Environ Health Perspect April 2024 PMID 38598326

Tissue Distribution of Polystyrene or Mixed Polymer Microspheres and Metabolomic Analysis after Oral Exposure in Mice.

Marcus M Garcia, Aaron S Romero, Seth D Merkley, Jewel L Meyer-Hagen, Charles Forbes, Eliane El Hayek, David P Sciezka, Rachel Templeton, Jorge Gonzalez-Estrella, Yan Jin, Haiwei Gu, Angelica Benavidez, Russell P Hunter, Selita Lucas, Guy Herbert

Mentions

84
Peak: 29 in Apr 2024
across 4 sources since Apr 2024

Extended reach

754,218
potential audience

Total likes

970

Video views

83,903

Mentions per month

Apr 2024 – Feb 2025

Where it's discussed

  • News41 articles
  • X / Twitter38 posts
  • Blogs3 articles
  • YouTube2 videos

AI synopsis

What people are saying

Discussions extensively praise the research, emphasizing how microplastics travel through organs like the brain and liver, often describing the findings as eye-opening or impactful. The tone is scholarly yet engaged, with examples such as mentions of metabolic disruptions and microplastics' ability to infiltrate tissues, illustrating a collective recognition of the importance and urgency of addressing microplastic pollution's health effects.

AgreementStrong agreement

Most discussions highlight the significance and findings of the research, showing strong agreement on its importance.

InterestHigh interest

Posts demonstrate high interest by sharing details of the tissue distribution, metabolic impacts, and real-world implications.

EngagementHigh engagement

Several comments reference specific methodology, biological impacts, and collaborations, indicating deep engagement.

ImpactHigh impact

The widespread sharing, recognition of researchers, and emphasis on microplastics' health effects reflect a high perceived impact.

Abstract in brief

  • Global plastic use leads to significant environmental issues, with a large amount ending up in oceans and landfills, where it decomposes into microplastics (MPs) that pose health risks to both animals and humans.
  • The study investigates how polymer microspheres, specifically polystyrene and a mixture of different plastics, affect tissue metabolism and their ability to cross the gut barrier in mice.
  • Results showed that ingested microspheres were found in various organs, including the brain, liver, and kidneys, and caused metabolic changes in these tissues, highlighting the need to explore the health implications of mixed microplastics exposure.

Top posts

Most liked on X and Bluesky
Dr. Ilin Gilberto de la Torre M.
@IlindelatorreMD · X

Cómo los microplásticos escapan del intestino para inflirtrarse en el cerebro Distribución in vivo del tejido de poliestireno o microesferas de polímeros mixtos y análisis metabólico después de la exposición oral en ratones https://t.co/bU75jnAscG https://t.co/AaOj7S4Lhu

Apr 18, 2024 · 22 likes · 7 shares · 45,815 followers View post →
Eliseo Castillo
@eliseo_fc · X

Congratulations to current and past @UNMSOM_GI Castillo lab members as well as collaborators who helped on this paper. https://t.co/QQ5yVaNjfU we examine the biodistribution of #Microplastics and subsequent #Metabolomic changes in the gut, liver and brain.

Apr 10, 2024 · 12 likes · 1 share · 308 followers View post →
Environmental Health Perspectives
@EHPonline · X

MOST READ RESEARCH in April: In Vivo Tissue Distribution of Polystyrene or Mixed Polymer Microspheres and Metabolomic Analysis after Oral Exposure in Mice ➡️https://t.co/18or15Gd90  @eliseo_fc https://t.co/EApiJXksvN

May 2, 2024 · 6 likes · 1 share · 10,760 followers View post →
Environmental Health Perspectives
@EHPonline · X

NEW: Garcia et al. exposed mice to plastic microspheres and documented mobility within and between biological tissues, emphasizing the importance of understanding the metabolic impact of microplastic ingestion ➡️ https://t.co/lz7DwfUpSy @eliseo_fc https://t.co/SWawddeiBm

Apr 10, 2024 · 6 likes · 4 shares · 10,760 followers View post →
Environmental Health Perspectives
@EHPonline · X

MOST READ RESEARCH last week: In Vivo Tissue Distribution of Polystyrene or Mixed Polymer Microspheres and Metabolomic Analysis after Oral Exposure in Mice ➡️ https://t.co/sMQYwO0twZ @eliseo_fc https://t.co/G82LSrXiUu

Apr 22, 2024 · 3 likes · 1 share · 10,760 followers View post →
Neuroscience News
@NeuroscienceNew · X

