PubHawk
Biotechnol Bioeng September 2024 PMID 38837221

Combining descriptive and predictive modeling to systematically design depth filtration-based harvest processes for biologics.

Peter Liu, Michael Hartmann, Ajay Shankaran, Hong Li, John Welsh

Full text PDF Download social card

Mentions

11
Peak: 3 in Nov 2025
across 4 sources since Nov 2025

Extended reach

364
potential audience

Total likes

1

Video views

198

Mentions per month

Nov 2025

All 3 dated mentions so far are from Nov 2025.

Where it's discussed

  • Facebook4 posts
  • News4 articles
  • YouTube2 videos
  • X / Twitter1 posts

AI synopsis

What people are saying

We're still gathering social media discussions on this article. A synopsis appears once there are enough posts to summarize.

AgreementNeither agree nor disagree
InterestNeutral interest
EngagementNeutral engagement
ImpactNeutral impact

Abstract in brief

  • The article discusses how increased cell debris in biologic harvest processes has made traditional depth filtration less effective, causing a need for more robust, predictive tools to improve process development.
  • Historically, process development relied on resource-heavy screening and semiempirical models to understand filter fouling, but these methods are limited in guiding product development due to their descriptive nature.
  • To overcome these limitations, a hybrid modeling approach was developed that combines machine learning (partial least squares regression) with mechanistic fouling models, enabling better prediction and interpretation of filter performance based on historical process data.]
Read the full abstract

Top posts

Most liked on X and Bluesky
CHO Cell Papers
@CHOculturePaper · X

Nov 9, 2025 · 86 followers View post →

All mentions

CHO Cell Papers
@CHOculturePaper · X

Nov 9, 2025 · 86 followers View post →
**Africa Book Link** [https://mailchi.mp/77c66b9fbb83/africa-book ...
Facebook

org/node/28765/discussions/123442/cfp- international-conference- %E2%80 ... 10.1002/leap. 2007 (Posted 11 April 2025) “African women researchers ...

Dec 15, 2025 View →
Bioengineering in Sustainable SSF Food Processing | PDF ...
News

... 28765-6. [75] L. Chen, Z. Zhao, W. Yu, L. Zheng, L. Li ... in radiogenomics for cancers in the era of precision medicine, Cancers 14 (12) org/10.1002/bit.

Dec 15, 2025 View →
1 Nitks Report | PDF
News

DOI: https://doi.org/10.1002/cta.3608, Vol. 51, Issue 8, pp. 3730-3745 ... Bit, Ubuntu 3.28.1)-06. Dell OptiPlex 9010 - Intel (R) Core (TM) i7-3770 CPU ...

Dec 15, 2025 View →
2018 Book AdvancesInSoftComputing PDF | PDF | Metaheuristic ...
News

... 28765-7_79 ... station. The full specs for the Raspberry Pi 3 include: – CPU: Quad-core 64-bit ARM Cortex A53 – Network: 10/100 Mbps Ethernet and 802.11n

Dec 15, 2025 View →
Might be of interest to you or to someone you know. Grab your pdf ...
Facebook

org/node/28765 ... Ideology in Language Use: Pragmatic Guidelines for Empirical Research □ By: Jef Verschueren □ PDF Link: https://bit.ly/41LzoXU.

Sep 12, 2023 View →
New Directions in Cuban Studies Conference Call for Proposals
Facebook

... bit. Anyways, here's the title & abstract of the paper that I'll be ... org/node/28765/discussions/169539/call-papers- rethinking ...

Jun 20, 2023 View →
CACEE 2022-Abstract Book 13.10.22 | PDF | Catalysis | Carbon ...
News

... 10.1002/chem.202202023 2. Adv. Optical Mater. 2022, 10, 2102641 ... 2016, 6, 28765. 203. P-129. Nanomaterials for pre-combustion and post ...

Oct 13, 2022 View →
So excited for “New Critical Directions in Global South Studies," the ...
Facebook

org/node/28765/discussions/123442/cfp- international-conference- %E2 ... Submission details at: https://bit. ly ...

Aug 30, 2021 View →