SimuCell3D: three-dimensional simulation of tissue mechanics with cell polarization.

Steve Runser, Roman Vetter, Dagmar Iber

April 2024 Nat Comput Sci

Synopsis of Social media discussions

Discussions highlight the significance of the new simulation tool, with expressions like 'Can't wait to see it used!!' and mentions of its published status, indicating enthusiasm and recognition of its potential impact. The tone is positive and anticipatory, reflecting strong interest and belief in its importance for tissue mechanics research.

A
Agreement
 Moderate agreement

Most discussions express positive support and appreciation for the tool's development and potential applications.

I
Interest
 High level of interest

The overall tone shows high curiosity, especially with mentions of the source code release and anticipation for future use.

E
Engagement
 Moderate level of engagement

They reference specific features like cell polarization, tissue mechanics, and open science, indicating a moderate level of detailed engagement.

I
Impact
 Moderate level of impact

Participants see this simulation tool as potentially influential, evidenced by their excitement about its application and availability.

Social Mentions

YouTube

3 Videos

Bluesky

1 Posts

Facebook

2 Posts

Twitter

10 Posts

Metrics

Video Views

1,052

Total Likes

54

Extended Reach

20,290

Social Features

16

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

SimuCell3D: 3D Tissue Mechanics and Cell Polarization Simulation

SimuCell3D: 3D Tissue Mechanics and Cell Polarization Simulation

Computer simulation of cell proliferation in SimuCell3D, an open-source framework for modeling 3D cell mechanics with polarized cells. This tool enables exploration of tissue development and disease mechanisms by simulating large, complex tissue geometries and biomechanical interactions.

CoBi Group

January 17, 2025

723 views

3D Vesicle Growth Simulation with Lumen Using SimuCell3D

3D Vesicle Growth Simulation with Lumen Using SimuCell3D

Computer simulation of a growing spheroid vesicle with a lumen in SimuCell3D, an open-source framework for 3D cell mechanics with polarized cells, providing insights into tissue structure and development.

CoBi Group

January 17, 2025

288 views

DevoWorm 2024: 10 Years of 3D Modeling, Language Models, and Soft Materials Advances

DevoWorm 2024: 10 Years of 3D Modeling, Language Models, and Soft Materials Advances

Celebrating a decade of DevoWorm developments, including 3D tissue simulation, language models, and soft materials research, focusing on patterns, symmetries, and tissue mechanics insights.

DevoWorm

April 15, 2024

41 views

  • epithelial mechanics fan club
    @epimechfc.bsky.social (Bluesky)

    Runser, S., Vetter, R., & Iber, D. (2024). SimuCell3D: three-dimensional simulation of tissue mechanics with cell polarization. Nature computational science, 4(4), 299–309. #EpithelialMechanics buff.ly/TQGLwDX
    view full post

    June 6, 2025

    10

  • kato masaki
    @grizzly_41 (Twitter)

    RT @BioDecoded: SimuCell3D: three-dimensional simulation of tissue mechanics with cell polarization https://t.co/bjGZlvqzj7 #Bioinformatics
    view full post

    May 16, 2024

    1

  • BioDecoded
    @BioDecoded (Twitter)

    SimuCell3D: three-dimensional simulation of tissue mechanics with cell polarization https://t.co/bjGZlvqzj7 #Bioinformatics
    view full post

    May 15, 2024

    6

    1

  • Robin Journot
    @RobinJournot (Twitter)

    RT @DagmarIber: #SimuCell3D is now out in @NatComputSci https://t.co/yMPicxgA9R - Massive thx to the editor Fernando Chirigati @fchirigat…
    view full post

    May 15, 2024

    5

  • * Checks Notes, Shakes Head *
    @balicea1 (Twitter)

    RT @Orthogonal_Lab: The DevoWorm meeting (
    view full post

    April 15, 2024

    1

  • Orthogonal Research and Education Lab
    @Orthogonal_Lab (Twitter)

    The DevoWorm meeting (
    view full post

    April 15, 2024

    2

    1

  • Kevin Thurley
    @ThurleyLab (Twitter)

    RT @DagmarIber: #SimuCell3D is now out in @NatComputSci https://t.co/yMPicxgA9R - Massive thx to the editor Fernando Chirigati @fchirigat…
    view full post

    April 13, 2024

    5

  • Erika Tsingos
    @tisrenk (Twitter)

    RT @DagmarIber: #SimuCell3D is now out in @NatComputSci https://t.co/yMPicxgA9R - Massive thx to the editor Fernando Chirigati @fchirigat…
    view full post

    April 11, 2024

    5

  • Philippe Andrey
    @AndreyLab_fr (Twitter)

    RT @DagmarIber: #SimuCell3D is now out in @NatComputSci https://t.co/yMPicxgA9R - Massive thx to the editor Fernando Chirigati @fchirigat…
    view full post

    April 9, 2024

    5

  • Nature Computational Science
    @NatComputSci (Twitter)

    RT @DagmarIber: #SimuCell3D is now out in @NatComputSci https://t.co/yMPicxgA9R - Massive thx to the editor Fernando Chirigati @fchirigat…
    view full post

    April 9, 2024

    5

  • Dagmar Iber
    @DagmarIber (Twitter)

    #SimuCell3D is now out in @NatComputSci https://t.co/yMPicxgA9R - Massive thx to the editor Fernando Chirigati @fchirigati for handling our manuscript so well!! The source code is available free online: https://t.co/Npvhr8eF3l Can't wait to see it used!! #openscience
    view full post

    April 9, 2024

    22

    5

Abstract Synopsis

  • The 3D structure of cells is crucial for tissue function, and changes in this structure can occur during development and disease.
  • SimuCell3D is a new open-source program designed to efficiently simulate large, complex tissues in 3D while accounting for various factors like cell growth and mechanical differences.
  • This tool allows researchers to import real tissue geometries from images and explore how various biomechanical parameters influence cell shapes and organization in tissues like epithelia, enhancing our understanding of development and disease.