Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction https://t.co/B30oeIqI9U
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction.
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Sep 2023 – Jul 2025Where it's discussed
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What people are saying
Posts frequently praise the study as 'mind-blowing' and describe the therapy as a promising and potentially revolutionary intervention in aging. The tone is optimistic and excited, with expressions like 'Welcome to the future!' and references to long-lasting, prophylactic effects, illustrating high interest and perceived significance in the scientific and broader community.
Most discussions express strong support and excitement for the study's findings, highlighting its potential importance in aging research.
The discussions show a high level of curiosity and enthusiasm, with posters emphasizing the groundbreaking nature of the research.
Many posts delve into details like long-term effects, method significance, and potential applications, indicating deep engagement.
Widespread acknowledgment of the research as a possible 'game changer' or advancing anti-aging therapy demonstrates perceived high impact.
Abstract in brief
- The study discusses developing CAR T cells that target and eliminate senescent cells expressing uPAR, which accumulate with age and contribute to tissue decline.
- These CAR T cells effectively improve physical fitness and metabolic health, such as better exercise capacity and glucose tolerance, in aging and high-fat diet mice.
- A single dose of these CAR T cells provides long-lasting benefits, making this a promising long-term therapy for age-related metabolic problems.]
Top posts
Most liked on X and BlueskyProphylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction
Prof Vegas team at Cold Spring Harbor Laboratory found that T cells can be reprogrammed to combat aging, with potential lifelong effects. These CAR T cells are capable of targeting senescent cells, which contribute to aging-related problems and diseases. https://t.co/LoXB18gDGu
Congratulations @corina_amor_MD! Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction https://t.co/p8Ku6Flj7B
Yo @bryan_johnson great news! A One-and-Done Injection to Slow Aging? New Study in Mice Opens the Possibility Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction "Yet a new study led by Dr. Corina Amor Vegas at Cold Spring https://t.co/UWPgnVABT2 https://t.co/OQNAZaIjBx
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction | Nature Aging https://t.co/r1VrMd5fv4
All mentions
Senolytic CAR T Cells Offer Long-Term Age-Related Metabolic Benefits
Scientists unveil groundbreaking therapy using CAR T cells targeting uPAR to eliminate senescent cells, improving physical and metabolic health, with long-lasting effects in aging models.
Senolytic CAR T Cells for Treating Age-Related Metabolic Dysfunction
This video discusses developing CAR T cells that target and eliminate senescent cells expressing uPAR. These cells improve physical fitness and metabolic health in aging mice, offering a promising long-term therapy for…
Senolytic CAR T Cells for Anti-Aging and Metabolic Health
Explore how engineered CAR T cells targeting senescent cells expressing uPAR can improve physical and metabolic health in aging.
Mind-blowing!
Mind-blowing! CAR-T cells engineered to destroy senescent "zombie" cells that drive aging. One injection improved glucose control 25%, exercise capacity 40%, lasting 15+ months!
Mind-blowing!
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction https://t.co/wqIRwwL0oT
المرجع: https://t.co/PH5kIeokoo #السكري #الشيخوخة #السمنة https://t.co/m95Ay08bFu
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction https://t.co/oujHrVjVP7
RT @XX62: 『Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction』 Nature Aging 24 Janu…
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction | Nature Aging https://t.co/uqwjUVWeqI
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction | Nature Aging https://t.co/fhVwrnCWtJ
『Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction』 Nature Aging 24 January 2024 CAR-Tパイオニアの一人Michel Sadelain研究室 NEJM,NatureにCAR-T自己免疫疾患治療成績の論文が掲載された CAR-T本領発揮のアンチエイジング治療 https://t.co/3sI8N0kCJY
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction | Nature Aging https://t.co/fhVwrnCWtJ
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction. https://t.co/b4GpkF4LwS
Healthspan game changer?? "Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction." https://t.co/9QCi7OZ8oz
@bryan_johnson Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction https://t.co/409CHET0MZ
Yo @bryan_johnson great news! A One-and-Done Injection to Slow Aging? New Study in Mice Opens the Possibility Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction "Yet a new study led by Dr. Corina Amor Vegas at Cold Spring https://t.co/UWPgnVABT2 https://t.co/OQNAZaIjBx
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction. https://t.co/b4GpkF5jmq
Welcome to the Future! We’re going to end up with Immortality before Reparations
