Mol Cancer January 2024 PMID 38195537

Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and applications in cancer therapy.

Mohammad Chehelgerdi, Matin Chehelgerdi, Milad Khorramian-Ghahfarokhi, Marjan Shafieizadeh, Esmaeil Mahmoudi, Fatemeh Eskandari, Mohsen Rashidi, Asghar Arshi, Abbas Mokhtari-Farsani

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Mentions

Peak: 51 in Apr 2024

across 5 sources since Jan 2024

Extended reach

539,802

potential audience

Total likes

205

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1,805

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Jan 2024 – Oct 2025

Where it's discussed

X / Twitter64 posts
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AI synopsis

What people are saying

The overall discussions demonstrate appreciation for the review's detailed coverage of CRISPR mechanisms and challenges, with posts describing it as 'loading useful info' and 'great learning materials,' emphasizing educational value. The tone varies from enthusiasm about the technology's potential to curiosity about ongoing research, illustrating a balanced view of its transformative power and existing hurdles.

AgreementModerate agreement

Most discussions acknowledge the importance and potential of CRISPR in cancer therapy, supported by positive comments and references to its transformative capabilities.

InterestHigh interest

Posts frequently highlight the educational value and ongoing research, showing a strong curiosity and enthusiasm for the topic.

EngagementHigh engagement

Comments reflect a deep level of engagement, discussing specific mechanisms, research progress, and practical applications, indicating active interest.

ImpactModerate impact

While some recognize the significant influence of CRISPR on biomedical advances, others focus on ongoing challenges, leading to moderate impact perceptions.

Abstract in brief

The review explains how CRISPR is a powerful tool for editing genes, offering new ways to develop personalized cancer treatments by targeting mutations that cause tumors.
It covers various CRISPR-based strategies for cancer therapy, such as disabling tumor-promoting genes, boosting immune responses, fixing genetic mutations, and delivering cancer-killing agents directly to tumors, alongside current preclinical and clinical progress.
The review also highlights key challenges like off-target effects, safety concerns, and delivery methods, and discusses future research directions to overcome these barriers and fully harness CRISPR’s potential in cancer treatment.]

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All mentions

CRISPR Therapy for CPS1 Deficiency: A Breakthrough Case Study

A baby treated with CRISPR for CPS1 deficiency shows significant improvement. This video explores the innovative gene-editing therapy developed to address severe genetic disorders, highlighting its impact and the…

the bumbling biochemist · May 19, 2025 1,641 views

“CRISPR & Gene Editing: Rewriting the Code of Life”

Scio-Eureka · Oct 20, 2025 108 views

Advancing CAR T-Cell Therapy with CRISPR Gene Editing Techniques

CAR T cells are a groundbreaking personalized cancer treatment where synthetic receptors reprogram T cells to attack tumors. CRISPR-Cas9 gene editing offers new possibilities to improve therapy by precisely modifying T…

Nathan Markle · Oct 21, 2024 30 views

CRISPR Gene Editing in Cancer Therapy: Mechanisms and Challenges

This video explains how CRISPR is used for gene editing in cancer treatment, covering strategies like disabling tumor genes, enhancing immune responses, and delivering therapeutics. It highlights current progress…

Tuftcapstonegroup · Jul 18, 2025 26 views

Ian Hurn

@IanHurn0 · X

https://t.co/zhY9zNAVls https://t.co/lu3z4VFL7v

Aug 29, 2025 · 4,637 followers View post →

Ian Hurn

@IanHurn0 · X

Comprehensive review of CRISPR-Based Gene Editing: mechanisms, challenges, and applications in Cancer Therapy 9 January 2024 https://t.co/zhY9zNAnvU https://t.co/KcPj5Q4kRi

Aug 29, 2025 · 4,637 followers View post →

Ian Hurn

@IanHurn0 · X

Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and applications in cancer therapy January 2024 https://t.co/zhY9zNAnvU CRISPR-associated enzymes, such as Cas9, can be programmed to target specific DNA sequences, and when combined https://t.co/7ytsrYJwwC

Feb 20, 2025 · 4,637 followers View post →

waybe

@waybe201923114 · X

@AustereInfidel @jenniferzeng97 Is this it https://t.co/mEKRMa4f99.

