J Am Coll Cardiol February 2024 PMID 38355240

Effect of a Salt Substitute on Incidence of Hypertension and Hypotension Among Normotensive Adults.

Xianghui Zhang, Yifang Yuan, Chenglong Li, Xiangxian Feng, Hongxia Wang, Qianku Qiao, Ruijuan Zhang, Aoming Jin, Jiayu Li, Huijuan Li, Yangfeng Wu

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Mentions

201

Peak: 103 in Feb 2024

across 7 sources since Feb 2024

Extended reach

853,256

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AI synopsis

What people are saying

The discussions reflect a generally positive stance, emphasizing the study's findings that salt substitutes could lower hypertension risk without increasing hypotension, with examples like 'potential for population-wide prevention' and 'lower risk of high blood pressure.' The tone and references to specific groups and statistical data indicate moderate engagement and perceived importance of the research.

AgreementModerate agreement

Most discussions support the positive findings of the study, emphasizing the potential benefits of salt substitutes for blood pressure management.

InterestModerate interest

The discussions show a moderate level of curiosity, with many posts highlighting the safety and health implications, indicating relevance to health interests.

EngagementModerate engagement

Participants reference study details, such as reducing hypertension risk and specific groups like older adults, demonstrating thoughtful engagement.

ImpactModerate impact

The emphasis on the preventive potential and widespread health relevance suggests these discussions view the publication as having a meaningful impact.

Abstract in brief

The study found that using a salt substitute (with 25% KCl) among older adults with normal blood pressure reduced the risk of developing hypertension without increasing hypotension episodes.
There was no significant change in blood pressure levels in the salt substitute group, whereas the usual salt group experienced an increase, leading to a net benefit in blood pressure readings.
Overall, replacing regular salt with salt substitutes could be an effective and safe strategy for preventing hypertension in older adults, warranting further research.]

Read the full abstract

All mentions

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The study investigated the effects of a salt substitute containing potassium chloride on stroke and cardiovascular outcomes among older adults with high blood pressure and a history of stroke in rural China. Results…

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Salt Substitution for Blood Pressure Prevention Based on Scientific Evidence

Replacing regular salt with potassium-enriched salt can lower the risk of hypertension and heart disease. This science-backed approach helps maintain healthy blood pressure levels without stress or extremes.

93inspire · Jun 4, 2025 2,856 views

Clara Dawn Ellington

@temple_bblythe · X

RT @EricTopol: A randomized trial of a salt substitute vs usual salt intake in people (mean age 71, Chinese population) with normal blood p…

Aug 8, 2025 · 163 shares · 504 followers View post →

AhmadHesam

@AhmadHe88222021 · X

Ernährung bei Bluthochdruck: "Das sagt Dir kein Arzt!" Diese Gewohnheiten können gefährlich werden! https://t.co/2YTdJMvueq

Dec 19, 2024 · 97 followers View post →

Henri Mourant

@henri_mourant · X

@DeadEyedVVitch @espidotme @cs_deathmatch Hmm well here's a trial looking at its effects on people with normal blood pressure. However they are elderly. https://t.co/EsUJDtSEcR

Sep 1, 2024 · 3 likes · 961 followers View post →

@investigando

@rocatanho · X

En adultos mayores con presión arterial normal, reemplazar la sal con un sustituto puede reducir la incidencia de hipertensión sin aumentar los episodios de hipotensión #saltsubstitute #BP https://t.co/IvXsksIptL

Jun 4, 2024 · 400 followers View post →

Hypertension Australia

@HypertensionAus · X

RT @spjuraschek: Nice study showing the safety of salt substituton for populationwide prevention if hypertension! Effect of a Salt Substit…

Mar 3, 2024 · 3 shares · 3,074 followers View post →

J. Brian Byrd Lab

@thebyrdlab · X

RT @spjuraschek: Nice study showing the safety of salt substituton for populationwide prevention if hypertension! Effect of a Salt Substit…

