J Lipid Res March 2024 PMID 38272355

Finasteride delays atherosclerosis progression in mice and is associated with a reduction in plasma cholesterol in men.

Patrick McQueen, Donald Molina, Ivan Pinos, Samuel Krug, Anna J Taylor, Michael R LaFrano, Maureen A Kane, Jaume Amengual

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Mentions

77
Peak: 9 in Mar 2024
across 4 sources since Feb 2024

Extended reach

130,716
potential audience

Total likes

2,036

Video views

71,900

Mentions per month

Feb 2024 – Oct 2024

Where it's discussed

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  • X / Twitter10 posts
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  • YouTube4 videos

AI synopsis

What people are saying

The overall tone reflects a moderate but genuine interest in the research, evidenced by phrases like 'delays atherosclerosis' and 'reduction in plasma cholesterol,' which highlight the potential health benefits. Comments engaging with the findings suggest curiosity and a recognition of the study’s importance, such as questions about how finasteride might be used clinically, emphasizing its perceived impact.

AgreementModerate agreement

Most discussions acknowledge the positive findings about finasteride's potential benefits for cardiovascular health, indicating general support.

InterestModerate interest

Participants show curiosity about the research, with some expressing surprise or enthusiasm about the implications.

EngagementModerate engagement

The discussions demonstrate moderate engagement, with references to the study's significance and questions about its applications.

ImpactModerate impact

The tone suggests that many consider this research to have important medical implications, potentially influencing future treatment approaches.

Abstract in brief

  • Finasteride, a medication used for prostate issues and hair loss, was found to delay the progression of atherosclerosis (plaque buildup in arteries) in mice and reduce plasma cholesterol levels in men.
  • In mice, finasteride decreased inflammation-related processes and changed liver function related to cholesterol and bile acid metabolism, which contributed to its protective effects against artery plaque development.
  • Human data analysis showed that men taking finasteride had lower levels of total cholesterol and LDL cholesterol, suggesting it might have potential benefits in preventing cardiovascular disease.]

Top posts

Most liked on X and Bluesky
Agingdoc
@agingdoc1 · X

Finasteride delays atherosclerosis progression in mice and is associated with a reduction in plasma cholesterol in men https://t.co/SDOHs9dh1g https://t.co/WQqJ2R8MaK

Mar 1, 2024 · 47 likes · 5 shares · 41,696 followers View post →
Dr. Michael Sagner, MD
@DrMichaelSagner · X

RT @agingdoc1: Finasteride delays atherosclerosis progression in mice and is associated with a reduction in plasma cholesterol in men http…

Mar 1, 2024 · 5 shares · 5,360 followers View post →
Pharmica
@pharmicauk · X

Source: https://t.co/HtIn6OwKU7

Jun 11, 2024 · 3,238 followers View post →
Pharmica
@pharmicauk · X

Source: https://t.co/HtIn6OwKU7

Jun 11, 2024 · 3,238 followers View post →
Roger Blackwell
@rogerablackwell · X

Finasteride delays atherosclerosis progression in mice and is associated with a reduction in plasma cholesterol in men https://t.co/MYq9UFGCJt

Mar 1, 2024 · 2,307 followers View post →
MCAS, PTSD and ME
@FatigueMe92484 · X

RT @agingdoc1: Finasteride delays atherosclerosis progression in mice and is associated with a reduction in plasma cholesterol in men http…

Mar 1, 2024 · 5 shares · 1,187 followers View post →

All mentions

Pharmica
@pharmicauk · X

Source: https://t.co/HtIn6OwKU7

Jun 11, 2024 · 3,238 followers View post →
Pharmica
@pharmicauk · X

Source: https://t.co/HtIn6OwKU7

Jun 11, 2024 · 3,238 followers View post →
サイエンスあれこれ
@sarekore · X

男性)とサンプルサイズが小さく、マウスでの効果は、ヒトに通常処方される1日1~5mgと比較して非常に高用量の1日約2.5mgでのみ観察されました。https://t.co/EbhBR4IgtD

Mar 3, 2024 · 920 followers View post →
Mind Your Science!
@MindYourSci · X

RT @agingdoc1: Finasteride delays atherosclerosis progression in mice and is associated with a reduction in plasma cholesterol in men http…

Mar 2, 2024 · 5 shares · 133 followers View post →
Murat Turkoglu
@MTurk255 · X

RT @agingdoc1: Finasteride delays atherosclerosis progression in mice and is associated with a reduction in plasma cholesterol in men http…

Mar 2, 2024 · 5 shares · 577 followers View post →
Sivaprakasam Chinnarasu, PhD
@sivabdubio · X

RT @agingdoc1: Finasteride delays atherosclerosis progression in mice and is associated with a reduction in plasma cholesterol in men http…

Mar 1, 2024 · 5 shares · 101 followers View post →
Dr. Michael Sagner, MD
@DrMichaelSagner · X

RT @agingdoc1: Finasteride delays atherosclerosis progression in mice and is associated with a reduction in plasma cholesterol in men http…

Mar 1, 2024 · 5 shares · 5,360 followers View post →
MCAS, PTSD and ME
@FatigueMe92484 · X

RT @agingdoc1: Finasteride delays atherosclerosis progression in mice and is associated with a reduction in plasma cholesterol in men http…

Mar 1, 2024 · 5 shares · 1,187 followers View post →
Agingdoc
@agingdoc1 · X

Finasteride delays atherosclerosis progression in mice and is associated with a reduction in plasma cholesterol in men https://t.co/SDOHs9dh1g https://t.co/WQqJ2R8MaK

Mar 1, 2024 · 47 likes · 5 shares · 41,696 followers View post →
Roger Blackwell
@rogerablackwell · X

Finasteride delays atherosclerosis progression in mice and is associated with a reduction in plasma cholesterol in men https://t.co/MYq9UFGCJt

Mar 1, 2024 · 2,307 followers View post →