“In Vivo Tissue Distribution of Polystyrene or Mixed Polymer Microspheres and Metabolomic Analysis after Oral Exposure in Mice” by Eliseo Castillo et al. Environmental Health Perspectives https://t.co/cev4ZZFMeU 3/3

Apr 15, 2024 · 2 likes · 1 share · 505,785 followers View post →

All mentions

The GUT CLUB
@club_gut · X

@_atanas_ @adem_onar @CurieuxExplorer @HealthyFellow @_MCRicardo_ @PalmGardenHC @dronita_de @DrSharadVats1 @_Sivasai @erlesen @Science_George @DrFerdowsi @AIZiadSaliba @Nwauka @Eli_Krumova @Devkota_HP "mice that ingested microspheres, we detected polystyrene microspheres in distant tissues including the brain, liver, and kidney. metabolic differences that occurred in the colon, liver, and brain,.dependent on concentration..type of microsphere exposure." https://t.co/Hq9zkHcLjW

Feb 5, 2025 · 1 like · 2,339 followers View post →
Paul Fowler
@GrumpybaldProf · X

In Vivo Tissue Distribution of Polystyrene or Mixed Polymer Microspheres and Metabolomic Analysis after Oral Exposure in Mice | Environmental Health Perspectives | Vol. 132, No. 4 https://t.co/pU7PAK97Wa

Jul 2, 2024 · 1,219 followers View post →
John Maki
@John_W_Maki · X

In Vivo Tissue Distribution of Polystyrene or Mixed Polymer Microspheres and Metabolomic Analysis after Oral Exposure in Mice | Environmental Health Perspectives | Vol. 132, No. 4 https://t.co/iJ4dXxqDXf

Jun 21, 2024 · 242 followers View post →
Environmental Health Perspectives
@EHPonline · X

MOST READ RESEARCH last week: In Vivo Tissue Distribution of Polystyrene or Mixed Polymer Microspheres and Metabolomic Analysis after Oral Exposure in Mice ➡️ https://t.co/3vrpwVSu9k https://t.co/ymKXFuARN4

Jun 10, 2024 · 2 likes · 10,760 followers View post →
Dr. Kim E. Barrett
@DrKimEBarrett · X

RT @UCDMouseBio: New mouse models research shows microplasics travel throughout accumulating in the brain, liver, and kidneys. These tiny…

Jun 3, 2024 · 1 share · 6,509 followers View post →
Mutant Mouse Resource & Research Centers
@MMRRC · X

New mouse models research shows microplasics travel throughout accumulating in the brain, liver, and kidneys. These tiny invaders may also disrupt metabolism. Source: https://t.co/6DX8H6wE5Q) https://t.co/YjiEFYcGls

Jun 3, 2024 · 2 likes · 409 followers View post →
UC Davis Mouse Biology Program
@UCDMouseBio · X

New mouse models research shows microplasics travel throughout accumulating in the brain, liver, and kidneys. These tiny invaders may also disrupt metabolism. Source: https://t.co/NG3SPg3E4w) https://t.co/ro8qJ0AuU5

Jun 3, 2024 · 2 likes · 1 share · 766 followers View post →
Eliseo Castillo
@eliseo_fc · X

RT @EHPonline: MOST READ RESEARCH in April: In Vivo Tissue Distribution of Polystyrene or Mixed Polymer Microspheres and Metabolomic Analys…

May 2, 2024 · 1 share · 308 followers View post →
Environmental Health Perspectives
@EHPonline · X

MOST READ RESEARCH in April: In Vivo Tissue Distribution of Polystyrene or Mixed Polymer Microspheres and Metabolomic Analysis after Oral Exposure in Mice ➡️https://t.co/18or15Gd90  @eliseo_fc https://t.co/EApiJXksvN

May 2, 2024 · 6 likes · 1 share · 10,760 followers View post →
Eliseo Castillo
@eliseo_fc · X

RT @EHPonline: #ICYMI...NEW RESEARCH: In Vivo Tissue Distribution of Polystyrene or Mixed Polymer Microspheres and Metabolomic Analysis aft…

May 1, 2024 · 1 share · 308 followers View post →
Environmental Health Perspectives
@EHPonline · X

#ICYMI...NEW RESEARCH: In Vivo Tissue Distribution of Polystyrene or Mixed Polymer Microspheres and Metabolomic Analysis after Oral Exposure in Mice ➡️ https://t.co/cTS5oz2Dxk @eliseo_fc

