Mol Neurodegener June 2024 PMID 38890703

Urolithin A promotes p62-dependent lysophagy to prevent acute retinal neurodegeneration.

Juan Ignacio Jiménez-Loygorri, Álvaro Viedma-Poyatos, Raquel Gómez-Sintes, Patricia Boya

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Mentions

Peak: 19 in Jun 2024

across 2 sources since Jun 2024

Extended reach

69,425

potential audience

Total likes

875

Video views

18,191

Mentions per month

Jun 2024 – Dec 2025

Where it's discussed

X / Twitter25 posts
YouTube2 videos

AI synopsis

What people are saying

The discussions primarily emphasize the promising role of Urolithin A in neuroprotection, with phrases like 'prevent acute retinal neurodegeneration' and hashtags such as #Autophagy and #ARMD highlighting its potential medical significance; the tone is generally positive, with some focus on the scientific process, but without extensive critical analysis.

AgreementStrong agreement

Most discussions strongly support the significance of the research, highlighting the potential of Urolithin A in preventing retinal neurodegeneration, suggesting consensus on its importance.

InterestModerate interest

While there is recognition of the study's importance, the overall interest level appears moderate, as most posts focus on sharing the publication rather than exploring broader implications.

EngagementModerate engagement

Discussions include references to specific mechanisms like p62-dependent lysophagy and autophagy, indicating some depth, but lack detailed critique or extensive debate.

ImpactModerate impact

Participants acknowledge the potential of the findings to influence neurodegenerative disease treatment, reflecting perceived moderate to high impact.

Abstract in brief

Age-related macular degeneration (AMD) is a leading cause of blindness in older adults, mainly due to the retina's high energy demands and the need for effective cellular cleanup systems like autophagy.
The natural compound Urolithin A (UA) has shown promise in protecting against neurodegeneration and visual function loss in experimental models of AMD induced by sodium iodate (SI).
UA improves mitochondrial health and autophagic processes, resolving damage from SI by restoring cellular balance, while the disruption of lysosomal function caused by SI can be mitigated by UA through a process called lysophagy.

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All mentions

Urolithin A: A Key to Combating Inflammation and Alzheimer's Disease

We will discuss the amazing molecule Urolithin A, derived from ellagic acid, which shows promise in improving cognitive functions and reducing inflammation. Recent findings highlight its ability to enhance mitophagy and…

Drbeen Medical Lectures · Nov 8, 2024 18,029 views

Urolithin A's Role in Reducing Inflammation and Enhancing Cell Health

We will discuss the amazing molecule Urolithin A. This molecule triggers autophagy to reduce inflammation, promotes mitophagy to heal mitochondrial disease, and triggers lysophagy to improve cellular recycling. It…

React19 · Dec 22, 2025 162 views

Marina García Macia

@Juanaloca2002 · X

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Marina García Macia

@Juanaloca2002 · X

RT @MolNeuro: 'Urolithin A promotes p62-dependent #lysophagy to prevent acute retinal #neurodegeneration' @InaquiConQ Álvaro Viedma-Poyato…

Oct 28, 2024 · 3 shares · 2,814 followers View post →

Women in Autophagy

@WAutophagy · X

RT @MolNeuro: 'Urolithin A promotes p62-dependent #lysophagy to prevent acute retinal #neurodegeneration' @InaquiConQ Álvaro Viedma-Poyato…

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Redox Biology Group

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Marina García Macia

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Aurore Claude-Taupin

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Francisco J Sánchez

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Women in Autophagy

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Molecular Neurodegeneration

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Juan Zapata Muñoz

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Fran

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Patricia Boya

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Cyndi Chua

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Álvaro F. Fernández

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CIB Margarita Salas (CSIC)

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Uri Manor

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Nachoja

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Marina García Macia

@Juanaloca2002 · X

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Jun 18, 2024 · 20 shares · 2,814 followers View post →

Iñaqui Jiménez-Loygorri

@InaquiConQ · X

Our new paper is out!

Jun 18, 2024 · 61 likes · 20 shares · 436 followers View post →

Urolithin A promotes p62-dependent lysophagy to prevent acute retinal neurodegeneration.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Urolithin A: A Key to Combating Inflammation and Alzheimer's Disease

Urolithin A's Role in Reducing Inflammation and Enhancing Cell Health