PubHawk
Mol Nutr Food Res February 2024 PMID 38054637

A High MCT-Based Ketogenic Diet Suppresses Th1 and Th17 Responses to Ameliorate Experimental Autoimmune Encephalomyelitis in Mice by Inhibiting GSDMD and JAK2-STAT3/4 Pathways.

Qianye Zhang, Wei Sun, Qingpeng Wang, Xuexing Zheng, Ruiyan Zhang, Ning Zhang

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Mentions

24
Peak: 20 in Dec 2023
across 5 sources since Dec 2023

Extended reach

480,605
potential audience

Total likes

69

Video views

440

Mentions per month

Dec 2023 – Jan 2025

Where it's discussed

  • X / Twitter19 posts
  • YouTube2 videos
  • Bluesky1 posts
  • Reddit1 posts
  • Blogs1 articles

AI synopsis

What people are saying

Across the discussions, there is notable support for the research, with slogans like 'ketogenic diet cures multiple sclerosis' and detailed mentions of pathways like GSDMD and JAK2-STAT3/4. The tone is enthusiastic and confident, emphasizing the potential for new treatments, which accounts for the high scores in agreement and impact. The use of scientific terms indicates a willingness to engage deeply with the research findings.

AgreementStrong agreement

Most discussions strongly endorse the research, emphasizing its therapeutic potential for multiple sclerosis and autoimmune conditions.

InterestHigh interest

Users display high curiosity about the ketogenic diet’s effects, with phrases like 'cures' and 'promising' indicating strong interest.

EngagementModerate engagement

The discussions include specific references to scientific pathways and applications, showing moderate to deep engagement.

ImpactHigh impact

The widespread sharing and emphasis on potential cures suggest these discussions view the research as highly impactful.

Abstract in brief

  • The ketogenic diet (KD) shows promise as a treatment for multiple sclerosis by reducing brain damage, immune cell activation, and inflammation in a mouse model of the disease.
  • KD works by decreasing harmful immune responses (Th1 and Th17) and increasing protective responses (Th2 and Treg), while also inhibiting key inflammatory pathways (GSDMD and JAK2/STAT3/4).
  • These findings suggest that KD could be an effective strategy to prevent immune cell infiltration into the central nervous system and may offer new avenues for MS therapy.]
Read the full abstract

Top posts

Most liked on X and Bluesky
J P Fanton
@HealthyFellow · X

A High #MCT-Based #Ketogenic #Diet Suppresses Th1 & Th17 Responses to Ameliorate Experimental #Autoimmune #Encephalomyelitis in Mice by Inhibiting GSDMD & JAK2-STAT3/4 Pathways https://t.co/D3Z6yOPkzw @_atanas_ @_INPST @ScienceCommuni2 @DHPSP @MEATritionCom @shashiiyengar https://t.co/HHkdATm8Fo

Dec 6, 2023 · 23 likes · 10 shares · 26,007 followers View post →
Dr. Thomas Ichim
@exosome · X

There you have it folks.... #ketogenic diet cures #MultipleSclerosis ?? https://t.co/x7jr2vi71o

Dec 8, 2023 · 22 likes · 6 shares · 35,052 followers View post →
Atanas G. Atanasov
@_atanas_ · X

RT @HealthyFellow: A High #MCT-Based #Ketogenic #Diet Suppresses Th1 & Th17 Responses to Ameliorate Experimental #Autoimmune #Encephalomyel…

Dec 14, 2023 · 10 shares · 124,408 followers View post →
Robb Wolf
@robbwolf · X

RT @HealthyFellow: A High #MCT-Based #Ketogenic #Diet Suppresses Th1 & Th17 Responses to Ameliorate Experimental #Autoimmune #Encephalomyel…

Dec 6, 2023 · 10 shares · 121,748 followers View post →
TheHealthyRD
@HeidiHmoretti · X

RT @HealthyFellow: A High #MCT-Based #Ketogenic #Diet Suppresses Th1 & Th17 Responses to Ameliorate Experimental #Autoimmune #Encephalomyel…

Dec 7, 2023 · 10 shares · 74,963 followers View post →
Dr. Thomas Ichim
@exosome · X

RT @exosome: There you have it folks.... #ketogenic diet cures #MultipleSclerosis ?? https://t.co/x7jr2vi71o

Dec 9, 2023 · 6 shares · 35,052 followers View post →

All mentions

Atanas G. Atanasov
@_atanas_ · X

RT @HealthyFellow: A High #MCT-Based #Ketogenic #Diet Suppresses Th1 & Th17 Responses to Ameliorate Experimental #Autoimmune #Encephalomyel…

Dec 14, 2023 · 10 shares · 124,408 followers View post →
Science Communication
@ScienceCommuni2 · X

RT @HealthyFellow: A High #MCT-Based #Ketogenic #Diet Suppresses Th1 & Th17 Responses to Ameliorate Experimental #Autoimmune #Encephalomyel…

Dec 14, 2023 · 10 shares · 2,890 followers View post →
International Natural Product Sciences Taskforce
@_INPST · X

RT @HealthyFellow: A High #MCT-Based #Ketogenic #Diet Suppresses Th1 & Th17 Responses to Ameliorate Experimental #Autoimmune #Encephalomyel…

Dec 14, 2023 · 10 shares · 10,290 followers View post →
Dr. Thomas Ichim
@exosome · X

