PubHawk
Exp Gerontol June 2024 PMID 38548241

Associations of infections and vaccines with Alzheimer's disease point to a role of compromised immunity rather than specific pathogen in AD.

Svetlana Ukraintseva, Arseniy P Yashkin, Igor Akushevich, Konstantin Arbeev, Hongzhe Duan, Galina Gorbunova, Eric Stallard, Anatoliy Yashin

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Mentions

22
Peak: 6 in Dec 2023
across 4 sources since Dec 2023

Extended reach

26,115
potential audience

Total likes

34

Video views

1,266

Mentions per month

Dec 2023 – Dec 2024

Where it's discussed

  • News10 articles
  • X / Twitter9 posts
  • YouTube2 videos
  • Bluesky1 posts

AI synopsis

What people are saying

The discussions reflect a general agreement with the article's emphasis on compromised immunity's role in AD, citing examples like increased AD risk linked to infections and the protective effects of vaccines. Words such as 'major role,' 'linked,' and 'risk' highlight a serious consideration of the findings' implications, while references to mechanisms and vaccines suggest a moderate level of engagement and impact in ongoing research and health policy debates.

AgreementModerate agreement

Most discussions support the idea that immunity plays a central role in AD, aligning with the article's conclusions.

InterestModerate interest

Posts show moderate curiosity, referencing specific findings and potential implications but not deeply exploring the mechanisms.

EngagementModerate engagement

Participants engage by sharing interpretations, citing related research, and discussing the significance of vaccination and infection history.

ImpactModerate impact

The collective tone recognizes the potential influence of these findings on future research and public health strategies.

Abstract in brief

  • Associations between infections, vaccines, and Alzheimer's disease (AD) suggest that weakened immunity, rather than specific pathogens, may increase vulnerability to infections that contribute to neurodegeneration.
  • The study found that infections like shingles, pneumonia, and mycoses between ages 65-75 were linked to higher AD risk, while vaccines against shingles and pneumonia reduced the risk, indicating potential protective effects.
  • These findings imply that vaccines like the pneumococcal and shingles vaccines might help prevent AD by boosting immune resilience, especially since infections seem more directly associated with AD compared to other dementias, highlighting the role of immunity in AD development.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Herpes Advocate
@HerpesAdvocate · X

Associations of infections and vaccines with Alzheimer's disease point to a major role of compromised immunity rather than specific pathogen in AD Findings revealed ….were linked to a higher AD risk later in life, increasing the risk by 16%-42%. https://t.co/sTXPvc8ZhL

Dec 19, 2023 · 8 likes · 3 shares · 1,695 followers View post →
Svetlana Ukraintseva
@aiyashin · X

Associations of infections and vaccines with Alzheimer's disease point to a role of compromised immunity rather tha… https://t.co/QHMXpsLLL8

Aug 31, 2024 · 3 likes · 4 followers View post →
二三四♫
@2u3v4w · X

@toshimizu7566 これはクリアーな結果ですね。接種資格を分ける誕生日1933/9/2前後で認知症の発症に差がある。 元論文のref.16でも帯状疱疹ワクチンでリスク低下。最近の研究も感染症やワクチンとの関連を示唆。興味深いです。 https://t.co/CKoz398KUd https://t.co/QAFQiCohZA https://t.co/lfJlj7978H

Jul 22, 2024 · 1 like · 571 followers View post →
medRxiv
@medrxivpreprint · X

Associations of infections and vaccines with Alzheimer's disease point to a major role of compromised immunity rather than specific pathogen in AD https://t.co/uwM94PgrY8 #medRxiv

Dec 5, 2023 · 17,469 followers View post →
AgeingUK
@AgeingUK · X

Associations of infections and vaccines with Alzheimer's disease point to a role of compromised immunity rather than specific pathogen in AD - ScienceDirect https://t.co/or9LXHnUBS (Interjection: perhaps being unwell is just generally a risk factor?) https://t.co/P5zLQGQHBQ

Apr 5, 2024 · 3,026 followers View post →
Herpes Advocate
@HerpesAdvocate · X

Associations of infections and vaccines with Alzheimer's disease point to a role of compromised... - https://t.co/SbNynoMLVI #ScholarAlerts

Mar 31, 2024 · 1,695 followers View post →

All mentions

Svetlana Ukraintseva
@aiyashin · X

Associations of infections and vaccines with Alzheimer's disease point to a role of compromised immunity rather tha… https://t.co/QHMXpsLLL8

Aug 31, 2024 · 3 likes · 4 followers View post →
二三四♫
@2u3v4w · X

@toshimizu7566 これはクリアーな結果ですね。接種資格を分ける誕生日1933/9/2前後で認知症の発症に差がある。 元論文のref.16でも帯状疱疹ワクチンでリスク低下。最近の研究も感染症やワクチンとの関連を示唆。興味深いです。 https://t.co/CKoz398KUd https://t.co/QAFQiCohZA https://t.co/lfJlj7978H

Jul 22, 2024 · 1 like · 571 followers View post →
AgeingUK
@AgeingUK · X

Associations of infections and vaccines with Alzheimer's disease point to a role of compromised immunity rather than specific pathogen in AD - ScienceDirect https://t.co/or9LXHnUBS (Interjection: perhaps being unwell is just generally a risk factor?) https://t.co/P5zLQGQHBQ

Apr 5, 2024 · 3,026 followers View post →
Herpes Advocate
@HerpesAdvocate · X

Associations of infections and vaccines with Alzheimer's disease point to a role of compromised... - https://t.co/SbNynoMLVI #ScholarAlerts

Mar 31, 2024 · 1,695 followers View post →
El Gran Mendoza
@gperezgonzalez · X

RT @HerpesAdvocate: Associations of infections and vaccines with Alzheimer's disease point to a major role of compromised immunity rather t…

Dec 20, 2023 · 3 shares · 144 followers View post →
Getoveryourself2176
@BabyLove57633 · X

RT @HerpesAdvocate: Associations of infections and vaccines with Alzheimer's disease point to a major role of compromised immunity rather t…

Dec 19, 2023 · 3 shares · 61 followers View post →
HSVadvocateLA
@HSVadvocateLA · X

RT @HerpesAdvocate: Associations of infections and vaccines with Alzheimer's disease point to a major role of compromised immunity rather t…

Dec 19, 2023 · 3 shares · 160 followers View post →
Herpes Advocate
@HerpesAdvocate · X

Associations of infections and vaccines with Alzheimer's disease point to a major role of compromised immunity rather than specific pathogen in AD Findings revealed ….were linked to a higher AD risk later in life, increasing the risk by 16%-42%. https://t.co/sTXPvc8ZhL

Dec 19, 2023 · 8 likes · 3 shares · 1,695 followers View post →
medRxivpreprint
@medrxivpreprint.bsky.social · Bluesky

Associations of infections and vaccines with Alzheimer's disease point to a major role of compromised immunity rather than specific pathogen in AD https://www.medrxiv.org/content/10.1101/2023.12.04.23299092v1

Dec 5, 2023 View post →
medRxiv
@medrxivpreprint · X

Associations of infections and vaccines with Alzheimer's disease point to a major role of compromised immunity rather than specific pathogen in AD https://t.co/uwM94PgrY8 #medRxiv

Dec 5, 2023 · 17,469 followers View post →