Feb 15, 2025 · 104 followers View post →

Pratik

@pratiknsingh · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Sep 24, 2024 · 41 shares · 104 followers View post →

Nouf_Alaziz

@Nouf_Aldoweesh · X

RT @globalhealthexh: اكتشفوا كيف تساعد تقنية CRISPR على علاج السرطان من خلال استهداف جينات الورم وتعزيز الاستجابة المناعية وإصلاح الطفرات و…

Sep 6, 2024 · 1 share · 37 followers View post →

Global Health Exhibition - ملتقى الصحة العالمي

@globalhealthexh · X

اكتشفوا كيف تساعد تقنية CRISPR على علاج السرطان من خلال استهداف جينات الورم وتعزيز الاستجابة المناعية وإصلاح الطفرات وإيصال الجزيئات القاتلة للسرطان.

Sep 6, 2024 · 1 like · 1 share · 12,284 followers View post →

Miguel F. Segura

@MF_Segura · X

RT @SkodaLab: Talking about publishing practices today... How come that the prestigious Molecular Cancer @SN_Oncology (10th in Oncology, 4t…

Jul 2, 2024 · 2 shares · 247 followers View post →

Eva Fronkova

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RT @SkodaLab: Talking about publishing practices today... How come that the prestigious Molecular Cancer @SN_Oncology (10th in Oncology, 4t…

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Jan Škoda

@SkodaLab · X

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xd tan

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RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

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Johns Hopkins Frailty Science #FrailtyFighter

@FrailtyScience · X

RT @agingdoc1: Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and applications in cancer therapy https://t.co/…

Apr 8, 2024 · 4 shares · 2,269 followers View post →

Dr. Michael Zand

@michaelzand · X

RT @agingdoc1: Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and applications in cancer therapy https://t.co/…

Apr 6, 2024 · 4 shares · 3,780 followers View post →

john morley

@drjohnmorley · X

Chehelgerdi, M., Chehelgerdi, M., Khorramian-Ghahfarokhi, M. et al. Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and applications in cancer therapy. Mol Cancer 23, 9 (2024). https://t.co/w86NNx5Q7Z

Apr 6, 2024 · 2 likes · 8,324 followers View post →

Medical Advances

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RT @InnovOncology: Comprehensive review of #CRISPR-based gene editing: mechanisms, challenges, and applications in cancer therapy. #Oncolo…

Apr 6, 2024 · 4 shares · 29,871 followers View post →

John Greene

@Greene_Thoughts · X

RT @agingdoc1: Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and applications in cancer therapy https://t.co/…

Apr 6, 2024 · 4 shares · 1,670 followers View post →

Lisa Vlad

@LisaVlad2 · X

RT @agingdoc1: Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and applications in cancer therapy https://t.co/…

Apr 6, 2024 · 4 shares · 102 followers View post →

Agingdoc

@agingdoc1 · X

Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and applications in cancer therapy https://t.co/6m20RCYNFn https://t.co/LS676nQd4R

Apr 6, 2024 · 4 likes · 4 shares · 41,313 followers View post →

The Innovation | Medicine

@Innov_Medicine · X

RT @InnovOncology: Comprehensive review of #CRISPR-based gene editing: mechanisms, challenges, and applications in cancer therapy. #Oncolo…

Apr 6, 2024 · 4 shares · 253,995 followers View post →

Melinda L Tursky

@melinda_tursky · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 4, 2024 · 41 shares · 1,211 followers View post →

A/Prof Nik Veldhuis

@NikVeldhuis · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 4, 2024 · 41 shares · 767 followers View post →

Sylvia Le Dévédec

@seledevedec · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 4, 2024 · 41 shares · 441 followers View post →

ddhb

@ddhb80180543 · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 4, 2024 · 41 shares · 15 followers View post →

lino

@ljiqfb · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

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Szu Shuo Lee

@ShuoSzu · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 4, 2024 · 41 shares · 156 followers View post →

Han Yang

@HanYang_Henry · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 4, 2024 · 41 shares · 42 followers View post →

Shams Salah Mahdi

@ShamsPath · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 3, 2024 · 41 shares · 1,425 followers View post →

Chidambara .ML.

@chidambara09 · X

RT @InnovOncology: Comprehensive review of #CRISPR-based gene editing: mechanisms, challenges, and applications in cancer therapy. #Oncolo…

Apr 3, 2024 · 4 shares · 11,722 followers View post →

yuli.

@immuneoz · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 3, 2024 · 41 shares · 234 followers View post →

Top Biomedical Science

@imedverse · X

RT @InnovOncology: Comprehensive review of #CRISPR-based gene editing: mechanisms, challenges, and applications in cancer therapy. #Oncolo…

Apr 3, 2024 · 4 shares · 90,464 followers View post →

The Innovation Oncology

@InnovOncology · X

Apr 3, 2024 · 9 likes · 4 shares · 2,852 followers View post →

Hao Yin

@HaoYin20 · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 3, 2024 · 41 shares · 12,204 followers View post →

Sungmin Baek

@sbaek1981 · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 3, 2024 · 41 shares · 133 followers View post →

Moisés Sandoval C., PhD.