RT @exosome: There you have it folks.... #ketogenic diet cures #MultipleSclerosis ?? https://t.co/x7jr2vi71o

Dec 9, 2023 · 6 shares · 35,052 followers View post →
JHod
@jhod · X

RT @exosome: There you have it folks.... #ketogenic diet cures #MultipleSclerosis ?? https://t.co/x7jr2vi71o

Dec 9, 2023 · 6 shares · 836 followers View post →
DesignedByNature
@DesignedNature · X

RT @KetosisJournal: #TheJournalOfKetosis "A High MCT-Based Ketogenic Diet Suppresses Th1 and Th17 Responses to Ameliorate Experimental Auto…

Dec 9, 2023 · 1 share · 438 followers View post →
TheJournalOfKetosis
@KetosisJournal · X

#TheJournalOfKetosis "A High MCT-Based Ketogenic Diet Suppresses Th1 and Th17 Responses to Ameliorate Experimental Autoimmune Encephalomyelitis in Mice by Inhibiting GSDMD and JAK2-STAT3/4 Pathways. (Pub Date: 2023-12-06)" https://t.co/qvb5YaIbi7

Dec 9, 2023 · 1 share · 91 followers View post →
Longevity Explorer
@LongevityExplor · X

RT @exosome: There you have it folks.... #ketogenic diet cures #MultipleSclerosis ?? https://t.co/x7jr2vi71o

Dec 9, 2023 · 6 shares · 1,670 followers View post →
P123
@P1231032850 · X

RT @exosome: There you have it folks.... #ketogenic diet cures #MultipleSclerosis ?? https://t.co/x7jr2vi71o

Dec 9, 2023 · 6 shares · 3,411 followers View post →
RINO Rooter
@RinoRooter · X

RT @exosome: There you have it folks.... #ketogenic diet cures #MultipleSclerosis ?? https://t.co/x7jr2vi71o

Dec 9, 2023 · 6 shares · 6,596 followers View post →
Frank Paul Mora
@InTime_49 · X

RT @exosome: There you have it folks.... #ketogenic diet cures #MultipleSclerosis ?? https://t.co/x7jr2vi71o

Dec 8, 2023 · 6 shares · 430 followers View post →
Dr. Thomas Ichim
@exosome · X

There you have it folks.... #ketogenic diet cures #MultipleSclerosis ?? https://t.co/x7jr2vi71o

Dec 8, 2023 · 22 likes · 6 shares · 35,052 followers View post →
TheHealthyRD
@HeidiHmoretti · X

RT @HealthyFellow: A High #MCT-Based #Ketogenic #Diet Suppresses Th1 & Th17 Responses to Ameliorate Experimental #Autoimmune #Encephalomyel…

Dec 7, 2023 · 10 shares · 74,963 followers View post →
Frederic Danel
@Frederic_Danel · X

RT @HealthyFellow: A High #MCT-Based #Ketogenic #Diet Suppresses Th1 & Th17 Responses to Ameliorate Experimental #Autoimmune #Encephalomyel…

Dec 7, 2023 · 10 shares · 333 followers View post →
MEATrition.com
@MEATritionCom · X

RT @HealthyFellow: A High #MCT-Based #Ketogenic #Diet Suppresses Th1 & Th17 Responses to Ameliorate Experimental #Autoimmune #Encephalomyel…

Dec 7, 2023 · 10 shares · 6,368 followers View post →
AngryPhDstudent❗️❗️❗️
@ONNESHA092 · X

RT @HealthyFellow: A High #MCT-Based #Ketogenic #Diet Suppresses Th1 & Th17 Responses to Ameliorate Experimental #Autoimmune #Encephalomyel…

Dec 7, 2023 · 10 shares · 203 followers View post →
Shashi Iyengar | Metabolic Health India®
@shashiiyengar · X

RT @HealthyFellow: A High #MCT-Based #Ketogenic #Diet Suppresses Th1 & Th17 Responses to Ameliorate Experimental #Autoimmune #Encephalomyel…

Dec 6, 2023 · 10 shares · 29,072 followers View post →
Robb Wolf
@robbwolf · X

RT @HealthyFellow: A High #MCT-Based #Ketogenic #Diet Suppresses Th1 & Th17 Responses to Ameliorate Experimental #Autoimmune #Encephalomyel…

Dec 6, 2023 · 10 shares · 121,748 followers View post →
J P Fanton
@HealthyFellow · X

A High #MCT-Based #Ketogenic #Diet Suppresses Th1 & Th17 Responses to Ameliorate Experimental #Autoimmune #Encephalomyelitis in Mice by Inhibiting GSDMD & JAK2-STAT3/4 Pathways https://t.co/D3Z6yOPkzw @_atanas_ @_INPST @ScienceCommuni2 @DHPSP @MEATritionCom @shashiiyengar https://t.co/HHkdATm8Fo

Dec 6, 2023 · 23 likes · 10 shares · 26,007 followers View post →
Gregory MS
@gregory-ms.com · Bluesky

https://gregory-ms.com/articles/172770/ A High MCT-Based Ketogenic Diet Suppresses Th1 and Th17 Responses to Ameliorate Experimental Autoimmune Encephalomyelitis in Mice by Inhibiting GSDMD and JAK2-STAT3/4 Pathways #MSchat #Neurology #MultipleSclerosis #NeuroSky #NeuroSkyence

Dec 6, 2023 View post →
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