March 2024 PMID 38244989

Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial and meta-analysis of 3 cognitive studies within COSMOS.

Chirag M Vyas, JoAnn E Manson, Howard D Sesso, Nancy R Cook, Pamela M Rist, Alison Weinberg, M Vinayaga Moorthy, Laura D Baker, Mark A Espeland, Lok-Kin Yeung, Adam M Brickman, Olivia I Okereke

Mentions

366
Peak: 43 in Jan 2024
across 7 sources since Jan 2024

Extended reach

1,657,186
potential audience

Total likes

5,698

Video views

214,062

Mentions per month

Jan 2024 – Nov 2025

Where it's discussed

  • News260 articles
  • X / Twitter65 posts
  • Blogs17 articles
  • Facebook9 posts
  • YouTube8 videos
  • Reddit6 posts
  • Bluesky1 posts

AI synopsis

What people are saying

The overall tone indicates moderate support and interest, exemplified by comments praising the meta-analysis findings and noting that multivitamins can improve memory and slow mental decline. Words like 'significantly improved' and references to specific trials convey a serious engagement with the research, although some responses are cautiously optimistic rather than completely enthusiastic.

AgreementModerate agreement

Most discussions support the positive findings of the study, emphasizing the benefits of multivitamin-mineral supplements for cognition.

InterestModerate interest

The discussions show moderate curiosity, with some users highlighting study details or questioning small effects.

EngagementModerate engagement

Participants refer to specific studies, meta-analyses, and methodological aspects, indicating a willingness to explore the research.

ImpactModerate impact

The emphasis on the potential for cognitive benefits and references to recognized scientific efforts suggest a recognition of meaningful impact.

Top posts

Most liked on X and Bluesky
chydorina
@chydorina · X

Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial and meta-analysis of 3 cognitive studies within COSMOS https://t.co/yNyQNV36Ql https://t.co/YRQeBsEEgE

Jan 19, 2024 · 54 likes · 11 shares · 16,445 followers View post →
Shaun Ward
@MyNutritionSci · X

I'm one of few nutritionists that support multivitamin-mineral (MVM) supplementation in gen pop. In this meta-analysis of COSMOS cognitive substudies (a large RCT lasting 1–3 years; outcome-dependent), MVM benefitted global cognition and episodic memory. https://t.co/7PXz5vyaR7

Jun 12, 2024 · 29 likes · 2 shares · 2,388 followers View post →
Agingdoc
@agingdoc1 · X

Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of (COSMOS)…

Jan 27, 2024 · 25 likes · 8 shares · 41,290 followers View post →
Wolfgang Marx
@Marx_Wolf · X

Jan 28, 2024 · 16 likes · 3 shares · 1,279 followers View post →
Sergey Minaev
@sminaev2015 · X

Effect of multivitamin-mineral supplementation versus placebo on cognitive function https://t.co/NlBe5igvly

Jan 18, 2024 · 10 likes · 2 shares · 31,439 followers View post →
Pon|食と健康
@PonNutr · X

米国で行われた大規模RCT、COSMOS研究のレビュー(メタアナリシス)論文 ✅2年間にわたる長期摂取の結果、カカオポリフェノールは認知症を予防しないが、マルチビタミン&ミネラルは予防した https://t.co/BLeIw8PgUL

Jan 28, 2024 · 8 likes · 2,612 followers View post →

All mentions

Bilgehan
@bilgepektemek_ · X

Plasebo. Multivitamin/mineral takviyeleri epizodik bellek harici işe yaramıyor. Düzgün besleniyorsanız almanız gereken tavsiyeler yalnızca B12 ve magnezyum. Nüfusun yaklaşık %80 kadarı magnezyum eksikliğinden muzdarip. B12 ise diyetle almak artık zor. https://t.co/Q9ifvYK4G7 https://t.co/3b9Lcb9jJB

Oct 28, 2025 · 34 followers View post →
Audie
@RivianTrinity · X

@Gigachad11111 @Hilbe My notis is broken and I missed your reply. Here, let me help you out a bit... Try not to parrot things you hear and actually do your own digging. Oh and take your multivitamin

Oct 6, 2025 · 1 like · 123 followers View post →
Mr. D
@MrD1one · X

RT @foundmyfitness: @MsikoravMD Here's the study (a meta-analysis) I reference in the video. https://t.co/g79vUppBEv

Aug 13, 2025 · 1 share · 391 followers View post →
Dr. Rhonda Patrick
@foundmyfitness · X

@MsikoravMD Here's the study (a meta-analysis) I reference in the video. https://t.co/g79vUppBEv

Aug 12, 2025 · 3 likes · 1 share · 610,792 followers View post →
Damian
@namimzz · X

