Nutrients February 2024 PMID 38398881

The Impact of Glucomannan, Inulin, and Psyllium Supplementation (Soloways) on Weight Loss in Adults with FTO, LEP, LEPR, and MC4R Polymorphisms: A Randomized, Double-Blind, Placebo-Controlled Trial.

Evgeny Pokushalov, Andrey Ponomarenko, Claire Garcia, Inessa Pak, Evgenya Shrainer, Mariya Seryakova, Michael Johnson, Richard Miller

Download social card

Mentions

Peak: 2 in Dec 2025

across 3 sources since Jun 2024

Extended reach

94,125

potential audience

Total likes

4,659

Video views

93,089

Mentions per month

Jun 2024 – Dec 2025

Where it's discussed

X / Twitter2 posts
YouTube2 videos
Instagram1 posts

AI synopsis

What people are saying

The discussions highlight that the dietary supplement combining glucomannan, inulin, and psyllium is portrayed as effective for weight loss and body composition improvement, especially in individuals with certain genetic variations. The tone emphasizes effectiveness and benefits, which underscores a positive perception of the research’s implications.

AgreementStrong agreement

Both discussions strongly agree that the dietary supplements are effective for weight loss and improve body composition, indicating widespread support for the findings.

InterestHigh interest

The posts demonstrate high interest, focusing on specific benefits and genetic aspects, showing active engagement with the research implications.

EngagementModerate engagement

The discussions are somewhat detailed, mentioning genetic polymorphisms and physiological improvements, which reflects moderate but not deep engagement.

ImpactModerate impact

The emphasis on positive outcomes suggests that the discussions see the study's results as potentially impactful, especially for obese individuals considering supplements.

Abstract in brief

This study tested whether taking a fiber supplement made of glucomannan, inulin, and psyllium helps with weight loss in obese adults who have certain genetic variations (polymorphisms) in the FTO, LEP, LEPR, or MC4R genes.
Results showed that those who took the fiber supplement experienced notable reductions in body weight, BMI, fat mass, and visceral fat compared to those who took a placebo, with greater effects observed in carriers of the minor alleles of the genes.
However, the fiber supplement was associated with a high rate of gastrointestinal side effects, affecting about 74.6% of participants in the treatment group, while the placebo group had no reported side effects.

Read the full abstract

All mentions

How Persistent Organic Pollutants Impact Obesity and Health Risks

Persistent organic pollutants (POPs) are accumulated in fat tissue and linked to health issues. Understanding their role in obesity can explain paradoxical effects of weight loss and potential protective benefits…

Dr. med. Ulrich Selz · Dec 28, 2025 53,076 views

Enhancing Body Composition through Time-Restricted Eating in Young Males

A 6-week time-restricted eating regimen led to improved body composition and increased basal fat oxidation in young men, without enhancing fat oxidation during exercise, indicating benefits in resting metabolic state.

Dr. med. Ulrich Selz · Dec 29, 2025 40,013 views

R. Cassar, MSc

@ReCass_ · X

RT @doutorsaude_: A suplementação dietética com glucomanano, inulina e psyllium promove eficazmente a perda de peso e melhora a composição…

Jul 29, 2024 · 1 share · 199 followers View post →

Dr.Roberto Fr Amaral

@doutorsaude_ · X

Jun 30, 2024 · 1 like · 1 share · 824 followers View post →

Fahed Khalid AlYehya | ‎السلام عليكم ورحمة الله وبركاته ✌️‎ | Instagram

Instagram

This content may be inappropriate. It's unavailable for certain audiences. Log in to continue. Open Instagram.

May 20, 2025 View →