Front Psychiatry February 2024 PMID 38426002

Efficacy and acceptability of psilocybin for primary or secondary depression: A systematic review and meta-analysis of randomized controlled trials.

Shuping Fang, Xin Yang, Wei Zhang

Mentions

17
Peak: 9 in Feb 2024
across 2 sources since Feb 2024

Extended reach

114,080
potential audience

Total likes

209

Video views

6,068

Mentions per month

Feb 2024 – Mar 2025

Where it's discussed

  • X / Twitter14 posts
  • YouTube3 videos

AI synopsis

What people are saying

The collective discussions reflect optimism about psilocybin's antidepressant effects, with phrases like 'promising' and mentions of 'large positive effects,' indicating their recognition of research significance. Words such as 'acceptability' and 'efficacy' along with references to recent meta-analyses contribute to the perception of impactful scientific findings, while some comments show curiosity about safety and future studies.

AgreementModerate agreement

Most discussions acknowledge the positive findings of the meta-analysis, with some explicitly supporting the therapeutic potential of psilocybin for depression.

InterestHigh interest

The discussions demonstrate high interest, highlighting the significance of recent research, with posts referencing new studies and their implications.

EngagementModerate engagement

Participants show moderate engagement, with some summarizing key points and considering clinical relevance, though few delve deeply into methodological details.

ImpactModerate impact

The discussions hint at the potential influence of these findings for mental health treatment, though they remain cautious about fully endorsing widespread use at this stage.

Abstract in brief

  • Psilocybin has been shown to have significant antidepressant effects in recent studies, especially in treating both primary and depression related to severe illnesses, with larger doses producing better results.
  • The meta-analysis of 8 studies with 524 adults found a large positive effect of psilocybin on depression, and its side effects are usually temporary, although serious adverse events can happen.
  • Overall, psilocybin appears to be a promising short-term and long-term treatment for depression, but more research is needed to fully understand its therapeutic potential and safety profile.

Top posts

Most liked on X and Bluesky
Julie Holland, MD
@BellevueDoc · X

Efficacy and acceptability of psilocybin for primary or secondary depression: a systematic review and meta-analysis of randomized controlled trials https://t.co/4BS5x8dwdu

Feb 17, 2024 · 18 likes · 4 shares · 14,595 followers View post →
Frontiers - Psychiatry
@FrontPsychiatry · X

New Research: Efficacy and acceptability of psilocybin for primary or secondary depression: A systematic review and meta-analysis of randomized controlled trials: Introduction Psilocybin is a classic psychedelics, which has been shown to… https://t.co/Shpm1UoK9p #Psychiatry

Feb 15, 2024 · 4 likes · 16,548 followers View post →
Julie Holland, MD
@BellevueDoc · X

Efficacy and acceptability of psilocybin for primary or secondary depression https://t.co/Zne83IhBEC

Feb 29, 2024 · 2 likes · 2 shares · 14,595 followers View post →
THERADELICS
@theradelics · X

Efficacy and acceptability of psilocybin for primary or secondary depression: A systematic review and meta-analysis of randomized controlled trials https://t.co/qzALojxu0E https://t.co/CFjGNU7K5c

Mar 1, 2024 · 1 like · 3,382 followers View post →
THERADELICS
@theradelics · X

Efficacy and acceptability of psilocybin for primary or secondary depression: A systematic review and meta-analysis of randomized controlled trials https://t.co/PmvO8Dpob9 https://t.co/pqNMigrfrI

Mar 1, 2024 · 1 like · 3,382 followers View post →
Agingdoc
@agingdoc1 · X

Efficacy and acceptability of psilocybin for primary or secondary depression: A systematic review and meta-analysis of randomized controlled trials https://t.co/N3eRxmm33e

Oct 3, 2024 · 1 share · 42,372 followers View post →

All mentions

Thomas Reilly
@Rational_Psych · X

Efficacy and acceptability of psilocybin for primary or secondary depression: A systematic review and meta-analysis of randomized controlled trials https://t.co/bxkTqJsr1U

Nov 6, 2024 · 1,310 followers View post →
Mind Your Science!
@MindYourSci · X

RT @agingdoc1: Efficacy and acceptability of psilocybin for primary or secondary depression: A systematic review and meta-analysis of rando…

Oct 3, 2024 · 1 share · 132 followers View post →
Agingdoc
@agingdoc1 · X

Efficacy and acceptability of psilocybin for primary or secondary depression: A systematic review and meta-analysis of randomized controlled trials https://t.co/N3eRxmm33e

Oct 3, 2024 · 1 share · 42,372 followers View post →
THERADELICS
@theradelics · X

Efficacy and acceptability of psilocybin for primary or secondary depression: A systematic review and meta-analysis of randomized controlled trials https://t.co/PmvO8Dpob9 https://t.co/pqNMigrfrI

Mar 1, 2024 · 1 like · 3,382 followers View post →
THERADELICS
@theradelics · X

Efficacy and acceptability of psilocybin for primary or secondary depression: A systematic review and meta-analysis of randomized controlled trials https://t.co/qzALojxu0E https://t.co/CFjGNU7K5c

Mar 1, 2024 · 1 like · 3,382 followers View post →
Sir Gunjah LimpsAlot
@SLimpsalot · X

RT @BellevueDoc: Efficacy and acceptability of psilocybin for primary or secondary depression https://t.co/Zne83IhBEC

Feb 29, 2024 · 2 shares · 443 followers View post →
eksogen
@eksogenisk · X

RT @BellevueDoc: Efficacy and acceptability of psilocybin for primary or secondary depression https://t.co/Zne83IhBEC

Feb 29, 2024 · 2 shares · 1,946 followers View post →
Julie Holland, MD
@BellevueDoc · X

Efficacy and acceptability of psilocybin for primary or secondary depression https://t.co/Zne83IhBEC

Feb 29, 2024 · 2 likes · 2 shares · 14,595 followers View post →
eksogen
@eksogenisk · X

RT @BellevueDoc: Efficacy and acceptability of psilocybin for primary or secondary depression: a systematic review and meta-analysis of ran…

Feb 17, 2024 · 4 shares · 1,946 followers View post →
LongCovidPNW
@longcovidpnw · X

RT @BellevueDoc: Efficacy and acceptability of psilocybin for primary or secondary depression: a systematic review and meta-analysis of ran…

Feb 17, 2024 · 4 shares · 1,688 followers View post →
Bruce Waynejrv
@Bob_Stinson1234 · X

RT @BellevueDoc: Efficacy and acceptability of psilocybin for primary or secondary depression: a systematic review and meta-analysis of ran…

Feb 17, 2024 · 4 shares · 5,176 followers View post →
Sir Gunjah LimpsAlot
@SLimpsalot · X

RT @BellevueDoc: Efficacy and acceptability of psilocybin for primary or secondary depression: a systematic review and meta-analysis of ran…

Feb 17, 2024 · 4 shares · 443 followers View post →
Julie Holland, MD
@BellevueDoc · X

Efficacy and acceptability of psilocybin for primary or secondary depression: a systematic review and meta-analysis of randomized controlled trials https://t.co/4BS5x8dwdu

Feb 17, 2024 · 18 likes · 4 shares · 14,595 followers View post →
Frontiers - Psychiatry
@FrontPsychiatry · X

New Research: Efficacy and acceptability of psilocybin for primary or secondary depression: A systematic review and meta-analysis of randomized controlled trials: Introduction Psilocybin is a classic psychedelics, which has been shown to… https://t.co/Shpm1UoK9p #Psychiatry

Feb 15, 2024 · 4 likes · 16,548 followers View post →