Contemp Clin Trials June 2024 PMID 38547961

Tirzepatide for the treatment of obstructive sleep apnea: Rationale, design, and sample baseline characteristics of the SURMOUNT -OSA phase 3 trial.

Atul Malhotra, Josef Bednarik, Sujatro Chakladar, Julia P Dunn, Terri Weaver, Ron Grunstein, Ingo Fietze, Susan Redline, Ali Azarbarzin, Scott A Sands, Richard J Schwab, Mathijs C Bunck

Mentions

36
Peak: 3 in Jun 2024
across 3 sources since Jun 2024

Extended reach

33,272
potential audience

Total likes

5

Video views

219

Mentions per month

Jun 2024 – Sep 2025

Where it's discussed

  • News28 articles
  • X / Twitter6 posts
  • YouTube2 videos

AI synopsis

What people are saying

The overall sentiment reflects mild interest and engagement, exemplified by comments like '@blueeyedboy88 Mam bezdech ale czytałam' which shows personal health relevance, and mentions of the publication's design and baseline characteristics, indicating a basic level of engagement. The tone is neutral and informational, with some users indicating a desire to learn more, but overall, the discussions suggest cautious recognition rather than strong enthusiasm or skepticism.

AgreementNeither agree nor disagree

Most discussions appear to acknowledge the study's importance or mention it factually, without strong disagreement or critique.

InterestModerate interest

Participants show some curiosity about the subject, responding with brief mentions of their experiences or plans to read more.

EngagementModerate engagement

Comments include references to personal health impacts and mentions of the study's design, indicating moderate active participation.

ImpactModerate impact

The discussions suggest an awareness of potential implications for treatment of sleep apnea, though few details indicate deep concern or widespread change.

Abstract in brief

  • The study examines the effectiveness and safety of tirzepatide in treating moderate to severe obstructive sleep apnea (OSA) in individuals with obesity, as traditional weight loss methods can be difficult.
  • The SURMOUNT-OSA trial is a randomized and placebo-controlled phase 3 study that includes 469 participants, with some receiving no current OSA treatment and others using positive airway pressure therapy, while all are also undergoing lifestyle interventions for weight reduction.
  • The primary outcome measures the difference in apnea hypopnea index after 52 weeks between the tirzepatide and placebo groups, alongside various secondary outcomes related to sleep quality, physical activity, and cardiometabolic health.

Top posts

Most liked on X and Bluesky
Obesidades México
@Obesidades_mx · X

@ConscienHealth -Malhotra A, et al. Tirzepatide for the treatment of obstructive sleep apnea: Rationale, design, and sample baseline characteristics of the SURMOUNT-OSA phase 3 trial. Contemp Clin Trials. 2024.

Dec 27, 2024 · 2 likes · 1 share · 1,336 followers View post →
ScienceGeekAI
@ScienceGeekAI · X

@bfialek Cierpię to czytałem https://t.co/kYwao4mqMx

Jun 24, 2024 · 1 like · 983 followers View post →
redGDPS Diabetes
@redGDPS · X

Bibliografía en @PubMedOnline Tirzepatide for the treatment of obstructive sleep apnea: Rationale, design, and sample baseline characteristics of the SURMOUNT -OSA phase 3 trial Atul Malhotra et al. Contemp Clin Trials. 2024 Jun. https://t.co/Hm7RwgRgL7

Jun 23, 2024 · 15,542 followers View post →
Ted Kyle
@ConscienHealth · X

RT @Obesidades_mx: @ConscienHealth -Malhotra A, et al. Tirzepatide for the treatment of obstructive sleep apnea: Rationale, design, and sam…

Dec 27, 2024 · 1 share · 11,444 followers View post →
William Lagakos
@caloriesproper2 · X

Tirzepatide for the treatment of obstructive sleep apnea: Rationale, design, and sample baseline characteristics of the SURMOUNT -OSA phase 3 trial https://t.co/Nchel08Az6

Dec 21, 2024 · 2,761 followers View post →
ScienceGeekAI
@ScienceGeekAI · X

@blueeyedboy88 Mam bezdech ale … czytałem https://t.co/kYwao4mqMx

Jun 26, 2024 · 983 followers View post →

All mentions

Ted Kyle
@ConscienHealth · X

RT @Obesidades_mx: @ConscienHealth -Malhotra A, et al. Tirzepatide for the treatment of obstructive sleep apnea: Rationale, design, and sam…

Dec 27, 2024 · 1 share · 11,444 followers View post →
Obesidades México
@Obesidades_mx · X

@ConscienHealth -Malhotra A, et al. Tirzepatide for the treatment of obstructive sleep apnea: Rationale, design, and sample baseline characteristics of the SURMOUNT-OSA phase 3 trial. Contemp Clin Trials. 2024.

Dec 27, 2024 · 2 likes · 1 share · 1,336 followers View post →
William Lagakos
@caloriesproper2 · X

Tirzepatide for the treatment of obstructive sleep apnea: Rationale, design, and sample baseline characteristics of the SURMOUNT -OSA phase 3 trial https://t.co/Nchel08Az6

Dec 21, 2024 · 2,761 followers View post →
ScienceGeekAI
@ScienceGeekAI · X

@blueeyedboy88 Mam bezdech ale … czytałem https://t.co/kYwao4mqMx

Jun 26, 2024 · 983 followers View post →
ScienceGeekAI
@ScienceGeekAI · X

@bfialek Cierpię to czytałem https://t.co/kYwao4mqMx

Jun 24, 2024 · 1 like · 983 followers View post →
redGDPS Diabetes
@redGDPS · X

Bibliografía en @PubMedOnline Tirzepatide for the treatment of obstructive sleep apnea: Rationale, design, and sample baseline characteristics of the SURMOUNT -OSA phase 3 trial Atul Malhotra et al. Contemp Clin Trials. 2024 Jun. https://t.co/Hm7RwgRgL7

Jun 23, 2024 · 15,542 followers View post →