Aging Cell June 2024 PMID 38500398

Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function in aged mice.

Zachary J Fennel, Paul-Emile Bourrant, Anu Susan Kurian, Jonathan J Petrocelli, Naomi M M P de Hart, Elena M Yee, Sihem Boudina, Hans S Keirstead, Gabrielle Nistor, Scott A Greilach, Nicole C Berchtold, Thomas E Lane, Micah J Drummond

Mentions

69
Peak: 24 in Mar 2024
across 5 sources since Mar 2024

Extended reach

177,832
potential audience

Total likes

623

Video views

12,776

Mentions per month

Mar 2024 – Aug 2025

Where it's discussed

  • X / Twitter46 posts
  • News15 articles
  • YouTube3 videos
  • Blogs3 articles
  • Facebook2 posts

AI synopsis

What people are saying

The discussions often highlighted the potential of stem cell secretome treatment in redefining approaches to age-related health issues, with posts mentioning phrases like 'game changer' and 'rejuvenation therapy' reflecting excitement. Comments about specific research projects targeting the immune system illustrate a deeper interest in the implications of the findings, enhancing the perceived significance and urgency surrounding this area of research.

AgreementModerate agreement

The majority of discussions reflect a supportive stance toward the publication's findings, indicating general consensus on its significance.

InterestHigh interest

Many participants express strong interest in the research, noting its relevance and potential for advancing medical science.

EngagementModerate engagement

While there are various references to the study, the depth of discussion is moderate, with some users elaborating on the implications.

ImpactHigh impact

Users perceive the publication as having substantial implications for future research and therapies, emphasizing its potential to influence health outcomes.

Abstract in brief

  • Aging leads to muscle loss, increased fat, and reduced physical function, prompting research into interventions like stem cell secretome treatment.
  • A 4-week study on aged male mice showed that secretome injections improved lean mass and physical performance, with significant changes in muscle structure and fat size.
  • The secretome enhanced muscle cell growth and reduced fat storage, indicating its potential to improve overall metabolism and health in older individuals.

Top posts

Most liked on X and Bluesky
Aging Science News
@AgingBiology · X

Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function in aged mice https://t.co/dVbbO6MfD6

Apr 15, 2024 · 54 likes · 14 shares · 30,584 followers View post →
Zachary Fennel
@zfennel · X

Very excited to share our new publication @drummond_lab. Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function in aged mice. Check it out now in @Aging_Cell #myotwitter https://t.co/mBIobS9jOb

Mar 19, 2024 · 24 likes · 7 shares · 188 followers View post →
Agingdoc
@agingdoc1 · X

Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function in aged mice | @Aging_Cell https://t.co/G09lGgQrH7 https://t.co/kRCMCiDvfU

Mar 25, 2024 · 20 likes · 3 shares · 41,648 followers View post →
Rasmussen Lab
@TheRasmussenLab · X

Nice work from the Drummond Lab _— Stem cell secretome treatment improves whole‐body metabolism, reduces adiposity, and promotes skeletal muscle function in aged mice - Fennel - Aging Cell - Wiley Online Library https://t.co/zqNIfC1Skg

Mar 19, 2024 · 18 likes · 4 shares · 426 followers View post →
Agingdoc
@agingdoc1 · X

Stem cell secretome treatment improves whole‐body metabolism, reduces adiposity, and promotes skeletal muscle function in aged mice https://t.co/FWI91SOTvu https://t.co/IOsjSmMJP3

Mar 27, 2024 · 9 likes · 1 share · 41,648 followers View post →
Chris Linnell
@ChrisPollyanna1 · X

Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function in aged mice 2/3 https://t.co/KTQjp0jwxr

Mar 19, 2024 · 4 likes · 1 share · 700 followers View post →

All mentions

Kali the destroyer
@athena369123 · X

The Most Promising Rejuvenation Therapy Now In Clinical Trials | Dr Hans... https://t.co/RxM5T9HOtH via @YouTube

Aug 13, 2025 · 1 like · 66 followers View post →
Tyler Moore
@TylerMo41608321 · X

@LidskyPeter I watched some of your presentations, and you think the immune system is the best place to intervene. What are the most promising research-projects that pursue this in your opinion? Thymus rejuvenation? Immune system secretomes - https://t.co/y1HeMS9RH4

Jan 20, 2025 · 1 like · 111 followers View post →
Orlando_uy
@Orlando_uy · X

Stem cell secretome treatment improves whole‐body metabolism, reduces adiposity, and promotes skeletal muscle function in aged mice. https://t.co/HFBviZQOUb

May 31, 2024 · 2 likes · 693 followers View post →
Longevity
@LongevityTao · X

The Most Promising Rejuvenation Therapy Now In Clinical Trials | Dr Hans... https://t.co/SEyv8H0pAc

May 18, 2024 · 330 followers View post →
Nunzio Cuzzucoli
@NunzioCuzzucoli · X

The Most Promising Rejuvenation Therapy Now In Clinical Trials | Dr Hans... https://t.co/6V8SCNkEZT via @YouTube even the theory of aging that originates from the immune system has cellular theft as its main cause. in this study cells from the immune system are added to modulate.