Mar 1, 2024 · 3 shares · 4,602 followers View post →

Edoardo Melilli

@EdoardoMelilli · X

RT @spjuraschek: Nice study showing the safety of salt substituton for populationwide prevention if hypertension! Effect of a Salt Substit…

Mar 1, 2024 · 3 shares · 3,263 followers View post →

Stephen Juraschek MD, PhD, FAHA, AHSCP-CHS

@spjuraschek · X

Mar 1, 2024 · 17 likes · 3 shares · 2,657 followers View post →

Alice_Bob_2020 (帆船有理子)

@AliceBob20201 · X

RT @Astella6174: 代替食塩 2年間の研究期間中、ナトリウムの少ない代替食塩群（カリウム、キノコ、レモン等が含まれてる）では通常の食塩群よりも高血圧になる可能性が40％低かった。一方低血圧の発症率はほぼ同じで、「血圧の低下」ではなく「血圧の上昇を防ぐ」効果があっ…

Feb 23, 2024 · 1 share · 310 followers View post →

おくさん/OKUSUN

@Astella6174 · X

代替食塩 2年間の研究期間中、ナトリウムの少ない代替食塩群（カリウム、キノコ、レモン等が含まれてる）では通常の食塩群よりも高血圧になる可能性が40％低かった。一方低血圧の発症率はほぼ同じで、「血圧の低下」ではなく「血圧の上昇を防ぐ」効果があった、と。 https://t.co/5fwj6YnMeA

Feb 23, 2024 · 5 likes · 1 share · 1,187 followers View post →

Johns Hopkins Memory & Aging

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RT @agingdoc1: Effect of a Salt Substitute on Incidence of Hypertension and Hypotension Among Normotensive Adults

Feb 23, 2024 · 5 shares · 2,898 followers View post →

Slawomir

@Slawomi18369321 · X

RT @agingdoc1: Effect of a Salt Substitute on Incidence of Hypertension and Hypotension Among Normotensive Adults

Feb 23, 2024 · 5 shares · 85 followers View post →

Mind Your Science!

@MindYourSci · X

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Kamil Pabis

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Carlos

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Agingdoc

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Effect of a Salt Substitute on Incidence of Hypertension and Hypotension Among Normotensive Adults

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Andres Felipe Florez

@Andresffmed · X

RT @EricTopol: A randomized trial of a salt substitute vs usual salt intake in people (mean age 71, Chinese population) with normal blood p…

Feb 22, 2024 · 163 shares · 159 followers View post →

SFC - Société Française de Cardiologie

@SFCardio · X

Effect of a Salt Substitute on Incidence of Hypertension and Hypotension Among Normotensive Adults

Feb 20, 2024 · 2 likes · 4,706 followers View post →

Intergalactic Mind Games

@__I_M_GAMES__ · X

RT @protoninfo: Salty News Use of salt substitutes may be associated with lower risk of high blood pressure, study finds https://t.co/pTh0…

Feb 18, 2024 · 1 share · 19 followers View post →

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Dr.MikeGalindo

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Nicolas Renna, MD PhD ISHF FESC

@nicolasrennamd · X

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Gonzalo Perez

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James Bullen

@jamesbullen · X

RT @EricTopol: A randomized trial of a salt substitute vs usual salt intake in people (mean age 71, Chinese population) with normal blood p…

Feb 15, 2024 · 163 shares · 1,486 followers View post →

leroyvanderberg

@physiquecheck · X

RT @john_damianosMD: Salt substitutes such as potassium chloride and other flavorings such as mushroom, seaweed and lemon are protective ag…

Feb 15, 2024 · 2 shares · 11 followers View post →

Juan Peiró #SEMERGEN24

@Juan_PeiroM · X

RT @ana_apiecar: Effect of a Salt Substitute on Incidence of Hypertension and Hypotension Among Normotensive Adults | Journal of the Americ…

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Josué Félix Córdova

@Noinvasivo · X

RT @ana_apiecar: Effect of a Salt Substitute on Incidence of Hypertension and Hypotension Among Normotensive Adults | Journal of the Americ…