@m_sandoval11 · X

Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and applications in cancer therapy https://t.co/6f6dsHWJQl

Apr 3, 2024 · 1,865 followers View post →

Science

@Long_life_sci · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 3, 2024 · 41 shares · 33 followers View post →

Nagadusbdis

@Cryptikthinker · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 3, 2024 · 41 shares · 358 followers View post →

Dr. Vishal Agrawal

@best_vishu · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 3, 2024 · 41 shares · 382 followers View post →

Anam Kidwai

@kidwaiscience · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 3, 2024 · 41 shares · 433 followers View post →

Tina Han

@tingfordha · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 3, 2024 · 41 shares · 1,168 followers View post →

Raghav Ramabadran

@BMSplice · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 3, 2024 · 41 shares · 194 followers View post →

Mahmoud Qutb

@MahmoudTony19 · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

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yulicious1506

@yulicious1506 · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

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Hao Yin

@haoyin.bsky.social · Bluesky

Apr 3, 2024 · 4 likes · 5 shares View post →

Debasish Roy, Ph.D

@pryarthak86 · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 3, 2024 · 41 shares · 170 followers View post →

Chris Ilia

@IliaChris · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

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Amaya Lopez-Pascual

@amayalpzp · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 3, 2024 · 41 shares · 274 followers View post →

Sahba Ferdowsi DO (conciergedoc)

@DrFerdowsi · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 3, 2024 · 41 shares · 9,651 followers View post →

nike

@wot_mikey · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 3, 2024 · 41 shares · 462 followers View post →

shochan92

@shochan9210 · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 3, 2024 · 41 shares · 89 followers View post →

shawn

@cgtsana · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 3, 2024 · 41 shares · 27 followers View post →

choiLab

@jungminchoilab · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 3, 2024 · 41 shares · 331 followers View post →

JYChoi_Neuroloscientist

@ChoiJunYoung20 · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 3, 2024 · 41 shares · 21 followers View post →

Phenomics

@Phenomics_J · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 3, 2024 · 41 shares · 1,523 followers View post →

Manoj Mayogi Mishra

@mayogisense · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 3, 2024 · 41 shares · 573 followers View post →

Nightmærish Sutures

@SyncreticMetria · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 3, 2024 · 41 shares · 113 followers View post →

Rio Sugimura

@rio_sugimura · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 3, 2024 · 41 shares · 3,165 followers View post →

HerniaHerney

@HerniaHerney · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 3, 2024 · 41 shares · 27 followers View post →

Weitao Lin

@weitao_lin · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 3, 2024 · 41 shares · 399 followers View post →

Z. G.

@SuperstringTx · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 3, 2024 · 41 shares · 210 followers View post →

Dr Jean Pierre Laroche #vacciné 6.0

@Echoraljpangio · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 3, 2024 · 41 shares · 2,714 followers View post →

Charles Dussiau

@DussiauC · X

RT @HaoYin20: My continued biomedical education Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and application…

Apr 3, 2024 · 41 shares · 214 followers View post →

Hao Yin

@HaoYin20 · X

Apr 3, 2024 · 131 likes · 41 shares · 12,204 followers View post →

Jette is Mataray

@white_bite · X

@mrsunlawyer That technology is amazing by the way. There are studies on how it can be applied for cancer treatment that are ongoing. For those interested: https://t.co/Awd35V2kaC

Mar 20, 2024 · 4,716 followers View post →

RISTEX（RInCA）_公正なゲノム情報利活用の法整備PJ

@Genome_ELSI_JP · X

ゲノム編集技術CRISPRを使ったがん治療・メカニズム・課題点について包括的にまとめたレビュー論文 "Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and applications in cancer therapy" https://t.co/eufzwjuCkN

Jan 31, 2024 · 1 like · 31 followers View post →

CRISP_SCIENCE

@ScienceCrisp · X

Jan 14, 2024 · 3 likes · 1,915 followers View post →

Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and applications in cancer therapy.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

CRISPR Therapy for CPS1 Deficiency: A Breakthrough Case Study

“CRISPR & Gene Editing: Rewriting the Code of Life”

Advancing CAR T-Cell Therapy with CRISPR Gene Editing Techniques

CRISPR Gene Editing in Cancer Therapy: Mechanisms and Challenges