May 16, 2024 · 3 likes · 75 followers View post →
ModernHealthspan
@MHealthspan · X

We would like to thank @drhanskeirstead for coming on our channel to talk about the amazing work he is doing with the secretome of stem cells to rejuvenate the immune system at Immunis Biomedical. Interview is now on the channel https://t.co/56t1GInyIv https://t.co/iGSiu1dgnz

May 16, 2024 · 1 like · 721 followers View post →
P123
@P1231032850 · X

The Most Promising Rejuvenation Therapy Now In Clinical Trials | https://t.co/sfFrMnJXlA

May 15, 2024 · 3,213 followers View post →
Diana Mota
@DianaMota_Toro · X

RT @AgingBiology: Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function…

Apr 16, 2024 · 14 shares · 116 followers View post →
Parinya Samakkarnthai
@Samakkarnthai · X

RT @AgingBiology: Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function…

Apr 16, 2024 · 14 shares · 514 followers View post →
luis hernan graffe
@hernangraffe · X

RT @AgingBiology: Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function…

Apr 16, 2024 · 14 shares · 3,140 followers View post →
Sahba Ferdowsi DO (conciergedoc)
@DrFerdowsi · X

RT @AgingBiology: Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function…

Apr 16, 2024 · 14 shares · 9,645 followers View post →
Aging and Disease
@ISOAD2018 · X

RT @AgingBiology: Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function…

Apr 16, 2024 · 14 shares · 89 followers View post →
AngryPhDstudent❗️❗️❗️
@ONNESHA092 · X

RT @AgingBiology: Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function…

Apr 16, 2024 · 14 shares · 183 followers View post →
Wei Roc Song
@WeiRocSong · X

RT @AgingBiology: Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function…

Apr 16, 2024 · 14 shares · 97 followers View post →
YMED-X
@YmedX269 · X

RT @AgingBiology: Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function…

Apr 16, 2024 · 14 shares · 229 followers View post →
Xavier Contreras
@Contreras_Xav · X

RT @AgingBiology: Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function…

Apr 16, 2024 · 14 shares · 33 followers View post →
is a silly ghoul
@yee_som · X

RT @AgingBiology: Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function…

Apr 16, 2024 · 14 shares · 119 followers View post →
System
@liyongcsco12 · X

RT @AgingBiology: Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function…

Apr 16, 2024 · 14 shares · 64 followers View post →
André Katayama Yamada
@KatayamaYamada · X

RT @AgingBiology: Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function…

Apr 15, 2024 · 14 shares · 404 followers View post →
Lisa Vlad
@LisaVlad2 · X

RT @AgingBiology: Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function…

Apr 15, 2024 · 14 shares · 108 followers View post →
Aging Science News
@AgingBiology · X

Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function in aged mice https://t.co/dVbbO6MfD6

Apr 15, 2024 · 54 likes · 14 shares · 30,584 followers View post →
H.Diah
@N_diah453 · X

RT @zfennel: Very excited to share our new publication @drummond_lab. Stem cell secretome treatment improves whole-body metabolism, reduc…

Apr 11, 2024 · 7 shares · 6 followers View post →
Mind Your Science!
@MindYourSci · X

RT @agingdoc1: Stem cell secretome treatment improves whole‐body metabolism, reduces adiposity, and promotes skeletal muscle function in ag…

Mar 28, 2024 · 1 share · 132 followers View post →
INSPIRE Platform - IHU HealthAge
@INSPIREPlatfor1 · X

After 4 weeks "Stem cell secretome treatment improves whole‐body metabolism, reduces adiposity, and promotes skeletal muscle function in aged mice." https://t.co/xUvpPI5bRL @brunovellas @isaperarnau @RestoreInstitut @InfinityTLS @I2mcT

Mar 28, 2024 · 1 like · 674 followers View post →
Kelly A. Hogan Ph.D.
@Loose_Lab_Rat · X

Stem cell secretome treatment improves whole‐body metabolism, reduces adiposity, and promotes skeletal muscle function in aged mice https://t.co/5KHDxaZO6K

Mar 27, 2024 · 1 like · 2,240 followers View post →
Agingdoc
@agingdoc1 · X

Stem cell secretome treatment improves whole‐body metabolism, reduces adiposity, and promotes skeletal muscle function in aged mice https://t.co/FWI91SOTvu https://t.co/IOsjSmMJP3

Mar 27, 2024 · 9 likes · 1 share · 41,648 followers View post →
AngryPhDstudent❗️❗️❗️
@ONNESHA092 · X

RT @agingdoc1: Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function in ag…

Mar 25, 2024 · 3 shares · 183 followers View post →
Bayar Jaff
@JaffBayar · X

RT @agingdoc1: Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function in ag…