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juan ramon

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RT @ana_apiecar: Effect of a Salt Substitute on Incidence of Hypertension and Hypotension Among Normotensive Adults | Journal of the Americ…

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Showboat7

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RT @EricTopol: A randomized trial of a salt substitute vs usual salt intake in people (mean age 71, Chinese population) with normal blood p…

Feb 14, 2024 · 163 shares · 1,500 followers View post →

SEMERGEN_CV

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RT @ana_apiecar: Effect of a Salt Substitute on Incidence of Hypertension and Hypotension Among Normotensive Adults | Journal of the Americ…

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Ana Piera #JuntosEsMasFacil

@ana_apiecar · X

Effect of a Salt Substitute on Incidence of Hypertension and Hypotension Among Normotensive Adults | Journal of the American College of Cardiology https://t.co/FpUEaiTSdH @gt_hta @vic_pallares @Mitotatu @ManuelGorostidi @SEHLELHA140_90 https://t.co/zQS2CBnlhK

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Malamo Countouris

@malamo512 · X

RT @EricTopol: A randomized trial of a salt substitute vs usual salt intake in people (mean age 71, Chinese population) with normal blood p…

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Pino Quintaliani

@Pqr9ap · X

RT @EricTopol: A randomized trial of a salt substitute vs usual salt intake in people (mean age 71, Chinese population) with normal blood p…

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Rx Readmore Livemore

@SopitaSirirata1 · X

RT @DrDerekConnolly: Effect of a Salt Substitute on Incidence of Hypertension and Hypotension Among Normotensive Adults In older adults wi…

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fernando reyes

@ferreyec · X

RT @EricTopol: A randomized trial of a salt substitute vs usual salt intake in people (mean age 71, Chinese population) with normal blood p…

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Ellie Jones

@_ELLIE_JONES_x · X

RT @DrDerekConnolly: Effect of a Salt Substitute on Incidence of Hypertension and Hypotension Among Normotensive Adults In older adults wi…

Feb 14, 2024 · 2 shares · 754 followers View post →

Prof Derek Connolly

@DrDerekConnolly · X

Effect of a Salt Substitute on Incidence of Hypertension and Hypotension Among Normotensive Adults In older adults with normal BP replacing usual salt with a salt substitute may reduce the incidence of hypertension without increasing hypotension https://t.co/ajeKi4LfDR https://t.co/JabMzMCUaK

Feb 14, 2024 · 9 likes · 2 shares · 3,931 followers View post →

@investigando

@rocatanho · X

En adultos mayores con presión arterial normal, reemplazar la sal usual con un sustituto puede reducir la incidencia de hipertensión sin aumentar los episodios hipotensivos #saltsubstitute #hypertension https://t.co/IvXsksHREd

Feb 14, 2024 · 1 like · 400 followers View post →

Ernest Spitzer

@spitzertweets · X

RT @EricTopol: A randomized trial of a salt substitute vs usual salt intake in people (mean age 71, Chinese population) with normal blood p…

Feb 14, 2024 · 163 shares · 117 followers View post →

Angela Barnett

@Angela_Biochem · X

RT @EricTopol: A randomized trial of a salt substitute vs usual salt intake in people (mean age 71, Chinese population) with normal blood p…

Feb 14, 2024 · 163 shares · 560 followers View post →

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@NikaSamadzadeh · X

RT @EricTopol: A randomized trial of a salt substitute vs usual salt intake in people (mean age 71, Chinese population) with normal blood p…

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Kalina Ptaszynska

@kalinaptaszynsk · X

RT @EricTopol: A randomized trial of a salt substitute vs usual salt intake in people (mean age 71, Chinese population) with normal blood p…

Feb 14, 2024 · 163 shares · 90 followers View post →

Galvin Dhaliwal

@GSPINDOC · X

RT @john_damianosMD: Salt substitutes such as potassium chloride and other flavorings such as mushroom, seaweed and lemon are protective ag…

Feb 13, 2024 · 2 shares · 96 followers View post →

Umut. Dişel

@UmutDisel · X

RT @EricTopol: A randomized trial of a salt substitute vs usual salt intake in people (mean age 71, Chinese population) with normal blood p…

