Class 1C antiarrhythmic drugs effectively suppressed PVCs in patients with NICM and ICDs, leading to increases in #LVEF and biventricular pacing percentage. In this limited sample, their use was safe. Larger studies are needed https://t.co/fMZfHz6wMa #JACCCEP #EPeeps #epICD https://t.co/wrtChulnlA
Class 1C Antiarrhythmics for Premature Ventricular Complex Suppression in Nonischemic Cardiomyopathy With Implantable Cardioverter-Defibrillators.
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Mar 2024 – Jul 2024Where it's discussed
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X / Twitter29 posts
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YouTube2 videos
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News2 articles
AI synopsis
What people are saying
Several discussions highlight the promising results, such as mentions of PVC suppression and increased ejection fraction, with phrases like 'exciting' and 'limited sample' indicating enthusiasm tempered by caution. The tone suggests a recognition of potential clinical significance, while also emphasizing the need for more extensive studies to confirm these initial findings.
Most discussions acknowledge the publication's findings, with some emphasizing the positive effects of class 1C antiarrhythmics on PVC suppression and ventricular function, indicating general consensus or support.
The discussions show high curiosity about the study, with many posts highlighting exciting or promising results, suggesting strong engagement from the audience interested in cardiac therapeutics.
Posts often reference specific outcomes like LVEF improvements and PVC suppression, and some mention the need for larger studies, demonstrating active participation and analysis of the research details.
While the discussion recognizes potential benefits, most posts imply that the findings could influence future research and clinical practice, but they also note the limited sample size, suggesting moderate perceived impact.
Abstract in brief
- PVCs are common in heart failure patients and can lead to worsened outcomes; class 1C antiarrhythmic drugs (AADs), while effective, have restricted use due to guidelines.
- This study evaluated the safety and effectiveness of class 1C AADs (specifically flecainide and propafenone) in patients with nonischemic cardiomyopathy (NICM) who have implantable cardioverter-defibrillators (ICDs).
- Results showed a significant reduction in PVC burden, improvement in left ventricular ejection fraction, and increased biventricular pacing percentage, with few safety concerns, suggesting class 1C AADs are beneficial for these patients, but more extensive research is necessary for definitive
Top posts
Most liked on X and BlueskyNEW EPISODE OF THE LEAD! [Ep. 66] A Discussion of Class 1C Antiarrhythmics for Premature Ventricular Complex Suppression in Nonischemic Cardiomyopathy With Implantable Cardioverter-Defibrillators
Exciting paper from Penn looking retrospectively (though small n) @ NICM pts w ICD on class Ic drugs for PVC suppression: ⬇️ PVCs ⬇️ sustained VT ⬆️ EF ⬆️ BiV pacing % https://t.co/kH4kwxQ8Cm
Class 1C antiarrhythmic drugs effectively suppressed PVCs in patients with NICM and ICDs, leading to increases in #LVEF and biventricular pacing percentage. In this limited sample, their use was safe. Larger studies are needed https://t.co/FDSv2nyRVt #JACCCEP via @JACCJournals https://t.co/NXSaoVqVmK
https://t.co/J7bMX3Swh8
RT @NikhilShahMD: Exciting paper from Penn looking retrospectively (though small n) @ NICM pts w ICD on class Ic drugs for PVC suppression:…
All mentions
Advances in Class 1C Antiarrhythmic Use for Heart Failure Patients
This week's podcast covers topics including Inclisiran updates, sodium channel blockers, and analytic flexibility in research. The study on class 1C antiarrhythmics shows they can reduce PVCs and improve heart function…
Advances in Cardiology Treatments and Genetic Insights April 2024
This week's cardiology update covers statins and diabetes, antiarrhythmic drugs in serious heart disease, and latest research on PVC suppression in patients with NICM and ICDs.
