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N Engl J Med January 1985 PMID 3880867

High-dose vitamin C versus placebo in the treatment of patients with advanced cancer who have had no prior chemotherapy. A randomized double-blind comparison.

C G Moertel, T R Fleming, E T Creagan, J Rubin, M J O'Connell, M M Ames

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Mentions

26
Peak: 3 in May 2023
across 4 sources since Nov 2015

Extended reach

105,583
potential audience

Total likes

1,901

Video views

41,939

Mentions per month

Nov 2015 – Dec 2025

Where it's discussed

  • X / Twitter10 posts
  • Facebook7 posts
  • News7 articles
  • YouTube2 videos

AI synopsis

What people are saying

Many discussions focus on criticizing the study's methodology, citing prior limited animal or small case series evidence, and dismissing the trial's conclusions with statements like 'it’s worthless for now' or referencing failed replication attempts, which demonstrates a predominantly skeptical and dismissive attitude rather than curiosity or deep engagement.

AgreementStrong disagreement

Most discussions reject or dismiss the study, emphasizing its limitations and previous contradictory findings.

InterestLow interest

The tone indicates low curiosity or relevance, with users dismissing the trial as inconclusive or irrelevant.

EngagementLow engagement

Comments show superficial engagement, mainly dismissive remarks rather than in-depth analysis.

ImpactLow impact

The discussions suggest minimal impact, as users generally see the findings as predictable or already established.

Abstract in brief

  • The study involved 100 advanced colorectal cancer patients who had not received prior chemotherapy, and they were randomly assigned to receive either high-dose vitamin C or a placebo in a double-blind setup.
  • Results showed that high-dose vitamin C did not improve time to disease progression or patient survival compared to placebo, and no objective tumor improvements were observed.
  • The conclusion is that high-dose vitamin C is not effective as a treatment for advanced cancer, regardless of previous chemotherapy history.]
Read the full abstract

Top posts

Most liked on X and Bluesky
L ❤ V E
@drkohilathas · X

However, later publications did not show high-dose vitamin C therapy (HAAT) to benefit patients with advanced cancer. https://t.co/QGwyQaWHBa

May 2, 2023 · 21 likes · 1 share · 47,826 followers View post →
Jeremy Jones
@Jcj84Jeremy · X

@jgong15 @MayCho_MD @DrHendifar @mgfakih @marklewismd @guildsman @DrR_DUNNE @gabe_a_brooks @KristenCiombor @GIcancerDoc https://t.co/7ajIy1PWD8 Follow up trial. Also negative.

Nov 19, 2024 · 6 likes · 3 shares · 1,083 followers View post →
Tanios Bekaii-Saab, MD
@GIcancerDoc · X

RT @Jcj84Jeremy: @jgong15 @MayCho_MD @DrHendifar @mgfakih @marklewismd @guildsman @DrR_DUNNE @gabe_a_brooks @KristenCiombor @GIcancerDoc ht…

Nov 19, 2024 · 3 shares · 6,335 followers View post →
Joshua Plinge
@JoshuaPlinge · X

@TheSens1990 @GrumpybaldProf @stopvaccinating Do you mean this?: https://t.co/Vm0RGV00lh 10g would not be expected to have much effect on cancer, if any. Surprisingly Cameron did see a beneficial effect using only 10g IV. Someone failed to replicate this using 10g orally. Not a surprise. https://t.co/nn9qNJ3aQs

May 20, 2024 · 3,304 followers View post →
Ricardo Carvalho
@rcarvalhoonco · X

RT @Jcj84Jeremy: @jgong15 @MayCho_MD @DrHendifar @mgfakih @marklewismd @guildsman @DrR_DUNNE @gabe_a_brooks @KristenCiombor @GIcancerDoc ht…

Nov 19, 2024 · 3 shares · 2,274 followers View post →
Deepak Singh https://www.ijrh.org/ |
@homeopathy2010 · X

RT @drkohilathas: However, later publications did not show high-dose vitamin C therapy (HAAT) to benefit patients with advanced cancer. h…

May 2, 2023 · 1 share · 2,168 followers View post →

All mentions

Mishaa ☢️
@Sir_Mishaa · X

@mbjade7 @Evidencebbh @clarisselecter1 C'est parfait, a quasi-totalité des preuves repose sur des modèles animaux ou des séries de cas (phase I/II) très limitées (n < 50) Pas de test sur les humains, ça ne vaut absolument rien pour l'instant. Pour la vitamine C, test en double aveugle => https://t.co/W0Rpfkbuf1

Jun 24, 2025 · 113 followers View post →
Ricardo Carvalho
@rcarvalhoonco · X

RT @Jcj84Jeremy: @jgong15 @MayCho_MD @DrHendifar @mgfakih @marklewismd @guildsman @DrR_DUNNE @gabe_a_brooks @KristenCiombor @GIcancerDoc ht…

Nov 19, 2024 · 3 shares · 2,274 followers View post →
Tanios Bekaii-Saab, MD
@GIcancerDoc · X

RT @Jcj84Jeremy: @jgong15 @MayCho_MD @DrHendifar @mgfakih @marklewismd @guildsman @DrR_DUNNE @gabe_a_brooks @KristenCiombor @GIcancerDoc ht…

Nov 19, 2024 · 3 shares · 6,335 followers View post →
Jeremy Jones
@Jcj84Jeremy · X

@jgong15 @MayCho_MD @DrHendifar @mgfakih @marklewismd @guildsman @DrR_DUNNE @gabe_a_brooks @KristenCiombor @GIcancerDoc https://t.co/7ajIy1PWD8 Follow up trial. Also negative.

Nov 19, 2024 · 6 likes · 3 shares · 1,083 followers View post →
Joshua Plinge
@JoshuaPlinge · X

@TheSens1990 @GrumpybaldProf @stopvaccinating Do you mean this?: https://t.co/Vm0RGV00lh 10g would not be expected to have much effect on cancer, if any. Surprisingly Cameron did see a beneficial effect using only 10g IV. Someone failed to replicate this using 10g orally. Not a surprise. https://t.co/nn9qNJ3aQs

May 20, 2024 · 3,304 followers View post →
Super Dad
@TheSens1990 · X

@GrumpybaldProf @JoshuaPlinge @stopvaccinating Don't bother with this guy - here is 10 grams of Vitamin C - https://t.co/cYFYFcXGzp - no effect vs a sugar pill. He wanst you to have 150 grams of a vitamin. He's a moron

May 20, 2024 · 35 followers View post →
Lancillotto
@Lancillotto810 · X

RT @drkohilathas: However, later publications did not show high-dose vitamin C therapy (HAAT) to benefit patients with advanced cancer. h…

May 3, 2023 · 1 share · 255 followers View post →
Deepak Singh https://www.ijrh.org/ |
@homeopathy2010 · X

RT @drkohilathas: However, later publications did not show high-dose vitamin C therapy (HAAT) to benefit patients with advanced cancer. h…

May 2, 2023 · 1 share · 2,168 followers View post →
L ❤ V E
@drkohilathas · X

However, later publications did not show high-dose vitamin C therapy (HAAT) to benefit patients with advanced cancer. https://t.co/QGwyQaWHBa

May 2, 2023 · 21 likes · 1 share · 47,826 followers View post →
TKY1017
@Hematologist101 · X

@kubo3025 https://t.co/SfXUQ7IJjn 1985年の記事ですね。ビタミンCでがんに効果がないことは周知ですよ。

Nov 14, 2019 · 88 followers View post →
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