Feb 13, 2024 · 163 shares · 1,285 followers View post →

城　月

@joetsuki · X

RT @EricTopol: A randomized trial of a salt substitute vs usual salt intake in people (mean age 71, Chinese population) with normal blood p…

Feb 13, 2024 · 163 shares · 225 followers View post →

Roselie Bright, ScD, MS

@RoselieBright · X

RT @EricTopol: A randomized trial of a salt substitute vs usual salt intake in people (mean age 71, Chinese population) with normal blood p…

Feb 13, 2024 · 163 shares · 246 followers View post →

Maggie Buckley

@MaggieBuckley1 · X

RT @EricTopol: A randomized trial of a salt substitute vs usual salt intake in people (mean age 71, Chinese population) with normal blood p…

Feb 13, 2024 · 163 shares · 620 followers View post →

Patrick Pasqualicchio, DO

@pjpasqualicchio · X

RT @EricTopol: A randomized trial of a salt substitute vs usual salt intake in people (mean age 71, Chinese population) with normal blood p…

Feb 13, 2024 · 163 shares · 69 followers View post →

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RT @EricTopol: A randomized trial of a salt substitute vs usual salt intake in people (mean age 71, Chinese population) with normal blood p…

Feb 13, 2024 · 163 shares · 346 followers View post →

Carlos Duran, MD, MSc

@carlosed25779 · X

RT @EricTopol: A randomized trial of a salt substitute vs usual salt intake in people (mean age 71, Chinese population) with normal blood p…

Feb 13, 2024 · 163 shares · 357 followers View post →

José Mª Gª Quintana

@jose_g_quintana · X

RT @jsobrinom: Effect of a Salt Substitute on Incidence of Hypertension and Hypotension. https://t.co/n7uhqAjjCF @SEHLELHA140_90 @secardiol…

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Slippery Rider

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RT @EricTopol: A randomized trial of a salt substitute vs usual salt intake in people (mean age 71, Chinese population) with normal blood p…

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Ahmed Bennis MD

@drbennisahmed · X

Effect of a Salt Substitute on Incidence of Hypertension and Hypotension Among Normotensive Adults In Chinese older adults with normal blood pressure, replacing usual salt with a salt substitute may reduce the incidence of hypertension https://t.co/0IoWJGB7na https://t.co/QOfi3fGLPa

Feb 13, 2024 · 3 likes · 2,628 followers View post →

Juan H del Portillo

@delPortilloJH · X

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Feb 13, 2024 · 163 shares · 383 followers View post →

ping

@SerenePing808 · X

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JACC Journals

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RT @EricTopol: A randomized trial of a salt substitute vs usual salt intake in people (mean age 71, Chinese population) with normal blood p…

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Alberto Massarella

@massarellaalbMD · X

Effect of a Salt Substitute on Incidence of Hypertension and Hypotension Among Normotensive Adults | Journal of the American College of Cardiology https://t.co/S8TsgRMeis https://t.co/8asp7Br46N

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Cardio-Primària

@catcardiocamfic · X

RT @jsobrinom: Effect of a Salt Substitute on Incidence of Hypertension and Hypotension. https://t.co/n7uhqAjjCF @SEHLELHA140_90 @secardiol…

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Pepe ☮

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RT @EricTopol: A randomized trial of a salt substitute vs usual salt intake in people (mean age 71, Chinese population) with normal blood p…

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AntiMachineGunDeathInMassMurderistan = 2025ProLife

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ALKINDY Abdulrhman

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RT @gbiondizoccai: In older adults with normal blood pressure, replacing usual salt with a salt substitute may reduce the incidence of hype…

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Jan Hartmann, MD

@JanHartmannMD · X

Effect of a Salt Substitute on Incidence of Hypertension and Hypotension Among Normotensive Adults | Journal of the American College of Cardiology https://t.co/jv7pH4e3ct @Karl_Lauterbach