RT @HRSonline: NEW EPISODE OF THE LEAD! [Ep. 66] A Discussion of Class 1C Antiarrhythmics for Premature Ventricular Compl…
RT @HRSonline: NEW EPISODE OF THE LEAD! [Ep. 66] A Discussion of Class 1C Antiarrhythmics for Premature Ventricular Compl…
https://t.co/J7bMX3Swh8
RT @HRSonline: NEW EPISODE OF THE LEAD! [Ep. 66] A Discussion of Class 1C Antiarrhythmics for Premature Ventricular Compl…
RT @HRSonline: NEW EPISODE OF THE LEAD! [Ep. 66] A Discussion of Class 1C Antiarrhythmics for Premature Ventricular Compl…
RT @HRSonline: NEW EPISODE OF THE LEAD! [Ep. 66] A Discussion of Class 1C Antiarrhythmics for Premature Ventricular Compl…
RT @HRSonline: NEW EPISODE OF THE LEAD! [Ep. 66] A Discussion of Class 1C Antiarrhythmics for Premature Ventricular Compl…
RT @HRSonline: NEW EPISODE OF THE LEAD! [Ep. 66] A Discussion of Class 1C Antiarrhythmics for Premature Ventricular Compl…
RT @HRSonline: NEW EPISODE OF THE LEAD! [Ep. 66] A Discussion of Class 1C Antiarrhythmics for Premature Ventricular Compl…
NEW EPISODE OF THE LEAD! [Ep. 66] A Discussion of Class 1C Antiarrhythmics for Premature Ventricular Complex Suppression in Nonischemic Cardiomyopathy With Implantable Cardioverter-Defibrillators
Class 1C antiarrhythmic drugs effectively suppressed PVCs in patients with NICM and ICDs, leading to increases in #LVEF and biventricular pacing percentage. In this limited sample, their use was safe. Larger studies are needed https://t.co/FDSv2nyRVt #JACCCEP via @JACCJournals https://t.co/NXSaoVqVmK
RT @JACCJournals: Class 1C antiarrhythmic drugs effectively suppressed PVCs in patients with NICM and ICDs, leading to increases in #LVEF a…
RT @JACCJournals: Class 1C antiarrhythmic drugs effectively suppressed PVCs in patients with NICM and ICDs, leading to increases in #LVEF a…
RT @JACCJournals: Class 1C antiarrhythmic drugs effectively suppressed PVCs in patients with NICM and ICDs, leading to increases in #LVEF a…
RT @JACCJournals: Class 1C antiarrhythmic drugs effectively suppressed PVCs in patients with NICM and ICDs, leading to increases in #LVEF a…
RT @JACCJournals: Class 1C antiarrhythmic drugs effectively suppressed PVCs in patients with NICM and ICDs, leading to increases in #LVEF a…
RT @JACCJournals: Class 1C antiarrhythmic drugs effectively suppressed PVCs in patients with NICM and ICDs, leading to increases in #LVEF a…
RT @JACCJournals: Class 1C antiarrhythmic drugs effectively suppressed PVCs in patients with NICM and ICDs, leading to increases in #LVEF a…
RT @JACCJournals: Class 1C antiarrhythmic drugs effectively suppressed PVCs in patients with NICM and ICDs, leading to increases in #LVEF a…
RT @JACCJournals: Class 1C antiarrhythmic drugs effectively suppressed PVCs in patients with NICM and ICDs, leading to increases in #LVEF a…
RT @JACCJournals: Class 1C antiarrhythmic drugs effectively suppressed PVCs in patients with NICM and ICDs, leading to increases in #LVEF a…
RT @JACCJournals: Class 1C antiarrhythmic drugs effectively suppressed PVCs in patients with NICM and ICDs, leading to increases in #LVEF a…
RT @JACCJournals: Class 1C antiarrhythmic drugs effectively suppressed PVCs in patients with NICM and ICDs, leading to increases in #LVEF a…
RT @JACCJournals: Class 1C antiarrhythmic drugs effectively suppressed PVCs in patients with NICM and ICDs, leading to increases in #LVEF a…
Class 1C antiarrhythmic drugs effectively suppressed PVCs in patients with NICM and ICDs, leading to increases in #LVEF and biventricular pacing percentage. In this limited sample, their use was safe. Larger studies are needed https://t.co/fMZfHz6wMa #JACCCEP #EPeeps #epICD https://t.co/wrtChulnlA
RT @NikhilShahMD: Exciting paper from Penn looking retrospectively (though small n) @ NICM pts w ICD on class Ic drugs for PVC suppression:…
RT @NikhilShahMD: Exciting paper from Penn looking retrospectively (though small n) @ NICM pts w ICD on class Ic drugs for PVC suppression:…
Exciting paper from Penn looking retrospectively (though small n) @ NICM pts w ICD on class Ic drugs for PVC suppression: ⬇️ PVCs ⬇️ sustained VT ⬆️ EF ⬆️ BiV pacing % https://t.co/kH4kwxQ8Cm
Class 1C Antiarrhythmics for Premature Ventricular Complex Suppression in Nonischemic Cardiomyopathy With Implantable Cardioverter-Defibrillators https://t.co/ndirVMT8PU