PubHawk
December 2023 PMID 38036944

Gut microbiota induces weight gain and inflammation in the gut and adipose tissue independent of manipulations in diet, genetics, and immune development.

Devesha H Kulkarni, Brigida Rusconi, Alexandria N Floyd, Elisabeth L Joyce, Khushi B Talati, Hrishi Kousik, Dereck Alleyne, Dalia L Harris, Lorena Garnica, Ryan McDonough, Shay S Bidani, Hrishikesh S Kulkarni, Elizabeth P Newberry, Keely G McDonald, Rodney D Newberry

Download social card

Mentions

5
Peak: 3 in Dec 2023
across 2 sources since Dec 2023

Extended reach

17,533
potential audience

Total likes

41

Video views

1,401

Mentions per month

Dec 2023 – Feb 2025

Where it's discussed

  • X / Twitter3 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussions reflect strong agreement with the publication, particularly as they question traditional calorie-focused models like CICO, with phrases such as 'futility' and 'sufficient to induce weight gain' expressing skepticism about diet and genetics alone. The tone conveys curiosity and concern about how these findings impact current approaches to obesity, with participants engaging deeply in debating the study's implications for science and health policies.

AgreementStrong agreement

All discussions strongly support the findings of the publication, emphasizing its significance in shifting understanding of obesity causes.

InterestModerate interest

Posts demonstrate a moderate level of curiosity, particularly concerning the implications for current nutritional and medical paradigms.

EngagementModerate engagement

Participants engage by highlighting the study's challenge to established hypotheses and discussing its broader scientific relevance.

ImpactHigh impact

The discussions suggest the research could significantly influence future research directions and public health strategies.

Abstract in brief

  • The study shows that the gut microbiota from obese humans can cause weight gain and inflammation in mice, even without changes in diet or genetics.
  • The obese microbiota leads to increased fat and intestinal inflammation but doesn't cause leaks in the gut barrier or significantly boost immune responses in the gut.
  • These findings suggest that gut microbes alone can drive obesity and related inflammation independently of other factors like diet, genetics, or immune system development.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Thomas P Seager, PhD
@seagertp · X

More evidence of the futility of the calories-in-calories-out (CICO) hypothesis: "Human obese gut microbiota is sufficient to induce weight gain & inflammation" https://t.co/jPeVmCBDW9 https://t.co/Q0RwWhaNPQ

Dec 7, 2023 · 2 likes · 13,164 followers View post →
Adipose Papers
@adipose_papers · X

Gut microbiota induces weight gain and inflammation in the gut and adipose tissue independent of manipulations in diet, genetics, and immune development https://t.co/godgmwW6o8 https://t.co/GouybPvzt0

Dec 1, 2023 · 2,475 followers View post →

All mentions

Thomas P Seager, PhD
@seagertp · X

More evidence of the futility of the calories-in-calories-out (CICO) hypothesis: "Human obese gut microbiota is sufficient to induce weight gain & inflammation" https://t.co/jPeVmCBDW9 https://t.co/Q0RwWhaNPQ

Dec 7, 2023 · 2 likes · 13,164 followers View post →
Sáfárné Hatrágyi Henrietta
@HatragyiSafarne · X

Gut microbiota induces weight gain and inflammation in the gut and adipose tissue independent of manipulations in diet, genetics, and immune development.

Dec 1, 2023 · 494 followers View post →
Adipose Papers
@adipose_papers · X

Gut microbiota induces weight gain and inflammation in the gut and adipose tissue independent of manipulations in diet, genetics, and immune development https://t.co/godgmwW6o8 https://t.co/GouybPvzt0

Dec 1, 2023 · 2,475 followers View post →