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction https://t.co/4f7GEWoZuC
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction [aka senolytic therapy based on CAR T cells targeting the senescence-associated protein urokinase plasminogen activator receptor (uPAR)] https://t.co/PkjMDyQyeL
RT @MinneBio: Prof Vegas team at Cold Spring Harbor Laboratory found that T cells can be reprogrammed to combat aging, with potential lifel…
RT @MinneBio: Prof Vegas team at Cold Spring Harbor Laboratory found that T cells can be reprogrammed to combat aging, with potential lifel…
RT @MinneBio: Prof Vegas team at Cold Spring Harbor Laboratory found that T cells can be reprogrammed to combat aging, with potential lifel…
Prof Vegas team at Cold Spring Harbor Laboratory found that T cells can be reprogrammed to combat aging, with potential lifelong effects. These CAR T cells are capable of targeting senescent cells, which contribute to aging-related problems and diseases. https://t.co/LoXB18gDGu
RT @AgingBiology: Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction https://t.co/B3…
...apparently they can also kill senescent cells that are one of the big contributors to ageing! Such an exciting technology. pubmed.ncbi.nlm.nih.gov/38267706/
RT @AgingBiology: Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction https://t.co/B3…
@davidasinclair @corina_amor_MD And I also thank the authors for showing the weight data (even though weight data for the animals of Fig. 6 is missing). This paper will be an instant classic & will be cited for decades to come as showing the benefits of senescent cell elimination. https://t.co/FU4nkdYYs2
RT @AgingBiology: Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction https://t.co/B3…
RT @AgingBiology: Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction https://t.co/B3…
https://t.co/zDbfn69wik CAR-T Therapy: Lifelong Clearance of Aging Cells Slows Aging Process. On Jan 24, Corina Amor and her team at Cold Spring Harbor Laboratory published a study titled "Prophylactic and long-lasting efficacy of senolytic CAR T cells against.... #antiaging
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RT @Zapata_Lab_IIBm: Impressive! T cells rule! https://t.co/qeUB4ZzJ2P
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction | Nature Aging https://t.co/akEgxSOPjz
RT @AgingBiology: Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction https://t.co/B3…
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction @NatureAging https://t.co/JPsvPwGJDl
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction https://t.co/B30oeIqI9U
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction
Impressive! T cells rule! https://t.co/qeUB4ZzJ2P
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction | Nature Aging https://t.co/klBRqCO2RK
RT @agingdoc1: Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction
Here is a link to an article, which is called "Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction" https://t.co/830OYaTkX2
RT @agingdoc1: Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction | Nature Aging https://t.co/JXW1VDi6aM
元論文→ Reference: Amor C, Fernández-Maestre I, Chowdhury S, et al. Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction. Nat Aging. 2024. doi: 10.1038/s43587-023-00560-5 https://t.co/ebYAbTtyRZ
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction: https://t.co/I8ye2VzBYD
@WmHaseltine I've looked forward to CAR-T fruit 4 10 yrs From @CSHL (where as child spent many hours"playing"(sorting seeds) 4 Barbara McClintock) https://t.co/xC0P5SO1IP "Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction"
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction | Nature Aging https://t.co/YZJqqwWYSH
した。また、高齢マウスに投与した場合は若返り効果もありました。さらに、これらすべての利点は、一切の副作用を伴いませんでした。Nature Aging誌https://t.co/mSB5JMbqFw
For long-term preventive effects ? "Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction." Nat Aging (2024). https://t.co/Uc2id8tyl3 @isaperarnau @brunovellas @RestoreInstitut @InfinityTLS @I2mcT
RT @bhemato: Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction | Nature Aging https…
RT @bhemato: Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction | Nature Aging https…
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction | Nature Aging https://t.co/r1VrMd5fv4
RT @agingdoc1: Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction https://t.co/zqdKFbl7lB
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction https://t.co/ylBvIooZng
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction | Nature Aging https://t.co/t78J3uHR1Y
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction
Amor, C., Fernández-Maestre, I., Chowdhury, S. et al. Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction. Nat Aging (2024). https://t.co/r6Vr1K7Uu4
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction https://t.co/opsz5pcfAT @researchsquare https://t.co/2N5nCOD2Nm
RT @MattYousefzadeh: Congratulations @corina_amor_MD! Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related…
Congratulations @corina_amor_MD! Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction https://t.co/p8Ku6Flj7B