May 1, 2024 · 2 likes · 1 share · 10,760 followers View post →
James Moore
@jamesdmoore614 · X

#Beach clean up. Found so much #plastic https://t.co/YNWldndvFs https://t.co/Duci1XZVB0

Apr 27, 2024 · 1,440 followers View post →
Eliseo Castillo
@eliseo_fc · X

RT @EHPonline: MOST READ RESEARCH last week: In Vivo Tissue Distribution of Polystyrene or Mixed Polymer Microspheres and Metabolomic Analy…

Apr 22, 2024 · 1 share · 308 followers View post →
Environmental Health Perspectives
@EHPonline · X

MOST READ RESEARCH last week: In Vivo Tissue Distribution of Polystyrene or Mixed Polymer Microspheres and Metabolomic Analysis after Oral Exposure in Mice ➡️ https://t.co/sMQYwO0twZ @eliseo_fc https://t.co/G82LSrXiUu

Apr 22, 2024 · 3 likes · 1 share · 10,760 followers View post →
benishii
@benishii_ · X

Microplastics in alle organen tot brein... https://t.co/XBiy1Y5beX

Apr 21, 2024 · 2,601 followers View post →
Georges GASSITA
@Georges_GASSITA · X

https://t.co/t1AIxHw2ZJ

Apr 19, 2024 · 649 followers View post →
maria teresa vieira
@maritevi · X

RT @IlindelatorreMD: Cómo los microplásticos escapan del intestino para inflirtrarse en el cerebro Distribución in vivo del tejido de poli…

Apr 18, 2024 · 7 shares · 1,367 followers View post →
Dr. Burnout
@Dr_Kratos_ · X

RT @IlindelatorreMD: Cómo los microplásticos escapan del intestino para inflirtrarse en el cerebro Distribución in vivo del tejido de poli…

Apr 18, 2024 · 7 shares · 68 followers View post →
Lulu
@imlulual · X

RT @IlindelatorreMD: Cómo los microplásticos escapan del intestino para inflirtrarse en el cerebro Distribución in vivo del tejido de poli…

Apr 18, 2024 · 7 shares · 368 followers View post →
Johana Sefair
@Jsefair1 · X

RT @IlindelatorreMD: Cómo los microplásticos escapan del intestino para inflirtrarse en el cerebro Distribución in vivo del tejido de poli…

Apr 18, 2024 · 7 shares · 42 followers View post →
yamile escobar
@DoctoraYescobar · X

RT @IlindelatorreMD: Cómo los microplásticos escapan del intestino para inflirtrarse en el cerebro Distribución in vivo del tejido de poli…

Apr 18, 2024 · 7 shares · 1,169 followers View post →
Galia Ortiz
@o_galia · X

RT @IlindelatorreMD: Cómo los microplásticos escapan del intestino para inflirtrarse en el cerebro Distribución in vivo del tejido de poli…

Apr 18, 2024 · 7 shares · 257 followers View post →
Dr. Ilin Gilberto de la Torre M.
@IlindelatorreMD · X

Cómo los microplásticos escapan del intestino para inflirtrarse en el cerebro Distribución in vivo del tejido de poliestireno o microesferas de polímeros mixtos y análisis metabólico después de la exposición oral en ratones https://t.co/bU75jnAscG https://t.co/AaOj7S4Lhu

Apr 18, 2024 · 22 likes · 7 shares · 45,815 followers View post →
Chuma.
@ChumaOps · X

Your Takeaway: Stay informed. Stay healthy. And maybe, it’s time to cut down on that plastic use.

Apr 18, 2024 · 142 followers View post →
Michael Bertakis
@MICHAELBERTAKIS · X

Μικροπλαστικά: Ανιχνεύθηκαν στον εγκέφαλο και στις πέτρες της χολής https://t.co/xzVVL5Z5KF

Apr 18, 2024 · 302 followers View post →
ULDARICO RAMIREZ PER
@uldaricorape · X

Microplásticos viajan del Intestino al Cerebro. Este tema no es prioridad en Colombia. Nos toca en nuestras familias sacar la Plata $$$$ para los tratamientos y lo mas complicado, todos los males los tendremos viejos. https://t.co/98cyAWQyXR https://t.co/f8eopOyVOf https://t.co/jqe0Z5M4IH

Apr 16, 2024 · 1 like · 932 followers View post →
Ismail AlMadany
@ProfIsAlMadany · X

