Obes Rev May 2024 PMID 38463003

Potent incretin-based therapy for obesity: A systematic review and meta-analysis of the efficacy of semaglutide and tirzepatide on body weight and waist circumference, and safety.

Alberte Laura Oest Müllertz, Rasmus Michael Sandsdal, Simon Birk Kjær Jensen, Signe Sørensen Torekov

Mentions

6
Peak: 2 in Mar 2024
across 3 sources since Mar 2024

Extended reach

53,164
potential audience

Total likes

1,124

Video views

33,584

Mentions per month

Mar 2024 – Jan 2025

Where it's discussed

  • X / Twitter2 posts
  • YouTube2 videos
  • Instagram2 posts

AI synopsis

What people are saying

Several comments highlight the significance of the research, with phrases like 'powerful options for obesity treatment' and 'manageable side effects' pointing to the article’s potential impact, while interest in the specifics of drug effects and safety is evident in references to 'waist size reduction' and 'mild gastrointestinal side effects.' The tone is analytical yet optimistic, reflecting a balanced appreciation of the study's findings.

AgreementModerate agreement

Most discussions acknowledge the validity of the review, with some emphasizing the promising efficacy of semaglutide and tirzepatide in weight loss, reflecting general agreement.

InterestModerate interest

Posts show moderate curiosity, often referencing the potential of these medications for obesity treatment, suggesting a shared interest but not intense enthusiasm.

EngagementModerate engagement

The posts demonstrate active engagement by mentioning specific outcomes like waist circumference reduction and safety profiles, indicating thoughtful participation.

ImpactModerate impact

The discussions highlight the potential of these therapies to influence obesity management practices, suggesting a modest but meaningful impact.

Abstract in brief

  • This study reviews how effective and safe two medications, semaglutide and tirzepatide, are for weight loss in people without diabetes, showing both drugs significantly reduce body weight and waist size.
  • Ttirzepatide appeared slightly more effective than semaglutide in weight and waist circumference reduction, with mostly mild gastrointestinal side effects that decreased over time, indicating good tolerability.
  • The findings suggest that weekly injections of these drugs can be powerful options for obesity treatment with manageable side effects.

Top posts

Most liked on X and Bluesky
Simon Jensen
@SBKJensen · X

Potent incretin‐based therapy for obesity: A systematic review and meta‐analysis of the efficacy of semaglutide and tirzepatide on body weight and waist circumference, and safety - Müllertz - Obesity Reviews - Wiley Online Library https://t.co/tcpsyvfPEK

Mar 11, 2024 · 1 like · 32 followers View post →
Nick Krontiris
@nick_krontiris · X

Potent incretin-based therapy for obesity: A systematic review and meta-analysis of the efficacy of semaglutide and tirzepatide on body weight and waist circumference, and safety (open access) https://t.co/cA2pPtGF1u

Mar 14, 2024 · 19,529 followers View post →

All mentions

Nick Krontiris
@nick_krontiris · X

Potent incretin-based therapy for obesity: A systematic review and meta-analysis of the efficacy of semaglutide and tirzepatide on body weight and waist circumference, and safety (open access) https://t.co/cA2pPtGF1u

Mar 14, 2024 · 19,529 followers View post →
Simon Jensen
@SBKJensen · X

Potent incretin‐based therapy for obesity: A systematic review and meta‐analysis of the efficacy of semaglutide and tirzepatide on body weight and waist circumference, and safety - Müllertz - Obesity Reviews - Wiley Online Library https://t.co/tcpsyvfPEK

Mar 11, 2024 · 1 like · 32 followers View post →
Vitor Nuto CRM: 13299/PB - 236279/SP - 12359/RN - Instagram
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vitornuto Vitor Nuto CRM: 13299/PB - 236279/SP - 12359/RN . Referências: doi:10.1016/S2213-8587(19)30249-9 doi:10.1111/obr.13717 doi:10.1007/ ...

Dec 2, 2024 View →
Vitor Nuto CRM: 13299/PB - 236279/SP - 12359/RN . Referências ...
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... 12359/RN . Referências: doi:10.1016/S2213-8587(19)30249-9 doi:10.1111/obr.13717 doi:10.1007/s00125-024-06144-1".

Oct 3, 2024 View →