@cremieuxrecueil @whine_country What do you think about this small effect on global cognition? https://t.co/8Nlw4uP6lb

Apr 24, 2025 · 2 likes · 90 followers View post →
BIOHQ
@biohq.bsky.social · Bluesky

Apr 17, 2025 · 1 like View post →
CalerieLife
@CalerieLife · X

A meta-analysis showed that research over 2 yrs taking a multivitamin-mineral (MVM) provides health benefits. Both global cognition & episodic memory improved. This supports the benefits of taking an MVM to help prevent cognitive decline in older adults. https://t.co/VJgmsCenyF

Jan 16, 2025 · 65 followers View post →
チーム イベルメクチン
@ivermectin_team · X

マルチビタミンの毎日の補給は、高齢者の認知機能、特にエピソード記憶の改善に有益という論文です Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of the COcoa Supplement and Multivitamin Outcomes Study (COSMOS)

Dec 25, 2024 · 5 likes View post →
CalerieLife
@CalerieLife · X

Multiple Vitamin-Mineral formulas A meta-analysis cognitive sub-study was performed using neuropsychological assessments. It showed taking a multiple vitamin-mineral significantly improved cognition & memory & is good for mental decline during aging. https://t.co/VJgmsCdPJ7

Jul 22, 2024 · 65 followers View post →
Joel "Heart Prevention" Kahn MD, FACC
@drjkahn · X

Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcoh… https://t.co/d85JNGF90u

Jul 18, 2024 · 32,288 followers View post →
angela davies
@angelad86569513 · X

https://t.co/zaHlwmiEJr

Jul 10, 2024 · 129 followers View post →
Alessandro Falcone
@alessandro_fac_ · X

@GidMK What about mental benefits in the COSMOS trial? https://t.co/w2HVo7BNA4

Jun 28, 2024 · 9 followers View post →
reD
@ReDDay20 · X

@lkvme @avargano35 @ChroniclesofWa1 Исследование COSMOS: Это исследование  изучало  влияние  ЭМП  от  радиочастотных  излучателей  на  здоровье  детей  и  подростков.  Оно  показало,  что  у  детей,  которые  жили  вблизи  вышек  сотовой  связи,  на  50%  риск  развития  нейробластомы.  https://t.co/OB0GocDnVQ

Jun 26, 2024 · 259 followers View post →
Leorex
@LeorexMufasa · X

RT @WardWriting: I'm one of few nutritionists that support multivitamin-mineral (MVM) supplementation in gen pop. In this meta-analysis of…

Jun 13, 2024 · 2 shares · 9 followers View post →
Tiger_MD
@PlantBasedLift1 · X

RT @WardWriting: I'm one of few nutritionists that support multivitamin-mineral (MVM) supplementation in gen pop. In this meta-analysis of…

Jun 13, 2024 · 2 shares · 380 followers View post →
Shaun Ward
@MyNutritionSci · X

I'm one of few nutritionists that support multivitamin-mineral (MVM) supplementation in gen pop. In this meta-analysis of COSMOS cognitive substudies (a large RCT lasting 1–3 years; outcome-dependent), MVM benefitted global cognition and episodic memory. https://t.co/7PXz5vyaR7

Jun 12, 2024 · 29 likes · 2 shares · 2,388 followers View post →
Kelly A. Hogan Ph.D.
@Loose_Lab_Rat · X

Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of the COSMOS randomized clinical trial and meta-analysis of 3 cognitive studies within COSMOS https://t.co/DNyPO38buC

Mar 12, 2024 · 2,242 followers View post →
Improved Health Through Vitamins
@HealthyIowans · X

Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial and meta-analysis of 3 cognitive studies https://t.co/THly06HF3w

Mar 12, 2024 · 1 like · 17 followers View post →
Healthy for Life
@Healthy4Life365 · X

Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial and meta-analysis of 3 cognitive studies https://t.co/grZaJXBqNC

Mar 11, 2024 · 22 followers View post →
Gym In Motion
@GymInMotion · X

Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of the COcoa Supplement & Multivitamin Outcomes Study (COSMOS) randomised clinical trial & meta-analysis of 3 cognitive studies. https://t.co/DV2HUtJumS

Feb 21, 2024 · 194 followers View post →
ForensicPsyMD
@ForensicPsyMD · X

Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial and meta-analysis of 3 cognitive studies https://t.co/O8fkAdyA1T

Feb 14, 2024 · 362 followers View post →
Kelly A. Hogan Ph.D.
@Loose_Lab_Rat · X

Effect of multivitamin-mineral supplementation versus placebo on cognitive function https://t.co/DNyPO38buC