Mar 25, 2024 · 3 shares · 605 followers View post →
john morley
@drjohnmorley · X

Stem cell secretome treatment improves whole‐body metabolism, reduces adiposity, and promotes skeletal muscle function in aged mice - Fennel - Aging Cell - Wiley Online Library https://t.co/sfnn5weMWb

Mar 25, 2024 · 8,318 followers View post →
NADIA EB
@NADYEUGENY · X

RT @agingdoc1: Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function in ag…

Mar 25, 2024 · 3 shares · 215 followers View post →
Agingdoc
@agingdoc1 · X

Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function in aged mice | @Aging_Cell https://t.co/G09lGgQrH7 https://t.co/kRCMCiDvfU

Mar 25, 2024 · 20 likes · 3 shares · 41,648 followers View post →
Micah Drummond
@drummond_lab · X

RT @zfennel: Very excited to share our new publication @drummond_lab. Stem cell secretome treatment improves whole-body metabolism, reduc…

Mar 21, 2024 · 7 shares · 603 followers View post →
Nunzio Cuzzucoli
@NunzioCuzzucoli · X

RT @ChrisPollyanna1: Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function…

Mar 20, 2024 · 1 share · 75 followers View post →
Jeremy B. Ducharme
@JDucharme_PhD · X

RT @zfennel: Very excited to share our new publication @drummond_lab. Stem cell secretome treatment improves whole-body metabolism, reduc…

Mar 20, 2024 · 7 shares · 94 followers View post →
Manoj Mayogi Mishra
@mayogisense · X

RT @TheRasmussenLab: Nice work from the Drummond Lab _— Stem cell secretome treatment improves whole‐body metabolism, reduces adiposity, an…

Mar 19, 2024 · 4 shares · 572 followers View post →
TimePie (focus on anti-aging science)
@TimePieChina · X

Intramuscular treatment with a #stem cell secretome improves whole-body metabolism, physical function, and remodels skeletal muscle and adipose tissue in #aged mice.

Mar 19, 2024 · 2 likes · 695 followers View post →
Jonathan Petrocelli
@JJPetrocelli · X

RT @zfennel: Very excited to share our new publication @drummond_lab. Stem cell secretome treatment improves whole-body metabolism, reduc…

Mar 19, 2024 · 7 shares · 169 followers View post →
Stewart Jeromson
@StewartJeromson · X

RT @TheRasmussenLab: Nice work from the Drummond Lab _— Stem cell secretome treatment improves whole‐body metabolism, reduces adiposity, an…

Mar 19, 2024 · 4 shares · 406 followers View post →
Jake Mey, PhD, RD
@CakeNutrition · X

RT @TheRasmussenLab: Nice work from the Drummond Lab _— Stem cell secretome treatment improves whole‐body metabolism, reduces adiposity, an…

Mar 19, 2024 · 4 shares · 8,637 followers View post →
Katsu Funai
@KatsuFunai · X

RT @zfennel: Very excited to share our new publication @drummond_lab. Stem cell secretome treatment improves whole-body metabolism, reduc…

Mar 19, 2024 · 7 shares · 3,880 followers View post →
Chris Linnell
@ChrisPollyanna1 · X

Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function in aged mice 2/3 https://t.co/KTQjp0jwxr

Mar 19, 2024 · 4 likes · 1 share · 700 followers View post →
Zach McKenna
@ZachMcKenna_PhD · X

RT @zfennel: Very excited to share our new publication @drummond_lab. Stem cell secretome treatment improves whole-body metabolism, reduc…

Mar 19, 2024 · 7 shares · 100 followers View post →
Zachary Fennel
@zfennel · X

Very excited to share our new publication @drummond_lab. Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function in aged mice. Check it out now in @Aging_Cell #myotwitter https://t.co/mBIobS9jOb

Mar 19, 2024 · 24 likes · 7 shares · 188 followers View post →
Brian Hodge
@Brian_Hodge_ · X

RT @TheRasmussenLab: Nice work from the Drummond Lab _— Stem cell secretome treatment improves whole‐body metabolism, reduces adiposity, an…

Mar 19, 2024 · 4 shares · 1,283 followers View post →
Rasmussen Lab
@TheRasmussenLab · X

Nice work from the Drummond Lab _— Stem cell secretome treatment improves whole‐body metabolism, reduces adiposity, and promotes skeletal muscle function in aged mice - Fennel - Aging Cell - Wiley Online Library https://t.co/zqNIfC1Skg

Mar 19, 2024 · 18 likes · 4 shares · 426 followers View post →
University of Utah Microbiology & Immunology
@UofUMandI · X

Stem cell secretome treatment improves whole-body metabolism, reduces adiposity, and promotes skeletal muscle function in aged mice https://t.co/in0NUMT4ww

Mar 19, 2024 · 464 followers View post →