Aging Cell August 2024 PMID 38725282

Aging amplifies a gut microbiota immunogenic signature linked to heightened inflammation.

Maria Elisa Caetano-Silva, Akriti Shrestha, Audrey F Duff, Danica Kontic, Patricia C Brewster, Mikaela C Kasperek, Chia-Hao Lin, Derek A Wainwright, Diego Hernandez-Saavedra, Jeffrey A Woods, Michael T Bailey, Thomas W Buford, Jacob M Allen

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Mentions

157

Peak: 86 in May 2024

across 7 sources since Mar 2024

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Total likes

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Video views

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Mar 2024 – Sep 2024

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AI synopsis

What people are saying

Many discussions reference the core idea that aging exacerbates gut microbiota changes leading to elevated inflammation, using phrases like 'the gut microbiota plays an active role' and 'critical factors in mediating chronic inflammatory diseases.' The choice of words and tone conveys both seriousness and urgency about the relationship between aging and gut health, with some posts openly speculating on future research directions and impacts on health.

AgreementModerate agreement

The majority of discussions reflect a favorable view towards the publication's findings, with users expressing concurrence on the link between aging and gut microbiota-related inflammation.

InterestHigh interest

There is a high level of curiosity as many discussions revolve around the implications of the findings, highlighting the relevance of gut health in aging.

EngagementModerate engagement

Although many posts contain repeating phrases, some users delve deeper by discussing the mechanisms of inflammation and the significance of gut microbiota.

ImpactHigh impact

Several users convey that the findings are significant, emphasizing the role of gut microbiota in chronic inflammation and potential age-related diseases.

Abstract in brief

Aging is linked to low-grade inflammation that raises disease risk, possibly driven by changes in gut microbiota as we age.
Research on aged mice shows that alterations in gut bacteria lead to increased immune activation and inflammation markers, specifically through toll-like receptor 4 (TLR4).
The gut microbiota of older mice also responds differently to antibiotics, indicating that these age-related microbial changes contribute to chronic inflammation and may play a significant role in age-related diseases.

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@mayogisense · X

RT @Madam_Mito: Aging amplifies a gut microbiota immunogenic signature linked to heightened inflammation https://t.co/mXmQtgA41R

May 11, 2024 · 44 shares · 572 followers View post →

P123

@P1231032850 · X

RT @Madam_Mito: Aging amplifies a gut microbiota immunogenic signature linked to heightened inflammation https://t.co/mXmQtgA41R

May 11, 2024 · 44 shares · 3,219 followers View post →

AngryPhDstudent❗️❗️❗️

@ONNESHA092 · X

RT @Madam_Mito: Aging amplifies a gut microbiota immunogenic signature linked to heightened inflammation https://t.co/mXmQtgA41R

May 11, 2024 · 44 shares · 183 followers View post →

Pere Joan Sala

@Fradbius · X

L'envelliment amplifica una signatura immunogènica de la microbiota intestinal relacionada amb una inflamació augmentada. https://t.co/w5TFQy7o7E

May 11, 2024 · 248 followers View post →

Dr. Manos C. Vlasiou MRes, PhD, MRSC, CChem

@CVlasiou · X

RT @Madam_Mito: Aging amplifies a gut microbiota immunogenic signature linked to heightened inflammation https://t.co/mXmQtgA41R

May 11, 2024 · 44 shares · 752 followers View post →

Madam Mitochondria

@Madam_Mito · X

Aging amplifies a gut microbiota immunogenic signature linked to heightened inflammation https://t.co/mXmQtgA41R

May 11, 2024 · 124 likes · 44 shares · 10,514 followers View post →

Matías Monsalves-Álvarez

@profemonsalves · X

RT @Madam_Mito: #Aging amplifies a gut microbiota immunogenic signature linked to heightened #inflammation https://t.co/JmaXoQS8Ub @czisci…

Apr 23, 2024 · 8 shares · 1,509 followers View post →

Andreea Nitescu RD MSc

@AndreeaNRD · X

RT @Madam_Mito: #Aging amplifies a gut microbiota immunogenic signature linked to heightened #inflammation https://t.co/JmaXoQS8Ub @czisci…

Apr 23, 2024 · 8 shares · 1,284 followers View post →

Ryan Tidwell

@RyanTidwellPHC · X

RT @Madam_Mito: #Aging amplifies a gut microbiota immunogenic signature linked to heightened #inflammation https://t.co/JmaXoQS8Ub @czisci…

Apr 23, 2024 · 8 shares · 243 followers View post →

Madam Mitochondria

@Madam_Mito · X

RT @Madam_Mito: #Aging amplifies a gut microbiota immunogenic signature linked to heightened #inflammation https://t.co/JmaXoQS8Ub @czisci…

Apr 23, 2024 · 8 shares · 10,514 followers View post →

Manoj Mayogi Mishra

@mayogisense · X

RT @Madam_Mito: #Aging amplifies a gut microbiota immunogenic signature linked to heightened #inflammation https://t.co/JmaXoQS8Ub @czisci…

Mar 29, 2024 · 8 shares · 572 followers View post →

Hao Yin

@HaoYin20 · X

RT @Madam_Mito: #Aging amplifies a gut microbiota immunogenic signature linked to heightened #inflammation https://t.co/JmaXoQS8Ub @czisci…

Mar 29, 2024 · 8 shares · 12,294 followers View post →

Anirban Maitra

@Aiims1742 · X

RT @Madam_Mito: #Aging amplifies a gut microbiota immunogenic signature linked to heightened #inflammation https://t.co/JmaXoQS8Ub @czisci…

Mar 28, 2024 · 8 shares · 31,365 followers View post →

CHSeaton

@COSseaton · X

RT @Madam_Mito: #Aging amplifies a gut microbiota immunogenic signature linked to heightened #inflammation https://t.co/JmaXoQS8Ub @czisci…

Mar 28, 2024 · 8 shares · 5,934 followers View post →

Madam Mitochondria

@Madam_Mito · X

#Aging amplifies a gut microbiota immunogenic signature linked to heightened #inflammation https://t.co/JmaXoQS8Ub @cziscience

Mar 28, 2024 · 30 likes · 8 shares · 10,514 followers View post →

Tautaton

@tautaton · X

Mar 28, 2024 · 92 followers View post →

Olga Payar

@Olgapaval · X

RT @biorxiv_immuno: Aging amplifies a gut microbiota immunogenic signature linked to heightened inflammation https://t.co/dIMJPQVVz3 #bior…

Mar 27, 2024 · 1 share · 88 followers View post →

bioRxiv Immunology

@biorxiv-immuno.bsky.social · Bluesky

Aging amplifies a gut microbiota immunogenic signature linked to heightened inflammation https://www.biorxiv.org/content/10.1101/2024.03.22.586320v1

Mar 27, 2024 View post →

bioRxivpreprint

@biorxivpreprint.bsky.social · Bluesky

Aging amplifies a gut microbiota immunogenic signature linked to heightened inflammation https://www.biorxiv.org/content/10.1101/2024.03.22.586320v1

Mar 27, 2024 View post →

bioRxiv Immunology

@biorxiv_immuno · X

Aging amplifies a gut microbiota immunogenic signature linked to heightened inflammation https://t.co/dIMJPQVVz3 #biorxiv_immuno

Mar 27, 2024 · 4 likes · 1 share · 10,647 followers View post →

Aging amplifies a gut microbiota immunogenic signature linked to heightened inflammation.

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The Impact of Gut Microbiome on Aging and Inflammation

Impact of Aging on Gut Microbiome and Inflammation Levels

Ep. 71 - Do Bacteria Make Us Age