Cell Rep December 2023 PMID 38052211

Whole-brain mapping reveals the divergent impact of ketamine on the dopamine system.

Malika S Datta, Yannan Chen, Shradha Chauhan, Jing Zhang, Estanislao Daniel De La Cruz, Cheng Gong, Raju Tomer

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Peak: 10 in Apr 2023

across 5 sources since Apr 2023

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Apr 2023 – Jan 2024

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What people are saying

Discussions generally recognize the importance of the findings, such as references to the divergent effects on dopamine and neural plasticity, with some posts sharing the study source. The tone suggests curiosity and an appreciation for the potential implications, as evidenced by phrases like 'diverse impacts' and mentions of 'brain networks,' indicating deeper engagement and perceived significance.

AgreementModerate agreement

Most discussions acknowledge the significance of the study, with some explicitly supporting its findings on ketamine's neural impact.

InterestModerate interest

Participants show moderate curiosity, often engaging with the relevance of brain mapping and its implications for understanding ketamine's effects.

EngagementModerate engagement

Many discussions reference specific details like dopamine systems and brain regions, indicating a fair level of thoughtful engagement.

ImpactModerate impact

The conversations imply that the study could influence future research and understanding of neural plasticity related to ketamine use, suggesting a positive perception of its importance.

Abstract in brief

Wholebrain mapping shows that repeated ketamine use affects various brain regions, decreasing dopamine neurons linked to behavior and increasing activity in the hypothalamus.
The study highlights diverse changes in long-range brain connections, especially in areas like the prefrontal cortex, striatum, and sensory regions.
It suggests that posttranscriptional regulation (a layer of gene expression control) may play a role in how ketamine induces neural plasticity and reshapes brain networks with repeated use.]

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Impact of Ketamine on Brain Dopamine System Revealed by Whole-brain Mapping

Whole-brain mapping shows that repeated ketamine use affects various brain regions, decreasing dopamine neurons linked to behavior and increasing activity in the hypothalamus. The study highlights diverse changes in…

Science Beta · Dec 6, 2023 33 views

Kawa

@iamnotkawa · X

https://t.co/bykDZUVurr Whole-brain mapping reveals the divergent impact of ketamine on the dopamine system

Jan 16, 2024 · 285 followers View post →

Roger Blackwell

@rogerablackwell · X

Whole-brain mapping reveals the divergent impact of ketamine on the dopamine system https://t.co/VADhW7NGKB

Dec 10, 2023 · 2,304 followers View post →

な bot

@NeuroNNNNN_bot · X

[Cell Rep.] Whole-brain mapping reveals the divergent impact of ketamine on the dopamine system https://t.co/HHZV5S92Q5

Dec 6, 2023 · 26 followers View post →

Pratik Sen

@pratsen · X

Whole-brain mapping reveals the divergent impact of ketamine on the dopamine system: Cell Reports https://t.co/tycUpgcMxg

Dec 5, 2023 · 1 like · 38 followers View post →

BryanRoth

@zenbrainest · X

Whole-brain mapping reveals the divergent impact of ketamine on the dopamine system: Cell Reports https://t.co/Yx4953Sq0K

Dec 5, 2023 · 32 likes · 17,003 followers View post →

Awaken The “I AM” | r/microdosing | Mush Love

@LiveInMushLove · X

RT @blossomact: Whole-brain mapping reveals the divergent impact of ketamine on the dopamine system https://t.co/fboL8wRGfz https://t.co/vt…

Apr 26, 2023 · 1 share · 728 followers View post →

Blossom

@blossomact · X

Whole-brain mapping reveals the divergent impact of ketamine on the dopamine system https://t.co/fboL8wRGfz https://t.co/vtvLn35HoV

Apr 26, 2023 · 2 likes · 1 share · 3,361 followers View post →

Oliver Miller

@OliverHMiller · X

RT @biorxiv_neursci: Whole-brain mapping reveals the divergent impact of ketamine on the dopamine system https://t.co/vWtdBtxny1 #biorxiv_…

Apr 13, 2023 · 5 shares · 842 followers View post →

htw

@heniek_htw · X

Whole-#brain mapping reveals the divergent impact of #ketamine on the #dopamine system https://t.co/CADfi3g0t0 https://t.co/tmm9sOjwES

Apr 13, 2023 · 7 likes · 11,281 followers View post →

Staci Thornton

@snthornton29 · X

RT @biorxiv_neursci: Whole-brain mapping reveals the divergent impact of ketamine on the dopamine system https://t.co/vWtdBtxny1 #biorxiv_…

Apr 13, 2023 · 5 shares · 488 followers View post →

Pratik Sen

@pratsen · X

RT @biorxiv_neursci: Whole-brain mapping reveals the divergent impact of ketamine on the dopamine system https://t.co/vWtdBtxny1 #biorxiv_…

Apr 12, 2023 · 5 shares · 38 followers View post →

yoshiyuki nishio

@nishiokov · X

RT @biorxiv_neursci: Whole-brain mapping reveals the divergent impact of ketamine on the dopamine system https://t.co/vWtdBtxny1 #biorxiv_…

Apr 12, 2023 · 5 shares · 512 followers View post →

qicy

@qicy11 · X

RT @biorxiv_neursci: Whole-brain mapping reveals the divergent impact of ketamine on the dopamine system https://t.co/vWtdBtxny1 #biorxiv_…

Apr 12, 2023 · 5 shares · 381 followers View post →

bioRxiv Neuroscience

@biorxiv_neursci · X

Whole-brain mapping reveals the divergent impact of ketamine on the dopamine system https://t.co/vWtdBtxny1 #biorxiv_neursci

Apr 12, 2023 · 31 likes · 5 shares · 59,857 followers View post →

bioRxiv

@biorxivpreprint · X

Whole-brain mapping reveals the divergent impact of ketamine on the dopamine system https://t.co/CPq1NvU0Xh #bioRxiv

Apr 12, 2023 · 136,987 followers View post →

Whole-brain mapping reveals the divergent impact of ketamine on the dopamine system.

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Impact of Ketamine on Brain Dopamine System Revealed by Whole-brain Mapping