifish to understand why.
  • A study found that older fish have a fasting-like metabolic state that is influenced by changes in gene expression, specifically involving AMPK regulatory subunits.
  • Transgenic fish that maintained higher levels of AMPK showed better metabolic health and prolonged lifespan, suggesting that targeting AMPK activation could help mitigate age-related health decline in humans too.
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Top posts

Most liked on X and Bluesky
Adipose Papers
@adipose_papers · X

Refeeding-associated AMPKγ1 complex activity is a hallmark of health and longevity https://t.co/88mHWVfscW https://t.co/Pk2ohnxsPh

Nov 14, 2023 · 2,445 followers View post →
evomorphpapers
@evomorph_papers · X

Refeeding-associated AMPKγ1 complex activity is a hallmark of health and longevity https://t.co/voFm86bsPB

Nov 14, 2023 · 44 followers View post →

All mentions

evomorphpapers
@evomorph_papers · X

Refeeding-associated AMPKγ1 complex activity is a hallmark of health and longevity https://t.co/voFm86bsPB

Nov 14, 2023 · 44 followers View post →
Adipose Papers
@adipose_papers · X

Refeeding-associated AMPKγ1 complex activity is a hallmark of health and longevity https://t.co/88mHWVfscW https://t.co/Pk2ohnxsPh

Nov 14, 2023 · 2,445 followers View post →