Efficacy and safety of a 4-week course of repeated subcutaneous ketamine injections for treatment-resistant depression (KADS study): randomised double-blind active-controlled trial.
Discussions showcase a strong interest and deep engagement with the research, as evidenced by phrases like 'ketamine wins big' and references to specific trial results such as remission rates, indicating enthusiasm for the potential of ketamine as an effective treatment. The tone and context reflect a recognition of the study's importance, with many emphasizing its promising results and possible influence on future depression therapies.
AgreementModerate agreement
Most discussions support the findings of the study, emphasizing its positive results and potential clinical implications, evidenced by comments like 'Ketamine Wins Big' and mentions of promising trial outcomes.
InterestHigh interest
There is a high level of curiosity, as participants refer to multiple studies, dosing details, and comparisons to existing treatments, indicating they find the research relevant and worth exploring.
EngagementHigh engagement
Many discussions delve into details about the methodology and implications, with references to specific trial results and citations, showing deep involvement in understanding the topic.
ImpactHigh impact
Several posts highlight the trial’s significance, considering it a potential breakthrough in treating resistant depression and calling it a 'game changer,' thus perceiving high impact on mental health treatments.
Abstract in brief
The study tested the safety and effectiveness of a 4-week course of repeated subcutaneous racemic ketamine injections for treatment-resistant depression, comparing fixed and flexible dosing to midazolam as a control.
Results showed that flexible-dose ketamine was significantly more effective than midazolam in inducing remission of depression, while fixed-dose ketamine did not show a significant difference.
The treatment was generally safe and well tolerated, with manageable side effects like temporary blood pressure increases and psychotomimetic effects, indicating that subcutaneous ketamine could be a practical option for managing treatment-resistant depression.]
Pretty interesting RCT on ketamine for treatment-resistant depression - no benefit for low doses, but a revised dosing schedule with up to 2x the dose showed a fairly large improvement https://t.co/nh4fnmsKqo
⭐ In case you missed it: Generic #ketamine was confirmed to be an effective #antidepressant in people with treatment-resistant #depression.
An Australian, @NHMRC-funded, phase 3 trial by @UNSW @georgeinstitute @blackdoginst et al.
Researchers in Australia Demonstrate Efficacy of Ketamine for Treatment-Resistant Depression Over a 4-week Treatment Course
"..the proportional increase in remission comparing favourably to that of studies of intranasal esketamine.."
https://t.co/Dbeyza12u8
@7NewsMelbourne Why say its linked to mental illness?
We are currently using it in trials to treat resistant depression: https://t.co/tK3RsodvPM
There are a good number of studies showing that it has positive effects on mental illness.
https://t.co/tK3RsodvPM
https://t.co/3FA5ANQJO9
Jan 7, 2024 · 4 likes · 1 share · 1,241 followersView post →
BJ
BJPsych Journals
@TheBJPsych · X
#BJPsych Most Downloaded goes to ‘Efficacy and safety of a 4-week course of repeated subcutaneous ketamine injections for treatment-resistant depression (KADS study): randomised double-blind active-controlled trial’ by Colleen Loo et al
Read the article: https://t.co/sWyOA1HTiI https://t.co/j9uObxmFpv
Jun 17, 2024 · 2 likes · 13,386 followersView post →
TI
#TheSpiderHunter - Black History Is Important!