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Les Yonemoto, MD MBA

@protoninfo · X

Salty News Use of salt substitutes may be associated with lower risk of high blood pressure, study finds https://t.co/pTh0hX0HZU

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SEH-LELHA

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@MColebrook · X

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@JF_Renucci · X

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K810Mt

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RT @VipsMDMEd: “replacing usual salt with a salt substitute may reduce the incidence of hypertension” Effect of a Salt Substitute on Incid…

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Seba GZ, MD, MSc

@sebagz1 · X

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@ShawnRadcliffe · X

RT @VipsMDMEd: “replacing usual salt with a salt substitute may reduce the incidence of hypertension” Effect of a Salt Substitute on Incid…

Feb 13, 2024 · 2 shares · 1,443 followers View post →

John Damianos, M.D.

@john_damianosMD · X

Feb 13, 2024 · 10 likes · 2 shares · 23,783 followers View post →

Spelunking

@Spelunking3 · X

RT @EricTopol: A randomized trial of a salt substitute vs usual salt intake in people (mean age 71, Chinese population) with normal blood p…

Feb 13, 2024 · 163 shares · 16 followers View post →

Prof. Nasser Alzerwi

@NAlzerwi · X

RT @EricTopol: A randomized trial of a salt substitute vs usual salt intake in people (mean age 71, Chinese population) with normal blood p…

Feb 13, 2024 · 163 shares · 1,732 followers View post →

MatJou

@mat_jou · X

RT @EricTopol: A randomized trial of a salt substitute vs usual salt intake in people (mean age 71, Chinese population) with normal blood p…

Feb 13, 2024 · 163 shares · 54 followers View post →

leroyvanderberg

@physiquecheck · X

RT @EricTopol: A randomized trial of a salt substitute vs usual salt intake in people (mean age 71, Chinese population) with normal blood p…

Feb 13, 2024 · 163 shares · 11 followers View post →

Betty C. Jung

@bettycjung.bsky.social · Bluesky

Effect of a Salt Substitute on Incidence of Hypertension and Hypotension Among Normotensive Adults www.jacc.org/doi/10.1016/...

Feb 13, 2024 · 1 like · 2 shares View post →

Benjamin Vipler, MD, MEd

@VipsMDMEd · X

Feb 13, 2024 · 12 likes · 2 shares · 6,312 followers View post →

trader

@trader363 · X

RT @drjkahn: Effect of a Salt Substitute on Incidence of Hypertension and Hypotension Among Normotensive Adults | Journal of the American C…

Feb 13, 2024 · 1 share · 373 followers View post →

Joel "Heart Prevention" Kahn MD, FACC

@drjkahn · X

Effect of a Salt Substitute on Incidence of Hypertension and Hypotension Among Normotensive Adults | Journal of the American College of Cardiology https://t.co/QIhTGZweeN

Feb 13, 2024 · 3 likes · 1 share · 32,288 followers View post →

Oscar Mendiz

@omendiz · X

Reemplazar la sal

Feb 13, 2024 · 5 likes · 8,675 followers View post →

Javier Sobrino Martinez

@jsobrinom · X

Effect of a Salt Substitute on Incidence of Hypertension and Hypotension. https://t.co/n7uhqAjjCF @SEHLELHA140_90 @secardiologia @catcardio @CatalanaHTA https://t.co/VxFcc2WejH

Feb 13, 2024 · 7 likes · 4 shares · 344 followers View post →

Prof. Dr. Sanjeev Bagai

@BagaiDr · X

Effect of a Salt Substitute on Incidence of Hypertension and Hypotension Among Normotensive Adults | Journal of American College of Cardiology. salt substitute group had⬇️hypertension incidence (11.7 vs 24.3/ 100 person-years; aHR: 0.60; P = 0.02) https://t.co/CeJ15HvXSd

Feb 12, 2024 · 1 like · 34,758 followers View post →

Effect of a Salt Substitute on Incidence of Hypertension and Hypotension Among Normotensive Adults.

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Salt Substitution for Blood Pressure Prevention Based on Scientific Evidence