Feb 13, 2024 · 2,242 followers View post →
Richard Butin
@Dr_Butin · X

Effect of multivitamin-mineral supplementation versus placebo on cognitive function: Daily MVI helps according 3 cognitive studies within COSMOS - The American Journal of Clinical Nutrition https://t.co/Mc4R80InkD

Feb 7, 2024 · 2 likes · 853 followers View post →
Thinking Autism
@TweetingAutism · X

RT @Marx_Wolf:

Feb 5, 2024 · 3 shares · 14,332 followers View post →
Mind Your Science!
@MindYourSci · X

RT @agingdoc1: Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of (C…

Jan 30, 2024 · 8 shares · 133 followers View post →
Scigote
@scigote · X

RT @Marx_Wolf:

Jan 29, 2024 · 3 shares · 219 followers View post →
Adrián Carballo-Casla
@acarballocasla · X

RT @LSchwingshackl: Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohor…

Jan 29, 2024 · 1 share · 206 followers View post →
Lukas Schwingshackl
@LSchwingshackl · X

Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of the COcoa Supplement and Multivitamin Outcomes Study RCT and meta-analysis of 3 cognitive studies within COSMOS https://t.co/VE3BJ4BvGV

Jan 29, 2024 · 6 likes · 1 share · 1,507 followers View post →
Dr. Uma Naidoo
@DrUmaNaidoo · X

@massgen Vyas CM et al. Effect of multivitamin-mineral supplementation versus placebo on cognitive function: Results from the clinic sub-cohort of the COSMOS randomized clinical trial and meta-analysis of three cognitive studies within COSMOS. Am J Clin Nutr. 2023 PMID: 38244989.

Jan 28, 2024 · 2 likes · 12,928 followers View post →
Paul Whiteley
@PaulWhiteleyPhD · X

RT @Marx_Wolf:

Jan 28, 2024 · 3 shares · 4,930 followers View post →
Wolfgang Marx
@Marx_Wolf · X

Jan 28, 2024 · 16 likes · 3 shares · 1,279 followers View post →
Ultra Vitality Health M.D.
@UltraVitalityMD · X

RT @agingdoc1: Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of (C…

Jan 28, 2024 · 8 shares · 860 followers View post →
Agingdoc
@agingdoc1 · X

RT @agingdoc1: Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of (C…

Jan 28, 2024 · 8 shares · 41,290 followers View post →
Pon|食と健康
@PonNutr · X

米国で行われた大規模RCT、COSMOS研究のレビュー(メタアナリシス)論文 ✅2年間にわたる長期摂取の結果、カカオポリフェノールは認知症を予防しないが、マルチビタミン&ミネラルは予防した https://t.co/BLeIw8PgUL

Jan 28, 2024 · 8 likes · 2,612 followers View post →
Roland
@Robelix61 · X

RT @agingdoc1: Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of (C…

Jan 28, 2024 · 8 shares · 923 followers View post →
briellxxy
@briellxxy · X

RT @agingdoc1: Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of (C…

Jan 28, 2024 · 8 shares · 7 followers View post →
The Longevist
@Dr_coachbear · X

RT @agingdoc1: Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of (C…

Jan 27, 2024 · 8 shares · 515,515 followers View post →
Dr. Shashank Joshi
@AskDrShashank · X

RT @agingdoc1: Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of (C…

Jan 27, 2024 · 8 shares · 32,534 followers View post →
BrendenMHorn
@BrendenMHorn · X

RT @agingdoc1: Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of (C…

Jan 27, 2024 · 8 shares · 271 followers View post →
Agingdoc
@agingdoc1 · X

Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of (COSMOS)…

Jan 27, 2024 · 25 likes · 8 shares · 41,290 followers View post →
PubMed Trending
@PubTrend · X

Trending on PubMed: Effect of multivitamin-mineral supplementation versus placebo on cognitive function: Results from the clinic sub-cohort of the COSMOS randomized clinical trial and meta-analysis of three cognitive studies within COSMOS. https://t.co/qqJG2wHb9U

Jan 26, 2024 · 5,154 followers View post →
Abdelhamid Hamdy
@abdelhamed012 · X

Effect of multivitamin-mineral supplementation versus placebo on cognitive function: Results from the clinic sub-cohort of the COSMOS randomized clinical trial and meta-analysis of three cognitive studies within COSMOS - The American Journal of Clinical https://t.co/ZuPGhAZ9aD

Jan 24, 2024 · 3,302 followers View post →
luis alberto malaga
@malaga1711 · X

RT @manut82004: Effect of multivitamin-mineral supplementation versus placebo on cognitive function: Results from the clinic sub-cohort of…

Jan 23, 2024 · 1 share · 1,602 followers View post →
Marco Melgarejo
@manut82004 · X