@Arthur59611540 · X
@Rahmami2585 @MaeWilbon @ChrisTurne83916 @drtessporess @YouTube Spravato vs. Seroquel: Ketamine Wins Big in Head-to-Head Depression Battle https://t.co/C4GFbFuzXh via @YouTube
Mar 1, 2024 · 2 likes · 4,119 followersView post →
Dr. Tracey Marks discusses ketamine's role in depression treatment, focusing on its mechanism as an NMDA receptor antagonist and neuroplasticity. The video compares FDA-approved Spravato with quetiapine and explores…
Recent research demonstrates the safety and efficacy of a 4-week course of subcutaneous ketamine injections, showing significant remission rates in treatment-resistant depression, with manageable side effects and…
#BJPsych Most Downloaded goes to ‘Efficacy and safety of a 4-week course of repeated subcutaneous ketamine injections for treatment-resistant depression (KADS study): randomised double-blind active-controlled trial’ by Colleen Loo et al
Read the article: https://t.co/sWyOA1HTiI https://t.co/j9uObxmFpv
Jun 17, 2024 · 2 likes · 13,386 followersView post →
F
ForensicPsyMD
@ForensicPsyMD · X
Efficacy and safety of a 4-week course of repeated subcutaneous ketamine injections for treatment-resistant depression (KADS study): randomised double-blind active-controlled trial | The British Journal of Psychiatry | Cambridge Core https://t.co/pmPHrC2NZV
@francoislegault @JustinTrudeau @POTUS @Eminem
Spravato vs. Seroquel: Ketamine Wins Big in Head-to-Head Depression Battle https://t.co/gdd1dg4qez via @YouTube Legalise heavy drugs
@Rahmami2585 @MaeWilbon @ChrisTurne83916 @drtessporess @YouTube Spravato vs. Seroquel: Ketamine Wins Big in Head-to-Head Depression Battle https://t.co/C4GFbFuzXh via @YouTube
Mar 1, 2024 · 2 likes · 4,119 followersView post →
A Phase III trial, found that a 4-week course of subcutaneous ketamine was more effective than midazolam in treating treatment-resistant depression, with a remission rate of 19.6% compared to 2.0% in the flexible-dose cohort.
https://t.co/WotnmNkIeX
Jan 10, 2024 · 2 likes · 3,029 followersView post →
RT @MarkHAnderson59: @7NewsMelbourne Why say its linked to mental illness?
We are currently using it in trials to treat resistant depress…
Jan 7, 2024 · 1 share · 1,241 followersView post →
MA
Mark Anderson
@MarkHAnderson59 · X
@7NewsMelbourne Why say its linked to mental illness?
We are currently using it in trials to treat resistant depression: https://t.co/tK3RsodvPM
There are a good number of studies showing that it has positive effects on mental illness.
https://t.co/tK3RsodvPM
https://t.co/3FA5ANQJO9
Jan 7, 2024 · 4 likes · 1 share · 1,241 followersView post →
P
P
@psychopharmacol · X
RCT: Twice-weekly SC racemic ketamine, 0.5–0.9 mg/kg, was more efficacious than midazolam after 4 weeks (remission rate - MADRS OR=12.1; 2.1–69.2), but not different when fixed doses of 0.5 mg(kg were used (1.3; 0.2–8.2). Ketamine was well tolerated https://t.co/BEzchHUsCP https://t.co/pVCoU8RG6s
This trial evaluated the acute efficacy and safety of a 4-week course of subcutaneous racemic ketamine in participants with TRD. https://t.co/ECHYYoiuNJ
Efficacy and safety of a 4-week course of repeated subcutaneous ketamine injections for treatment-resistant depression (KADS study): randomised double-blind active-controlled trial https://t.co/iuz9nEOzbo
New dog paper! Efficacy and safety of a 4-week course of repeated subcutaneous ketamine injections for treatment-resistant depression (KADS study): randomised double-blind active-controlled trial https://t.co/Cgxnz2u7TI
Efficacy and safety of a 4-week course of repeated subcutaneous ketamine injections for treatment-resistant depression (KADS study): randomised double-blind active-controlled trial https://t.co/XLg0IxUCmT
Efficacy and safety of a 4-week course of repeated subcutaneous ketamine injections for treatment-resistant depression (KADS study): randomised double-blind active-controlled trial https://t.co/7jgfdMPhMt
Promising results from @UNSW suggest that ketamine can be used as a new treatment option for severe treatment-resistant depression https://t.co/X1EU2a2shD
⭐ In case you missed it: Generic #ketamine was confirmed to be an effective #antidepressant in people with treatment-resistant #depression.
An Australian, @NHMRC-funded, phase 3 trial by @UNSW @georgeinstitute @blackdoginst et al.
Pretty interesting RCT on ketamine for treatment-resistant depression - no benefit for low doses, but a revised dosing schedule with up to 2x the dose showed a fairly large improvement https://t.co/nh4fnmsKqo
Researchers in Australia Demonstrate Efficacy of Ketamine for Treatment-Resistant Depression Over a 4-week Treatment Course
"..the proportional increase in remission comparing favourably to that of studies of intranasal esketamine.."
https://t.co/Dbeyza12u8
Study:
Efficacy and safety of a 4-week course of repeated subcutaneous ketamine injections for treatment-resistant depression (KADS study): randomised double-blind active-controlled trial
https://t.co/JAAdpcVibZ https://t.co/NwLbG7BSzN
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