دراسة مخبرية نُشرت في مجلة(Environmental Health Perspectives)(10أبريل)،حيث تم تعريض الفئران لجسيمات البلاستيك المجهرية،وهذه الجسيمات انتقلت إلى الجهاز الهضمي ومنها إلى أنسجة الكلية والكبد والمخ،مما يؤكد بأن هذه الجسيمات أيضاً موجودة في خلايا أعضائنا!!! https://t.co/akNzEHnIXL

Apr 16, 2024 · 1 like · 4,157 followers View post →
Professor Erwin Loh
@erwinloh · X

#Microplastics make their way from the #gut to other organs: study found that microplastics are having a significant impact on our #digestive pathways, making their way from the gut and into the tissues of the #kidney, #liver and #brain. https://t.co/jvDLXZDKHB https://t.co/qs2rkluyY5

Apr 16, 2024 · 1 like · 9,478 followers View post →
中武 壮以知
@soichinakatake · X

マイクロプラスチックは、腸関門を越えてリンパ循環や全身循環に入り、肺、肝臓、腎臓、脳などの組織に蓄積する」 In Vivo Tissue Distribution of Polystyrene or Mixed Polymer Microspheres and Metabolomic Analysis after Oral Exposure in Mice https://t.co/vNUqu94663

Apr 16, 2024 · 137 followers View post →
こだまゆうじ
@douwaenn1 · X

RT @norionakatsuji: 元論文→ Reference: Garcia MM, Romero AS, Merkley SD, et al. In vivo tissue distribution of polystyrene or mixed polymer mi…

Apr 15, 2024 · 1 share · 792 followers View post →
Norio Nakatsuji
@norionakatsuji · X

元論文→ Reference: Garcia MM, Romero AS, Merkley SD, et al. In vivo tissue distribution of polystyrene or mixed polymer microspheres and metabolomic analysis after oral exposure in mice. Environ Health Perspect. 2024;132(4):047005. doi: 10.1289/EHP13435 https://t.co/RPrGUCVLMr

Apr 15, 2024 · 1 like · 1 share · 15,696 followers View post →
deziner
@adeziner1984 · X

RT @NeuroscienceNew: “In Vivo Tissue Distribution of Polystyrene or Mixed Polymer Microspheres and Metabolomic Analysis after Oral Exposure…

Apr 15, 2024 · 1 share · 656 followers View post →
Neuroscience News
@NeuroscienceNew · X

“In Vivo Tissue Distribution of Polystyrene or Mixed Polymer Microspheres and Metabolomic Analysis after Oral Exposure in Mice” by Eliseo Castillo et al. Environmental Health Perspectives https://t.co/cev4ZZFMeU 3/3

Apr 15, 2024 · 2 likes · 1 share · 505,785 followers View post →
UNM Gastroenterology & Hepatology
@UNMSOM_GI · X

RT @eliseo_fc: Congratulations to current and past @UNMSOM_GI Castillo lab members as well as collaborators who helped on this paper. https…

Apr 10, 2024 · 1 share · 390 followers View post →
Environmental Health Perspectives
@EHPonline · X

NEW RESEARCH: In Vivo Tissue Distribution of Polystyrene or Mixed Polymer Microspheres and Metabolomic Analysis after Oral Exposure in Mice ➡️ https://t.co/YrBVYs3xUL @eliseo_fc

Apr 10, 2024 · 2 likes · 1 share · 10,760 followers View post →
UofL's Christina Lee Brown Envirome Institute
@UofLEnvirome · X

RT @EHPonline: NEW: Garcia et al. exposed mice to plastic microspheres and documented mobility within and between biological tissues, empha…

Apr 10, 2024 · 4 shares · 653 followers View post →
Eliseo Castillo
@eliseo_fc · X

Congratulations to current and past @UNMSOM_GI Castillo lab members as well as collaborators who helped on this paper. https://t.co/QQ5yVaNjfU we examine the biodistribution of #Microplastics and subsequent #Metabolomic changes in the gut, liver and brain.

Apr 10, 2024 · 12 likes · 1 share · 308 followers View post →
Environmental Health Perspectives
@EHPonline · X

NEW: Garcia et al. exposed mice to plastic microspheres and documented mobility within and between biological tissues, emphasizing the importance of understanding the metabolic impact of microplastic ingestion ➡️ https://t.co/lz7DwfUpSy @eliseo_fc https://t.co/SWawddeiBm

Apr 10, 2024 · 6 likes · 4 shares · 10,760 followers View post →