Effect of multivitamin-mineral supplementation versus placebo on cognitive function: Results from the clinic sub-cohort of the COSMOS randomized clinical trial and meta-analysis of three cognitive studies within COSMOS - The AJCN https://t.co/jPDpjF4FSw

Jan 23, 2024 · 3 likes · 1 share · 889 followers View post →
Cheems es mi pastor
@alterangel · X

Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) - ScienceDirect https://t.co/KYsKUmg4FU

Jan 22, 2024 · 1 like · 541 followers View post →
Sreeram Penna
@SreeramPenna · X

@newscientist Interesting research: https://t.co/SJJX5OCxW2 Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial and meta-analysis of

Jan 22, 2024 · 77 followers View post →
HEMA SARANYA ILAMATHI
@HS_Ilamathi · X

Is it possible to prevent HIV? Check out the Sci-Nib channel to find out the answer and learn about other scientific discoveries. An interesting question awaits you

Jan 21, 2024 · 1 like · 33 followers View post →
Robert Olney
@boretrol · X

Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial ... https://t.co/DLDy2OwRPC

Jan 20, 2024 · 1,658 followers View post →
flygurl
@fly_gurl16 · X

RT @chydorina: Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of th…

Jan 19, 2024 · 11 shares · 165 followers View post →
Cutie Circle
@CutieCircle · X

RT @chydorina: Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of th…

Jan 19, 2024 · 11 shares · 958 followers View post →
Sinéad Peace Piece
@BerzinsPetsits · X

RT @chydorina: Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of th…

Jan 19, 2024 · 11 shares · 4,301 followers View post →
TheSunshineVitamin
@TheSunshineVit1 · X

RT @chydorina: Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of th…

Jan 19, 2024 · 11 shares · 956 followers View post →
Eileen
@dreamsharp · X

RT @chydorina: Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of th…

Jan 19, 2024 · 11 shares · 283 followers View post →
MindFeast622
@MindFeast622 · X

RT @chydorina: Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of th…

Jan 19, 2024 · 11 shares · 6,843 followers View post →
Kristen
@kcdubz · X

RT @chydorina: Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of th…

Jan 19, 2024 · 11 shares · 4,455 followers View post →
I told Captcha I'm human
@NimatGray · X

RT @chydorina: Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of th…

Jan 19, 2024 · 11 shares · 351 followers View post →
Linda Schwartz
@LenkaB99 · X

RT @chydorina: Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of th…

Jan 19, 2024 · 11 shares · 381 followers View post →
P123
@P1231032850 · X

RT @chydorina: Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of th…

Jan 19, 2024 · 11 shares · 3,410 followers View post →
chydorina
@chydorina · X

Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial and meta-analysis of 3 cognitive studies within COSMOS https://t.co/yNyQNV36Ql https://t.co/YRQeBsEEgE

Jan 19, 2024 · 54 likes · 11 shares · 16,445 followers View post →
NFLCSFacts
@NFLObjectors · X

Effect of multivitamin-mineral supplementation versus placebo on cognitive function: COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial and meta-analysis of 3 cognitive studies within COSMOS - https://t.co/PrGsQYXjPR Did it check deficiencies?

Jan 19, 2024 · 1,917 followers View post →
Sergey Minaev
@sminaev2015 · X

RT @sminaev2015: Effect of multivitamin-mineral supplementation versus placebo on cognitive function https://t.co/NlBe5igvly

Jan 19, 2024 · 2 shares · 31,439 followers View post →
Zin Joanna
@Wan53248124Zin · X

RT @sminaev2015: Effect of multivitamin-mineral supplementation versus placebo on cognitive function https://t.co/NlBe5igvly

Jan 19, 2024 · 2 shares · 139 followers View post →
Sergey Minaev
@sminaev2015 · X

Effect of multivitamin-mineral supplementation versus placebo on cognitive function https://t.co/NlBe5igvly

Jan 18, 2024 · 10 likes · 2 shares · 31,439 followers View post →
中武 壮以知
@soichinakatake · X

「毎日のマルチビタミン・ミネラルサプリメントが全体的な認知とエピソード記憶の両方に大きな利益をもたらすことが示されています」 Effect of multivitamin-mineral supplementation versus placebo on cognitive function: https://t.co/YaisshEOkG

Jan 18, 2024 · 137 followers View post →
leslie sheppard
@leslieasheppard · X

Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial and meta-analysis of 3 cognitive studies… https://t.co/ObGwHiZLen

Jan 18, 2024 · 1,785 followers View post →
Evan Beloff
@evanbeloff · X

Study: Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of the COcoa Supplement & Multivitamin Outcomes Study (COSMOS) randomized clinical trial and meta-analysis of 3 cognitive studies https://t.co/gDBORdf0dP

Jan 18, 2024 · 231 followers View post →