Endoscopy September 2024 PMID 38599622

Over-the-scope clip as first-line treatment of peptic ulcer bleeding: a multicenter randomized controlled trial (TOP Study).

Paola Soriani, Paolo Biancheri, Giuliano Francesco Bonura, Tommaso Gabbani, Enrique Rodriguez de Santiago, Lorenzo Dioscoridi, Gianluca Andrisani, Carmelo Luigiano, Simona Deiana, Joachim Rainer, Mariagrazia Del Buono, Rocco Amendolara, Massimiliano Marino, Cesare Hassan, Alessandro Repici

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Mentions

23
Peak: 20 in Sep 2024
across 3 sources since Aug 2024

Extended reach

84,648
potential audience

Total likes

94

Video views

164

Mentions per month

Aug 2024 – Sep 2024

Where it's discussed

  • X / Twitter20 posts
  • Facebook2 posts
  • YouTube1 videos

AI synopsis

What people are saying

Participants discuss the study's findings, noting that OTS clips significantly lower rebleeding rates (16% vs. 39%) and improve initial hemostasis success, with tone emphasizing their potential to transform treatment strategies. The use of phrases like 'superior efficacy' and references to the study as an 'editor's choice' reflect respect for the research's impact.

AgreementModerate agreement

Most discussions acknowledge the study’s positive results supporting OTS clips due to their higher efficacy in preventing rebleeding.

InterestModerate interest

Posts show moderate curiosity, highlighting the clinical benefits and potential changes in treatment protocols.

EngagementModerate engagement

Comments reference specific results, such as rebleeding rates and success rates, indicating a reasonable depth of analysis.

ImpactModerate impact

The discussions suggest that the findings could influence clinical practice, emphasizing the importance of adopting OTS clips as a first-line approach.

Abstract in brief

  • A multicenter randomized controlled trial compared the effectiveness of Overthescope (OTS) clips versus through-the-scope (TTS) clips as first-line treatments for peptic ulcer bleeding, showing that OTS clips had a lower 30-day rebleeding rate and higher success in initial hemostasis and overall clinical success.
  • Results indicated that 16% of patients treated with OTS clips experienced rebleeding within 30 days compared to 39% with TTS clips, with OTS clips also achieving higher rates of successful initial hemostasis (98.4% vs. 78.4%) and overall clinical success (96.7% vs. 74.5%).
  • The study concludes that while both clip types are effective, OTS clips demonstrate superior efficacy as the first-line endoscopic treatment for acute peptic ulcer bleeding.

Top posts

Most liked on X and Bluesky
Lumír Kunovský
@LumirKunovsky · X

Sep 14, 2024 · 54 likes · 18 shares · 2,713 followers View post →
Endoscopy Journal
@endoscopyjrnl · X

Editor's Choice: Multicenter RCT on OTS clip as first-line treatment for peptic ulcer bleeding Find the article at: https://t.co/yKp4S1RZy8 Paola Soriani et al. https://t.co/P6JihGNrC4

Sep 11, 2024 · 18 likes · 5 shares · 11,553 followers View post →
Klaus Mönkemüller, MD, PhD
@KMonkemuller · X

✅ Our strategy

Sep 21, 2024 · 14 likes · 4 shares · 14,329 followers View post →
Endoscopy Journal
@endoscopyjrnl · X

#AuthorCommentary: P. Soriani, M. Manno, G. F. Bonura & P. Biancheri on "Over-the-scope clip as first-line treatment of peptic ulcer bleeding: a multicenter randomized controlled trial (TOP Study)" Watch the video here: https://t.co/MFrc2w6LAf

Sep 13, 2024 · 6 likes · 3 shares · 11,535 followers View post →
Nutrition Support Team
@NSTSteppingHill · X

Over-the-scope clip as first-line treatment of peptic ulcer bleeding: a multicenter randomized controlled trial (TO… https://t.co/WBvmWkNZwn

Sep 22, 2024 · 1 like · 604 followers View post →
Steven Bollipo
@stevenbollipo · X

RT @endoscopyjrnl: #AuthorCommentary: P. Soriani, M. Manno, G. F. Bonura & P. Biancheri on "Over-the-scope clip as first-line treatme…

Sep 14, 2024 · 3 shares · 16,693 followers View post →

All mentions

Prof. Nasser Alzerwi
@NAlzerwi · X

RT @KMonkemuller: ✅ Our strategy

Sep 22, 2024 · 4 shares · 1,735 followers View post →
Nutrition Support Team
@NSTSteppingHill · X

Over-the-scope clip as first-line treatment of peptic ulcer bleeding: a multicenter randomized controlled trial (TO… https://t.co/WBvmWkNZwn

Sep 22, 2024 · 1 like · 604 followers View post →
Ary Rodríguez
@Ary_Rodriguez_ · X

RT @KMonkemuller: ✅ Our strategy

Sep 22, 2024 · 4 shares · 444 followers View post →
Adriana B
@Adribottero · X

RT @KMonkemuller: ✅ Our strategy

Sep 22, 2024 · 4 shares · 727 followers View post →
Laura Lucaciu
@lauraa_lexandra · X

RT @KMonkemuller: ✅ Our strategy

Sep 21, 2024 · 4 shares · 774 followers View post →
Klaus Mönkemüller, MD, PhD
@KMonkemuller · X

✅ Our strategy

Sep 21, 2024 · 14 likes · 4 shares · 14,329 followers View post →
Muaz Moosa
@muazmoosa · X

RT @endoscopyjrnl: Editor's Choice: Multicenter RCT on OTS clip as first-line treatment for peptic ulcer bleeding Find the article at: htt…

Sep 15, 2024 · 5 shares · 175 followers View post →
Jorge Luis Rodríguez .
@JL____Rodriguez · X

RT @LumirKunovsky:

Sep 14, 2024 · 18 shares · 1,351 followers View post →
Liudmyla Pererva
@LiudmylaPererva · X

RT @LumirKunovsky:

Sep 14, 2024 · 18 shares · 330 followers View post →
JOSFER
@JOSFER2011 · X

RT @LumirKunovsky:

Sep 14, 2024 · 18 shares · 875 followers View post →
Dr Celestino Gutiérrez González MD
@CelestinoGutirr · X

RT @LumirKunovsky:

Sep 14, 2024 · 18 shares · 11,323 followers View post →
Lumír Kunovský
@LumirKunovsky · X

Sep 14, 2024 · 54 likes · 18 shares · 2,713 followers View post →
Steven Bollipo
@stevenbollipo · X

RT @endoscopyjrnl: #AuthorCommentary: P. Soriani, M. Manno, G. F. Bonura & P. Biancheri on "Over-the-scope clip as first-line treatme…

Sep 14, 2024 · 3 shares · 16,693 followers View post →
Adriana B
@Adribottero · X

RT @endoscopyjrnl: #AuthorCommentary: P. Soriani, M. Manno, G. F. Bonura & P. Biancheri on "Over-the-scope clip as first-line treatme…

Sep 13, 2024 · 3 shares · 726 followers View post →
Endoscopy Journal
@endoscopyjrnl · X

#AuthorCommentary: P. Soriani, M. Manno, G. F. Bonura & P. Biancheri on "Over-the-scope clip as first-line treatment of peptic ulcer bleeding: a multicenter randomized controlled trial (TOP Study)" Watch the video here: https://t.co/MFrc2w6LAf

Sep 13, 2024 · 6 likes · 3 shares · 11,535 followers View post →
Passisd Laoveeravat
@passisd · X

RT @endoscopyjrnl: Editor's Choice: Multicenter RCT on OTS clip as first-line treatment for peptic ulcer bleeding Find the article at: htt…

Sep 13, 2024 · 5 shares · 377 followers View post →
Adriana B
@Adribottero · X

RT @endoscopyjrnl: Editor's Choice: Multicenter RCT on OTS clip as first-line treatment for peptic ulcer bleeding Find the article at: htt…

Sep 12, 2024 · 5 shares · 727 followers View post →
Anjum Gardezi MD
@SyedGerdezi · X

RT @endoscopyjrnl: Editor's Choice: Multicenter RCT on OTS clip as first-line treatment for peptic ulcer bleeding Find the article at: htt…

Sep 11, 2024 · 5 shares · 6,981 followers View post →
Yuri Gorelik
@GorelikYuri · X

OTSC set to be 1st line treatment for bleeding gastroduodenal ulcers https://t.co/FXp1Luz1Fc

Sep 11, 2024 · 225 followers View post →
Endoscopy Journal
@endoscopyjrnl · X

Editor's Choice: Multicenter RCT on OTS clip as first-line treatment for peptic ulcer bleeding Find the article at: https://t.co/yKp4S1RZy8 Paola Soriani et al. https://t.co/P6JihGNrC4

Sep 11, 2024 · 18 likes · 5 shares · 11,553 followers View post →